CONGRATULATIONS! Monika Witzenberger from our Munich lab received a PhD award from the Ulmer Universitätsgesellschaft
She received the award for her outstanding work on human TRMT2A.
The Institute of Pharmaceutical Biotechnology
Institute
At our institute we combine structural biology (mainly X-ray crystallography), biophysical approaches, and biochemistry with cell biology to allow for an integrated research approach.
Research topics focus on RNA-based gene regulation in eukaryotes (Niessing), structure-guided inhibitor design (Niessing), and various areas of biotechnology, including biomaterials for medical applications and recombinant biosurfactants for a growing bioeconomy (Rosenau). For more details, please visit the groups subpages under the INSTITUTE/RESEARCH pulldown menue.
_____________________________________________
Master or PhD students, please don't hesitate to contact us directly.
The Niessing lab currently offers Master theses for 2024
News
Puzzle around a protein - The Niessing lab provides important insights into the rare PURA syndrome
Niessing lab publishes study on a neurodevelopmental disorder in the journal Nucleic Acids Research
DFG-FOR2333 conference "RNA Transport Meeting 2022" from Sept. 11.-14. in Düsseldorf
The DFG-funded research network FOR2333 has been organizing an international conference on RNA biology.
Recent Publications
Kissmann, A.K., Bolotnikov, G., Li, R., Müller, F., Xing, H., Krämer,·M., Gottschalk, K.-E., Andersson, J., Weil, T., Rosenau, F. (2024). IMPATIENT‑qPCR: monitoring SELEX success during in vitro aptamer evolution.
Applied Microbiology and Biotechnology 108:284. https://doi.org/10.1007/s00253-024-13085-7
Zhang, Y., Xing, H., Bolotnikov, G., Krämer, M., Bozdogan, A., Kissmann, A.K., Weil, T., Spellerberg, B., Stenger, S., Rosenau, F. (2024). Robust Fluorometric Aptamer Assay for Direct and Rapid Detection of Clinical Isolates of Candida spec.
Int. J. Mol. Sci. 2024, 25, 3444. Doi: 10.3390/ijms25063444
Witzenberger, M., Burczyk, S., Settele, D., Mayer, W., Welp, L.M., Heiss, M., Wagner, M., Monecke, T., Janowski, R., Carell, T., Urlaub, H., Hauck, S.M., Voigt, A.* and Niessing, D.* (2023).
Human TRMT2A methylates tRNA and contributes to translation fidelity.
Nucleic Acids Res. Jul 3;gkad565. Online ahead of print.
https://doi.org/10.1093/nar/gkad565
Lena Molitor*, Melina Klostermann*, Sabrina Bacher, Juliane Merl-Pham, Nadine Spranger, Sandra Burczyk, Carolin Ketteler, Ejona Rusha, Daniel Tews, Anna Pertek, Marcel Proske, Anke Busch, Sarah Reschke, Regina Feederle, Stefanie M Hauck, Helmut Blum, Micha Drukker, Pamela Fischer-Posovszky, Julian König, Kathi Zarnack#, Dierk Niessing#.
Nucleic Acids Research (2023). https://doi.org/10.1093/nar/gkac1237
Informationen zum PURA Syndrom
Head: Prof. Dr. Dierk Niessing
Secretary: Ursula Seifert
tel: ++ 49 / 731 / 50-23161
fax: ++ 49 / 731 / 50-23169
Room N27 2.076
office hours:
Mon: 07:15-15:45
Wed: 07:15-15:54
Thu: 07:15-11:15
Address:
James-Franck-Ring N27; 89081 Ulm
Follow us on Twitter: #theNiessingLabs
The DFG Research Unit FOR2333 " consists of seven German-wide teams (speaker: Ulm University).
_____________________
The DFG Priority Program SPP1935 aims at understanding RNA-bound determinants of posttranscriptional gene regulation.
