BACHELOR/ MASTER THESIS

Cross-over cell biology - informatics

 

We are interested in the molecular mechanisms underlying regulated cellular secretion. We use primary alveolar type II cells a model system to study individual stages of exocytosis with high resolution microscopy (Miklavc et. al. PNAS 108(35):14503-8, Miklavc et. al. J. cell Sci 125(11):2765-74). We are currently looking for a highly motivated and talented individual to establish image analysis tools to improve the analysis of our multidimensional imaging data.

In particular we are interested in applicants with a strong background in informatics or image analysis (e.g. ImageJ, Fiji, …) and a general interest in (cell) biology. Experience or interest in single cell fluorescence microscopy is an advantage. The aim of this project is to implement tools for automated object identification and tracing within a stack/series of microscopic images.

The applicant will join a highly motivated team and benefit from training in a variety of microscopy techniques (multidimensional single cell fluorescence microscopy, TIRF, confocal microscopy,…). Additionally, the successful candidate will have the opportunity to present his/her results at international meetings and in peer-reviewed publications.

Informal enquiries should be addressed to PD Dr. Manfred Frick (manfred.frick(at)uni-ulm.de) at the Institute of General Physiology.