Prof. Dr. J. Kassubek - Department of Neurology, Ulm University Medical Center
Research on neuroimaging/magnetic resonance imaging-based techniques, especially applications of diffusion-weighted imaging, i.e. DTI, for the in vivo characterisation of specific alterations of the brain in various neurodegenerative disorders. The focus is on the standardized definition of structural and functional neuroanatomical changes for their use as surrogate markers of the disease. These research efforts are directed at translating the computerized MRI techniques into a standardized application as biomarkers in studies which aim at preventive strategies in neurodegenerative and other neurological diseases, by focussing on early or even preclinical diagnosis and on monitoring disease-modifying interventions.