2017

HSC Niche Biology and HSC Expansion Ex Vivo.
Kumar S, Geiger H.
Trends Mol Med. 2017 Sep 

Septin 6 regulates engraftment and lymphoid differentiation potential of murine long-term hematopoietic stem cells.
Senger K, Marka G, Soller K, Sakk V, Florian MC, Geiger H.
Exp Hematol. 2017 Jul  

Osteopontin attenuates aging-associated phenotypes of hematopoietic stem cells.
Guidi N, Sacma M, Ständker L, Soller K, Marka G, Eiwen K, Weiss JM, Kirchhoff F, Weil T, Cancelas JA, Florian MC, Geiger H.       
EMBO J. 2017 May 

Expression and Activity of the Small RhoGTPase Cdc42 in Blood Cells of Older Adults Are Associated With Age and Cardiovascular Disease.
Florian MC, Klenk J, Marka G, Soller K, Kiryakos H, Peter R, Herbolsheimer F, Rothenbacher D, Denkinger M, Geiger H.  
J Gerontol A Biol Sci Med Sci. 2017 Sep 

Canonical Wnt Signaling Ameliorates Aging of Intestinal Stem Cells.
Nalapareddy K, Nattamai KJ, Kumar RS, Karns R, Wikenheiser-Brokamp KA, Sampson LL, Mahe MM, Sundaram N, Yacyshyn MB, Yacyshyn B, Helmrath MA, Zheng Y, Geiger H.  
Cell Rep. 2017 Mar 

Rejuvenation of aged hematopoietic stem cells.
Guidi N, Geiger H.  
Semin Hematol. 2017 Jan 

2016

Aging of hematopoietic stem cells: DNA damage and mutations?
Moehrle BM, Geiger H.  
Exp Hematol. 2016 Oct 

Aging, Clonality, and Rejuvenation of Hematopoietic Stem Cells.
Akunuru S, Geiger H.  
Trends Mol Med. 2016 Aug 

2015

Stem Cell-Specific Mechanisms Ensure Genomic Fidelity within HSCs and upon Aging of HSCs.
Moehrle BM, Nattamai K, Brown A, Florian MC, Ryan M, Vogel M, Bliederhaeuser C, Soller K, Prows DR, Abdollahi A, Schleimer D, Walter D, Milsom MD, Stambrook P, Porteus M, Geiger H.  
Cell Rep. 2015 Dec 

HSC Aging and Senescent Immune Remodeling.
Denkinger MD, Leins H, Schirmbeck R, Florian MC, Geiger H.  
Trends Immunol. 2015 Dec 

2014

Regulation of hematopoietic stem cell aging by the small RhoGTPase Cdc42.
Geiger H, Zheng Y.  
Exp Cell Res. 2014 Dec 

Hematopoietic stem cell aging.
Geiger H, Denkinger M, Schirmbeck R.  
Curr Opin Immunol. 2014 Aug 

2013

A canonical to non-canonical Wnt signalling switch in haematopoietic stem-cell ageing.
Florian MC, Nattamai KJ, Dörr K, Marka G, Uberle B, Vas V, Eckl C, Andrä I, Schiemann M, Oostendorp RA, Scharffetter-Kochanek K, Kestler HA, Zheng Y, Geiger H.  
Nature. 2013 Nov 

Cdc42 and aging of hematopoietic stem cells.
Geiger H, Zheng Y.  
Curr Opin Hematol. 2013 Jul 

The ageing haematopoietic stem cell compartment.
Geiger H, de Haan G, Florian MC.  
Nat Rev Immunol. 2013 May 

2012

Contribution of an aged microenvironment to aging-associated myeloproliferative disease.
Vas V, Wandhoff C, Dörr K, Niebel A, Geiger H.  
PLoS One. 2012 Feb 

Cdc42 activity regulates hematopoietic stem cell aging and rejuvenation.
Florian MC, Dörr K, Niebel A, Daria D, Schrezenmeier H, Rojewski M, Filippi MD, Hasenberg A, Gunzer M, Scharffetter-Kochanek K, Zheng Y, Geiger H.  
Cell Stem Cell. 2012 May 

Pharmacological targeting of the thrombomodulin-activated protein C pathway mitigates radiation toxicity.
Geiger H, Pawar SA, Kerschen EJ, Nattamai KJ, Hernandez I, Liang HP, Fernández JÁ, Cancelas JA, Ryan MA, Kustikova O, Schambach A, Fu Q, Wang J, Fink LM, Petersen KU, Zhou D, Griffin JH, Baum C, Weiler H, Hauer-Jensen M.  
Nat Med. 2012 Jul 

Aging of the microenvironment influences clonality in hematopoiesis.
Vas V, Senger K, Dörr K, Niebel A, Geiger H.  
PLoS One. 2012 Aug 

2010

Concise review: polarity in stem cells, disease, and aging.
Florian MC, Geiger H.  
Stem Cells. 2010 Sep 

Pharmacological inhibition of EGFR signaling enhances G-CSF-induced hematopoietic stem cell mobilization.
Ryan MA, Nattamai KJ, Xing E, Schleimer D, Daria D, Sengupta A, Köhler A, Liu W, Gunzer M, Jansen M, Ratner N, Le Cras TD, Waterstrat A, Van Zant G, Cancelas JA, Zheng Y, Geiger H.  
Nat Med. 2010 Oct 

2009

Altered cellular dynamics and endosteal location of aged early hematopoietic progenitor cells revealed by time-lapse intravital imaging in long bones.
Köhler A, Schmithorst V, Filippi MD, Ryan MA, Daria D, Gunzer M, Geiger H.  
Blood. 2009 Jul 

Quantification of genomic mutations in murine hematopoietic cells.
Geiger H, David S, Nattamai KJ, Jan V.  
Methods Mol Biol. 2009