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References of Prof. Dr. Klaus-Dieter Spindler

Betanska K., Hönl C., Spindler-Barth M., Spindler K.D. (2011). The importance of exportin and Ran for nucleocytoplasmic shuttling of the ecdysteroid receptor. Arch Insect Biochem Physiol. 76(1):12-21.

Reich M., Spindler K.D., Burret M., Kalbacher H., Boehm B.O., Burster T. (2010). Cathepsin A is expressed in primary human antigen-presenting cells. Immunol Lett. 128(2):143-7.

Betanska K., Czogalla S., Spindler-Barth M., Spindler K. D. (2009). Influence of cell cycle on ecdysteroid receptor in CHO-K1 cells. Arch Insect Biochem Physiol. 72(3):142-53.

Spindler K.D., Hönl C., Tremmel C., Braun S., Ruff H., Spindler-Barth M. (2009). Ecdysteroid hormone action. Cell Mol Life Sci. 66(24):3837-50.

Spindler K.-D., Betanska B., Nieva C., Gwózdz T., Dutko-Gwózdz, Ozyhar A., Spindler-Barth M. (2009). Intracellular Localization of the Ecdystoid Receptor. in: G. Smagghe (Ed.) Ecdysone: Structure and Function. 389-409.

Rinnab L., Schütz S.V., Diesch J., Schmid E., Küfer R., Hautmann R.E., Spindler K.-D., Cronauer M.V. (2008). Inhibition of glycogen synthase kinase-3 in androgen-responsive prostate cancer cell lines: are GSK inhibitors therapeutically useful? Neoplasia. 10(6):624-34.

Rinnab L., Hessenauer A., Schütz S.V., Schmid E., Küfer R., Finter F., Hautmann R.E., Spindler K.D., Cronauer M.V. (2008). Role of androgen receptors in hormone-refractory prostate cancer: molecular basics and experimental therapy approaches. Urologe A. 47(3):314-25. Review. German.

Nieva C., Spindler-Barth M., Spindler K.-D.(2008). Impact of heterodimerization on intracellular localization of the ecdysteroid receptor (EcR). Arch Insect Biochem Physiol. 2008 May;68(1):40-8.

Kredel S., Nienhaus K., Oswald F., Wolff M., Ivanchenko S., Cymer F., Jeromin A., Michel F. J., Spindler K.-D., Heilker R., Nienhaus G. U., Wiedenmann J. (2008). Optimized and far-red-emitting variants of fluorescent protein eqFP611. Chem Biol. 15(3):224-33.

Prowald A., Cronauer M.V., von Klot C., Eilers T., Rinnab L., Herrmann T., Spindler K.-D., Montenarh M., Jonas U., Burchardt M. (2007). Modulation of beta-catenin-mediated TCF-signalling in prostate cancer cell lines by wild-type and mutant p53. Prostate. 2007 67:1751-1760.

Nieva C., Spindler-Barth M., Azoitei A., Spindler K.-D. (2007). Influence of hormone on intracellular localization of the Drosophila melanogaster ecdysteroid receptor (EcR). Cell. Signal. 19: 2582-2587.

Ehrlich H., Maldonado M., Spindler K.D., Eckert C., Hanke T., Born R., Goebel C., Simon P., Heinemann S., Worch H. (2007). First evidence of chitin as a component of the skeletal fibers of marine sponges. Part I. Verongidae (demospongia: Porifera). J Exp Zoolog B Mol Dev Evol. 308(4):347-56.

Betanska K., Nieva C., Spindler-Barth M., Spindler K.-D. Nucleocytoplasmic shuttling of the ecdysteroid receptor (EcR) and of ultraspiracle (Usp) from Drosophila melanogaster in mammalian cells: Energy requirement and interaction with exportin. Arch Insect Biochem Physiol. 65(3):134-42.

Gwozdz T., Dutko-Gwozdz J., Nieva C., Betanska K., Orlowski M., Kowalska A., Dobrucki J., Spindler-Barth M., Spindler K.-D., Ozyhar A. (2006). EcR and Usp, components of the ecdysteroid nuclear receptor complex, exhibit differential distribution of molecular determinants directing subcellular trafficking. Cell Signal. 19(3):490-503

Grossmann G., Jolivet B., Bornand M., Séquin U., Spindler K.-D. (2005). Synthesis and Biological Evaluation of Some Furanones as Putative Chitinase Inhibitors. Synthesis 9: 1543-1549.

Spindler-Barth M., Spindler K-D., Burret M. (2005). 'Easy bleeding' bearing Relations to special Cuticle Structures in Sawfly Larvae (Hymenoptera: Tenthredinidae). Entomologia Generalis 27: 257-268.

Nieva C., Gwozdz T., Dutko-Gwozdz J., Wiedenmann J., Spindler-Barth M., Wieczorek E., Dobrucki J., Dus D., Henrich V., Ozyhar A., Spindler K-D. (2005). Ultraspiracle promotes the nuclear localization of ecdysteroid receptor in mammalian cells. Biol Chem. 386: 463-70.

Wiedenmann J., Ivanchenko S., Oswald F., Schmitt F., Rocker C., Salih A., Spindler K-D, Nienhaus GU. (2004). EosFP, a fluorescent marker protein with UV-inducible green-to-red fluorescence conversion. Proc. Natl. Acad. Sci. U S A, 101: 15905-15910.

Spindler K-D., Greb-Markiewicz B., Polifke T. and Spindler-Barth M. (2004). The functional ecdysteroid receptor complex. Current Topics in Steroid Reseach 4: 123-129

Weidemann W., Cho Y-J., Balz V., Bojar H., Schweikert H-U., Spindler K.-D. (2004). Mutational analysis of the androgen receptor gene in female breast cancer. Current Topics in Steroid Res. 4: 131-135.

Gloeggler, S., Spindler-Barth, M., Ludwig, M., Vorgias, C.E., Spindler, K.-D. (2004). Chitin metabolizing enzymes in insects. Adv. Chitin Science, 7: 43-52.

van Aalten D. M. F., Eijsink V. G. H., Gåseidnes S., Komander D., Rottmann A., Spindler K.-D., Synstad B., Thiele G., Peter M. G.(2003). Structures and Mechanisms of Chitinases. Advan. Chitin Sci., Vol. 5, 1-5

Diesing D., Elmlinger M.W., Schuett B.S., Weidemann W., Romalo G., Schweikert H.U., Spindler K.-D., Ranke M.B. (2003). Genital skin fibroblasts (GF) of patients with androgen insensitivity syndrome express higher insulin-like growth factor binding protein (IGFBP)-2, -3 and -5 than GF of normally virilized males. Hormone Res. 60, 73-78.

Spindler-Barth M. and Spindler, K.-D. (2003). Ecdysteroid receptors (EcR/USP) In: Encyclopedia of hormones and related cell regulators (Eds. Henry, H.L. and Norman, A.W.), Academic Press, p. 466-470.

Thiele G., Rottmann A., Germer A., Kleinpeter E., Spindler K.-D., Synstad B., Eijsink V.G.H., and Peter M.G. (2002). Synthesis of pseudosugar analogues of chitotriose. J. Carbohydrate Chem. 21, 471-489.

Wiedenmann, J., Schenk, A., Röcker, C., Spindler, K.-D., and Nienhaus, G. U. (2002). A far-red fluorescent protein with fast maturation and reduced oligomerization tendency from Entacmaea quadricolor (Cnidaria, Anthozoa, Actinaria). Proc Natl Acad Sci, Proc Natl Acad Sci U.S.A. 99 (18), 11646-11651.

Hanke, H., Lenz, T., Hess, B., Spindler-K.-D., and Weidemann, W. (2001). Effect of testosterone on plaque development and androgen receptor expression in the arterial vessel wall. Circulation 103, 1382-1385.

Spindler, K.-D, Przibilla, S., and Spindler-Barth, M. (2001). Moulting hormones of arthropods: molecular mechanisms. Zoology 103, 189-201.

Hess B, Spindler K.-D., Weidemann, W. and Hanke, H. (2001). Veränderung des Verlaufs der Genexpression in der Aorta unter dem Einfluß von 17ß-Östradiol. In: Determinanten und Beeinflussung der Plaqueentwicklung (Heinle, H., Schulte, H. and Hanefeld, M., eds.), Deutsche Gesellschaft für Arterioskleroseforschung, Tübingen, 122-126.

Elmlinger, M.W., Mayer, I., Schnabel, D., Schütt, B.S., Diesing, D., Romalo, G., Wollmann, H.A., Weidemann, W., Spindler, K.-D., Ranke, M.B. and Schweikert, H.U. (2001). Decreased expression of IGF-II and its binding protein, IGF-binding protein-2, in genital skin fibroblasts of patients with complete androgen insensitivity syndrome compared with normally virilized males. J. Clin. Endocrinol. Metab. 86, 4741-4746.

Spindler K.-D., Romalo, G., Weidemann, W., und Schweikert, H. U. (2001). Hypospadie: Klinik, Endokrinologie und molekularbiologische Aspekte. Reproduktionsmedizin 17, 170-176.

Feix, M., Gloeggler,S., Londershausen, M., Weidemann, W., Spindler, K.-D. and Spindler-Barth, M. (2000). cDNA encoding chitinase from Chironomus tentans (Insecta, Diptera) and its functional expression. Arch. Insect Biochem.Physiol. 45, 24-36.

Feix, M., Hankeln, T., Spindler, K.-D., and Spindler-Barth, M. (2000). cDNA encoding chitinase in the midge, Chironomus tentans. Adv. Chitin Sci. IV, 565-569.

Spindler, K.-D. and Spindler-Barth, M. (2000). Developmental endocrinology of nematoda. In: Reproductive Biology of Invertebrates (K.G. and R.A. Adiyodi), Vol X, Part A: Progress in developmental endocrinology (Dorn, A., ed.) John Wiley & Sons, LTD Chichester, pp. 105-116.

Spindler-Barth, M. and Spindler, K.-D. (2000). Arthropoda - Insecta: Larval development and metamorphosis - molecular aspects. . In: Reproductive Biology of Invertebrates (K.G. and R.A. Adiyodi), Vol X, Part A: Progress in developmental endocrinology (Dorn, A., ed.) John Wiley & Sons, LTD Chichester, pp. 117-144.

Spindler, K.-D., Jaros, P. and Weidemann, W. (2000). Developmental endocrinology of crustacea. In: Reproductive Biology of invertebrates (K.G. and R.A. Adiyodi), Vol X, Part A: Progress in developmental endocrinology (Dorn, A., ed.) John Wiley & Sons, LTD Chichester, pp 243-269.

Wiedenmann, J., Elke, C., Spindler, K.-D. and Funke, W. (2000).Cracks in the beta-can: new fluorescent proteins from Anemonia sulcata. Proc. Natl. Acad. Sci.97, 14091-14096

Elke, C., Rauch, P., Spindler-Barth, M., and Spindler, K.-D. (1999). DNA-binding properties of the ecdysteroid receptor-complex (EcR/USP) of the epithelial cell line from Chironomus tentans. Arch. Insect Biochem. Physiol. 41, 124-133.

Fretz, A. and Spindler, K.-D. (1999). Hormonal regulation of actin and tubulin in an epithelial cell line from Chironomus tentans. Arch. Insect Biochem. Physiol. 41, 71-78.

Mentrup, B., Londershausen, M., Spindler, K.-D. and Weidemann, W. (1999). Isolation and characterization of insect PC2-like prohormone convertase cDNA. Insect Mol. Biol. 8, 305-310.

Peters, I., Weidemann, W., Romalo, G., Knorr, D., Schweikert, H.U., Spindler, K.-D. (1999). An androgen receptor mutation in the direct vicinity of the proposed C-terminal a-helix of the ligand binding domain containing the autonomous transcriptional activating domain (AF-2 AD) is associated with severe (complete) androgen insensitivity. Mol. Cell. Endocrinol. 148, 47-53.

Spindler, K.-D. (1999). Kapitel 12: Endokrinologie. In: Lehrbuch der Entomologie (eds.: K. Dettner und W. Peters), G. Fischer Verlag, Stuttgart, 349-361.

Spindler, K.-D. and Spindler-Barth, M. (1999). Inhibitors of chitinases. In: Chitin and Chitinases (Eds. P. Jollès and R.A.A. Muzzarelli), Birkhäuser Verlag, Basel, 201-209.

Spindler, K.-D., Weidemann, W., und Schweikert, H.U. (1999). Androgenresistenz-syndrome:Klinische, biochemische und molekularbiologische Aspekte. Urologe B, 39, 402-406.

Spindler, K.-D., Jaros, P., and Weidemann, W. Developmental endocrinology of crustacea. In: Progress in developmental endocrinology (Dorn, A., ed.) Wiley-Liss, New York, in press.

Thiele, B., Weidemann, W., Schnabel, D., Romalo, G., Schweikert, H.U., and Spindler, K.-D. (1999). Complete androgen insensitivity due to a new frameshift deletion of two base pairs in exon 1 of the human androgen receptor gene. J. Clin. Endocrinol. Metab. 84, 1751-1753.

Degenhardt, S., Toell, A., Weidemann, W., Dotzenrath, C., Spindler, K.-D. and Grabensee, B. (1998). Point mutations of the human parathyroid calcium receptor gene are not responsible for non-suppressible renal hyperparathyroidism. Kidney Int. 53, 556-561.

Fretz, A., Lezzi, M. and Spindler, K.-D. (1998). Ecdysteroid dependent tissue differentiation and synthesis of cytoskeletal elements in an epithelial cell line from Chironomus tentans. Ann. N. Y. Acad. Sci. 839, 469-471.

Kaiser, A.-M., Wasner, H. and Spindler, K.-D. (1998). Synthesis and action of the cyclic AMP antagonist, prostaglandylinositol cyclic phosphate (cyclic PIP), in Dictyostelium discoideum.Biol. Chem. 379, 727-730.

Lammerding-Köppel, M., Spindler-Barth, M., Steiner, E., Lezzi, M., Drews, U. and Spindler, K.-D. (1998). Immunohistochemical localisation of ecdysteroid receptor and ultraspiracle in the epithelial cell line from Chironomus tentans (Insecta, Diptera). Tissue and Cell 30, 187-194.

Rauch P., Grebe M., Elke C., Spindler K.-D., Spindler-Barth M. (1998). Ecdysteroid receptor and ultraspiracle from Chironomus tentans (insecta) are phosphoproteins and are regulated differently by molting hormone. Insect Biochem. Molec. Biol. 28, 265-275.

Spindler, K.-D., Schweikert, H.U. and Weidemann (1998). The human androgen receptor: mutations and diseases. Current Trends in Steroid Research 1, 83-91.

Spindler-Barth, M., Blattner, R., Vorgias, C. and Spindler, K.-D. (1998). Inhibition of two family 18 chitinases by various allosamidin derivatives. Pest. Sci. 52, 47-52.

Spindler-Barth, M. and Spindler, K.-D. (1998). Ecdysteroid resistant subclones of the epithelial cell line from Chironomus tentans. I. Selection and characterization of the clones. In Vitro Cell. Dev. Biol. Animal 34, 116-122.

Spindler-Barth, M. and Spindler, K.-D. (1998). Morphogenetic actions and mode of action of ecdysteroids in a dipteran cell line. Current Trends in Steroid Research 1, 73-81.

Weidemann, W., Peters, B., Romalo, G., Spindler, K.-D., Schweikert, H.U. (1998). Response to androgen-treatment in a patient with partial androgen insensitivity and a mutation in the DNA-binding domain of the androgen receptor. J. Clin. Endocrinol. Metab. 83, 1173-1176.

Elke, C., Vögtli, M., Rauch, P., Spindler-Barth, M., and Lezzi. M. (1997). Expression of EcR and USP in E. coli: purification and binding to specific DNA sequences, ecdysteroids, and chromosome regions in vitro. Arch. Insect Biochem. Physiol. 35, 59-69.

Spindler, K.- D. (1997). Vergleichende Endokrinologie: Regulation und Mechanismen . 215 S., Thieme-Verlag, Stuttgart

Spindler, K.-D. (1997). Interactions between steroid hormones and the nervous system. NeuroToxicol. 18, 745-754.

Spindler, K.-D. (1997). Chitinase and Chitosanase Assays. In: Chitin Handbook (eds.: R.A.A. Muzzarelli and M.G. Peter) 229-235.

Spindler, K.-D., Feix, M. and Spindler-Barth, M. (1997). Arthropod chitinases. In: Chitin Handbook (eds.: R.A.A. Muzzarelli and M.G. Peter) 249-253.

Spindler, K.-D. and Rapp, C. (1997). Detection of chitin degrading enzymes on gels. In: Chitin Handbook (eds.: R.A.A. Muzzarelli and M.G. Peter) 243-247.

Spindler, K.-D., Spindler-Barth, M. and Sakuda, S. (1997). Effect of demethylation on the chitinase inhibitory activity of allosamidin. Arch. Insect Biochem. Physiol. 36, 223-227.

Spindler-Barth, M., Quack, S., Rauch, P. and Spindler, K.-D. (1997). Biological effects of muristerone A and turkesterone on the epithelial cell line from Chironomus tentans (Insecta, Chironomidae) and correlation with binding affinity to the ecdysteroid receptor. Eur. J. Entomol. 94, 161-169.

Beckmann, M.W., Schweikert, H.-U. and Spindler, K.-D. (1996). Novel aspects of steroid hormone resistance. Symposium of the Sonderforschungsbereich 351. Exp. Clin. Endocrinol. & Diabetes 104, A1-A9.

Spindler, K.-D. and Spindler-Barth, M. (1996). Chitin degradation and synthesis in arthropods. In: Chitin in Life Sciences (Ed. M.M. Giraud-Guille), J. André Publisher, pp. 41-52.

Wegener, S., Spindler-Barth, M. and Spindler, K.-D. (1996). A muscarinic acetylcholine receptor, present in the epithelial cell line from Chironomus tentans. Biol. Chem. 377, 819-824.

Weidemann, W., Linck, B., Haupt, H., Mentrup, B., Romalo, G., Stockklauser, K., Brinkmann, A.O., Schweikert, H.U. and Spindler, K.-D. (1996). Clinical and biochemical investigations and molecular analysis of subjects with mutations in the androgen receptor gene. Clin. Endocrinol. 45, 733-739.

Quack, S. Fretz, A., Spindler-Barth, M. and Spindler, K.-D. (1995). Receptor affinities and biological responses of nonsteroidal ecdysteroid agonists on the epithelial cell line from Chironomus tentans (Diptera: Chironomidae). Eur. J. Entomol. 92, 341-347.

Spindler-Barth, M., Junger, E., Baumeister, R. and Spindler, K.- D. (1995). The epithelial cell line from Chironomus tentans: hormonal regulation of tissue differentiation and cuticle formation. Actes de Colloques 18, 87-93.

Tseneklidou-Stoeter, D., Gerwig, G. J., Kamerling, J. P. and Spindler, K.-D. (1995). Characterization of N-linked carbohydrate chains of the crayfish, Astacus leptodactylus hemocyanin. Biol. Chem. Hoppe-Seyler 376, 531-537.

Wegmann, I., Quack, S., Spindler, K.- D., Dorsch-Häsler, K., Vögtli M. and Lezzi, M. (1995). Immunological studies on the developmental and chromosomal distribution of ecdysteroid receptor protein in Chironomus tentans. Arch. Insect Biochem. Physiol. 30, 95-114.

 

Reich M., Spindler K.D., Burret M., Kalbacher H., Boehm B.O., Burster T. (2010). Cathepsin A is expressed in primary human antigen-presenting cells. Immunol Lett. 128(2):143-7.