Zusammenstellung von Bildern aus dem Sonderforschungsbereich
This file was created by the TYPO3 extension publications --- Timezone: CEST Creation date: 2022-10-01 Creation time: 14:36:08 --- Number of references 401 article RN559 Zebrafish fin regeneration requires generic and regeneration-specific responses of osteoblasts to trauma Journal Article 2022 in press (preprint) 10.1101/2022.02.22.481466 bioRxiv Ivonne Sehring Melanie Haffner-Luntzer Anita Ignatius Markus Huber-Lang Gilbert Weidinger article RN554 Inhibition of calcium-triggered secretion by hydrocarbon-stapled peptides Journal Article 2022 10.1038/s41586-022-04543-1 Nature 603 949-956 7903 https://www.ncbi.nlm.nih.gov/pubmed/35322233 Y. Lai G. Fois J. R. Flores M. J. Tuvim Q. Zhou K. Yang J. Leitz J. Peters Y. Zhang R. A. Pfuetzner L. Esquivies P. Jones M. Frick B. F. Dickey A. T. Brunger article RN562 Recent Developments in Mouse Trauma Research Models: A Mini-Review Journal Article 2022 (accepted) 10.3389/fphys.2022.866617 Frontiers in Physiology 13 Adrian Gihring Fabian Gärtner Melanie Schirmer Martin Wabitsch Uwe Knippschild article RN558 Zinc is a key regulator of gastrointestinal development, microbiota composition and inflammation with relevance for autism spectrum disorders Journal Article 2022 10.1007/s00018-021-04052-w Cellular and Molecular Life Sciences 79 18 1 ://WOS:000733875800002 https://link.springer.com/content/pdf/10.1007/s00018-021-04052-w.pdf A. K. Sauer S. Malijauskaite P. Meleady T. M. Boeckers K. McGourty A. M. Grabrucker article RN295 Wnt/beta-catenin signaling acts cell-autonomously to promote cardiomyocyte regeneration in the zebrafish heart Journal Article 2022 10.1016/j.ydbio.2021.11.001 Dev Biol 481 226-237 https://www.ncbi.nlm.nih.gov/pubmed/34748730 A. Bertozzi C. C. Wu S. Hans M. Brand G. Weidinger article RN551 Oligodendrogenesis is a key process for cognitive performance improvement induced by voluntary physical activity Journal Article 2022 10.1002/glia.24155 Glia 70 1052-1067 6 https://www.ncbi.nlm.nih.gov/pubmed/35104015 J. Bernhardi L. Dimou article RN547 Motoneuron-Specific PTEN Deletion in Mice Induces Neuronal Hypertrophy and Also Regeneration after Facial Nerve Injury Journal Article 2022 10.1523/JNEUROSCI.1305-21.2022 J Neurosci 42 2474-2491 12 https://www.ncbi.nlm.nih.gov/pubmed/35149515 S. Meyer Zu Reckendorf D. Moser A. Blechschmidt V. N. Joga D. Sinske J. Hegler S. Deininger A. Catanese S. Vettorazzi G. Antoniadis T. Boeckers B. Knöll article RN302 Mast Cells Trigger Disturbed Bone Healing in Osteoporotic Mice Journal Article 2022 10.1002/jbmr.4455 J Bone Miner Res 37 137-151 1 https://www.ncbi.nlm.nih.gov/pubmed/34633111 V. Fischer D. Ragipoglu J. Diedrich L. Steppe A. Dudeck K. Schutze M. Kalbitz F. Gebhard M. Haffner-Luntzer A. Ignatius article RN303 Interaction between bone and immune cells: Implications for postmenopausal osteoporosis Journal Article 2022 10.1016/j.semcdb.2021.05.014 Semin Cell Dev Biol 123 14-21 https://www.ncbi.nlm.nih.gov/pubmed/34024716 V. Fischer M. Haffner-Luntzer article RN549 Inhibition of Cdk5 increases osteoblast differentiation and bone mass and improves fracture healing Journal Article 2022 10.1038/s41413-022-00195-z Bone Res 10 33 1 https://www.ncbi.nlm.nih.gov/pubmed/35383146 M. Ahmad B. T. Krüger T. Kroll S. Vettorazzi A. K. Dorn F. Mengele S. Lee S. Nandi D. Yilmaz M. Stolz N. K. Tangudu D. C. Vazquez J. Pachmayr I. C. Cirstea M. V. Spasic A. Ploubidou A. Ignatius J. Tuckermann article RN553 Inhibition of Cdk5 Ameliorates Skeletal Bone Loss in Glucocorticoid-Treated Mice Journal Article 2022 10.3390/biomedicines10020404 Biomedicines 10 404 2 https://www.mdpi.com/2227-9059/10/2/404 Benjamin Thilo Krüger Lena Steppe Sabine Vettorazzi Melanie Haffner-Luntzer Sooyeon Lee Ann-Kristin Dorn Anita Ignatius Jan Tuckermann Mubashir Ahmad article RN548 The Pore-Forming Subunit C2IIa of the Binary Clostridium botulinum C2 Toxin Reduces the Chemotactic Translocation of Human Polymorphonuclear Leukocytes Journal Article 2022 10.3389/fphar.2022.810611 Front Pharmacol 13 810611 https://www.ncbi.nlm.nih.gov/pubmed/35222028 J. Eisele S. Schreiner J. Borho S. Fischer S. Heber S. Endres M. Fellermann L. Wohlgemuth M. Huber-Lang G. Fois M. Fauler M. Frick H. Barth article RN552 In Vitro Characterization of Doxorubicin-Mediated Stress-Induced Premature Senescence in Human Chondrocytes Journal Article 2022 10.3390/cells11071106 Cells 11 1106 7 Valeria Kirsch Jan-Moritz Ramge Astrid Schoppa Anita Ignatius Jana Riegger article RN373 Analysis of partial weight bearing after surgical treatment in patients with injuries of the lower extremity Journal Article 2022 10.1007/s00402-020-03588-z Arch Orthop Trauma Surg 142 77-81 1 https://www.ncbi.nlm.nih.gov/pubmed/32880704 A. M. Eickhoff R. Cintean C. Fiedler F. Gebhard K. Schutze P. H. Richter article RN557 Impaired Glucocorticoid Receptor Signaling Aggravates Lung Injury after Hemorrhagic Shock Journal Article 2022 10.3390/cells11010112 Cells 11 112 1 https://www.ncbi.nlm.nih.gov/pubmed/35011674 J. M. Preuss U. Burret M. Gröger S. Kress A. Scheuerle P. Möller J. P. Tuckermann M. Wepler S. Vettorazzi article RN556 A macrophage-hepatocyte glucocorticoid receptor axis coordinates fasting ketogenesis Journal Article 2022 10.1016/j.cmet.2022.01.004 Cell Metab 34 473-486 e9 3 https://www.ncbi.nlm.nih.gov/pubmed/35120589 A. Loft S. F. Schmidt G. Caratti U. Stifel J. Havelund R. Sekar Y. Kwon A. Sulaj K. K. Chow A. J. Alfaro T. Schwarzmayr N. Rittig M. Svart F. F. Tsokanos A. Maida A. Blutke A. Feuchtinger N. Moller M. Blüher P. Nawroth J. Szendrodi N. J. Faergeman A. Zeigerer J. Tuckermann S. Herzig article RN313 A novel in vitro assay to study chondrocyte-to-osteoblast transdifferentiation Journal Article 2022 10.1007/s12020-021-02853-4 Endocrine 75 266-275 1 https://www.ncbi.nlm.nih.gov/pubmed/34529238 M. E. A. Tschaffon S. O. Reber A. Schoppa S. Nandi I. C. Cirstea A. Aszodi A. Ignatius M. Haffner-Luntzer article RN561 Adipose tissue: a neglected organ in the response to severe trauma? Journal Article 2022 10.1007/s00018-022-04234-0 Cell Mol Life Sci 79 207 4 https://www.ncbi.nlm.nih.gov/pubmed/35338424 L. Wrba R. Halbgebauer J. Roos M. Huber-Lang P. Fischer-Posovszky article RN560 Bone Mass and Osteoblast Activity Are Sex-Dependent in Mice Lacking the Estrogen Receptor & in Chondrocytes and Osteoblast Progenitor Cells Journal Article 2022 doi:10.3390/ijms23052902 International Journal of Molecular Sciences 23 2902 5 https://www.mdpi.com/1422-0067/23/5/2902 Lena Steppe Jasmin Bülow Jan Tuckermann Anita Ignatius Melanie Haffner-Luntzer article RN550 Channels and Transporters of the Pulmonary Lamellar Body in Health and Disease Journal Article 2022 10.3390/cells11010045 Cells 11 45 1 https://www.ncbi.nlm.nih.gov/pubmed/35011607 P. Dietl M. Frick article RN555 Distinct Glucocorticoid Receptor Actions in Bone Homeostasis and Bone Diseases Journal Article 2022 10.3389/fendo.2021.815386 Frontiers in Endocrinology 12 1887 https://www.frontiersin.org/article/10.3389/fendo.2021.815386 Sooyeon Lee Benjamin Thilo Krüger Anita Ignatius Jan Tuckermann article RN294 Effects of Sodium Thiosulfate During Resuscitation from Trauma-and-Hemorrhage in Cystathionine gamma-Lyase (CSE) Knockout Mice Journal Article 2022 10.1097/SHK.0000000000001828 Shock 57 131-139 1 https://www.ncbi.nlm.nih.gov/pubmed/34172609 M. Gröger M. Hogg E. Abdelsalam S. Kress A. Hoffmann B. Stahl V. Saub N. Denoix O. McCook E. Calzia E. M. Wolfschmitt U. Wachter J. A. Vogt R. Wang P. Radermacher T. Merz B. L. Nussbaum article RN297 Glucocorticoids coordinate macrophage metabolism through the regulation of the tricarboxylic acid cycle Journal Article 2022 10.1016/j.molmet.2021.101424 Mol Metab 57 101424 https://www.ncbi.nlm.nih.gov/pubmed/34954109 U. Stifel E. M. Wolfschmitt J. Vogt U. Wachter S. Vettorazzi D. Tews M. Hogg F. Zink N. M. Koll S. Winning R. Mounier B. Chazaud P. Radermacher P. Fischer-Posovszky G. Caratti J. Tuckermann article RN308 Non-union bone fractures Journal Article 2021 10.1038/s41572-021-00289-8 Nat Rev Dis Primers 7 57 1 https://www.ncbi.nlm.nih.gov/pubmed/34354083 B. Wildemann A. Ignatius F. Leung L. A. Taitsman R. M. Smith R. Pesantez M. J. Stoddart R. G. Richards J. B. Jupiter article RN325 Ion and Water Transport in Neutrophil Granulocytes and Its Impairment during Sepsis Journal Article 2021 10.3390/ijms22041699 Int J Mol Sci 22 1699 4 https://www.ncbi.nlm.nih.gov/pubmed/33567720 https://mdpi-res.com/d_attachment/ijms/ijms-22-01699/article_deploy/ijms-22-01699-v2.pdf D. A. C. Messerer H. Schmidt M. Frick M. Huber-Lang article RN312 NG2-Glia Transiently Overcome Their Homeostatic Network and Contribute to Wound Closure After Brain Injury Journal Article 2021 10.3389/fcell.2021.662056 Frontiers in Cell and Developmental Biology 9 15 ://WOS:000651154900001 A. Streitberg S. Jakel J. E. Bernhardi C. Straube F. Buggenthin C. Marr L. Dimou article RN328 Mouse Intensive Care Unit (MICU) Journal Article 2021 10.1007/978-1-0716-1488-4_11 Methods Mol Biol 2321 121-135 https://www.ncbi.nlm.nih.gov/pubmed/34048012 https://link.springer.com/content/pdf/10.1007%2F978-1-0716-1488-4_11.pdf T. Merz S. Kress M. Gröger P. Radermacher O. McCook article RN329 Localization of the hydrogen sulfide and oxytocin systems at the depth of the sulci in a porcine model of acute subdural hematoma Journal Article 2021 10.4103/1673-5374.313018 Neural Regen Res 16 2376-2382 12 https://www.ncbi.nlm.nih.gov/pubmed/33907009 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8374554/pdf/NRR-16-2376.pdf O. McCook A. Scheuerle N. Denoix T. Kapapa P. Radermacher T. Merz article RN339 Leukemia inhibitory factor treatment attenuates the detrimental effects of glucocorticoids on bone in mice Journal Article 2021 10.1016/j.bone.2021.115843 Bone 145 115843 https://www.ncbi.nlm.nih.gov/pubmed/33429108 S. Lee P. Liu M. Ahmad J. P. Tuckermann article RN367 Is zebrafish heart regeneration "complete"? Lineage-restricted cardiomyocytes proliferate to pre-injury numbers but some fail to differentiate in fibrotic hearts Journal Article 2021 10.1016/j.ydbio.2020.12.004 Dev Biol 471 106-118 https://www.ncbi.nlm.nih.gov/pubmed/33309949 A. Bertozzi C. C. Wu P. D. Nguyen M. D. Vasudevarao M. A. Mulaw C. D. Koopman T. P. Boer J. Bakkers G. Weidinger article RN326 Immunopathophysiology of trauma-related acute kidney injury Journal Article 2021 10.1038/s41581-020-00344-9 Nat Rev Nephrol 17 91-111 2 https://www.ncbi.nlm.nih.gov/pubmed/32958893 https://www.nature.com/articles/s41581-020-00344-9 D. A. C. Messerer R. Halbgebauer B. Nilsson H. Pavenstadt P. Radermacher M. Huber-Lang article RN368 Interleukin 8 Elicits Rapid Physiological Changes in Neutrophils That Are Altered by Inflammatory Conditions Journal Article 2021 10.1159/000514885 J Innate Immun 13 225-241 4 https://www.ncbi.nlm.nih.gov/pubmed/33857948 https://www.karger.com/Article/Pdf/514885 S. Bernhard S. Hug A. E. P. Stratmann M. Erber L. Vidoni C. L. Knapp B. D. Thomass M. Fauler B. Nilsson K. Nilsson Ekdahl K. Fohr C. K. Braun L. Wohlgemuth M. Huber-Lang D. A. C. Messerer article RN348 Intact Glucocorticoid Receptor Dimerization Is Deleterious in Trauma-Induced Impaired Fracture Healing Journal Article 2021 10.3389/fimmu.2020.628287 Front Immunol 11 628287 https://www.frontiersin.org/article/10.3389/fimmu.2020.628287 Yasmine Hachemi Anna E. Rapp Sooyeon Lee Ann-Kristin Dorn Benjamin T. Krüger Kathrin Kaiser Anita Ignatius Jan Tuckermann article RN363 Inhibition of sphingosine 1-phosphate protects mice against chondrocyte catabolism and osteoarthritis Journal Article 2021 10.1016/j.joca.2021.06.001 Osteoarthritis Cartilage 29 1335-1345 9 https://www.ncbi.nlm.nih.gov/pubmed/34144150 C. Cherifi A. Latourte S. Vettorazzi J. Tuckermann S. Provot H. K. Ea A. Ledoux J. Casas O. Cuvillier P. Richette A. Ostertag E. Hay M. Cohen-Solal article RN335 Increased Presence of Complement Factors and Mast Cells in Alveolar Bone and Tooth Resorption Journal Article 2021 10.3390/ijms22052759 Int J Mol Sci 22 2759 5 https://www.ncbi.nlm.nih.gov/pubmed/33803323 https://mdpi-res.com/d_attachment/ijms/ijms-22-02759/article_deploy/ijms-22-02759.pdf K. Luntzer I. Lackner B. Weber Y. Mödinger A. Ignatius F. Gebhard S. Y. Mihaljevic M. Haffner-Luntzer M. Kalbitz article RN341 In Vitro Measurements of Cellular Forces and their Importance in the Lung-From the Sub- to the Multicellular Scale Journal Article 2021 10.3390/life11070691 Life (Basel) 11 691 7 https://www.ncbi.nlm.nih.gov/pubmed/34357063 https://mdpi-res.com/d_attachment/life/life-11-00691/article_deploy/life-11-00691.pdf P. Kolb A. Schundner M. Frick K. E. Gottschalk article RN307 IKK2/NF-kappaB Activation in Astrocytes Reduces amyloid beta Deposition: A Process Associated with Specific Microglia Polarization Journal Article 2021 10.3390/cells10102669 Cells 10 2669 10 https://www.ncbi.nlm.nih.gov/pubmed/34685649 https://mdpi-res.com/d_attachment/cells/cells-10-02669/article_deploy/cells-10-02669-v3.pdf S. Yang A. Magnutzki N. O. Alami M. Lattke T. M. Hein J. S. Scheller C. Kroger F. Oswald D. Yilmazer-Hanke T. Wirth B. Baumann article RN366 Histone deacetylase 1 controls cardiomyocyte proliferation during embryonic heart development and cardiac regeneration in zebrafish Journal Article 2021 10.1371/journal.pgen.1009890 PLoS Genet 17 e1009890 11 https://www.ncbi.nlm.nih.gov/pubmed/34723970 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8584950/pdf/pgen.1009890.pdf A. Bühler B. M. Gahr D. D. Park A. Bertozzi A. Boos M. Dalvoy A. Pott F. Oswald R. A. Kovall B. Kühn G. Weidinger W. Rottbauer S. Just article RN334 Persistent JunB activation in fibroblasts disrupts stem cell niche interactions enforcing skin aging Journal Article 2021 10.1016/j.celrep.2021.109634 Cell Rep 36 109634 9 https://www.ncbi.nlm.nih.gov/pubmed/34469740 P. Maity K. Singh L. Krug A. Koroma A. Hainzl W. Bloch S. Kochanek M. Wlaschek M. Schorpp-Kistner P. Angel A. Ignatius H. Geiger K. Scharffetter-Kochanek article RN350 Obesity Prolongs the Inflammatory Response in Mice After Severe Trauma and Attenuates the Splenic Response to the Inflammatory Reflex Journal Article 2021 10.3389/fimmu.2021.745132 Frontiers in Immunology 12 Fabian Gärtner Adrian Gihring Aileen Roth Joachim Bischof Pengfei Xu Leonard Elad Martin Wabitsch Timo Burster Uwe Knippschild article RN333 Temporal-spatial organ response after blast-induced experimental blunt abdominal trauma Journal Article 2021 10.1096/fj.202100995R FASEB J 35 e22038 12 https://www.ncbi.nlm.nih.gov/pubmed/34748229 https://faseb.onlinelibrary.wiley.com/doi/pdfdirect/10.1096/fj.202100995R?download=true A. Maitz F. Haussner S. Braumuller A. Hoffmann L. Lupu U. Wachter P. Radermacher C. K. Braun H. J. Wilke M. Vogt A. Ignatius R. Halbgebauer L. Bettac T. F. E. Barth M. Huber-Lang A. Palmer article RN351 Pharmacological targeting of host chaperones protects from pertussis toxin in vitro and in vivo Journal Article 2021 10.1038/s41598-021-84817-2 Sci Rep 11 5429 1 https://www.ncbi.nlm.nih.gov/pubmed/33686161 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7940712/pdf/41598_2021_Article_84817.pdf K. Ernst A. K. Mittler V. Winkelmann C. Kling N. Eberhardt A. Anastasia M. Sonnabend R. Lochbaum J. Wirsching M. Sakari A. T. Pulliainen C. Skerry N. H. Carbonetti M. Frick H. Barth article RN357 Target arterial PO2 according to the underlying pathology: a mini-review of the available data in mechanically ventilated patients Journal Article 2021 10.1186/s13613-021-00872-y Ann Intensive Care 11 88 1 https://www.ncbi.nlm.nih.gov/pubmed/34076802 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8170650/pdf/13613_2021_Article_872.pdf J. Demiselle E. Calzia C. Hartmann D. A. C. Messerer P. Asfar P. Radermacher T. Datzmann article RN300 Zebrafish Fin: Complex Molecular Interactions and Cellular Mechanisms Guiding Regeneration Journal Article 2021 10.1101/cshperspect.a040758 Cold Spring Harb Perspect Biol https://www.ncbi.nlm.nih.gov/pubmed/34649924 I. Sehring G. Weidinger article RN310 Trauma, a Matter of the Heart-Molecular Mechanism of Post-Traumatic Cardiac Dysfunction Journal Article 2021 10.3390/ijms22020737 Int J Mol Sci 22 737 2 https://www.ncbi.nlm.nih.gov/pubmed/33450984 https://mdpi-res.com/d_attachment/ijms/ijms-22-00737/article_deploy/ijms-22-00737.pdf B. Weber I. Lackner F. Gebhard T. Miclau M. Kalbitz article RN318 The Role of Glucocorticoids in Inflammatory Diseases Journal Article 2021 10.3390/cells10112921 Cells 10 2921 11 https://www.ncbi.nlm.nih.gov/pubmed/34831143 https://mdpi-res.com/d_attachment/cells/cells-10-02921/article_deploy/cells-10-02921.pdf S. D. Reichardt A. Amouret C. Muzzi S. Vettorazzi J. P. Tuckermann F. Luhder H. M. Reichardt article RN336 The Outcome of Critically Ill COVID-19 Patients Is Linked to Thromboinflammation Dominated by the Kallikrein/Kinin System Journal Article 2021 10.3389/fimmu.2021.627579 Front Immunol 12 627579 https://www.ncbi.nlm.nih.gov/pubmed/33692801 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7937878/pdf/fimmu-12-627579.pdf M. Lipcsey B. Persson O. Eriksson A. M. Blom K. Fromell M. Hultstrom M. Huber-Lang K. N. Ekdahl R. Frithiof B. Nilsson article RN286 The cytotoxic effect of Clostridioides difficile pore-forming toxin CDTb Journal Article 2021 10.1016/j.bbamem.2021.183603 Biochim Biophys Acta Biomembr 1863 183603 6 https://www.ncbi.nlm.nih.gov/pubmed/33689753 M. Landenberger J. Nieland M. Roeder K. Norgaard P. Papatheodorou K. Ernst H. Barth article RN358 Hemorrhagic Shock Induces a Rapid Transcriptomic Shift of the Immune Balance in Leukocytes after Experimental Multiple Injury Journal Article 2021 10.1155/2021/6654318 Mediators Inflamm 2021 6654318 https://www.ncbi.nlm.nih.gov/pubmed/33574730 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7857921/pdf/MI2021-6654318.pdf L. Debler A. Palmer S. Braumuller B. Klohs T. E. Mollnes K. Holzmann M. Huber-Lang R. Halbgebauer article RN365 Synaptic disruption and CREB-regulated transcription are restored by K(+) channel blockers in ALS Journal Article 2021 10.15252/emmm.202013131 EMBO Mol Med 13 e13131 7 https://www.ncbi.nlm.nih.gov/pubmed/34125498 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8261490/pdf/EMMM-13-e13131.pdf A. Catanese S. Rajkumar D. Sommer D. Freisem A. Wirth A. Aly D. Massa-Lopez A. Olivieri F. Torelli V. Ioannidis J. Lipecka I. C. Guerrera D. Zytnicki A. Ludolph E. Kabashi M. A. Mulaw F. Roselli T. M. Böckers article RN322 RNF40 exerts stage-dependent functions in differentiating osteoblasts and is essential for bone cell crosstalk Journal Article 2021 10.1038/s41418-020-00614-w Cell Death Differ 28 700-714 2 https://www.ncbi.nlm.nih.gov/pubmed/32901120 https://www.nature.com/articles/s41418-020-00614-w.pdf Z. Najafova P. Liu F. Wegwitz M. Ahmad L. Tamon R. L. Kosinsky W. Xie S. A. Johnsen J. Tuckermann article RN353 Sorting Nexin 10 as a Key Regulator of Membrane Trafficking in Bone-Resorbing Osteoclasts: Lessons Learned From Osteopetrosis Journal Article 2021 10.3389/fcell.2021.671210 Front Cell Dev Biol 9 671210 https://www.ncbi.nlm.nih.gov/pubmed/34095139 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8173195/pdf/fcell-09-671210.pdf A. Elson M. Stein G. Rabie M. Barnea-Zohar S. Winograd-Katz N. Reuven M. Shalev J. Sekeres M. Kanaan J. Tuckermann B. Geiger article RN299 Small Extracellular Vesicles Propagate the Inflammatory Response After Trauma Journal Article 2021 10.1002/advs.202102381 Adv Sci (Weinh) 8 e2102381 24 https://www.ncbi.nlm.nih.gov/pubmed/34713625 T. Seibold J. Schönfelder F. Weeber A. Lechel M. Armacki M. Waldenmaier C. Wille A. Palmer R. Halbgebauer E. Karasu M. Huber-Lang M. Kalbitz P. Radermacher S. Paschke T. Seufferlein T. Eiseler article RN315 Simultaneous Measurement of Changes in Neutrophil Granulocyte Membrane Potential, Intracellular pH, and Cell Size by Multiparametric Flow Cytometry Journal Article 2021 10.3390/biomedicines9111504 Biomedicines 9 1504 11 https://www.ncbi.nlm.nih.gov/pubmed/34829733 https://mdpi-res.com/d_attachment/biomedicines/biomedicines-09-01504/article_deploy/biomedicines-09-01504-v4.pdf A. E. P. Stratmann L. Wohlgemuth M. E. Erber S. Bernhard S. Hug M. Fauler L. Vidoni A. O. K. Mohamed B. D. Thomass F. Munnich L. Stukan K. J. Fohr M. Mannes M. S. Huber-Lang D. A. C. Messerer article RN301 Short-term outcome of fragility fractures of the pelvis in the elderly treated with screw osteosynthesis and external fixator Journal Article 2021 10.1007/s00068-021-01780-3 Eur J Trauma Emerg Surg https://www.ncbi.nlm.nih.gov/pubmed/34545420 K. Schuetze A. Eickhoff C. Dehner A. Blidon F. Gebhard P. H. Richter article RN323 Segmental involvement of the corpus callosum in C9orf72-associated ALS: a tract of interest-based DTI study Journal Article 2021 10.1177/20406223211002969 Ther Adv Chronic Dis 12 20406223211002969 https://www.ncbi.nlm.nih.gov/pubmed/33815737 https://journals.sagepub.com/doi/pdf/10.1177/20406223211002969 H. P. Muller D. Lule F. Roselli A. Behler A. C. Ludolph J. Kassubek article RN360 S100B dysregulation during brain development affects synaptic SHANK protein networks via alteration of zinc homeostasis Journal Article 2021 10.1038/s41398-021-01694-z Translational Psychiatry 11 13 1 ://WOS:000731670100001 https://www.nature.com/articles/s41398-021-01694-z.pdf E. Daini S. Hagmeyer C. A. De Benedictis J. S. Cristovao M. Bodria A. M. Ross A. Raab T. M. Boeckers J. Feldmann C. M. Gomes M. Zoli A. Vilella A. M. Grabrucker article RN364 Role of the C5a-C5a receptor axis in the inflammatory responses of the lungs after experimental polytrauma and hemorrhagic shock Journal Article 2021 10.1038/s41598-020-79607-1 Sci Rep 11 2158 1 https://www.ncbi.nlm.nih.gov/pubmed/33495506 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7835219/pdf/41598_2020_Article_79607.pdf S. Chakraborty V. E. Winkelmann S. Braumuller A. Palmer A. Schultze B. Klohs A. Ignatius A. Vater M. Fauler M. Frick M. Huber-Lang article RN354 Hemorrhagic shock induces renal complement activation Journal Article 2021 10.1007/s00068-019-01187-1 Eur J Trauma Emerg Surg 47 373-380 2 https://www.ncbi.nlm.nih.gov/pubmed/31309238 https://link.springer.com/content/pdf/10.1007/s00068-019-01187-1.pdf C. Ehrnthaller A. Schultze G. Wakileh T. Neff S. Häfner P. Radermacher M. Huber-Lang article RN340 Systemic and local cardiac inflammation after experimental long bone fracture, traumatic brain injury and combined trauma in mice Journal Article 2021 10.1016/j.jot.2020.12.003 J Orthop Translat 28 39-46 https://www.ncbi.nlm.nih.gov/pubmed/33717980 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7906881/pdf/main.pdf I. Lackner B. Weber M. Haffner-Luntzer S. Hristova F. Gebhard C. Lam K. Morioka R. S. Marcucio T. Miclau M. Kalbitz article RN359 H2S as a Therapeutic Adjuvant Against COVID-19: Why and How? Journal Article 2021 10.1097/SHK.0000000000001723 Shock 56 865-867 5 https://www.ncbi.nlm.nih.gov/pubmed/33443365 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8518209/pdf/shk-56-865.pdf T. Datzmann T. Merz O. McCook C. Szabo P. Radermacher article RN319 Acute TBK1/IKK-epsilon Inhibition Enhances the Generation of Disease-Associated Microglia-Like Phenotype Upon Cortical Stab-Wound Injury Journal Article 2021 10.3389/fnagi.2021.684171 Front Aging Neurosci 13 684171 https://www.ncbi.nlm.nih.gov/pubmed/34326766 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8313992/pdf/fnagi-13-684171.pdf R. Rehman L. Tar A. J. Olamide Z. Li J. Kassubek T. Böckers J. Weishaupt A. Ludolph D. Wiesner F. Roselli article RN355 Complement Factor C5a Inhibits Apoptosis of Neutrophils-A Mechanism in Polytrauma? Journal Article 2021 10.3390/jcm10143157 J Clin Med 10 3157 14 https://www.ncbi.nlm.nih.gov/pubmed/34300323 https://mdpi-res.com/d_attachment/jcm/jcm-10-03157/article_deploy/jcm-10-03157-v2.pdf C. Ehrnthaller S. Braumuller S. Kellermann F. Gebhard M. Perl M. Huber-Lang article RN331 Complement as driver of systemic inflammation and organ failure in trauma, burn, and sepsis Journal Article 2021 10.1007/s00281-021-00872-x Semin Immunopathol 43 773-788 6 https://www.ncbi.nlm.nih.gov/pubmed/34191093 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8243057/pdf/281_2021_Article_872.pdf M. Mannes C. Q. Schmidt B. Nilsson K. N. Ekdahl M. Huber-Lang article RN352 Characterization and Pharmacological Inhibition of the Pore-Forming Clostridioides difficile CDTb Toxin Journal Article 2021 10.3390/toxins13060390 Toxins (Basel) 13 390 6 https://www.ncbi.nlm.nih.gov/pubmed/34071730 https://mdpi-res.com/d_attachment/toxins/toxins-13-00390/article_deploy/toxins-13-00390-v2.pdf K. Ernst M. Landenberger J. Nieland K. Norgaard M. Frick G. Fois R. Benz H. Barth article RN343 Changes in Functional Glucocorticoid Sensitivity of Isolated Splenocytes Induced by Chronic Psychosocial Stress - A Time Course Study Journal Article 2021 10.3389/fimmu.2021.753822 Front Immunol 12 753822 https://www.ncbi.nlm.nih.gov/pubmed/34675935 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8523951/pdf/fimmu-12-753822.pdf E. Kempter M. Amoroso H. L. Duffner A. M. Werner D. Langgartner S. Kupfer S. O. Reber article RN327 Biological Connection of Psychological Stress and Polytrauma under Intensive Care: The Role of Oxytocin and Hydrogen Sulfide Journal Article 2021 10.3390/ijms22179192 Int J Mol Sci 22 9192 17 https://www.ncbi.nlm.nih.gov/pubmed/34502097 https://mdpi-res.com/d_attachment/ijms/ijms-22-09192/article_deploy/ijms-22-09192-v2.pdf T. Merz O. McCook N. Denoix P. Radermacher C. Waller T. Kapapa article RN298 Angiogenin Released from ABCB5(+) Stromal Precursors Improves Healing of Diabetic Wounds by Promoting Angiogenesis Journal Article 2021 10.1016/j.jid.2021.10.026 J Invest Dermatol https://www.ncbi.nlm.nih.gov/pubmed/34808236 K. Singh P. Maity A. K. Koroma A. Basu R. K. Pandey S. Vander Beken P. Haas L. Krug A. Hainzl A. Sindrilaru C. Pfeiffer M. Wlaschek N. Y. Frank M. H. Frank C. Ganss A. Banvolgyi N. Wikonkal S. Eming I. Pastar M. Tomic-Canic M. A. Kluth K. Scharffetter-Kochanek article RN370 An SNX10-dependent mechanism downregulates fusion between mature osteoclasts Journal Article 2021 10.1242/jcs.254979 J Cell Sci 134 jcs254979 9 https://www.ncbi.nlm.nih.gov/pubmed/33975343 https://cob.silverchair-cdn.com/cob/content_public/journal/jcs/134/9/10.1242_jcs.254979/5/jcs254979.pdf?Expires=1643710970&Signature=rp4J8tPdKhrc--7Fhh6nMxcud-7hCNgjeUCrdGmqHeI2y7TstTzd6~L8DgR1daDRzS9dVAqrJIMy M. Barnea-Zohar S. E. Winograd-Katz M. Shalev E. Arman N. Reuven L. Roth O. Golani M. Stein F. Thalji M. Kanaan J. Tuckermann B. Geiger A. Elson article RN297 Glucocorticoids Coordinate Macrophage Metabolism Through Regulation of the Tricarboxylic Acid Cycle Journal Article 2021 in press 10.1016/j.molmet.2021.101424 Mol Metab 101424 https://www.ncbi.nlm.nih.gov/pubmed/34954109 U. Stifel E. M. Wolfschmitt J. Vogt U. Wachter S. Vettorazzi D. Tews M. Hogg F. Zink N. M. Koll S. Winning R. Mounier B. Chazaud P. Radermacher P. Fischer-Posovszky G. Caratti J. Tuckermann article RN332 Complement inhibition at the level of C3 or C5: mechanistic reasons for ongoing terminal pathway activity Journal Article 2021 10.1182/blood.2020005959 Blood 137 443-455 4 https://www.ncbi.nlm.nih.gov/pubmed/33507296 https://ashpublications.org/blood/article-abstract/137/4/443/474570/Complement-inhibition-at-the-level-of-C3-or-C5?redirectedFrom=fulltext M. Mannes A. Dopler O. Zolk S. J. Lang R. Halbgebauer B. Hochsmann A. Skerra C. K. Braun M. Huber-Lang H. Schrezenmeier C. Q. Schmidt article RN349 Activation of the medial preoptic area (MPOA) ameliorates loss of maternal behavior in a Shank2 mouse model for autism Journal Article 2021 10.15252/embj.2019104267 Embo Journal 40 19 5 ://WOS:000611155300001 https://www.embopress.org/doi/full/10.15252/embj.2019104267 S. Grabrucker J. Pagano J. Schweizer C. Urrutia-Ruiz M. Schon K. Thome G. Ehret A. M. Grabrucker R. Zhang B. Hengerer J. Bockmann C. Verpelli C. Sala T. M. Boeckers article RN344 Activation of Neutrophil Granulocytes by Platelet-Activating Factor Is Impaired During Experimental Sepsis Journal Article 2021 10.3389/fimmu.2021.642867 Front Immunol 12 642867 https://www.ncbi.nlm.nih.gov/pubmed/33796110 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8007865/pdf/fimmu-12-642867.pdf S. Hug S. Bernhard A. E. P. Stratmann M. Erber L. Wohlgemuth C. L. Knapp J. M. Bauer L. Vidoni M. Fauler K. J. Fohr P. Radermacher A. Hoffmann M. Huber-Lang D. A. C. Messerer article RN317 Accuracy of screw stabilization of the dorsal pelvic ring using a hybrid operating room: 5 Year experience in a level 1 trauma center Journal Article 2021 10.1016/j.injury.2021.06.024 Injury 52 2968-2972 10 https://www.ncbi.nlm.nih.gov/pubmed/34275645 P. H. Richter A. Blidon A. Eickhoff F. Gebhard K. Schuetze article RN361 A CRHR1 antagonist prevents synaptic loss and memory deficits in a trauma-induced delirium-like syndrome Journal Article 2021 10.1038/s41380-020-0659-y Mol Psychiatry 26 3778-3794 8 https://www.ncbi.nlm.nih.gov/pubmed/32051550 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8550963/pdf/41380_2020_Article_659.pdf S. Cursano C. R. Battaglia C. Urrutia-Ruiz S. Grabrucker M. Schon J. Bockmann S. Braumuller P. Radermacher F. Roselli M. Huber-Lang T. M. Boeckers article RN338 A complex intervention to promote prevention of delirium in older adults by targeting caregiver's participation during and after hospital discharge - study protocol of the TRAnsport and DElirium in older people (TRADE) project Journal Article 2021 10.1186/s12877-021-02585-0 BMC Geriatr 21 646 1 https://www.ncbi.nlm.nih.gov/pubmed/34784883 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8594294/pdf/12877_2021_Article_2585.pdf C. Leinert S. Brefka U. Braisch N. Denninger M. Mueller P. Benzinger J. Bauer A. Bahrmann N. Frey H. A. Katus T. Geisler G. Eschweiler J. Klaus T. Seufferlein K. Schuetze F. Gebhard J. Dreyhaupt R. Muche K. Pahmeier J. Biermann-Stallwitz J. Wasem L. Flagmeier D. Dallmeier M. Denkinger article RN305 Inhibition of Cdk5 increases osteoblast differentiation and bone mass and improves fracture healing Journal Article 2021 accepted Bone Research Anita Ignatius Mubashir Ahmad Jan Tuckermann. article RN330 H2S and Oxytocin Systems in Early Life Stress and Cardiovascular Disease Journal Article 2021 10.3390/jcm10163484 J Clin Med 10 3484 16 https://www.ncbi.nlm.nih.gov/pubmed/34441780 https://mdpi-res.com/d_attachment/jcm/jcm-10-03484/article_deploy/jcm-10-03484-v2.pdf O. McCook N. Denoix P. Radermacher C. Waller T. Merz article RN345 Complement in Trauma - Traumatised Complement? Journal Article 2021 10.1111/bph.15245 Br J Pharmacol 178 2863-2879 14 https://www.ncbi.nlm.nih.gov/pubmed/32880897 M. S. Huber-Lang A. Ignatius J. Kohl M. Mannes C. K. Braun article RN296 A guide to changing paradigms of glucocorticoid receptor function-a model system for genome regulation and physiology Journal Article 2021 10.1111/febs.16100 FEBS J https://www.ncbi.nlm.nih.gov/pubmed/34213830 S. Vettorazzi D. Nalbantoglu J. C. M. Gebhardt J. Tuckermann article RN316 Cytoplasmic FUS triggers early behavioral alterations linked to cortical neuronal hyperactivity and inhibitory synaptic defects Journal Article 2021 10.1038/s41467-021-23187-9 Nat Commun 12 3028 1 https://www.ncbi.nlm.nih.gov/pubmed/34021132 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8140148/pdf/41467_2021_Article_23187.pdf J. Scekic-Zahirovic I. Sanjuan-Ruiz V. Kan S. Megat P. De Rossi S. Dieterle R. Cassel M. Jamet P. Kessler D. Wiesner L. Tzeplaeff V. Demais S. Sahadevan K. M. Hembach H. P. Muller G. Picchiarelli N. Mishra S. Antonucci S. Dirrig-Grosch J. Kassubek V. Rasche A. Ludolph A. L. Boutillier F. Roselli M. Polymenidou C. Lagier-Tourenne S. Liebscher L. Dupuis article RN311 Early myocardial damage (EMD) and valvular insufficiency result in impaired cardiac function after multiple trauma in pigs Journal Article 2021 10.1038/s41598-020-80409-8 Sci Rep 11 1151 1 https://www.ncbi.nlm.nih.gov/pubmed/33441945 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7806767/pdf/41598_2020_Article_80409.pdf B. Weber I. Lackner M. Baur F. Gebhard R. Pfeifer P. Cinelli S. Halvachizadeh M. Teuben H. C. Pape A. Imhof M. Lipiski N. Cesarovic M. Kalbitz article RN304 Dangers of hyperoxia Journal Article 2021 10.1186/s13054-021-03815-y Crit Care 25 440 1 https://www.ncbi.nlm.nih.gov/pubmed/34924022 M. Singer P. J. Young J. G. Laffey P. Asfar F. S. Taccone M. B. Skrifvars C. S. Meyhoff P. Radermacher article RN347 Experimental agents to improve fracture healing: utilizing the WNT signaling pathway Journal Article 2021 10.1016/j.injury.2020.11.051 Injury 52 S44-S48 http://www.sciencedirect.com/science/article/pii/S0020138320309773 Melanie Haffner-Luntzer article RN342 Ex vivo-expanded highly pure ABCB5(+) mesenchymal stromal cells as Good Manufacturing Practice-compliant autologous advanced therapy medicinal product for clinical use: process validation and first in-human data Journal Article 2021 10.1016/j.jcyt.2020.08.012 Cytotherapy 23 165-175 2 https://www.ncbi.nlm.nih.gov/pubmed/33011075 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8310651/pdf/nihms-1714686.pdf A. Kerstan E. Niebergall-Roth J. Esterlechner H. M. Schroder M. Gasser A. M. Waaga-Gasser M. Goebeler K. Rak P. Schrufer S. Endres P. Hagenbusch K. Kraft K. Dieter S. Ballikaya N. Stemler S. Sadeghi N. Tappenbeck G. F. Murphy D. P. Orgill N. Y. Frank C. Ganss K. Scharffetter-Kochanek M. H. Frank M. A. Kluth article RN371 Evaluation of the gut microbiome in association with biological signatures of inflammation in murine polytrauma and shock Journal Article 2021 10.1038/s41598-021-85897-w Sci Rep 11 6665 1 https://www.ncbi.nlm.nih.gov/pubmed/33758228 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7988149/pdf/41598_2021_Article_85897.pdf S. A. Appiah C. L. Foxx D. Langgartner A. Palmer C. A. Zambrano S. Braumuller E. J. Schaefer U. Wachter B. L. Elam P. Radermacher C. E. Stamper J. D. Heinze S. N. Salazar A. K. Luthens A. L. Arnold S. O. Reber M. Huber-Lang C. A. Lowry R. Halbgebauer article RN356 Effects of immune cells on mesenchymal stem cells during fracture healing Journal Article 2021 DOI: 10.4252/wjsc.v13.i11.1667 World J Stem Cells 13 1667-1695 11 Sabrina Ehnert Borna Relja K. Schmidt-Bleek Verena Fischer Anita Ignatius Caren Linnemann Helen Rinderknecht Markus Huber-Lang Miriam Kalbitz Tina Histing Andreas Nüssler article RN306 Effects of Acute Subdural Hematoma-Induced Brain Injury On Energy Metabolism in Peripheral Blood Mononuclear Cells Journal Article 2021 10.1097/SHK.0000000000001642 Shock 55 407-417 3 https://www.ncbi.nlm.nih.gov/pubmed/32826816 F. Zink J. Vogt U. Wachter J. Hartert M. Horchler X. Zhang F. Hezel T. Kapapa T. Datzmann A. Hoffmann M. Wepler E. Calzia P. Radermacher C. Hartmann article RN362 Early Results in Non-Displaced Femoral Neck Fractures Using the Femoral Neck System Journal Article 2021 10.1177/21514593211050153 Geriatr Orthop Surg Rehabil 12 21514593211050153 https://www.ncbi.nlm.nih.gov/pubmed/34733579 https://journals.sagepub.com/doi/pdf/10.1177/21514593211050153 R. Cintean C. Pankratz M. Hofmann F. Gebhard K. Schutze article RN320 Energetic dysfunction in sepsis: a narrative review Journal Article 2021 10.1186/s13613-021-00893-7 Ann Intensive Care 11 104 1 https://www.ncbi.nlm.nih.gov/pubmed/34216304 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8254847/pdf/13613_2021_Article_893.pdf S. Preau D. Vodovar B. Jung S. Lancel L. Zafrani A. Flatres M. Oualha G. Voiriot Y. Jouan J. Joffre F. Huel N. De Prost S. Silva E. Azabou P. Radermacher article RN309 Early myocardial damage (EMD) and valvular dysfunction after femur fracture in pigs Journal Article 2021 10.1038/s41598-021-86151-z Sci Rep 11 8503 1 https://www.ncbi.nlm.nih.gov/pubmed/33875675 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8055677/pdf/41598_2021_Article_86151.pdf B. Weber I. Lackner T. Miclau J. Stulz F. Gebhard R. Pfeifer P. Cinelli S. Halvachizadeh M. Teuben H. C. Pape M. Lipiski N. Cesarovic M. Kalbitz article RN314 DeltaMST and the Regulation of Cardiac CSE and OTR Expression in Trauma and Hemorrhage Journal Article 2021 10.3390/antiox10020233 Antioxidants (Basel) 10 233 2 https://www.ncbi.nlm.nih.gov/pubmed/33546491 https://mdpi-res.com/d_attachment/antioxidants/antioxidants-10-00233/article_deploy/antioxidants-10-00233-v2.pdf B. Trautwein T. Merz N. Denoix C. Szabo E. Calzia P. Radermacher O. McCook article RN369 Disruption of orbitofrontal-hypothalamic projections in a murine ALS model and in human patients Journal Article 2021 10.1186/s40035-021-00241-6 Transl Neurodegener 10 17 1 https://www.ncbi.nlm.nih.gov/pubmed/34059131 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8168014/pdf/40035_2021_Article_241.pdf D. Bayer S. Antonucci H. P. Muller R. Saad L. Dupuis V. Rasche T. M. Böckers A. C. Ludolph J. Kassubek F. Roselli article RN337 Differential effect of ethanol intoxication on peripheral markers of cerebral injury in murine blunt traumatic brain injury Journal Article 2021 10.1093/burnst/tkab027 Burns Trauma 9 tkab027 https://www.ncbi.nlm.nih.gov/pubmed/34604393 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8484207/pdf/tkab027.pdf Z. Li J. Zhang S. Halbgebauer A. Chandrasekar R. Rehman A. Ludolph T. Boeckers M. Huber-Lang M. Otto F. Roselli F. O. Heuvel article RN346 Differences in Fracture Healing Between Female and Male C57BL/6J Mice Journal Article 2021 10.3389/fphys.2021.712494 Front Physiol 12 1227 https://www.frontiersin.org/article/10.3389/fphys.2021.712494 Melanie Haffner-Luntzer Verena Fischer Anita Ignatius article RN324 Developmental impaired Akt signaling in the Shank1 and Shank3 double knock-out mice Journal Article 2021 10.1038/s41380-020-00979-x Molecular Psychiatry 26 1928–1944 ://WOS:000605147400001 https://www.nature.com/articles/s41380-020-00979-x.pdf A. Mossa J. Pagano L. Ponzoni A. Tozzi E. Vezzoli M. Sciaccaluga C. Costa S. Beretta M. Francolini M. Sala P. Calabresi T. M. Boeckers C. Sala C. Verpelli article RN292 Do medical students recognise the deteriorating patient by analysing their vital signs? A monocentric observational study based on the National Early Warning Score 2 Journal Article 2021 10.1136/bmjopen-2020-044354 BMJ Open 11 e044354 2 https://www.ncbi.nlm.nih.gov/pubmed/33622952 D. A. C. Messerer M. Fauler A. Horneffer A. Schneider O. Keis L. M. Mauder P. Radermacher article RN321 Deletion of Cdk5 in Macrophages Ameliorates Anti-Inflammatory Response during Endotoxemia through Induction of C-Maf and Il-10 Journal Article 2021 10.3390/ijms22179648 Int J Mol Sci 22 9648 17 https://www.ncbi.nlm.nih.gov/pubmed/34502552 https://mdpi-res.com/d_attachment/ijms/ijms-22-09648/article_deploy/ijms-22-09648-v2.pdf P. Pfänder A. K. Eiers U. Burret S. Vettorazzi article RN412 MSCs rescue impaired wound healing in a murine LAD1 model by adaptive responses to low TGF-beta1 levels Journal Article 2020 10.15252/embr.201949115 EMBO Rep 21 e49115 4 https://www.ncbi.nlm.nih.gov/pubmed/32080965 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7132342/pdf/EMBR-21-e49115.pdf D. Jiang K. Singh J. Muschhammer S. Schatz A. Sindrilaru E. Makrantonaki Y. Qi M. Wlaschek K. Scharffetter-Kochanek article RN385 Modified Candy-Package technique vs Cerclage technique for refixation of the lesser trochanteric fragment in pertrochanteric femoral fractures. A biomechanical comparison of 10 specimens Journal Article 2020 10.1016/j.injury.2020.06.008 Injury 51 1763-1768 8 https://www.ncbi.nlm.nih.gov/pubmed/32580889 C. Schopper M. Faschingbauer R. T. Moeller F. Gebhard L. Duerselen A. Seitz article RN403 Microcirculation vs. Mitochondria-What to Target? Journal Article 2020 10.3389/fmed.2020.00416 Front Med (Lausanne) 7 416 https://www.ncbi.nlm.nih.gov/pubmed/32903633 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7438707/pdf/fmed-07-00416.pdf T. Merz N. Denoix M. Huber-Lang M. Singer P. Radermacher O. McCook article RN374 Metabolic substrate utilization in stress-induced immune cells Journal Article 2020 10.1186/s40635-020-00316-0 Intensive Care Med Exp 8 28 Suppl 1 https://www.ncbi.nlm.nih.gov/pubmed/33336295 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7746792/pdf/40635_2020_Article_316.pdf X. Zhang F. Zink F. Hezel J. Vogt U. Wachter M. Wepler M. Loconte C. Kranz A. Hellmann B. Mizaikoff P. Radermacher C. Hartmann article RN413 Mesenchymal Stem Cells Adaptively Respond to Environmental Cues Thereby Improving Granulation Tissue Formation and Wound Healing Journal Article 2020 10.3389/fcell.2020.00697 Front Cell Dev Biol 8 697 https://www.ncbi.nlm.nih.gov/pubmed/32850818 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7403200/pdf/fcell-08-00697.pdf D. Jiang K. Scharffetter-Kochanek article RN414 Local and transient inhibition of p21 expression ameliorates age-related delayed wound healing Journal Article 2020 10.1111/wrr.12763 Wound Repair Regen 28 49-60 1 https://www.ncbi.nlm.nih.gov/pubmed/31571377 https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/wrr.12763?download=true D. Jiang J. C. Vries J. Muschhammer S. Schatz H. Ye T. Hein M. Fidan V. S. Romanov Y. Rinkevich K. Scharffetter-Kochanek article RN429 Mechanical stretch activates piezo1 in caveolae of alveolar type I cells to trigger ATP release and paracrine stimulation of surfactant secretion from alveolar type II cells Journal Article 2020 10.1096/fj.202000613RRR FASEB J 34 12785-12804 9 https://www.ncbi.nlm.nih.gov/pubmed/32744386 https://faseb.onlinelibrary.wiley.com/doi/pdfdirect/10.1096/fj.202000613RRR?download=true K. Diem M. Fauler G. Fois A. Hellmann N. Winokurow S. Schumacher C. Kranz M. Frick article RN378 Maternal Separation Induces Long-Term Alterations in the Cardiac Oxytocin Receptor and Cystathionine gamma-Lyase Expression in Mice Journal Article 2020 10.1155/2020/4309605 Oxid Med Cell Longev 2020 4309605 https://www.ncbi.nlm.nih.gov/pubmed/32082478 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7007946/pdf/OMCL2020-4309605.pdf D. C. Wigger N. Gröger A. Lesse S. Krause T. Merz H. Gundel K. Braun O. McCook P. Radermacher J. Böck C. Waller article RN399 Lipid metabolism adaptations are reduced in human compared to murine Schwann cells following injury Journal Article 2020 10.1038/s41467-020-15915-4 Nat Commun 11 2123 1 https://www.ncbi.nlm.nih.gov/pubmed/32358558 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7195462/pdf/41467_2020_Article_15915.pdf S. Meyer Zu Reckendorf C. Brand M. T. Pedro J. Hegler C. S. Schilling R. Lerner L. Bindila G. Antoniadis B. Knöll article RN383 Interference with SRF expression in skeletal muscles reduces peripheral nerve regeneration in mice Journal Article 2020 10.1038/s41598-020-62231-4 Sci Rep 10 5281 1 https://www.ncbi.nlm.nih.gov/pubmed/32210317 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7093445/pdf/41598_2020_Article_62231.pdf R. Wanner B. Knöll article RN397 NF-kappaB Signaling Negatively Regulates Osteoblast Dedifferentiation during Zebrafish Bone Regeneration Journal Article 2020 10.1016/j.devcel.2019.11.016 Dev Cell 52 167-182 e7 2 https://www.ncbi.nlm.nih.gov/pubmed/31866203 R. Mishra I. Sehring M. Cederlund M. Mulaw G. Weidinger article RN422 Interference of neuronal activity-mediated gene expression through serum response factor deletion enhances mortality and hyperactivity after traumatic brain injury Journal Article 2020 10.1096/fj.201902257RR FASEB J 34 3855-3873 3 https://www.ncbi.nlm.nih.gov/pubmed/31930559 https://faseb.onlinelibrary.wiley.com/doi/pdfdirect/10.1096/fj.201902257RR?download=true P. Forstner B. Knöll article RN390 Multiplexed chemogenetics in astrocytes and motoneurons restore blood-spinal cord barrier in ALS Journal Article 2020 10.26508/lsa.201900571 Life Sci Alliance 3 e201900571 11 https://www.ncbi.nlm.nih.gov/pubmed/32900826 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7479971/pdf/LSA-2019-00571.pdf N. Ouali Alami L. Tang D. Wiesner B. Commisso D. Bayer J. Weishaupt L. Dupuis P. Wong B. Baumann T. Wirth T. M. Boeckers D. Yilmazer-Hanke A. Ludolph F. Roselli article RN431 The Interaction of the Endogenous Hydrogen Sulfide and Oxytocin Systems in Fluid Regulation and the Cardiovascular System Journal Article 2020 10.3390/antiox9080748 Antioxidants (Basel) 9 748 8 https://www.ncbi.nlm.nih.gov/pubmed/32823845 https://mdpi-res.com/d_attachment/antioxidants/antioxidants-09-00748/article_deploy/antioxidants-09-00748.pdf N. Denoix O. McCook S. Ecker R. Wang C. Waller P. Radermacher T. Merz article RN377 P2 Purinergic Signaling in the Distal Lung in Health and Disease Journal Article 2020 10.3390/ijms21144973 Int J Mol Sci 21 4973 14 https://www.ncbi.nlm.nih.gov/pubmed/32674494 https://mdpi-res.com/d_attachment/ijms/ijms-21-04973/article_deploy/ijms-21-04973.pdf E. Wirsching M. Fauler G. Fois M. Frick article RN407 Reaming of femoral fractures with different reaming irrigator aspirator systems shows distinct effects on cardiac function after experimental polytrauma Journal Article 2020 10.1002/jor.24830 J Orthop Res 38 2608-2618 12 https://www.ncbi.nlm.nih.gov/pubmed/32827323 https://www.zora.uzh.ch/id/eprint/189334/1/111111111jor.24830.pdf I. Lackner B. Weber T. Miclau N. Holzwarth M. Baur F. Gebhard M. Teuben S. Halvachizadeh P. Cinelli R. Pfeifer M. Lipiski N. Cesarovic M. Haffner-Luntzer H. C. Pape M. Kalbitz Treat Research Group article RN384 Recent advancements in understanding fin regeneration in zebrafish Journal Article 2020 10.1002/wdev.367 Wiley Interdiscip Rev Dev Biol 9 e367 1 https://www.ncbi.nlm.nih.gov/pubmed/31726486 https://wires.onlinelibrary.wiley.com/doi/pdfdirect/10.1002/wdev.367?download=true I. M. Sehring G. Weidinger article RN386 Severe Traumatic Brain Injury (TBI) Modulates the Kinetic Profile of the Inflammatory Response of Markers for Neuronal Damage Journal Article 2020 10.3390/jcm9061667 J Clin Med 9 1667 6 https://www.ncbi.nlm.nih.gov/pubmed/32492963 https://mdpi-res.com/d_attachment/jcm/jcm-09-01667/article_deploy/jcm-09-01667.pdf C. R. Schindler T. Lustenberger M. Woschek P. Stormann D. Henrich P. Radermacher I. Marzi article RN433 Structural alterations and inflammation in the heart after multiple trauma followed by reamed versus non-reamed femoral nailing Journal Article 2020 10.1371/journal.pone.0235220 PLoS One 15 e0235220 6 https://www.ncbi.nlm.nih.gov/pubmed/32584885 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7316303/pdf/pone.0235220.pdf M. Baur B. Weber I. Lackner F. Gebhard R. Pfeifer P. Cinelli S. Halvachizadeh M. Teuben M. Lipiski N. Cesarovic H. C. Pape M. Kalbitz article RN425 Super-resolution microscopy unveils transmembrane domain-mediated internalization of cross-reacting material 197 into diphtheria toxin-resistant mouse J774A.1 cells and primary rat fibroblasts in vitro Journal Article 2020 10.1007/s00204-020-02731-4 Arch Toxicol 94 1753-1761 5 https://www.ncbi.nlm.nih.gov/pubmed/32266418 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7261736/pdf/204_2020_Article_2731.pdf M. Fellermann F. Wondany S. Carle J. Nemeth T. Sadhanasatish M. Frick H. Barth J. Michaelis article RN435 Synaptic restoration by cAMP/PKA drives activity-dependent neuroprotection to motoneurons in ALS Journal Article 2020 10.1084/jem.20191734 J Exp Med 217 e20191734 8 https://www.ncbi.nlm.nih.gov/pubmed/32484501 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7398175/pdf/JEM_20191734.pdf M. Baczyk N. O. Alami N. Delestree C. Martinot L. Tang B. Commisso D. Bayer N. Doisne W. Frankel M. Manuel F. Roselli D. Zytnicki article RN381 Systemic and Cardiac Alterations After Long Bone Fracture Journal Article 2020 10.1097/SHK.0000000000001536 Shock 54 761-773 6 https://www.ncbi.nlm.nih.gov/pubmed/32205793 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7664958/pdf/shk-54-761.pdf B. Weber I. Lackner D. Knecht C. K. Braun F. Gebhard M. Huber-Lang F. Hildebrand K. Horst H. C. Pape A. Ignatius H. Schrezenmeier M. Haffner-Luntzer M. Kalbitz article RN401 The Role of Glucocorticoid Receptor and Oxytocin Receptor in the Septic Heart in a Clinically Relevant, Resuscitated Porcine Model With Underlying Atherosclerosis Journal Article 2020 10.3389/fendo.2020.00299 Front Endocrinol (Lausanne) 11 299 https://www.ncbi.nlm.nih.gov/pubmed/32477273 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7239997/pdf/fendo-11-00299.pdf T. Merz N. Denoix D. Wigger C. Waller M. Wepler S. Vettorazzi J. Tuckermann P. Radermacher O. McCook article RN388 The Role of Mast Cells in Bone Metabolism and Bone Disorders Journal Article 2020 10.3389/fimmu.2020.00163 Front Immunol 11 163 https://www.frontiersin.org/article/10.3389/fimmu.2020.00163 Deniz Ragipoglu Anne Dudeck Melanie Haffner-Luntzer Martin Voss Jochen Kroner Anita Ignatius Verena Fischer article RN423 The role of physical trauma in social stress-induced immune activation Journal Article 2020 10.1016/j.neubiorev.2020.02.025 Neurosci Biobehav Rev 113 169-178 https://www.ncbi.nlm.nih.gov/pubmed/32109454 S. Foertsch S. O. Reber article RN418 Thirty-Eight-Negative Kinase 1 Is a Mediator of Acute Kidney Injury in Experimental and Clinical Traumatic Hemorrhagic Shock Journal Article 2020 10.3389/fimmu.2020.02081 Front Immunol 11 2081 https://www.ncbi.nlm.nih.gov/pubmed/32983160 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7479097/pdf/fimmu-11-02081.pdf R. Halbgebauer E. Karasu C. K. Braun A. Palmer S. Braumuller A. Schultze F. Schafer S. Buckle A. Eigner U. Wachter P. Radermacher R. R. G. Resuello J. V. Tuplano K. Nilsson Ekdahl B. Nilsson M. Armacki A. Kleger T. Seufferlein M. Kalbitz F. Gebhard J. D. Lambris M. Griensven M. Huber-Lang article RN393 TLR4-dependent shaping of the wound site by MSCs accelerates wound healing Journal Article 2020 10.15252/embr.201948777 EMBO Rep 21 e48777 5 https://www.ncbi.nlm.nih.gov/pubmed/32162777 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7202058/pdf/EMBR-21-e48777.pdf S. Munir A. Basu P. Maity L. Krug P. Haas D. Jiang G. Strauss M. Wlaschek H. Geiger K. Singh K. Scharffetter-Kochanek article RN409 Toll-Like Receptor-Mediated Cardiac Injury during Experimental Sepsis Journal Article 2020 10.1155/2020/6051983 Mediators Inflamm 2020 6051983 https://www.ncbi.nlm.nih.gov/pubmed/32410859 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7199613/pdf/MI2020-6051983.pdf I. Lackner B. Weber S. Chakraborty S. Braumuller M. Huber-Lang F. Gebhard M. Kalbitz article RN421 Influence of Obesity on the Organization of the Extracellular Matrix and Satellite Cell Functions After Combined Muscle and Thorax Trauma in C57BL/6J Mice Journal Article 2020 10.3389/fphys.2020.00849 Front Physiol 11 849 https://www.ncbi.nlm.nih.gov/pubmed/32848828 A. Gihring F. Gärtner C. Liu M. Hoenicka M. Wabitsch U. Knippschild P. Xu article RN392 Insights Into Development and Progression of Idiopathic Pulmonary Fibrosis From Single Cell RNA Studies Journal Article 2020 10.3389/fmed.2020.611728 Front Med (Lausanne) 7 611728 https://www.ncbi.nlm.nih.gov/pubmed/33392232 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7772461/pdf/fmed-07-611728.pdf J. Nemeth A. Schundner M. Frick article RN432 Effects of sodium thiosulfate (Na2S2O3) during resuscitation from hemorrhagic shock in swine with preexisting atherosclerosis Journal Article 2020 10.1016/j.phrs.2019.104536 Pharmacol Res 151 104536 https://www.ncbi.nlm.nih.gov/pubmed/31734346 T. Datzmann A. Hoffmann O. McCook T. Merz U. Wachter J. Preuss S. Vettorazzi E. Calzia M. Gröger F. Kohn A. Schmid N. Denoix P. Radermacher M. Wepler article RN375 Influence of obesity on remodeling of lung tissue and organization of extracellular matrix after blunt thorax trauma Journal Article 2020 10.1186/s12931-020-01502-0 Respir Res 21 238 1 https://www.ncbi.nlm.nih.gov/pubmed/32943048 P. Xu F. Gärtner A. Gihring C. Liu T. Burster M. Wabitsch U. Knippschild S. Paschke article RN434 Corticotropin-releasing hormone (CRH) alters mitochondrial morphology and function by activating the NF-kB-DRP1 axis in hippocampal neurons Journal Article 2020 10.1038/s41419-020-03204-3 Cell Death & Disease 11 19 11 ://WOS:000595866700002 https://www.nature.com/articles/s41419-020-03204-3.pdf C. R. Battaglia S. Cursano E. Calzia A. Catanese T. M. Boeckers article RN391 A Novel Fibroblast Reporter Cell Line for in vitro Studies of Pulmonary Fibrosis Journal Article 2020 10.3389/fphys.2020.567675 Front Physiol 11 567675 https://www.ncbi.nlm.nih.gov/pubmed/33162897 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7582034/pdf/fphys-11-567675.pdf J. Nemeth A. Schundner K. Quast V. E. Winkelmann M. Frick article RN419 A novel mouse model to study fracture healing of the proximal femur Journal Article 2020 10.1002/jor.24677 J Orthop Res 38 2131-2138 10 https://www.ncbi.nlm.nih.gov/pubmed/32232999 M. Haffner-Luntzer B. Weber C. Lam V. Fischer I. Lackner A. Ignatius M. Kalbitz R. S. Marcucio T. Miclau article RN424 Abdominal surgery prior to chronic psychosocial stress promotes spleen cell (re)activity and glucocorticoid resistance Journal Article 2020 10.1038/s41598-020-63419-4 Sci Rep 10 6917 1 https://www.ncbi.nlm.nih.gov/pubmed/32332802 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7181742/pdf/41598_2020_Article_63419.pdf S. Foertsch D. Langgartner S. O. Reber article RN398 Actin and Myosin in Non-Neuronal Exocytosis Journal Article 2020 10.3390/cells9061455 Cells 9 1455 6 https://www.ncbi.nlm.nih.gov/pubmed/32545391 https://mdpi-res.com/d_attachment/cells/cells-09-01455/article_deploy/cells-09-01455-v2.pdf P. Miklavc M. Frick article RN415 Animal models to study metaphyseal bone fracture healing Journal Article 2020 10.22203/eCM.v040a11 Eur Cell Mater 40 172-188 A. Ignatius M. Haffner-Luntzer article RN405 Inflammation, Thrombosis, and Destruction: The Three-Headed Cerberus of Trauma- and SARS-CoV-2-Induced ARDS Journal Article 2020 10.3389/fimmu.2020.584514 Front Immunol 11 584514 https://www.ncbi.nlm.nih.gov/pubmed/33101314 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7546394/pdf/fimmu-11-584514.pdf L. Lupu A. Palmer M. Huber-Lang article RN404 Autism-associated SHANK3 mutations impair maturation of neuromuscular junctions and striated muscles Journal Article 2020 10.1126/scitranslmed.aaz3267 Sci Transl Med 12 eaaz3267 547 https://www.ncbi.nlm.nih.gov/pubmed/32522805 https://www.science.org/doi/10.1126/scitranslmed.aaz3267 A. K. Lutz S. Pfaender B. Incearap V. Ioannidis I. Ottonelli K. J. Fohr J. Cammerer M. Zoller J. Higelin F. Giona M. Stetter N. Stoecker N. O. Alami M. Schon M. Orth S. Liebau G. Barbi A. M. Grabrucker R. Delorme M. Fauler B. Mayer S. Jesse F. Roselli A. C. Ludolph T. Bourgeron C. Verpelli M. Demestre T. M. Boeckers article RN408 Cardiac Glucose and Fatty Acid Transport After Experimental Mono- and Polytrauma Journal Article 2020 10.1097/SHK.0000000000001400 Shock 53 620-629 5 https://www.ncbi.nlm.nih.gov/pubmed/31313740 https://www.zora.uzh.ch/id/eprint/172261/1/2019_Lackner_Shock_Cardiac_Glucose_and_Fatty_Acid.pdf I. Lackner B. Weber D. Knecht K. Horst B. Relja F. Gebhard H. C. Pape M. Huber-Lang F. Hildebrand M. Kalbitz Treat Research Group article RN430 Cerebral Immunohistochemical Characterization of the H2S and the Oxytocin Systems in a Porcine Model of Acute Subdural Hematoma Journal Article 2020 10.3389/fneur.2020.00649 Front Neurol 11 649 https://www.ncbi.nlm.nih.gov/pubmed/32754111 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7358568/pdf/fneur-11-00649.pdf N. Denoix T. Merz S. Unmuth A. Hoffmann E. Nespoli A. Scheuerle M. Huber-Lang H. Gundel C. Waller P. Radermacher O. McCook article RN426 Clostridial C3 Toxins Enter and Intoxicate Human Dendritic Cells Journal Article 2020 10.3390/toxins12090563 Toxins (Basel) 12 563 9 https://www.ncbi.nlm.nih.gov/pubmed/32883045 https://mdpi-res.com/d_attachment/toxins/toxins-12-00563/article_deploy/toxins-12-00563.pdf M. Fellermann C. Huchler L. Fechter T. Kolb F. Wondany D. Mayer J. Michaelis S. Stenger K. Mellert P. Möller T. F. E. Barth S. Fischer H. Barth article RN410 Complement Activation and Organ Damage After Trauma-Differential Immune Response Based on Surgical Treatment Strategy Journal Article 2020 10.3389/fimmu.2020.00064 Front Immunol 11 64 https://www.ncbi.nlm.nih.gov/pubmed/32117238 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7025487/pdf/fimmu-11-00064.pdf I. Lackner B. Weber M. Baur G. Fois F. Gebhard R. Pfeifer P. Cinelli S. Halvachizadeh M. Lipiski N. Cesarovic H. Schrezenmeier M. Huber-Lang H. C. Pape M. Kalbitz article RN411 Complement C5a Induces Pro-inflammatory Microvesicle Shedding in Severely Injured Patients Journal Article 2020 10.3389/fimmu.2020.01789 Front Immunol 11 1789 https://www.ncbi.nlm.nih.gov/pubmed/32983087 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7492592/pdf/fimmu-11-01789.pdf E. Karasu J. Demmelmaier S. Kellermann K. Holzmann J. Kohl C. Q. Schmidt M. Kalbitz F. Gebhard M. S. Huber-Lang R. Halbgebauer article RN396 Complement in sepsis-when science meets clinics Journal Article 2020 10.1002/1873-3468.13881 FEBS Lett 594 2621-2632 16 https://www.ncbi.nlm.nih.gov/pubmed/32621378 https://febs.onlinelibrary.wiley.com/doi/pdfdirect/10.1002/1873-3468.13881?download=true T. E. Mollnes M. Huber-Lang article RN400 Animal-Free Human Whole Blood Sepsis Model to Study Changes in Innate Immunity Journal Article 2020 10.3389/fimmu.2020.571992 Front Immunol 11 571992 https://www.ncbi.nlm.nih.gov/pubmed/33178198 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7592114/pdf/fimmu-11-571992.pdf D. A. C. Messerer L. Vidoni M. Erber A. E. P. Stratmann J. M. Bauer C. K. Braun S. Hug A. Adler K. Nilsson Ekdahl B. Nilsson E. Barth P. Radermacher M. Huber-Lang article RN387 Crucial role of the terminal complement complex in chondrocyte death and hypertrophy after cartilage trauma Journal Article 2020 10.1016/j.joca.2020.01.004 Osteoarthritis Cartilage 28 685-697 5 https://www.ncbi.nlm.nih.gov/pubmed/31981738 J. Riegger M. Huber-Lang R. E. Brenner article RN376 Ethanol Intoxication Alleviates the Inflammatory Response of Remote Organs to Experimental Traumatic Brain Injury Journal Article 2020 10.3390/ijms21218181 Int J Mol Sci 21 8181 21 https://www.ncbi.nlm.nih.gov/pubmed/33142949 https://mdpi-res.com/d_attachment/ijms/ijms-21-08181/article_deploy/ijms-21-08181-v2.pdf B. Xu A. Chandrasekar F. Olde Heuvel M. Powerski A. Nowak L. Noack J. Omari M. Huber-Lang F. Roselli B. Relja article RN394 Diffusion Tensor Imaging-Based Studies at the Group-Level Applied to Animal Models of Neurodegenerative Diseases Journal Article 2020 10.3389/fnins.2020.00734 Front Neurosci 14 734 https://www.ncbi.nlm.nih.gov/pubmed/32982659 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7487414/pdf/fnins-14-00734.pdf H. P. Muller F. Roselli V. Rasche J. Kassubek article RN379 Impact of downstream effects of glucocorticoid receptor dysfunction on organ function in critical illness-associated systemic inflammation Journal Article 2020 10.1186/s40635-020-00325-z Intensive Care Med Exp 8 37 Suppl 1 https://www.ncbi.nlm.nih.gov/pubmed/33336296 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7746781/pdf/40635_2020_Article_325.pdf M. Wepler J. M. Preuss T. Merz O. McCook P. Radermacher J. P. Tuckermann S. Vettorazzi article RN402 H2S in acute lung injury: a therapeutic dead end(?) Journal Article 2020 10.1186/s40635-020-00324-0 Intensive Care Med Exp 8 33 Suppl 1 https://www.ncbi.nlm.nih.gov/pubmed/33336306 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7746418/pdf/40635_2020_Article_324.pdf T. Merz N. Denoix M. Wepler H. Gassler D. A. C. Messerer C. Hartmann T. Datzmann P. Radermacher O. McCook article RN417 Functional immune monitoring in severely injured patients-A pilot study Journal Article 2020 10.1111/sji.12837 Scand J Immunol 91 e12837 2 https://www.ncbi.nlm.nih.gov/pubmed/31622512 https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/sji.12837?download=true R. Halbgebauer S. Kellermann F. Schafer S. Weckbach M. Weiss E. Barth H. Bracht M. Kalbitz F. Gebhard M. S. Huber-Lang M. Perl article RN395 Focal alterations of the callosal area III in primary lateral sclerosis: An MRI planimetry and texture analysis Journal Article 2020 10.1016/j.nicl.2020.102223 Neuroimage Clin 26 102223 https://www.ncbi.nlm.nih.gov/pubmed/32114375 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7049663/pdf/main.pdf H. P. Muller J. Dreyhaupt F. Roselli M. Schlecht A. C. Ludolph H. J. Huppertz J. Kassubek article RN372 Geriatric patients with dementia show increased mortality and lack of functional recovery after hip fracture treated with hemiprosthesis Journal Article 2020 10.1007/s00068-020-01472-4 Eur J Trauma Emerg Surg https://www.ncbi.nlm.nih.gov/pubmed/32865595 K. Schuetze A. Eickhoff K. S. Rutetzki P. H. Richter F. Gebhard C. Ehrnthaller article RN416 Electrocatalytically modified microelectrodes for the detection of hydrogen peroxide at blood cells from swine with induced trauma Journal Article 2020 https://doi.org/10.1016/j.electacta.2020.136458 Electrochimica Acta 353 136458 https://www.sciencedirect.com/science/article/pii/S0013468620308513 A. Hellmann S. Daboss F. Zink C. Hartmann P. Radermacher C. Kranz article RN382 Effects of Circulating HMGB-1 and Histones on Cardiomyocytes-Hemadsorption of These DAMPs as Therapeutic Strategy after Multiple Trauma Journal Article 2020 10.3390/jcm9051421 J Clin Med 9 1421 5 https://www.ncbi.nlm.nih.gov/pubmed/32403440 https://mdpi-res.com/d_attachment/jcm/jcm-09-01421/article_deploy/jcm-09-01421.pdf B. Weber I. Lackner M. Baur G. Fois F. Gebhard I. Marzi H. Schrezenmeier B. Relja M. Kalbitz article RN406 Effect of High-Caloric Nutrition on Survival in Amyotrophic Lateral Sclerosis Journal Article 2020 10.1002/ana.25661 Ann Neurol 87 206-216 2 https://www.ncbi.nlm.nih.gov/pubmed/31849093 https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/ana.25661?download=true A. C. Ludolph J. Dorst J. Dreyhaupt J. H. Weishaupt J. Kassubek U. Weiland T. Meyer S. Petri A. Hermann A. Emmer J. Grosskreutz T. Grehl D. Zeller M. Boentert B. Schrank J. Prudlo A. S. Winkler S. Gorbulev F. Roselli J. Schuster L. Dupuis Lipcal-Als Study Group article RN428 Effect of high-caloric nutrition on serum neurofilament light chain levels in amyotrophic lateral sclerosis Journal Article 2020 10.1136/jnnp-2020-323372 J Neurol Neurosurg Psychiatry 91 1007-1009 9 https://www.ncbi.nlm.nih.gov/pubmed/32788256 https://jnnp.bmj.com/content/jnnp/91/9/1007.full.pdf J. Dorst J. Schuster J. Dreyhaupt S. Witzel J. H. Weishaupt J. Kassubek U. Weiland S. Petri T. Meyer T. Grehl A. Hermann B. Jordan J. Grosskreutz D. Zeller M. Boentert B. Schrank J. Prudlo A. S. Winkler S. Gorbulev F. Roselli L. Dupuis M. Otto A. C. Ludolph article RN389 Editorial: Translational Insights Into Mechanisms and Therapy of Organ Dysfunction in Sepsis and Trauma Journal Article 2020 10.3389/fimmu.2020.01987 Front Immunol 11 1987 https://www.ncbi.nlm.nih.gov/pubmed/33101267 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7546816/pdf/fimmu-11-01987.pdf P. Radermacher T. R. Billiar P. Ghezzi L. Martin C. Thiemermann article RN427 Editorial: Shankopathies: Shank Protein Deficiency-Induced Synaptic Diseases Journal Article 2020 10.3389/fnmol.2020.00011 Frontiers in Molecular Neuroscience 13 2 ://WOS:000517314300001 E. Ey T. Bourgeron T. M. Boeckers E. Kim K. Han article RN420 Early efficacy evaluation of mesenchymal stromal cells (MSC) combined to biomaterials to treat long bone non-unions Journal Article 2020 10.1016/j.injury.2020.02.070 Injury 51 Suppl 1 S63-S73 https://www.ncbi.nlm.nih.gov/pubmed/32139130 E. Gomez-Barrena N. Padilla-Eguiluz P. Rosset F. Gebhard P. Hernigou N. Baldini H. Rouard L. Sensebe R. M. Gonzalo-Daganzo R. Giordano E. Garcia-Rey J. Cordero-Ampuero J. C. Rubio-Suarez M. D. Garcia-Simon J. Stanovici C. Ehrnthaller M. Huber-Lang C. H. Flouzat-Lachaniette N. Chevallier D. M. Donati B. Spazzoli G. Ciapetti S. Fleury M. N. Fernandez J. R. Cabrera C. Avendano-Sola T. Montemurro C. Panaitescu E. Veronesi M. T. Rojewski R. Lotfi M. Dominici H. Schrezenmeier P. Layrolle article RN470 Sensory contact to the stressor prevents recovery from structural and functional heart damage following psychosocial trauma Journal Article 2019 10.1016/j.bbi.2019.05.013 Brain Behav Immun 80 667-677 https://www.ncbi.nlm.nih.gov/pubmed/31085218 S. Foertsch I. Lackner B. Weber A. M. Fuchsl D. Langgartner E. Wirkert S. Peters G. Fois J. Pressmar J. M. Fegert M. Frick H. Gundel M. Kalbitz S. O. Reber article RN445 Newly defined ABCB5(+) dermal mesenchymal stem cells promote healing of chronic iron overload wounds via secretion of interleukin-1 receptor antagonist Journal Article 2019 10.1002/stem.3022 Stem Cells 37 1057-1074 8 https://www.ncbi.nlm.nih.gov/pubmed/31002437 S. Vander Beken J. C. Vries B. Meier-Schiesser P. Meyer D. Jiang A. Sindrilaru F. F. Ferreira A. Hainzl S. Schatz J. Muschhammer N. J. Scheurmann P. Kampilafkos A. M. Seitz L. Dürselen A. Ignatius M. A. Kluth C. Ganss M. Wlaschek K. Singh P. Maity N. Y. Frank M. H. Frank K. Scharffetter-Kochanek article RN448 Osteoporotic Bone: When and How to Use Augmentation? Journal Article 2019 10.1097/BOT.0000000000001643 J Orthop Trauma 33 Suppl 8 S21-S26 https://www.ncbi.nlm.nih.gov/pubmed/31688523 K. Schuetze A. Eickhoff G. Röderer F. Gebhard P. H. Richter article RN461 Part III: Minimum Quality Threshold in Preclinical Sepsis Studies (MQTiPSS) for Fluid Resuscitation and Antimicrobial Therapy Endpoints Journal Article 2019 10.1097/SHK.0000000000001209 Shock 51 33-43 1 https://www.ncbi.nlm.nih.gov/pubmed/29923896 J. Hellman S. Bahrami M. Boros I. H. Chaudry G. Fritsch W. Gozdzik S. Inoue P. Radermacher M. Singer M. F. Osuchowski M. Huber-Lang article RN474 Parvalbumin Interneurons Shape Neuronal Vulnerability in Blunt TBI Journal Article 2019 10.1093/cercor/bhy139 Cereb Cortex 29 2701-2715 6 https://www.ncbi.nlm.nih.gov/pubmed/29982364 https://watermark.silverchair.com/bhy139.pdf?token=AQECAHi208BE49Ooan9kkhW_Ercy7Dm3ZL_9Cf3qfKAc485ysgAAAuIwggLeBgkqhkiG9w0BBwagggLPMIICywIBADCCAsQGCSqGSIb3DQEHATAeBglghkgBZQMEAS4wEQQMkYeSXmWjjC7a_ciTAgEQgIIClV A. Chandrasekar F. O. Heuvel L. Tar A. M. Hagenston A. Palmer B. Linkus A. C. Ludolph M. Huber-Lang T. Boeckers H. Bading F. Roselli article RN467 Preclinical septic shock research: why we need an animal ICU Journal Article 2019 10.1186/s13613-019-0543-6 Ann Intensive Care 9 66 1 https://www.ncbi.nlm.nih.gov/pubmed/31183570 https://hal.archives-ouvertes.fr/hal-02153561/document A. Guillon S. Preau J. Aboab E. Azabou B. Jung S. Silva J. Textoris F. Uhel D. Vodovar L. Zafrani N. Prost P. Radermacher Society French Intensive Care article RN456 Reduced Terminal Complement Complex Formation in Mice Manifests in Low Bone Mass and Impaired Fracture Healing Journal Article 2019 10.1016/j.ajpath.2018.09.011 Am J Pathol 189 147-161 1 https://www.ncbi.nlm.nih.gov/pubmed/30339839 Y. Mödinger A. E. Rapp A. Vikman Z. Ren V. Fischer S. Bergdolt M. Haffner-Luntzer W. C. Song J. D. Lambris M. Huber-Lang C. Neidlinger-Wilke R. Brenner A. Ignatius article RN436 Remote Intestinal Injury Early After Experimental Polytrauma and Hemorrhagic Shock Journal Article 2019 10.1097/SHK.0000000000001271 Shock 52 e45-e51 4 https://www.ncbi.nlm.nih.gov/pubmed/30289852 L. Wrba J. J. Ohmann P. Eisele S. Chakraborty S. Braumuller C. K. Braun B. Klohs A. Schultze H. Baum A. Palmer M. Huber-Lang R. Halbgebauer article RN475 Retinoic acid worsens ATG10-dependent autophagy impairment in TBK1-mutant hiPSC-derived motoneurons through SQSTM1/p62 accumulation Journal Article 2019 10.1080/15548627.2019.1589257 Autophagy 15 1719-1737 10 https://www.ncbi.nlm.nih.gov/pubmed/30939964 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6735587/pdf/kaup-15-10-1589257.pdf A. Catanese F. Olde Heuvel M. Mulaw M. Demestre J. Higelin G. Barbi A. Freischmidt J. H. Weishaupt A. C. Ludolph F. Roselli T. M. Boeckers article RN443 Three-Dimensional In vivo Magnetic Resonance Imaging (MRI) of Mouse Facial Nerve Regeneration Journal Article 2019 10.3389/fneur.2019.00310 Front Neurol 10 310 https://www.ncbi.nlm.nih.gov/pubmed/31001195 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454117/pdf/fneur-10-00310.pdf R. Wanner A. Abaei V. Rasche B. Knöll article RN450 Sequence-Optimized Peptide Nanofibers as Growth Stimulators for Regeneration of Peripheral Neurons Journal Article 2019 https://doi.org/10.1002/adfm.201809112 Advanced Functional Materials 29 1809112 24 ://WOS:000471074000025 C. Schilling T. Mack S. Lickfett S. Sieste F. S. Ruggeri T. Sneideris A. Dutta T. Bereau R. Naraghi D. Sinske T. P. J. Knowles C. V. Synatschke T. Weil B. Knöll article RN460 Single-cell analysis uncovers that metabolic reprogramming by ErbB2 signaling is essential for cardiomyocyte proliferation in the regenerating heart Journal Article 2019 10.7554/eLife.50163 Elife 8 https://www.ncbi.nlm.nih.gov/pubmed/31868166 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7000220/pdf/elife-50163.pdf H. Honkoop D. E. Bakker A. Aharonov F. Kruse A. Shakked P. D. Nguyen C. Heus L. Garric M. J. Muraro A. Shoffner F. Tessadori J. C. Peterson W. Noort A. Bertozzi G. Weidinger G. Posthuma D. Grun W. J. Laarse J. Klumperman R. T. Jaspers K. D. Poss A. Oudenaarden E. Tzahor J. Bakkers article RN453 STAT6 mediates the effect of ethanol on neuroinflammatory response in TBI Journal Article 2019 10.1016/j.bbi.2019.06.019 Brain Behav Immun 81 228-246 https://www.ncbi.nlm.nih.gov/pubmed/31207335 F. Olde Heuvel S. Holl A. Chandrasekar Z. Li Y. Wang R. Rehman P. Forstner D. Sinske A. Palmer D. Wiesner A. Ludolph M. Huber-Lang B. Relja T. Wirth T. Röszer B. Baumann T. Boeckers B. Knöll F. Roselli article RN462 Supramolecular Toxin Complexes for Targeted Pharmacological Modulation of Polymorphonuclear Leukocyte Functions Journal Article 2019 10.1002/adhm.201900665 Adv Healthc Mater 8 e1900665 17 https://www.ncbi.nlm.nih.gov/pubmed/31318180 https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/adhm.201900665?download=true A. J. Heck T. Ostertag L. Schnell S. Fischer B. K. Agrawalla P. Winterwerber E. Wirsching M. Fauler M. Frick S. L. Kuan T. Weil H. Barth article RN459 Targeting Complement Pathways in Polytrauma- and Sepsis-Induced Multiple-Organ Dysfunction Journal Article 2019 10.3389/fimmu.2019.00543 Front Immunol 10 543 https://www.ncbi.nlm.nih.gov/pubmed/30949180 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437067/pdf/fimmu-10-00543.pdf E. Karasu B. Nilsson J. Kohl J. D. Lambris M. Huber-Lang article RN468 The Effects of Genetic 3-Mercaptopyruvate Sulfurtransferase Deficiency in Murine Traumatic-Hemorrhagic Shock Journal Article 2019 10.1097/SHK.0000000000001165 Shock 51 472-478 4 https://www.ncbi.nlm.nih.gov/pubmed/29668565 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6192867/pdf/nihms959306.pdf M. Gröger M. Wepler U. Wachter T. Merz O. McCook S. Kress B. Lukaschewski S. Häfner M. Huber-Lang E. Calzia M. Georgieff N. Nagahara C. Szabo P. Radermacher C. Hartmann article RN439 The Mitochondria-Targeted H2S-Donor AP39 in a Murine Model of Combined Hemorrhagic Shock and Blunt Chest Trauma Journal Article 2019 10.1097/SHK.0000000000001210 Shock 52 230-239 2 https://www.ncbi.nlm.nih.gov/pubmed/29927788 M. Wepler T. Merz U. Wachter J. Vogt E. Calzia A. Scheuerle P. Möller M. Gröger S. Kress M. Fink B. Lukaschewski G. Rumm B. Stahl M. Georgieff M. Huber-Lang R. Torregrossa M. Whiteman O. McCook P. Radermacher C. Hartmann article RN457 Midkine Is Elevated After Multiple Trauma and Acts Directly on Human Cardiomyocytes by Altering Their Functionality and Metabolism Journal Article 2019 10.3389/fimmu.2019.01920 Front Immunol 10 1920 https://www.ncbi.nlm.nih.gov/pubmed/31552013 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6736577/pdf/fimmu-10-01920.pdf I. Lackner B. Weber M. Baur M. Haffner-Luntzer T. Eiseler G. Fois F. Gebhard B. Relja I. Marzi R. Pfeifer S. Halvachizadeh M. Lipiski N. Cesarovic H. C. Pape M. Kalbitz Treat Research Group article RN451 TREM1-ors shake the brain and gut after stroke Journal Article 2019 10.1038/s41590-019-0443-9 Nat Immunol 20 950-952 8 https://www.ncbi.nlm.nih.gov/pubmed/31285627 https://www.nature.com/articles/s41590-019-0443-9.pdf F. Roselli M. Huber-Lang article RN442 Modeling trauma in rats: similarities to humans and potential pitfalls to consider Journal Article 2019 10.1186/s12967-019-2052-7 J Transl Med 17 305 1 https://doi.org/10.1186/s12967-019-2052-7 Birte Weber Ina Lackner Melanie Haffner-Luntzer Annette Palmer Jochen Pressmar Karin Scharffetter-Kochanek Bernd Knöll Hubert Schrezenmeier Borna Relja Miriam Kalbitz article RN441 Tissue damage in the heart after cardiac arrest induced by asphyxia and hemorrhage in newborn pigs Journal Article 2019 10.1038/s41390-019-0505-6 Pediatr Res 86 709-718 6 https://www.ncbi.nlm.nih.gov/pubmed/31336381 B. Weber M. R. Mendler I. Lackner J. Pressmar M. Haffner-Luntzer S. Hofler C.K. Braun H. Hummler S. Schwarz M. Kalbitz article RN440 Lung injury after asphyxia and hemorrhagic shock in newborn piglets: Analysis of structural and inflammatory changes Journal Article 2019 10.1371/journal.pone.0219211 Plos One 14 14 7 ://WOS:000484936300051 https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0219211&type=printable B. Weber M. R. Mendler I. Lackner A. Zelewski S. Hofler M. Baur C. K. Braun H. Hummler S. Schwarz J. Pressmar M. Kalbitz article RN471 Fighting the Fire: Mechanisms of Inflammatory Gene Regulation by the Glucocorticoid Receptor Journal Article 2019 10.3389/fimmu.2019.01859 Front Immunol 10 1859 https://www.ncbi.nlm.nih.gov/pubmed/31440248 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6693390/pdf/fimmu-10-01859.pdf L. Escoter-Torres G. Caratti A. Mechtidou J. Tuckermann N. H. Uhlenhaut S. Vettorazzi article RN455 Longitudinal diffusion tensor magnetic resonance imaging analysis at the cohort level reveals disturbed cortical and callosal microstructure with spared corticospinal tract in the TDP-43 (G298S) ALS mouse model Journal Article 2019 10.1186/s40035-019-0163-y Transl Neurodegener 8 27 https://www.ncbi.nlm.nih.gov/pubmed/31485326 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6716821/pdf/40035_2019_Article_163.pdf H. P. Muller D. Brenner F. Roselli D. Wiesner A. Abaei M. Gorges K. M. Danzer A. C. Ludolph W. Tsao P. C. Wong V. Rasche J. H. Weishaupt J. Kassubek article RN465 A Review of Animal Models of Comorbidities in Fracture-Healing Research Journal Article 2019 10.1002/jor.24454 J Orthop Res 37 2491-2498 12 https://www.ncbi.nlm.nih.gov/pubmed/31444806 M. Haffner-Luntzer K. D. Hankenson A. Ignatius R. Pfeifer B. A. Khader F. Hildebrand M. Griensven H. C. Pape M. Lehmicke article RN454 Age-Related Gliosis Promotes Central Nervous System Lymphoma through CCL19-Mediated Tumor Cell Retention Journal Article 2019 10.1016/j.ccell.2019.08.001 Cancer Cell 36 250-267 e9 3 https://www.ncbi.nlm.nih.gov/pubmed/31526758 T. O'Connor X. Zhou J. Kosla A. Adili M. Garcia Beccaria E. Kotsiliti D. Pfister A. L. Johlke A. Sinha R. Sankowski M. Schick R. Lewis N. Dokalis B. Seubert B. Hochst D. Inverso D. Heide W. Zhang P. Weihrich K. Manske D. Wohlleber M. Anton A. Hoellein G. Seleznik J. Bremer S. Bleul H. G. Augustin F. Scherer U. Koedel A. Weber U. Protzer R. Förster T. Wirth A. Aguzzi F. Meissner M. Prinz B. Baumann U. E. Hopken P. A. Knolle L. Baumgarten U. Keller M. Heikenwalder article RN473 Cardiac Effects of Hyperoxia During Resuscitation From Hemorrhagic Shock in Swine Journal Article 2019 10.1097/SHK.0000000000001283 Shock 52 e52-e59 4 https://www.ncbi.nlm.nih.gov/pubmed/30407373 T. Datzmann M. Wepler U. Wachter J. A. Vogt O. McCook T. Merz E. Calzia M. Gröger C. Hartmann P. Asfar P. Radermacher B. L. Nussbaum article RN463 Challenge to the Intestinal Mucosa During Sepsis Journal Article 2019 10.3389/fimmu.2019.00891 Front Immunol 10 891 https://www.ncbi.nlm.nih.gov/pubmed/31114571 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6502990/pdf/fimmu-10-00891.pdf F. Haussner S. Chakraborty R. Halbgebauer M. Huber-Lang article RN466 Chronic psychosocial stress compromises the immune response and endochondral ossification during bone fracture healing via β-AR signaling Journal Article 2019 10.1073/pnas.1819218116 Proc Natl Acad Sci U S A 116 8615-8622 117 Melanie Haffner-Luntzer Sandra Foertsch Verena Fischer Katja Prystaz Miriam Tschaffon Yvonne Mödinger Chelsea S. Bahney Ralph S. Marcucio Theodore Miclau Anita Ignatius Stefan O. Reber article RN444 Distinct Dynamics of Stem and Progenitor Cells in Blood of Polytraumatized Patients Journal Article 2019 10.1097/SHK.0000000000001198 Shock 51 430-438 4 https://www.ncbi.nlm.nih.gov/pubmed/30289853 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6407807/pdf/shk-51-430.pdf M. Vogel H. Christow I. Manz M. Denkinger A. Amoah D. Schutz A. Brown B. Mohrle A. Schaffer M. Kalbitz F. Gebhard B. Mayer M. Huber-Lang H. Geiger article RN544 Effects of Psychosocial Stress on Subsequent Hemorrhagic Shock and Resuscitation in Male Mice Journal Article 2019 10.1097/SHK.0000000000001204 Shock 51 725-730 6 https://www.ncbi.nlm.nih.gov/pubmed/29889818 D. Langgartner U. Wachter C. Hartmann M. Gröger J. Vogt T. Merz O. McCook M. Fink S. Kress M. Georgieff J. F. Kunze P. L. Radermacher S. O. Reber M. Wepler article RN452 Cdk5 Deletion Enhances the Anti-inflammatory Potential of GC-Mediated GR Activation During Inflammation Journal Article 2019 10.3389/fimmu.2019.01554 Front Immunol 10 1554 https://www.ncbi.nlm.nih.gov/pubmed/31354714 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6635475/pdf/fimmu-10-01554.pdf P. Pfänder M. Fidan U. Burret L. Lipinski S. Vettorazzi article RN446 Identification of mineralocorticoid receptor target genes in the mouse hippocampus Journal Article 2019 10.1111/jne.12735 J Neuroendocrinol 31 e12735 8 https://www.ncbi.nlm.nih.gov/pubmed/31121060 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6771480/pdf/JNE-31-na.pdf Ltcm Weert J. C. Buurstede H. C. M. Sips S. Vettorazzi I. M. Mol J. Hartmann S. Prekovic W. Zwart M. V. Schmidt B. Roozendaal J. P. Tuckermann R. A. Sarabdjitsingh O. C. Meijer article RN449 Impact of oral anticoagulation on proximal femur fractures treated within 24 h - A retrospective chart review Journal Article 2019 10.1016/j.injury.2019.09.011 Injury 50 2040-2044 11 https://www.ncbi.nlm.nih.gov/pubmed/31543315 K. Schuetze A. Eickhoff C. Dehner F. Gebhard P. H. Richter article RN545 Impaired Glucocorticoid Receptor Dimerization Aggravates LPS-Induced Circulatory and Pulmonary Dysfunction Journal Article 2019 10.3389/fimmu.2019.03152 Front Immunol 10 3152 https://www.ncbi.nlm.nih.gov/pubmed/32038649 M. Wepler J. M. Preuss T. Merz C. Hartmann U. Wachter O. McCook J. Vogt S. Kress M. Gröger M. Fink A. Scheuerle P. Möller E. Calzia U. Burret P. Radermacher J. P. Tuckermann S. Vettorazzi article RN447 In vivo safety profile and biodistribution of GMP-manufactured human skin-derived ABCB5-positive mesenchymal stromal cells for use in clinical trials Journal Article 2019 10.1016/j.jcyt.2018.12.005 Cytotherapy 21 546-560 5 https://www.ncbi.nlm.nih.gov/pubmed/30878384 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6513723/pdf/nihms-1027450.pdf N. Tappenbeck H. M. Schroder E. Niebergall-Roth F. Hassinger U. Dehio K. Dieter K. Kraft A. Kerstan J. Esterlechner N. Y. Frank K. Scharffetter-Kochanek G. F. Murphy D. P. Orgill J. Beck M. H. Frank C. Ganss M. A. Kluth article RN464 In-Depth Characterization of the Effects of Cigarette Smoke Exposure on the Acute Trauma Response and Hemorrhage in Mice Journal Article 2019 10.1097/SHK.0000000000001115 Shock 51 68-77 1 https://www.ncbi.nlm.nih.gov/pubmed/29424792 C. Hartmann M. Gröger J. P. Noirhomme A. Scheuerle P. Möller U. Wachter M. Huber-Lang B. Nussbaum B. Jung T. Merz O. McCook S. Kress B. Stahl E. Calzia M. Georgieff P. Radermacher M. Wepler article RN438 Inflammation-induced upregulation of P2X4 expression augments mucin secretion in airway epithelia Journal Article 2019 10.1152/ajplung.00157.2018 Am J Physiol Lung Cell Mol Physiol 316 L58-L70 1 https://www.ncbi.nlm.nih.gov/pubmed/30358443 https://journals.physiology.org/doi/pdf/10.1152/ajplung.00157.2018 V. E. Winkelmann K. E. Thompson K. Neuland A. M. Jaramillo G. Fois H. Schmidt O. H. Wittekindt W. Han M. J. Tuvim B. F. Dickey P. Dietl M. Frick article RN476 Inflammatory response of mesenchymal stromal cells after in vivo exposure with selected trauma-related factors and polytrauma serum Journal Article 2019 10.1371/journal.pone.0216862 PLoS One 14 e0216862 5 https://www.ncbi.nlm.nih.gov/pubmed/31086407 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6516676/pdf/pone.0216862.pdf E. M. Amann A. Groß M. T. Rojewski H. A. Kestler M. Kalbitz R. E. Brenner M. Huber-Lang H. Schrezenmeier article RN437 Iron and iron-dependent reactive oxygen species in the regulation of macrophages and fibroblasts in non-healing chronic wounds Journal Article 2019 10.1016/j.freeradbiomed.2018.09.036 Free Radic Biol Med 133 262-275 https://www.ncbi.nlm.nih.gov/pubmed/30261274 M. Wlaschek K. Singh A. Sindrilaru D. Crisan K. Scharffetter-Kochanek article RN472 Is generation of C3(H2O) necessary for activation of the alternative pathway in real life? Journal Article 2019 10.1016/j.molimm.2019.07.032 Mol Immunol 114 353-361 https://www.ncbi.nlm.nih.gov/pubmed/31446306 K. N. Ekdahl C. Mohlin A. Adler A. Aman V. A. Manivel K. Sandholm M. Huber-Lang K. Fromell B. Nilsson article RN458 Immunostimulatory functions of adoptively transferred MDSCs in experimental blunt chest trauma Journal Article 2019 10.1038/s41598-019-44419-5 Sci Rep 9 7992 1 https://www.ncbi.nlm.nih.gov/pubmed/31142770 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6541619/pdf/41598_2019_Article_44419.pdf M. Kustermann M. Klingspor M. Huber-Lang K. M. Debatin G. Strauss article RN497 Neuroinflammation after Traumatic Brain Injury Is Enhanced in Activating Transcription Factor 3 Mutant Mice Journal Article 2018 10.1089/neu.2017.5593 J Neurotrauma 35 2317-2329 19 https://www.ncbi.nlm.nih.gov/pubmed/29463176 https://www.liebertpub.com/doi/10.1089/neu.2017.5593?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%3dpubmed P. Forstner R. Rehman S. Anastasiadou M. Haffner-Luntzer D. Sinske A. Ignatius F. Roselli B. Knöll article RN538 Online monitoring of carbon dioxide and oxygen in exhaled mouse breath via substrate-integrated hollow waveguide Fourier-transform infrared-luminescence spectroscopy Journal Article 2018 10.1088/1752-7163/aabf98 J Breath Res 12 036018 3 https://www.ncbi.nlm.nih.gov/pubmed/29674598 F. Seichter E. Tutuncu L. T. Hagemann J. Vogt U. Wachter M. Gröger S. Kress P. Radermacher B. Mizaikoff article RN20 Nutrient limitation affects presynaptic structures through dissociable Bassoon autophagic degradation and impaired vesicle release Journal Article 2018 10.1177/0271678X18786356 J Cereb Blood Flow Metab 38 1924-1939 11 https://www.ncbi.nlm.nih.gov/pubmed/29972341 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6259322/pdf/10.1177_0271678X18786356.pdf A. Catanese D. Garrido P. Walther F. Roselli T. M. Boeckers article RN213 NF-kappaB activation in astrocytes drives a stage-specific beneficial neuroimmunological response in ALS Journal Article 2018 10.15252/embj.201798697 EMBO J 37 e98697 16 https://www.ncbi.nlm.nih.gov/pubmed/29875132 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092622/pdf/EMBJ-37-e98697.pdf N. Ouali Alami C. Schurr F. Olde Heuvel L. Tang Q. Li A. Tasdogan A. Kimbara M. Nettekoven G. Ottaviani C. Raposo S. Rover M. Rogers-Evans B. Rothenhausler C. Ullmer J. Fingerle U. Grether I. Knuesel T. M. Boeckers A. Ludolph T. Wirth F. Roselli B. Baumann article RN160 New horizons for osteoanabolic treatment? Journal Article 2018 10.1038/s41574-018-0069-2 Nat Rev Endocrinol 14 508-509 9 https://doi.org/10.1038/s41574-018-0069-2 A. Ignatius J. Tuckermann article RN236 JunB defines functional and structural integrity of the epidermo-pilosebaceous unit in the skin Journal Article 2018 10.1038/s41467-018-05726-z Nat Commun 9 3425 1 https://www.ncbi.nlm.nih.gov/pubmed/30143626 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6109099/pdf/41467_2018_Article_5726.pdf K. Singh E. Camera L. Krug A. Basu R. K. Pandey S. Munir M. Wlaschek S. Kochanek M. Schorpp-Kistner M. Picardo P. Angel C. Niemann P. Maity K. Scharffetter-Kochanek article RN154 Neuroinflammation after traumatic brain injury (TBI) is enhanced in activating transcription factor 3 (ATF3) mutant mice Journal Article 2018 10.1089/neu.2017.5593 J Neurotrauma 35 2317-2329 19 https://www.ncbi.nlm.nih.gov/pubmed/29463176 P. Foerstner R. Rehman S. Anastasiadou M. Haffner-Luntzer D. Sinske A. Ignatius F. Roselli B. Knoell article RN518 Molecular mechanisms of glucocorticoids on skeleton and bone regeneration after fracture Journal Article 2018 10.1530/JME-18-0024 J Mol Endocrinol 61 R75-R90 1 https://www.ncbi.nlm.nih.gov/pubmed/29588427 Y. Hachemi A. E. Rapp A. K. Picke G. Weidinger A. Ignatius J. Tuckermann article RN483 Minimum Quality Threshold in Pre-Clinical Sepsis Studies (MQTiPSS): An International Expert Consensus Initiative for Improvement of Animal Modeling in Sepsis Journal Article 2018 10.1097/SHK.0000000000001212 Shock 50 377-380 4 https://www.ncbi.nlm.nih.gov/pubmed/30106875 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6133201/pdf/shk-50-377.pdf M. F. Osuchowski A. Ayala S. Bahrami M. Bauer M. Boros J. M. Cavaillon I. H. Chaudry C. M. Coopersmith C. S. Deutschman S. Drechsler P. Efron C. Frostell G. Fritsch W. Gozdzik J. Hellman M. Huber-Lang S. Inoue S. Knapp A. V. Kozlov C. Libert J. C. Marshall L. L. Moldawer P. Radermacher H. Redl D. G. Remick M. Singer C. Thiemermann P. Wang W. J. Wiersinga X. Xiao B. Zingarelli article RN496 Loss of p53 compensates osteopenia in murine Mysm1 deficiency Journal Article 2018 10.1096/fj.201700871R FASEB J 32 1957-1968 4 http://www.fasebj.org/content/early/2017/12/01/fj.201700871R.abstract Melanie Haffner-Luntzer Anna Kovtun Verena Fischer Katja Prystaz Adelheid Hainzl Carsten M. Kroeger Ioanna Krikki Titus J. Brinker Anita Ignatius Martina Gatzka article RN511 Less immune activation following social stress in rural vs. urban participants raised with regular or no animal contact, respectively Journal Article 2018 10.1073/pnas.1719866115 Proc Natl Acad Sci U S A 115 5259-5264 20 https://www.ncbi.nlm.nih.gov/pubmed/29712842 T. S. Böbel S. B. Hackl D. Langgartner M. N. Jarczok N. Rohleder G. A. Rook C. A. Lowry H. Gundel C. Waller S. O. Reber article RN477 PKD regulates actin polymerization, neutrophil deformability, and transendothelial migration in response to fMLP and trauma Journal Article 2018 10.1002/JLB.4A0617-251RR J Leukoc Biol 104 615-630 3 https://www.ncbi.nlm.nih.gov/pubmed/29656400 https://jlb.onlinelibrary.wiley.com/doi/pdfdirect/10.1002/JLB.4A0617-251RR?download=true C. Wille T. Eiseler S. T. Langenberger J. Richter K. Mizuno P. Radermacher U. Knippschild M. Huber-Lang T. Seufferlein S. Paschke article RN40 P2X4 receptor re-sensitization depends on a protonation/deprotonation cycle mediated by receptor internalization and recycling Journal Article 2018 10.1113/JP275448 J Physiol 596 4893-4907 20 https://www.ncbi.nlm.nih.gov/pubmed/30144063 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6187034/pdf/TJP-596-4893.pdf G. Fois K. J. Fohr C. Kling M. Fauler O. H. Wittekindt P. Dietl M. Frick article RN91 The Neuroprotective Effect of Ethanol Intoxication in Traumatic Brain Injury Is Associated with the Suppression of ErbB Signaling in Parvalbumin-Positive Interneurons Journal Article 2018 10.1089/neu.2017.5270 J Neurotrauma 35 2718-2735 22 https://www.ncbi.nlm.nih.gov/pubmed/29774782 https://www.liebertpub.com/doi/10.1089/neu.2017.5270?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%3dpubmed A. Chandrasekar F. Olde Heuvel M. Wepler R. Rehman A. Palmer A. Catanese B. Linkus A. Ludolph T. Boeckers M. Huber-Lang P. Radermacher F. Roselli article RN51 Pulmonary surfactant protein SP-B promotes exocytosis of lamellar bodies in alveolar type II cells Journal Article 2018 10.1096/fj.201701462RR FASEB J 32 4600-4611 8 https://www.ncbi.nlm.nih.gov/pubmed/29543530 https://faseb.onlinelibrary.wiley.com/doi/pdfdirect/10.1096/fj.201701462RR?download=true M. Martinez-Calle B. Olmeda P. Dietl M. Frick J. Perez-Gil article RN542 Reversible induction of TDP-43 granules in cortical neurons after traumatic injury Journal Article 2018 10.1016/j.expneurol.2017.09.011 Exp Neurol 299 15-25 Pt A https://www.ncbi.nlm.nih.gov/pubmed/28941811 D. Wiesner L. Tar B. Linkus A. Chandrasekar F. Olde Heuvel L. Dupuis W. Tsao P. C. Wong A. Ludolph F. Roselli article RN529 Rho-inhibiting C2IN-C3 fusion toxin inhibits chemotactic recruitment of human monocytes ex vivo and in mice in vivo Journal Article 2018 10.1007/s00204-017-2058-y Arch Toxicol 92 323-336 1 https://www.ncbi.nlm.nih.gov/pubmed/28924833 T. Martin A. Moglich I. Felix C. Förtsch A. Rittlinger A. Palmer S. Denk J. Schneider L. Notbohm M. Vogel H. Geiger S. Paschke M. Huber-Lang H. Barth article RN516 Role of Hemorrhagic Shock in Experimental Polytrauma Journal Article 2018 10.1097/SHK.0000000000000925 Shock 49 154-163 2 https://www.ncbi.nlm.nih.gov/pubmed/28614141 S. Denk S. Weckbach P. Eisele C. K. Braun R. Wiegner J. J. Ohmann L. Wrba F. M. Hoenes P. Kellermann P. Radermacher U. Wachter S. Häfner O. McCook A. Schultze A. Palmer S. Braumuller F. Gebhard M. Huber-Lang article RN165 Role of the Complement System in the Response to Orthopedic Biomaterials Journal Article 2018 10.3390/ijms19113367 Int J Mol Sci 19 3367 11 http://www.mdpi.com/1422-0067/19/11/3367 Yvonne Mödinger Graciosa Teixeira Cornelia Neidlinger-Wilke Anita Ignatius article RN221 Single-molecule imaging correlates decreasing nuclear volume with increasing TF-chromatin associations during zebrafish development Journal Article 2018 10.1038/s41467-018-07731-8 Nat Commun 9 5218 1 https://www.ncbi.nlm.nih.gov/pubmed/30523256 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6283880/pdf/41467_2018_Article_7731.pdf M. Reisser A. Palmer A. P. Popp C. Jahn G. Weidinger J. C. M. Gebhardt article RN22 Stage-dependent remodeling of projections to motor cortex in ALS mouse model revealed by a new variant retrograde-AAV9 Journal Article 2018 10.7554/eLife.36892 eLife 7 e36892 https://www.ncbi.nlm.nih.gov/pubmed/30136928 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6125125/pdf/elife-36892.pdf B. Commisso L. Ding K. Varadi M. Gorges D. Bayer T. M. Boeckers A. C. Ludolph J. Kassubek O. J. Muller F. Roselli article RN481 Structural basis for PDZ domain interactions in the post-synaptic density scaffolding protein Shank3 Journal Article 2018 10.1111/jnc.14322 Journal of Neurochemistry 145 449-463 6 ://WOS:000437127500003 https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/jnc.14322?download=true S. K. Ponna S. Ruskamo M. Myllykoski C. Keller T. M. Boeckers P. Kursula article RN509 Systemic recovery and therapeutic effects of transplanted allogenic and xenogenic mesenchymal stromal cells in a rat blunt chest trauma model Journal Article 2018 10.1016/j.jcyt.2017.11.005 Cytotherapy 20 218-231 2 https://www.sciencedirect.com/science/article/pii/S146532491730720X?via%3Dihub Elisa Maria Amann Markus Thomas Rojewski Sinja Rodi Daniel Fürst Jörg Fiedler Annette Palmer Sonja Braumüller Markus Huber-Lang Hubert Schrezenmeier Rolf Erwin Brenner article RN209 The multifaceted role of complement in kidney transplantation Journal Article 2018 10.1038/s41581-018-0071-x Nat Rev Nephrol 14 767-781 12 https://www.ncbi.nlm.nih.gov/pubmed/30367174 https://www.nature.com/articles/s41581-018-0071-x A. R. Biglarnia M. Huber-Lang C. Mohlin K. N. Ekdahl B. Nilsson article RN92 Interaction of the hydrogen sulfide system with the oxytocin system in the injured mouse heart Journal Article 2018 10.1186/s40635-018-0207-0 Intensive Care Med Exp 6 41 1 https://www.ncbi.nlm.nih.gov/pubmed/30341744 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6195501/pdf/40635_2018_Article_207.pdf T. Merz B. Lukaschewski D. Wigger A. Rupprecht M. Wepler M. Gröger C. Hartmann M. Whiteman C. Szabo R. Wang C. Waller P. Radermacher O. McCook article RN32 Thirty-eight-negative kinase 1 mediates trauma-induced intestinal injury and multi-organ failure Journal Article 2018 10.1172/JCI97912 J Clin Invest 128 5056-5072 11 https://www.ncbi.nlm.nih.gov/pubmed/30320600 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6205400/pdf/jci-128-97912.pdf M. Armacki A. K. Trugenberger A. K. Ellwanger T. Eiseler C. Schwerdt L. Bettac D. Langgartner N. Azoitei R. Halbgebauer R. Groß T. Barth A. Lechel B. M. Walter J. M. Kraus C. Wiegreffe J. Grimm A. Scheffold M. R. Schneider K. Peuker S. Zeißig S. Britsch S. Rose-John S. Vettorazzi E. Wolf A. Tannapfel K. Steinestel S. O. Reber P. Walther H. A. Kestler P. Radermacher T. F. Barth M. Huber-Lang A. Kleger T. Seufferlein article RN535 Thy-1 (CD90) promotes bone formation and protects against obesity Journal Article 2018 10.1126/scitranslmed.aao6806 Sci Transl Med 10 453 https://www.ncbi.nlm.nih.gov/pubmed/30089635 A. K. Picke G. M. Campbell M. Blüher U. Krügel F. N. Schmidt E. Tsourdi M. Winzer M. Rauner V. Vukicevic B. Busse J. Salbach-Hirsch J. P. Tuckermann J. C. Simon U. Anderegg L. C. Hofbauer A. Saalbach article RN479 Interferons in Traumatic Brain and Spinal Cord Injury: Current Evidence for Translational Application Journal Article 2018 10.3389/fneur.2018.00458 Front Neurol 9 458 https://www.ncbi.nlm.nih.gov/pubmed/29971040 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6018073/pdf/fneur-09-00458.pdf F. Roselli A. Chandrasekar M. C. Morganti-Kossmann article RN493 Janus face of complement-driven neutrophil activation during sepsis Journal Article 2018 10.1016/j.smim.2018.02.004 Semin Immunol 37 12-30 https://www.sciencedirect.com/science/article/pii/S1044532317301173 R. Halbgebauer C. Q. Schmidt C. M. Karsten A. Ignatius M. Huber-Lang article RN523 Innate immune responses to trauma Journal Article 2018 10.1038/s41590-018-0064-8 Nat Immunol 19 327-341 4 https://www.ncbi.nlm.nih.gov/pubmed/29507356 M. Huber-Lang J. D. Lambris P. A. Ward article RN93 Cystathionine-gamma-lyase expression is associated with mitochondrial respiration during sepsis-induced acute kidney injury in swine with atherosclerosis Journal Article 2018 10.1186/s40635-018-0208-z Intensive Care Med Exp 6 43 1 https://www.ncbi.nlm.nih.gov/pubmed/30343340 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6195873/pdf/40635_2018_Article_208.pdf T. Merz M. Wepler B. Nussbaum J. Vogt E. Calzia R. Wang C. Szabo P. Radermacher O. McCook article RN491 [Mutual influence of immune system and bones] Journal Article 2018 10.1007/s00393-018-0454-1 Z Rheumatol 77 8-11 Suppl 1 https://www.ncbi.nlm.nih.gov/pubmed/29675686 https://link.springer.com/content/pdf/10.1007/s00393-018-0454-1.pdf T. Kamradt M. Amling B. Dankbar A. Dudeck M. Gunzer A. Ignatius G. Krönke K. Kubatzky T. Pap I. Prinz G. Schett T. Schinke J. Tuckermann A. Waisman article RN514 Association of child maltreatment subtypes and long-term physical health in a German representative sample Journal Article 2018 10.1080/20008198.2018.1510278 Eur J Psychotraumatol 9 1510278 1 https://www.ncbi.nlm.nih.gov/pubmed/30220980 V. Clemens M. Huber-Lang P. L. Plener E. Brahler R. C. Brown J. M. Fegert article RN500 Influence of Menopause on Inflammatory Cytokines during Murine and Human Bone Fracture Healing Journal Article 2018 10.3390/ijms19072070 Int J Mol Sci 19 2070 7 https://www.ncbi.nlm.nih.gov/pubmed/30013010 V. Fischer M. Kalbitz F. Muller-Graf F. Gebhard A. Ignatius A. Liedert M. Haffner-Luntzer article RN517 Autonomous Ultrafast Self-Healing Hydrogels by pH-Responsive Functional Nanofiber Gelators as Cell Matrices Journal Article 2018 10.1002/adma.201805044 Adv Mater In Press e1805044 2 https://www.ncbi.nlm.nih.gov/pubmed/30411838 J. Gačanin J. Hedrich S. Sieste G. Glasser I. Lieberwirth C. Schilling S. Fischer H. Barth B. Knöll C. V. Synatschke T. Weil article RN522 Auxiliary activation of the complement system and its importance for the pathophysiology of clinical conditions Journal Article 2018 10.1007/s00281-017-0646-9 Semin Immunopathol 40 87-102 1 https://www.ncbi.nlm.nih.gov/pubmed/28900700 M. Huber-Lang K. N. Ekdahl R. Wiegner K. Fromell B. Nilsson article RN540 Before the ICU: does emergency room hyperoxia affect outcome? Journal Article 2018 10.1186/s13054-018-1980-6 Crit Care 22 59 1 https://www.ncbi.nlm.nih.gov/pubmed/29519235 M. Wepler J. Demiselle P. Radermacher P. Asfar E. Calzia article RN526 Boosting Antitumor Drug Efficacy with Chemically Engineered Multidomain Proteins Journal Article 2018 10.1002/advs.201701036 Adv Sci (Weinh) 5 1701036 8 https://www.ncbi.nlm.nih.gov/pubmed/30128225 S. L. Kuan S. Fischer S. Häfner T. Wang T. Syrovets W. Liu Y. Tokura D. Y. W. Ng A. Riegger C. Förtsch D. Jager T. F. E. Barth T. Simmet H. Barth T. Weil article RN164 C5aR1 interacts with TLR2 in osteoblasts and stimulates the osteoclast-inducing chemokine CXCL10 Journal Article 2018 10.1111/jcmm.13873 J Cell Mol Med 22 6002-6014 12 https://onlinelibrary.wiley.com/doi/abs/10.1111/jcmm.13873 Yvonne Mödinger Anna Rapp Julia Pazmandi Anna Vikman Karlheinz Holzmann Melanie Haffner-Luntzer Markus Huber-Lang Anita Ignatius article RN501 Calcium and vitamin D in bone fracture healing and post-traumatic bone turnover Journal Article 2018 10.22203/eCM.v035a25 Eur Cell Mater 35 365-385 https://www.ncbi.nlm.nih.gov/pubmed/29931664 V. Fischer M. Haffner-Luntzer M. Amling A. Ignatius article RN508 Cell-based RNAi screening and high-content analysis in primary calvarian osteoblasts applied to identification of osteoblast differentiation regulators Journal Article 2018 10.1038/s41598-018-32364-8 Sci Rep 8 14045 1 https://www.ncbi.nlm.nih.gov/pubmed/30232406 M. Ahmad T. Kroll J. Jakob A. Rauch A. Ploubidou J. Tuckermann article RN541 Comparison of Fatty Acid and Gene Profiles in Skeletal Muscle in Normal and Obese C57BL/6J Mice before and after Blunt Muscle Injury Journal Article 2018 10.3389/fphys.2018.00019 Front Physiol 9 19 https://www.ncbi.nlm.nih.gov/pubmed/29441023 J. U. Werner K. Todter P. Xu L. Lockhart M. Jahnert P. Gottmann A. Schurmann L. Scheja M. Wabitsch U. Knippschild article RN208 Complement After Trauma: Suturing Innate and Adaptive Immunity Journal Article 2018 10.3389/fimmu.2018.02050 Front Immunol 9 2050 https://www.ncbi.nlm.nih.gov/pubmed/30319602 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6165897/pdf/fimmu-09-02050.pdf S. Chakraborty E. Karasu M. Huber-Lang article RN532 Complement C5a Alters the Membrane Potential of Neutrophils during Hemorrhagic Shock Journal Article 2018 10.1155/2018/2052356 Mediators Inflamm 2018 2052356 https://www.ncbi.nlm.nih.gov/pubmed/30002598 D. A. C. Messerer S. Denk K. J. Fohr R. Halbgebauer C. K. Braun F. Hones J. Harant M. Fauler M. Frick B. L. Nussbaum P. Radermacher S. Häfner M. S. Huber-Lang article RN512 Associations of adverse childhood experiences and bullying on physical pain in the general population of Germany Journal Article 2018 10.2147/JPR.S169135 J Pain Res 11 3099-3108 https://www.ncbi.nlm.nih.gov/pubmed/30584352 R. C. Brown P. L. Plener E. Braehler J. M. Fegert M. Huber-Lang article RN527 Deletion of Menin in craniofacial osteogenic cells in mice elicits development of mandibular ossifying fibroma Journal Article 2018 10.1038/onc.2017.364 Oncogene 37 616-626 5 https://www.ncbi.nlm.nih.gov/pubmed/28991228 S. Lee P. Liu R. Teinturier J. Jakob M. Tschaffon A. Tasdogan R. Wittig S. Hoeller D. Baumhoer L. Frappart S. Vettorazzi P. Bertolino C. Zhang J. Tuckermann article RN528 Hemodynamic support in the early phase of septic shock: a review of challenges and unanswered questions Journal Article 2018 10.1186/s13613-018-0449-8 Ann Intensive Care 8 102 1 https://www.ncbi.nlm.nih.gov/pubmed/30374729 O. Lesur E. Delile P. Asfar P. Radermacher article RN543 Diet-Induced Obesity Affects Muscle Regeneration After Murine Blunt Muscle Trauma-A Broad Spectrum Analysis Journal Article 2018 10.3389/fphys.2018.00674 Front Physiol 9 674 https://www.ncbi.nlm.nih.gov/pubmed/29922174 P. Xu J. U. Werner S. Milerski C. M. Hamp T. Kuzenko M. Jahnert P. Gottmann L. Roy D. Warnecke A. Abaei A. Palmer M. Huber-Lang L. Dürselen V. Rasche A. Schurmann M. Wabitsch U. Knippschild article RN533 IKK2/NF-kappaB signaling protects neurons after traumatic brain injury Journal Article 2018 10.1096/fj.201700826R FASEB J 32 1916-1932 4 https://www.ncbi.nlm.nih.gov/pubmed/29187362 M. Mettang S. N. Reichel M. Lattke A. Palmer A. Abaei V. Rasche M. Huber-Lang B. Baumann T. Wirth article RN515 Hyperoxia toxicity in septic shock patients according to the Sepsis-3 criteria: a post hoc analysis of the HYPER2S trial Journal Article 2018 10.1186/s13613-018-0435-1 Ann Intensive Care 8 90 1 https://www.ncbi.nlm.nih.gov/pubmed/30225670 J. Demiselle M. Wepler C. Hartmann P. Radermacher F. Schortgen F. Meziani M. Singer V. Seegers P. Asfar Hyper S. investigators article RN520 Hemorrhagic shock drives glycocalyx, barrier and organ dysfunction early after polytrauma Journal Article 2018 10.1016/j.jcrc.2017.11.025 J Crit Care 44 229-237 https://www.ncbi.nlm.nih.gov/pubmed/29175047 R. Halbgebauer C. K. Braun S. Denk B. Mayer P. Cinelli P. Radermacher G. A. Wanner H. P. Simmen F. Gebhard D. Rittirsch M. Huber-Lang article RN537 Induced global deletion of glucocorticoid receptor impairs fracture healing Journal Article 2018 10.1096/fj.201700459RR FASEB J 32 2235-2245 4 https://www.ncbi.nlm.nih.gov/pubmed/29217668 A. E. Rapp Y. Hachemi J. Kemmler M. Koenen J. Tuckermann A. Ignatius article RN521 Glucocorticoids suppress Wnt16 expression in osteoblasts in vitro and in vivo Journal Article 2018 10.1038/s41598-018-26300-z Sci Rep 8 8711 1 https://www.ncbi.nlm.nih.gov/pubmed/29880826 S. Hildebrandt U. Baschant S. Thiele J. Tuckermann L. C. Hofbauer M. Rauner article RN536 Distinct Effects of IL-6 Classic and Trans-Signaling in Bone Fracture Healing Journal Article 2018 10.1016/j.ajpath.2017.10.011 Am J Pathol 188 474-490 2 https://www.ncbi.nlm.nih.gov/pubmed/29146294 K. Prystaz K. Kaiser A. Kovtun M. Haffner-Luntzer V. Fischer A. E. Rapp A. Liedert G. Strauss G. H. Waetzig S. Rose-John A. Ignatius article RN519 Estrogen receptor alpha- (ERalpha), but not ERbeta-signaling, is crucially involved in mechanostimulation of bone fracture healing by whole-body vibration Journal Article 2018 10.1016/j.bone.2018.01.017 Bone 110 11-20 https://www.ncbi.nlm.nih.gov/pubmed/29367057 M. Haffner-Luntzer A. Kovtun I. Lackner Y. Mödinger S. Hacker A. Liedert J. Tuckermann A. Ignatius article RN539 Endogenous glucocorticoid signaling in chondrocytes attenuates joint inflammation and damage Journal Article 2018 10.1096/fj.201700659R FASEB J 32 478-487 1 https://www.ncbi.nlm.nih.gov/pubmed/28928247 J. Tu S. Stoner P. D. Fromm T. Wang D. Chen J. Tuckermann M. S. Cooper M. J. Seibel H. Zhou article RN158 Effects of low-magnitude high-frequency vibration on osteoblasts are dependent on estrogen receptor alpha signaling and cytoskeletal remodeling Journal Article 2018 10.1016/j.bbrc.2018.08.023 Biochem Biophys Res Commun 503 2678-2684 4 https://www.ncbi.nlm.nih.gov/pubmed/30093109 M. Haffner-Luntzer I. Lackner A. Liedert V. Fischer A. Ignatius article RN525 Glucocorticoid receptor in stromal cells is essential for glucocorticoid-mediated suppression of inflammation in arthritis Journal Article 2018 10.1136/annrheumdis-2017-212762 Ann Rheum Dis 77 1610-1618 11 https://www.ncbi.nlm.nih.gov/pubmed/29997111 M. Koenen S. Culemann S. Vettorazzi G. Caratti L. Frappart W. Baum G. Krönke U. Baschant J. P. Tuckermann article RN130 Osteopontin attenuates aging-associated phenotypes of hematopoietic stem cells Journal Article 2017 10.15252/embj.201796968 EMBO J 36 1463 10 https://www.ncbi.nlm.nih.gov/pubmed/28507084 N. Guidi M. Sacma L. Standker K. Soller G. Marka K. Eiwen J. M. Weiss F. Kirchhoff T. Weil J. A. Cancelas M. C. Florian H. Geiger article RN7 Osteoblast-specific overexpression of complement receptor C5aR1 impairs fracture healing Journal Article 2017 10.1371/journal.pone.0179512 PLoS One 12 e0179512 6 https://www.ncbi.nlm.nih.gov/pubmed/28614388 S. Bergdolt A. Kovtun Y. Hagele A. Liedert T. Schinke M. Amling M. Huber-Lang A. Ignatius article RN170 Nonlinear calibration transfer based on hierarchical Bayesian models and Lagrange Multipliers: Error bounds of estimates via Monte Carlo - Markov Chain sampling Journal Article 2017 10.1016/j.aca.2016.11.025 Anal Chim Acta 951 32-45 https://www.ncbi.nlm.nih.gov/pubmed/27998484 F. Seichter J. Vogt P. Radermacher B. Mizaikoff article RN88 Non-Hemodynamic Effects of Catecholamines Journal Article 2017 10.1097/SHK.0000000000000879 Shock 48 390-400 4 https://www.ncbi.nlm.nih.gov/pubmed/28915214 C. Hartmann P. Radermacher M. Wepler B. Nussbaum article RN59 MDSCs are induced after experimental blunt chest trauma and subsequently alter antigen-specific T cell responses Journal Article 2017 10.1038/s41598-017-13019-6 Sci Rep 7 12808 1 https://www.ncbi.nlm.nih.gov/pubmed/28993671 Y. Husecken S. Muche M. Kustermann M. Klingspor A. Palmer S. Braumuller M. Huber-Lang K. M. Debatin G. Strauss article RN135 MicroRNA-155 promotes G-CSF-induced mobilization of murine hematopoietic stem and progenitor cells via propagation of CXCL12 signaling Journal Article 2017 10.1038/leu.2017.50 Leukemia 31 1247-1250 5 https://www.ncbi.nlm.nih.gov/pubmed/28174416 T. Itkin A. Kumari E. Schneider S. Gur-Cohen C. Ludwig R. Brooks O. Kollet K. Golan E. Khatib-Massalha C. M. Russo J. D. Chisholm A. Rouhi H. Geiger E. Hornstein W. G. Kerr F. Kuchenbauer T. Lapidot article RN68 Microglia contribute to normal myelinogenesis and to oligodendrocyte progenitor maintenance during adulthood Journal Article 2017 10.1007/s00401-017-1747-1 Acta Neuropathol 134 441-458 3 https://www.ncbi.nlm.nih.gov/pubmed/28685323 N. Hagemeyer K. M. Hanft M. A. Akriditou N. Unger E. S. Park E. R. Stanley O. Staszewski L. Dimou M. Prinz article RN99 Individual differences in stress vulnerability: The role of gut pathobionts in stress-induced colitis Journal Article 2017 10.1016/j.bbi.2016.12.019 Brain Behav Immun 64 23-32 https://www.ncbi.nlm.nih.gov/pubmed/28012830 D. Langgartner D. Peterlik S. Foertsch A. M. Fuchsl P. Brokmann P. J. Flor Z. Shen J. G. Fox N. Uschold-Schmidt C. A. Lowry S. O. Reber article RN115 Loss of menin in osteoblast lineage affects osteocyte-osteoclast crosstalk causing osteoporosis Journal Article 2017 10.1038/cdd.2016.165 Cell Death Differ 24 672-682 4 https://www.ncbi.nlm.nih.gov/pubmed/28106886 P. Liu S. Lee J. Knoll A. Rauch S. Ostermay J. Luther N. Malkusch U. H. Lerner M. M. Zaiss M. Neven R. Wittig M. Rauner J. P. David P. Bertolino C. X. Zhang J. P. Tuckermann article RN128 Live cell screening platform identifies PPARdelta as a regulator of cardiomyocyte proliferation and cardiac repair Journal Article 2017 10.1038/cr.2017.84 Cell Res 27 1002-1019 8 https://www.ncbi.nlm.nih.gov/pubmed/28621328 A. Magadum Y. Ding L. He T. Kim M. D. Vasudevarao Q. Long K. Yang N. Wickramasinghe H. V. Renikunta N. Dubois G. Weidinger Q. Yang F. B. Engel article RN169 Response-surface fits and calibration transfer for the correction of the oxygen effect in the quantification of carbon dioxide via FTIR spectroscopy Journal Article 2017 10.1016/j.aca.2017.03.053 Anal Chim Acta 972 16-27 https://www.ncbi.nlm.nih.gov/pubmed/28495092 F. Seichter J. Vogt P. Radermacher B. Mizaikoff article RN237 Oxygen in the Heart: How Much is too Much? Journal Article 2017 10.1097/SHK.0000000000000760 Shock 47 531-532 4 https://www.ncbi.nlm.nih.gov/pubmed/27749760 M. Kalbitz C. Waller M. Huber-Lang F. Gebhard C. Thiemermann P. Radermacher article RN16 The inflammatory phase of fracture healing is influenced by oestrogen status in mice Journal Article 2017 10.1186/s40001‐017‐0264‐y Eur J Med Res 33 23 1 M Haffner-Luntzer V. Fischer K. Prystaz A. Liedert A Ignatius article RN106 Role of the Purinergic Receptor P2XR4 After Blunt Chest Trauma in Cigarette Smoke-Exposed Mice Journal Article 2017 10.1097/SHK.0000000000000726 Shock 47 193-199 2 https://www.ncbi.nlm.nih.gov/pubmed/27559703 S. Häfner K. Wagner S. Weber M. Gröger M. Wepler O. McCook A. Scheuerle B. Stahl M. Huber-Lang B. Jung E. Calzia M. Georgieff P. Möller M. Frick P. Radermacher F. Wagner article RN151 Serum Response Factor (SRF) Ablation Interferes with Acute Stress-Associated Immediate and Long-Term Coping Mechanisms Journal Article 2017 10.1007/s12035-016-0300-x Mol Neurobiol 54 8242-8262 10 https://www.ncbi.nlm.nih.gov/pubmed/27914009 A. Zimprich G. Mroz C. Meyer Zu Reckendorf S. Anastasiadou P. Forstner L. Garrett S. M. Holter L. Becker J. Rozman C. Prehn B. Rathkolb K. Moreth W. Wurst T. Klopstock M. Klingenspor J. Adamski E. Wolf R. Bekeredjian H. Fuchs V. Gailus-Durner M. H. Angelis B. Knöll article RN9 Spatiotemporally Controlled Release of Rho-Inhibiting C3 Toxin from a Protein–DNA Hybrid Hydrogel for Targeted Inhibition of Osteoclast Formation and Activity Journal Article 2017 10.1002/adhm.201700392 Adv Healthc Mater 6 1700392 21 http://dx.doi.org/10.1002/adhm.201700392 Jasmina Gačanin Anna Kovtun Stephan Fischer Victoria Schwager Johanna Quambusch Seah Ling Kuan Weina Liu Felix Boldt Chuang Li Zhongqiang Yang Dongsheng Liu Yuzhou Wu Tanja Weil Holger Barth Anita Ignatius article RN57 Splenic glucocorticoid resistance following psychosocial stress requires physical injury Journal Article 2017 10.1038/s41598-017-15897-2 Sci Rep 7 15730 1 https://www.ncbi.nlm.nih.gov/pubmed/29146967 S. Foertsch A. M. Fuchsl S. D. Faller H. Holzer D. Langgartner J. Messmann G. Strauss S. O. Reber article RN183 SRF modulates seizure occurrence, activity induced gene transcription and hippocampal circuit reorganization in the mouse pilocarpine epilepsy model Journal Article 2017 10.1186/s13041-017-0310-2 Mol Brain 10 30 1 https://www.ncbi.nlm.nih.gov/pubmed/28716058 P. Losing C. E. Niturad M. Harrer C. M. Z. Reckendorf T. Schatz D. Sinske H. Lerche S. Maljevic B. Knöll article RN245 The glucocorticoid receptor in monocyte-derived macrophages is critical for cardiac infarct repair and remodeling Journal Article 2017 10.1096/fj.201700317R FASEB J 31 5122-5132 11 https://www.ncbi.nlm.nih.gov/pubmed/28768721 P. Galuppo S. Vettorazzi J. Hövelmann C. J. Scholz J. P. Tuckermann J. Bauersachs D. Fraccarollo article RN109 The Role of Cystathionine-gamma-Lyase In Blunt Chest Trauma in Cigarette Smoke Exposed Mice Journal Article 2017 10.1097/SHK.0000000000000746 Shock 47 491-499 4 https://www.ncbi.nlm.nih.gov/pubmed/27685807 C. Hartmann S. Häfner A. Scheuerle P. Möller M. Huber-Lang B. Jung B. Nubaum O. McCook M. Gröger F. Wagner S. Weber B. Stahl E. Calzia M. Georgieff C. Szabo R. Wang P. Radermacher K. Wagner article RN66 The role of oligodendrocyte precursor cells expressing the GPR17 receptor in brain remodeling after stroke Journal Article 2017 10.1038/cddis.2017.256 Cell Death Dis 8 e2871 6 https://www.ncbi.nlm.nih.gov/pubmed/28594400 E. Bonfanti P. Gelosa M. Fumagalli L. Dimou F. Vigano E. Tremoli M. Cimino L. Sironi M. P. Abbracchio article RN155 The Role of Troponin in Blunt Cardiac Injury After Multiple Trauma in Humans Journal Article 2017 10.1007/s00268-016-3650-7 World J Surg 41 162-169 1 https://www.ncbi.nlm.nih.gov/pubmed/27501709 M. Kalbitz J. Pressmar J. Stecher B. Weber M. Weiss S. Schwarz E. Miltner F. Gebhard M. Huber-Lang article RN37 Transient IKK2 activation in astrocytes initiates selective non-cell-autonomous neurodegeneration Journal Article 2017 10.1186/s13024-017-0157-0 Mol Neurodegener 12 16 1 https://www.ncbi.nlm.nih.gov/pubmed/28193238 M. Lattke S. N. Reichel A. Magnutzki A. Abaei V. Rasche P. Walther D. P. Calado B. Ferger T. Wirth B. Baumann article RN126 Wnt signaling controls pro-regenerative Collagen XII in functional spinal cord regeneration in zebrafish Journal Article 2017 10.1038/s41467-017-00143-0 Nat Commun 8 126 1 https://www.ncbi.nlm.nih.gov/pubmed/28743881 D. Wehner T. M. Tsarouchas A. Michael C. Haase G. Weidinger M. M. Reimer T. Becker C. G. Becker article RN36 Zinc deficiency and low enterocyte zinc transporter expression in human patients with autism related mutations in SHANK3 Journal Article 2017 10.1038/srep45190 Sci Rep 7 45190 https://www.ncbi.nlm.nih.gov/pubmed/28345660 S. Pfaender A. K. Sauer S. Hagmeyer K. Mangus L. Linta S. Liebau J. Bockmann G. Huguet T. Bourgeron T. M. Boeckers A. M. Grabrucker article RN178 Inhibiting P. fluorescens biofilms with fluoropolymer-embedded silver nanoparticles: an in-situ spectroscopic study Journal Article 2017 10.1038/s41598-017-12088-x Sci Rep 7 11870 1 https://www.ncbi.nlm.nih.gov/pubmed/28928400 M. C. Sportelli E. Tutuncu R. A. Picca M. Valentini A. Valentini C. Kranz B. Mizaikoff H. Barth N. Cioffi article RN2 Mast cells are critical regulators of bone fracture-induced inflammation and osteoclast formation and activity Journal Article 2017 10.1002/jbmr.3234 J Bone Miner Res 32 2431–2444 12 https://www.ncbi.nlm.nih.gov/pubmed/28777474 J. Kroner A. Kovtun J. Kemmler J. J. Messmann G. Strauss S. Seitz T. Schinke M. Amling J. Kotrba J. Dudeck A. Dudeck A. Ignatius article RN20 In Vivo Evaluation of Fracture Callus Development During Bone Healing in Mice Using an MRI-compatible Osteosynthesis Device for the Mouse Femur Journal Article 2017 10.3791/56679 J Vis Exp e56679 129 https://www.ncbi.nlm.nih.gov/pubmed/29286432 M. Haffner-Luntzer F. Muller-Graf R. Matthys A. Abaei R. Jonas F. Gebhard V. Rasche A. Ignatius article RN180 Directing intracellular supramolecular assembly with N-heteroaromatic quaterthiophene analogues Journal Article 2017 10.1038/s41467-017-02020-2 Nat Commun 8 1850 1 https://www.ncbi.nlm.nih.gov/pubmed/29185444 D. Y. W. Ng R. Vill Y. Wu K. Koynov Y. Tokura W. Liu S. Sihler A. Kreyes S. Ritz H. Barth U. Ziener T. Weil article RN79 Impact of hyperglycemia on cystathionine-gamma-lyase expression during resuscitated murine septic shock Journal Article 2017 10.1186/s40635-017-0140-7 Intensive Care Med Exp 5 30 1 https://www.ncbi.nlm.nih.gov/pubmed/28616781 T. Merz J. A. Vogt U. Wachter E. Calzia C. Szabo R. Wang P. Radermacher O. McCook article RN93 Acute ethanol administration results in a protective cytokine and neuroinflammatory profile in traumatic brain injury Journal Article 2017 10.1016/j.intimp.2017.08.002 Int Immunopharmacol 51 66-75 https://www.ncbi.nlm.nih.gov/pubmed/28806641 A. Chandrasekar F. O. Heuvel A. Palmer B. Linkus A. C. Ludolph T. M. Boeckers B. Relja M. Huber-Lang F. Roselli article RN181 Adipocyte Glucocorticoid Receptor Deficiency Attenuates Aging- and HFD-Induced Obesity and Impairs the Feeding-Fasting Transition Journal Article 2017 10.2337/db16-0381 Diabetes 66 272-286 2 https://www.ncbi.nlm.nih.gov/pubmed/27650854 K. M. Mueller K. Hartmann D. Kaltenecker S. Vettorazzi M. Bauer L. Mauser S. Amann S. Jall K. Fischer H. Esterbauer T. D. Müller M. H. Tschöp C. Magnes J. Haybaeck T. Scherer N. Bordag J. P. Tuckermann R. Moriggl article RN136 Alpha-Ketoglutarate Curbs Differentiation and Induces Cell Death in Mesenchymal Stromal Precursors with Mitochondrial Dysfunction Journal Article 2017 10.1002/stem.2629 Stem Cells 35 1704-1718 7 https://www.ncbi.nlm.nih.gov/pubmed/28398002 K. Singh L. Krug A. Basu P. Meyer N. Treiber S. Vander Beken M. Wlaschek S. Kochanek W. Bloch H. Geiger P. Maity K. Scharffetter-Kochanek article RN210 Cardiac Depression in Pigs after Multiple Trauma - Characterization of Posttraumatic Structural and Functional Alterations Journal Article 2017 10.1038/s41598-017-18088-1 Sci Rep 7 17861 1 https://www.ncbi.nlm.nih.gov/pubmed/29259232 M. Kalbitz S. Schwarz B. Weber B. Bosch J. Pressmar F. M. Hoenes C. K. Braun K. Horst T. P. Simon R. Pfeifer P. Stormann H. Hummler F. Gebhard H. C. Pape M. Huber-Lang F. Hildebrand Treat Research Group article RN182 Cardiovascular disease and resuscitated septic shock lead to the downregulation of the H2S-producing enzyme cystathionine-gamma-lyase in the porcine coronary artery Journal Article 2017 10.1186/s40635-017-0131-8 Intensive Care Med Exp 5 17 1 https://www.ncbi.nlm.nih.gov/pubmed/28321823 T. Merz T. Stenzel B. Nussbaum M. Wepler C. Szabo R. Wang P. Radermacher O. McCook article RN13 Chronic psychosocial stress disturbs long-bone growth in adolescent mice Journal Article 2017 10.1242/dmm.030916 Dis Model Mech 10 1399-1409 12 https://www.ncbi.nlm.nih.gov/pubmed/28982680 S. Foertsch M. Haffner-Luntzer J. Kroner F. Gross K. Kaiser M. Erber S. O. Reber A. Ignatius article RN5 Complement C5a Functions as a Master Switch for the pH Balance in Neutrophils Exerting Fundamental Immunometabolic Effects Journal Article 2017 10.4049/jimmunol.1700393 J Immunol 198 4846-4854 12 https://www.ncbi.nlm.nih.gov/pubmed/28490576 S. Denk M. D. Neher D. A. C. Messerer R. Wiegner B. Nilsson D. Rittirsch K. Nilsson-Ekdahl S. Weckbach A. Ignatius M. Kalbitz F. Gebhard M. E. Weiss J. Vogt P. Radermacher J. Kohl J. D. Lambris M. S. Huber-Lang article RN48 Complement C5a-Induced Changes in Neutrophil Morphology During Inflammation Journal Article 2017 10.1111/sji.12580 Scand J Immunol 86 143-155 3 https://www.ncbi.nlm.nih.gov/pubmed/28671713 S. Denk R. P. Taylor R. Wiegner E. M. Cook M. A. Lindorfer K. Pfeiffer S. Paschke T. Eiseler M. Weiss E. Barth J. D. Lambris M. Kalbitz T. Martin H. Barth D. A. C. Messerer F. Gebhard M. S. Huber-Lang article RN6 Complement receptors C5aR1 and C5aR2 act differentially during the early immune response after bone fracture but are similarly involved in bone repair Journal Article 2017 10.1038/s41598-017-14444-3 Sci Rep 7 14061 1 https://www.ncbi.nlm.nih.gov/pubmed/29070810 A. Kovtun S. Bergdolt Y. Hagele R. Matthes J. D. Lambris M. Huber-Lang A. Ignatius article RN160 Complement-induced activation of MAPKs and Akt during sepsis: role in cardiac dysfunction Journal Article 2017 10.1096/fj.201700140R FASEB J 31 4129-4139 9 https://www.ncbi.nlm.nih.gov/pubmed/28572445 F. Fattahi M. Kalbitz E. A. Malan E. Abe L. Jajou M. S. Huber-Lang M. Bosmann M. W. Russell F. S. Zetoune P. A. Ward article RN285 Chloroquine derivatives block the translocation pores and inhibit cellular entry of Clostridium botulinum C2 toxin and Bacillus anthracis lethal toxin Journal Article 2017 10.1007/s00204-016-1716-9 Arch Toxicol 91 1431-1445 3 https://www.ncbi.nlm.nih.gov/pubmed/27106023 A. M. Kreidler R. Benz H. Barth article RN212 Early decreased TLR2 expression on monocytes is associated with their reduced phagocytic activity and impaired maturation in a porcine polytrauma model Journal Article 2017 10.1371/journal.pone.0187404 PLoS One 12 e0187404 11 https://www.ncbi.nlm.nih.gov/pubmed/29125848 L. Schimunek R. Serve M. P. J. Teuben P. Stormann B. Auner M. Woschek R. Pfeifer K. Horst T. P. Simon M. Kalbitz R. Sturm H. C. Pape F. Hildebrand I. Marzi B. Relja article RN152 Functional and Molecular Characterization of a Novel Traumatic Peripheral Nerve-Muscle Injury Model Journal Article 2017 10.1007/s12017-017-8450-1 Neuromolecular Med 19 357-374 2-3 https://www.ncbi.nlm.nih.gov/pubmed/28689354 R. Wanner M. Gey A. Abaei D. Warnecke L. Roy L. Dürselen V. Rasche B. Knöll article RN90 Hyperoxia or Therapeutic Hypothermia During Resuscitation from Non-Lethal Hemorrhagic Shock in Swine Journal Article 2017 10.1097/SHK.0000000000000884 Shock 48 564-570 5 https://www.ncbi.nlm.nih.gov/pubmed/28472012 B. L. Nussbaum T. Stenzel T. Merz A. Scheuerle O. McCook U. Wachter J. A. Vogt J. Matallo H. Gassler M. Gröger M. Matejovic E. Calzia L. Lampl M. Georgieff P. Möller P. Asfar P. Radermacher S. Häfner article RN22 Early structural changes of the heart after experimental polytrauma and hemorrhagic shock Journal Article 2017 10.1371/journal.pone.0187327 PLoS One 12 e0187327 10 https://www.ncbi.nlm.nih.gov/pubmed/29084268 C. K. Braun M. Kalbitz R. Halbgebauer P. Eisele D. A. C. Messerer S. Weckbach A. Schultze S. Braumuller F. Gebhard M. S. Huber-Lang article RN84 Hyperoxia and hypertonic saline in patients with septic shock (HYPERS2S): a two-by-two factorial, multicentre, randomised, clinical trial Journal Article 2017 10.1016/S2213-2600(17)30046-2 Lancet Respir Med 5 180-190 3 https://www.ncbi.nlm.nih.gov/pubmed/28219612 P. Asfar F. Schortgen J. Boisrame-Helms J. Charpentier E. Guerot B. Megarbane D. Grimaldi F. Grelon N. Anguel S. Lasocki M. Henry-Lagarrigue F. Gonzalez F. Legay C. Guitton M. Schenck J. M. Doise J. Devaquet T. Van Der Linden D. Chatellier J. P. Rigaud J. Dellamonica F. Tamion F. Meziani A. Mercat D. Dreyfuss V. Seegers P. Radermacher Hyper S. investigators Reva research network article RN45 Hsp70 facilitates trans-membrane transport of bacterial ADP-ribosylating toxins into the cytosol of mammalian cells Journal Article 2017 10.1038/s41598-017-02882-y Sci Rep 7 2724 1 https://www.ncbi.nlm.nih.gov/pubmed/28578412 K. Ernst J. Schmid M. Beck M. Hagele M. Hohwieler P. Hauff A. K. Uckert A. Anastasia M. Fauler T. Jank K. Aktories M. R. Popoff C. Schiene-Fischer A. Kleger M. Müller M. Frick H. Barth article RN240 Generic wound signals initiate regeneration in missing-tissue contexts Journal Article 2017 10.1038/s41467-017-02338-x Nat Commun 8 2282 1 https://www.ncbi.nlm.nih.gov/pubmed/29273738 S. Owlarn F. Klenner D. Schmidt F. Rabert A. Tomasso H. Reuter M. A. Mulaw S. Moritz L. Gentile G. Weidinger K. Bartscherer article RN185 Gaseous Mediators and Mitochondrial Function: The Future of Pharmacologically Induced Suspended Animation? Journal Article 2017 10.3389/fphys.2017.00691 Front Physiol 8 691 https://www.ncbi.nlm.nih.gov/pubmed/28974933 C. Hartmann B. Nussbaum E. Calzia P. Radermacher M. Wepler article RN179 Fifty Years of Research in ARDS. Gas Exchange in Acute Respiratory Distress Syndrome Journal Article 2017 10.1164/rccm.201610-2156SO Am J Respir Crit Care Med 196 964-984 8 https://www.ncbi.nlm.nih.gov/pubmed/28406724 P. Radermacher S. M. Maggiore A. Mercat article RN154 Experimental blunt chest trauma-induced myocardial inflammation and alteration of gap-junction protein connexin 43 Journal Article 2017 10.1371/journal.pone.0187270 PLoS One 12 e0187270 11 https://www.ncbi.nlm.nih.gov/pubmed/29121655 M. Kalbitz E. M. Amann B. Bosch A. Palmer A. Schultze J. Pressmar B. Weber M. Wepler F. Gebhard H. Schrezenmeier R. Brenner M. Huber-Lang article RN19 Evaluation of high-resolution In Vivo MRI for longitudinal analysis of endochondral fracture healing in mice Journal Article 2017 10.1371/journal.pone.0174283 PLoS One 12 e0174283 3 https://www.ncbi.nlm.nih.gov/pubmed/28333972 M. Haffner-Luntzer F. Muller-Graf R. Matthys Y. Hagele V. Fischer R. Jonas A. Abaei F. Gebhard V. Rasche A. Ignatius article RN83 Evaluation of gut-blood barrier dysfunction in various models of trauma, hemorrhagic shock, and burn injury Journal Article 2017 10.1097/TA.0000000000001654 J Trauma Acute Care Surg 83 944-953 5 https://www.ncbi.nlm.nih.gov/pubmed/28700414 L. Wrba A. Palmer C. K. Braun M. Huber-Lang article RN87 Effects of Hyperoxia During Resuscitation From Hemorrhagic Shock in Swine With Preexisting Coronary Artery Disease Journal Article 2017 10.1097/CCM.0000000000002767 Crit Care Med 45 e1270-e1279 12 https://www.ncbi.nlm.nih.gov/pubmed/29028763 C. Hartmann M. Loconte E. Antonucci M. Holzhauser T. Holle D. Katzsch T. Merz O. McCook U. Wachter J. A. Vogt A. Hoffmann M. Wepler M. Gröger M. Matejovic E. Calzia M. Georgieff P. Asfar P. Radermacher B. L. Nussbaum article RN102 Induction of Suppressor Cells and Increased Tumor Growth following Chronic Psychosocial Stress in Male Mice Journal Article 2016 10.1371/journal.pone.0159059 PLoS One 11 e0159059 7 https://www.ncbi.nlm.nih.gov/pubmed/27391954 D. Schmidt D. Peterlik S. O. Reber A. Lechner D. N. Mannel article RN189 Selepressin in Septic Shock: A Step Toward Decatecholaminization? Journal Article 2016 10.1097/CCM.0000000000001441 Crit Care Med 44 234-6 1 https://www.ncbi.nlm.nih.gov/pubmed/26672929 P. Asfar J. A. Russell J. Tuckermann P. Radermacher article RN14 Inhibition of Midkine Augments Osteoporotic Fracture Healing Journal Article 2016 10.1371/journal.pone.0159278 PLoS One 11 e0159278 7 http://www.ncbi.nlm.nih.gov/pubmed/27410432 M. Haffner-Luntzer J. Kemmler V. Heidler K. Prystaz T. Schinke M. Amling A. Kovtun A. E. Rapp A. Ignatius A. Liedert article RN117 Molecular Actions of Glucocorticoids in Cartilage and Bone During Health, Disease, and Steroid Therapy Journal Article 2016 10.1152/physrev.00011.2015 Physiol Rev 96 409-47 2 https://www.ncbi.nlm.nih.gov/pubmed/26842265 K. Hartmann M. Koenen S. Schauer S. Wittig-Blaich M. Ahmad U. Baschant J. P. Tuckermann article RN49 Protein Kinase D2 Assembles a Multiprotein Complex at the Trans-Golgi Network to Regulate Matrix Metalloproteinase Secretion Journal Article 2016 10.1074/jbc.M115.673582 J Biol Chem 291 462-77 1 https://www.ncbi.nlm.nih.gov/pubmed/26507660 T. Eiseler C. Wille C. Koehler A. Illing T. Seufferlein article RN33 Selective Localization of Shanks to VGLUT1-Positive Excitatory Synapses in the Mouse Hippocampus Journal Article 2016 10.3389/fncel.2016.00106 Front Cell Neurosci 10 106 https://www.ncbi.nlm.nih.gov/pubmed/27199660 C. Heise J. C. Schroeder M. Schoen S. Halbedl D. Reim S. Woelfle M. R. Kreutz M. J. Schmeisser T. M. Boeckers article RN186 Water-soluble allyl sulfones for dual site-specific labelling of proteins and cyclic peptides Journal Article 2016 10.1039/c6sc00005c Chem Sci 7 3234-3239 5 https://www.ncbi.nlm.nih.gov/pubmed/29997815 T. Wang A. Riegger M. Lamla S. Wiese P. Oeckl M. Otto Y. Wu S. Fischer H. Barth S. L. Kuan T. Weil article RN32 Shank3 is localized in axons and presynaptic specializations of developing hippocampal neurons and involved in the modulation of NMDA receptor levels at axon terminals Journal Article 2016 10.1111/jnc.13523 J Neurochem 137 26-32 1 https://www.ncbi.nlm.nih.gov/pubmed/26725465 S. Halbedl M. Schoen M. S. Feiler T. M. Boeckers M. J. Schmeisser article RN124 Spatially Resolved Genome-wide Transcriptional Profiling Identifies BMP Signaling as Essential Regulator of Zebrafish Cardiomyocyte Regeneration Journal Article 2016 10.1016/j.devcel.2015.12.010 Dev Cell 36 36-49 1 https://www.ncbi.nlm.nih.gov/pubmed/26748692 C. C. Wu F. Kruse M. D. Vasudevarao J. P. Junker D. C. Zebrowski K. Fischer E. S. Noel D. Grun E. Berezikov F. B. Engel A. Oudenaarden G. Weidinger J. Bakkers article RN139 Suppression of Neutrophil-Mediated Tissue Damage-A Novel Skill of Mesenchymal Stem Cells Journal Article 2016 10.1002/stem.2417 Stem Cells 34 2393-406 9 https://www.ncbi.nlm.nih.gov/pubmed/27299700 D. Jiang J. Muschhammer Y. Qi A. Kugler J. C. Vries M. Saffarzadeh A. Sindrilaru S. V. Beken M. Wlaschek M. A. Kluth C. Ganss N. Y. Frank M. H. Frank K. T. Preissner K. Scharffetter-Kochanek article RN3 The crucial role of neutrophil granulocytes in bone fracture healing Journal Article 2016 Eur Cell Mater 32 152-62 http://www.ncbi.nlm.nih.gov/pubmed/27452963 A. Kovtun S. Bergdolt R. Wiegner P. Radermacher M. Huber-Lang A. Ignatius article RN150 The multiple sclerosis drug fingolimod (FTY720) stimulates neuronal gene expression, axonal growth and regeneration Journal Article 2016 10.1016/j.expneurol.2016.03.012 Exp Neurol 279 243-260 https://www.ncbi.nlm.nih.gov/pubmed/26980486 S. Anastasiadou B. Knöll article RN121 Zebrafish fin and heart: what's special about regeneration? Journal Article 2016 10.1016/j.gde.2016.05.011 Curr Opin Genet Dev 40 48-56 https://www.ncbi.nlm.nih.gov/pubmed/27351724 I. M. Sehring C. Jahn G. Weidinger article RN73 GPR17 expressing NG2-Glia: Oligodendrocyte progenitors serving as a reserve pool after injury Journal Article 2016 10.1002/glia.22929 Glia 64 287-99 2 https://www.ncbi.nlm.nih.gov/pubmed/26464068 F. Vigano S. Schneider M. Cimino E. Bonfanti P. Gelosa L. Sironi M. P. Abbracchio L. Dimou article RN101 Immunization with a heat-killed preparation of the environmental bacterium Mycobacterium vaccae promotes stress resilience in mice Journal Article 2016 10.1073/pnas.1600324113 Proc Natl Acad Sci U S A 113 E3130-9 22 https://www.ncbi.nlm.nih.gov/pubmed/27185913 S. O. Reber P. H. Siebler N. C. Donner J. T. Morton D. G. Smith J. M. Kopelman K. R. Lowe K. J. Wheeler J. H. Fox Jr. Hassell B. N. Greenwood C. Jansch A. Lechner D. Schmidt N. Uschold-Schmidt A. M. Fuchsl D. Langgartner F. R. Walker M. W. Hale G. Lopez Perez W. Van Treuren A. Gonzalez A. L. Halweg-Edwards M. Fleshner C. L. Raison G. A. Rook S. D. Peddada R. Knight C. A. Lowry article RN67 Transplanted embryonic neurons integrate into adult neocortical circuits Journal Article 2016 10.1038/nature20113 Nature 539 248-253 7628 https://www.ncbi.nlm.nih.gov/pubmed/27783592 S. Falkner S. Grade L. Dimou K. K. Conzelmann T. Bonhoeffer M. Gotz M. Hubener article RN8 Fracture Healing Is Delayed in Immunodeficient NOD/scidIL2Rgammacnull Mice Journal Article 2016 10.1371/journal.pone.0147465 PLoS One 11 e0147465 2 http://www.ncbi.nlm.nih.gov/pubmed/26849055 A. E. Rapp R. Bindl S. Recknagel A. Erbacher I. Muller H. Schrezenmeier C. Ehrnthaller F. Gebhard A. Ignatius article RN18 C5aR inhibition in the early inflammatory phase does not affect bone regeneration in a model of uneventful fracture healing Journal Article 2016 10.1186/s40001-016-0236-7 Eur J Med Res 21 42 1 https://www.ncbi.nlm.nih.gov/pubmed/27784330 C. Ehrnthaller M. Huber-Lang A. Kovtun A. E. Rapp J. Kemmler F. Gebhard A. Ignatius article RN89 Effects of Hyperoxia and Mild Therapeutic Hypothermia During Resuscitation From Porcine Hemorrhagic Shock Journal Article 2016 10.1097/CCM.0000000000001412 Crit Care Med 44 e264-77 5 https://www.ncbi.nlm.nih.gov/pubmed/26588829 E. Knoller T. Stenzel F. Broeskamp R. Hornung A. Scheuerle O. McCook U. Wachter J. A. Vogt J. Matallo M. Wepler H. Gassler M. Gröger M. Matejovic E. Calzia L. Lampl M. Georgieff P. Möller P. Asfar P. Radermacher S. Häfner article RN127 A somitic contribution to the apical ectodermal ridge is essential for fin formation Journal Article 2016 10.1038/nature18953 Nature 535 542-6 7613 https://www.ncbi.nlm.nih.gov/pubmed/27437584 W. Masselink N. J. Cole F. Fenyes S. Berger C. Sonntag A. Wood P. D. Nguyen N. Cohen F. Knopf G. Weidinger T. E. Hall P. D. Currie article RN187 A Supramolecular Approach toward Bioinspired PAMAM-Dendronized Fusion Toxins Journal Article 2016 10.1002/mabi.201500417 Macromol Biosci 16 803-10 6 https://www.ncbi.nlm.nih.gov/pubmed/26833574 S. L. Kuan C. Förtsch D. Y. Ng S. Fischer Y. Tokura W. Liu Y. Wu K. Koynov H. Barth T. Weil article RN21 Antagonizing Midkine Accelerates Fracture Healing in Mice by Enhanced Bone Formation in the Fracture Callus Journal Article 2016 10.1111/bph.13503 Br J Pharmacol 173 2237-49 14 http://www.ncbi.nlm.nih.gov/pubmed/27111560 M. Haffner-Luntzer A. Heilmann A. E. Rapp R. Roessler T. Schinke M. Amling A. Ignatius A. Liedert article RN95 Astrocytic GluN2A and GluN2B Oppose the Synaptotoxic Effects of Amyloid-beta1-40 in Hippocampal Cells Journal Article 2016 10.3233/JAD-160297 J Alzheimers Dis 54 135-48 1 https://www.ncbi.nlm.nih.gov/pubmed/27497478 Y. Li L. Chang Y. Song X. Gao F. Roselli J. Liu W. Zhou Y. Fang W. Ling H. Li O. F. Almeida Y. Wu article RN149 Atf3 mutant mice show reduced axon regeneration and impaired regeneration-associated gene induction after peripheral nerve injury Journal Article 2016 10.1098/rsob.160091 Open Biol 6 8 https://www.ncbi.nlm.nih.gov/pubmed/27581653 M. Gey R. Wanner C. Schilling M. T. Pedro D. Sinske B. Knöll article RN28 Association of Kidney Tissue Barrier Disrupture and Renal Dysfunction in Resuscitated Murine Septic Shock Journal Article 2016 10.1097/SHK.0000000000000599 Shock 46 398-404 4 https://www.ncbi.nlm.nih.gov/pubmed/26926005 T. Stenzel C. Weidgang K. Wagner F. Wagner M. Gröger S. Weber B. Stahl U. Wachter J. Vogt E. Calzia S. Denk M. Georgieff M. Huber-Lang P. Radermacher O. McCook article RN29 Comparative Analysis of Novel Complement-Targeted Inhibitors, MiniFH, and the Natural Regulators Factor H and Factor H-like Protein 1 Reveal Functional Determinants of Complement Regulation Journal Article 2016 10.4049/jimmunol.1501919 J Immunol 196 866-76 2 https://www.ncbi.nlm.nih.gov/pubmed/26643478 M. J. Harder M. Anliker B. Hochsmann T. Simmet M. Huber-Lang H. Schrezenmeier D. Ricklin J. D. Lambris P. N. Barlow C. Q. Schmidt article RN27 Complement therapeutic strategies in trauma, hemorrhagic shock and systemic inflammation - closing Pandora's box? Journal Article 2016 10.1016/j.smim.2016.04.005 Semin Immunol 28 278-84 3 https://www.ncbi.nlm.nih.gov/pubmed/27157701 M. Huber-Lang F. Gebhard C. Q. Schmidt A. Palmer S. Denk R. Wiegner article RN157 Complement-induced activation of the cardiac NLRP3 inflammasome in sepsis Journal Article 2016 10.1096/fj.201600728R FASEB J 30 3997-4006 12 https://www.ncbi.nlm.nih.gov/pubmed/27543123 M. Kalbitz F. Fattahi J. J. Grailer L. Jajou E. A. Malan F. S. Zetoune M. Huber-Lang M. W. Russell P. A. Ward article RN55 Cortactin is a scaffolding platform for the E-cadherin adhesion complex and is regulated by protein kinase D1 phosphorylation Journal Article 2016 10.1242/jcs.184721 J Cell Sci 129 2416-29 12 https://www.ncbi.nlm.nih.gov/pubmed/27179075 R. Sroka J. Van Lint S. F. Katz M. R. Schneider A. Kleger S. Paschke T. Seufferlein T. Eiseler article RN69 Decrease in newly generated oligodendrocytes leads to motor dysfunctions and changed myelin structures that can be rescued by transplanted cells Journal Article 2016 10.1002/glia.23055 Glia 64 2201-2218 12 https://www.ncbi.nlm.nih.gov/pubmed/27615452 S. Schneider A. Gruart S. Grade Y. Zhang S. Kroger F. Kirchhoff G. Eichele J. M. Delgado Garcia L. Dimou article RN114 Dicer ablation in osteoblasts by Runx2 driven cre-loxP recombination affects bone integrity, but not glucocorticoid-induced suppression of bone formation Journal Article 2016 10.1038/srep32112 Sci Rep 6 32112 https://www.ncbi.nlm.nih.gov/pubmed/27554624 P. Liu M. Baumgart M. Groth J. Wittmann H. M. Jäck M. Platzer J. P. Tuckermann U. Baschant article RN158 Complement Destabilizes Cardiomyocyte Function In Vivo after Polymicrobial Sepsis and In Vitro Journal Article 2016 10.4049/jimmunol.1600091 J Immunol 197 2353-61 6 https://www.ncbi.nlm.nih.gov/pubmed/27521340 M. Kalbitz F. Fattahi T. J. Herron J. J. Grailer L. Jajou H. Lu M. Huber-Lang F. S. Zetoune J. V. Sarma S. M. Day M. W. Russell J. Jalife P. A. Ward article RN34 Dysfunctional cerebellar Purkinje cells contribute to autism-like behaviour in Shank2-deficient mice Journal Article 2016 10.1038/ncomms12627 Nat Commun 7 12627 https://www.ncbi.nlm.nih.gov/pubmed/27581745 S. Peter M. M. Ten Brinke J. Stedehouder C. M. Reinelt B. Wu H. Zhou K. Zhou H. J. Boele S. A. Kushner M. G. Lee M. J. Schmeisser T. M. Boeckers M. Schonewille F. E. Hoebeek C. I. De Zeeuw article RN42 Physiological and immune-biological characterization of a long-term murine model of blunt chest trauma Journal Article 2015 10.1097/SHK.0000000000000277 Shock 43 140-7 2 https://www.ncbi.nlm.nih.gov/pubmed/25526372 S. Häfner K. Wagner M. Wepler J. Matallo M. Gröger O. McCook A. Scheuerle M. Huber-Lang M. Frick S. Weber B. Stahl B. Jung E. Calzia M. Georgieff P. Möller P. Dietl P. Radermacher F. Wagner article RN96 Neddylation inhibition impairs spine development, destabilizes synapses and deteriorates cognition Journal Article 2015 10.1038/nn.3912 Nat Neurosci 18 239-51 2 https://www.ncbi.nlm.nih.gov/pubmed/25581363 A. M. Vogl M. M. Brockmann S. A. Giusti G. Maccarrone C. A. Vercelli C. A. Bauder J. S. Richter F. Roselli A. S. Hafner N. Dedic C. T. Wotjak D. M. Vogt-Weisenhorn D. Choquet C. W. Turck V. Stein J. M. Deussing D. Refojo article RN148 Neuronal expression of the transcription factor serum response factor modulates myelination in a mouse multiple sclerosis model Journal Article 2015 10.1002/glia.22794 Glia 63 958-76 6 https://www.ncbi.nlm.nih.gov/pubmed/25639799 S. Anastasiadou S. Liebenehm D. Sinske C. Reckendorf B. Moepps A. Nordheim B. Knöll article RN123 Use of the TetON System to Study Molecular Mechanisms of Zebrafish Regeneration Journal Article 2015 10.3791/52756 J Vis Exp e52756 100 https://www.ncbi.nlm.nih.gov/pubmed/26168286 D. Wehner C. Jahn G. Weidinger article RN159 Role of extracellular histones in the cardiomyopathy of sepsis Journal Article 2015 10.1096/fj.14-268730 FASEB J 29 2185-93 5 https://www.ncbi.nlm.nih.gov/pubmed/25681459 M. Kalbitz J. J. Grailer F. Fattahi L. Jajou T. J. Herron K. F. Campbell F. S. Zetoune M. Bosmann J. V. Sarma M. Huber-Lang F. Gebhard R. Loaiza H. H. Valdivia J. Jalife M. W. Russell P. A. Ward article RN35 Super-Resolution Microscopy Reveals Presynaptic Localization of the ALS/FTD Related Protein FUS in Hippocampal Neurons Journal Article 2015 10.3389/fncel.2015.00496 Front Cell Neurosci 9 496 https://www.ncbi.nlm.nih.gov/pubmed/26834559 M. Schoen J. M. Reichel M. Demestre S. Putz D. Deshpande C. Proepper S. Liebau M. J. Schmeisser A. C. Ludolph J. Michaelis T. M. Boeckers article RN85 Understanding the benefits and harms of oxygen therapy Journal Article 2015 10.1007/s00134-015-3670-z Intensive Care Med 41 1118-21 6 https://www.ncbi.nlm.nih.gov/pubmed/25634474 P. Asfar M. Singer P. Radermacher article RN192 Hyperoxia in intensive care, emergency, and peri-operative medicine: Dr. Jekyll or Mr. Hyde? A 2015 update Journal Article 2015 10.1186/s13613-015-0084-6 Ann Intensive Care 5 42 1 https://www.ncbi.nlm.nih.gov/pubmed/26585328 S. Häfner F. Beloncle A. Koch P. Radermacher P. Asfar article RN60 In vitro-generated MDSCs prevent murine GVHD by inducing type 2 T cells without disabling antitumor cytotoxicity Journal Article 2015 10.1182/blood-2015-01-624163 Blood 126 1138-48 9 https://www.ncbi.nlm.nih.gov/pubmed/26185131 J. J. Messmann T. Reisser F. Leithauser M. B. Lutz K. M. Debatin G. Strauss article RN145 Superoxide anion radicals induce IGF-1 resistance through concomitant activation of PTP1B and PTEN Journal Article 2015 10.15252/emmm.201404082 EMBO Mol Med 7 59-77 1 https://www.ncbi.nlm.nih.gov/pubmed/25520316 K. Singh P. Maity L. Krug P. Meyer N. Treiber T. Lucas A. Basu S. Kochanek M. Wlaschek H. Geiger K. Scharffetter-Kochanek article RN111 Glucocorticoids limit acute lung inflammation in concert with inflammatory stimuli by induction of SphK1 Journal Article 2015 10.1038/ncomms8796 Nat Commun 6 7796 https://www.ncbi.nlm.nih.gov/pubmed/26183376 S. Vettorazzi C. Bode L. Dejager L. Frappart E. Shelest C. Klassen A. Tasdogan H. M. Reichardt C. Libert M. Schneider F. Weih N. Henriette Uhlenhaut J. P. David M. Graler A. Kleiman J. P. Tuckermann article RN190 Gene expression levels of Casein kinase 1 (CK1) isoforms are correlated to adiponectin levels in adipose tissue of morbid obese patients and site-specific phosphorylation mediated by CK1 influences multimerization of adiponectin Journal Article 2015 10.1016/j.mce.2015.02.010 Mol Cell Endocrinol 406 87-101 C https://www.ncbi.nlm.nih.gov/pubmed/25724478 P. Xu P. Fischer-Posovszky J. Bischof P. Radermacher M. Wabitsch D. Henne-Bruns A. M. Wolf A. Hillenbrand U. Knippschild article RN4 Exposure to 100% Oxygen Abolishes the Impairment of Fracture Healing after Thoracic Trauma Journal Article 2015 10.1371/journal.pone.0131194 PLoS One 10 e0131194 7 http://www.ncbi.nlm.nih.gov/pubmed/26147725 J. Kemmler R. Bindl O. McCook F. Wagner M. Gröger K. Wagner A. Scheuerle P. Radermacher A. Ignatius article RN30 Early Detection of Junctional Adhesion Molecule-1 (JAM-1) in the Circulation after Experimental and Clinical Polytrauma Journal Article 2015 10.1155/2015/463950 Mediators Inflamm 2015 463950 https://www.ncbi.nlm.nih.gov/pubmed/26556956 S. Denk R. Wiegner F. M. Hones D. A. Messerer P. Radermacher M. Weiss M. Kalbitz C. Ehrnthaller S. Braumuller O. McCook F. Gebhard S. Weckbach M. Huber-Lang article RN194 Drug-Induced "Suspended Animation": Can a Dream Become True? Journal Article 2015 10.1097/CCM.0000000000000985 Crit Care Med 43 1528-30 7 https://www.ncbi.nlm.nih.gov/pubmed/26079228 P. Asfar P. Radermacher article RN193 Clostridial C3 Toxins Target Monocytes/Macrophages and Modulate Their Functions Journal Article 2015 10.3389/fimmu.2015.00339 Front Immunol 6 339 https://www.ncbi.nlm.nih.gov/pubmed/26175735 H. Barth S. Fischer A. Moglich C. Förtsch article RN98 Chronic subordinate colony housing paradigm: a mouse model to characterize the consequences of insufficient glucocorticoid signaling Journal Article 2015 10.3389/fpsyt.2015.00018 Front Psychiatry 6 18 https://www.ncbi.nlm.nih.gov/pubmed/25755645 D. Langgartner A. M. Fuchsl N. Uschold-Schmidt D. A. Slattery S. O. Reber article RN11 Blunt Chest Trauma in Mice after Cigarette Smoke-Exposure: Effects of Mechanical Ventilation with 100 % O2 Journal Article 2015 10.1371/journal.pone.0132810 PLoS One 10 e0132810 7 http://www.ncbi.nlm.nih.gov/pubmed/26225825 K. Wagner M. Gröger O. McCook A. Scheuerle P. Asfar B. Stahl M. Huber-Lang A. Ignatius B. Jung M. Duechs P. Möller M. Georgieff E. Calzia P. Radermacher F. Wagner article RN72 Astrocyte reactivity after brain injury-: The role of galectins 1 and 3 Journal Article 2015 10.1002/glia.22898 Glia 63 2340-61 12 https://www.ncbi.nlm.nih.gov/pubmed/26250529 S. Sirko M. Irmler S. Gascon S. Bek S. Schneider L. Dimou J. Obermann D. De Souza Paiva F. Poirier J. Beckers S. M. Hauck Y. A. Barde M. Gotz article RN142 ABCB5 Identifies Immunoregulatory Dermal Cells Journal Article 2015 10.1016/j.celrep.2015.08.010 Cell Rep 12 1564-74 10 https://www.ncbi.nlm.nih.gov/pubmed/26321644 T. Schatton J. Yang S. Kleffel M. Uehara S. R. Barthel C. Schlapbach Q. Zhan S. Dudeney H. Mueller N. Lee J. C. Vries B. Meier S. Vander Beken M. A. Kluth C. Ganss A. H. Sharpe A. M. Waaga-Gasser M. H. Sayegh R. Abdi K. Scharffetter-Kochanek G. F. Murphy T. S. Kupper N. Y. Frank M. H. Frank article RN62 Glucocorticoids attenuate acute graft-versus-host disease by suppressing the cytotoxic capacity of CD8(+) T cells Journal Article 2015 10.1002/path.4475 J Pathol 235 646-55 4 https://www.ncbi.nlm.nih.gov/pubmed/25358639 J. Theiss-Suennemann K. Jorss J. J. Messmann S. D. Reichardt E. Montes-Cobos F. Luhder J. P. Tuckermann A. Wolff H R. Dressel H. J. Grone G. Strauss H. M. Reichardt article RN161 S100A4 and uric acid promote mesenchymal stromal cell induction of IL-10+/IDO+ lymphocytes Journal Article 2014 10.4049/jimmunol.1303144 J Immunol 192 6102-10 12 https://www.ncbi.nlm.nih.gov/pubmed/24795458 J. L. Eisenbacher H. Schrezenmeier B. Jahrsdorfer C. Kaltenmeier M. T. Rojewski T. Yildiz T. Beyer A. Erle D. S. Wiegmann S. Grassl R. Hang S. Korper M. Wiesneth M. T. Lotze R. Lotfi article RN122 Wnt/beta-catenin signaling defines organizing centers that orchestrate growth and differentiation of the regenerating zebrafish caudal fin Journal Article 2014 10.1016/j.celrep.2013.12.036 Cell Rep 6 467-81 3 https://www.ncbi.nlm.nih.gov/pubmed/24485658 D. Wehner W. Cizelsky M. D. Vasudevaro G. Ozhan C. Haase B. Kagermeier-Schenk A. Roder R. I. Dorsky E. Moro F. Argenton M. Kuhl G. Weidinger article RN141 TSG-6 released from intradermally injected mesenchymal stem cells accelerates wound healing and reduces tissue fibrosis in murine full-thickness skin wounds Journal Article 2014 10.1038/jid.2013.328 J Invest Dermatol 134 526-537 2 https://www.ncbi.nlm.nih.gov/pubmed/23921952 Y. Qi D. Jiang A. Sindrilaru A. Stegemann S. Schatz N. Treiber M. Rojewski H. Schrezenmeier S. Vander Beken M. Wlaschek M. Bohm A. Seitz N. Scholz L. Dürselen J. Brinckmann A. Ignatius K. Scharffetter-Kochanek article RN61 TRAIL-receptor costimulation inhibits proximal TCR signaling and suppresses human T cell activation and proliferation Journal Article 2014 10.4049/jimmunol.1303242 J Immunol 193 4021-31 8 https://www.ncbi.nlm.nih.gov/pubmed/25217163 C. Lehnert M. Weiswange I. Jeremias C. Bayer M. Grunert K. M. Debatin G. Strauss article RN92 Effects of glycemic control on glucose utilization and mitochondrial respiration during resuscitated murine septic shock Journal Article 2014 10.1186/2197-425X-2-19 Intensive Care Med Exp 2 19 1 https://www.ncbi.nlm.nih.gov/pubmed/26266919 J. A. Vogt U. Wachter K. Wagner E. Calzia M. Gröger S. Weber B. Stahl M. Georgieff P. Asfar E. Fontaine P. Radermacher X. M. Leverve F. Wagner article RN15 Midkine-deficiency delays chondrogenesis during the early phase of fracture healing in mice Journal Article 2014 10.1371/journal.pone.0116282 PLoS One 9 e116282 12 https://www.ncbi.nlm.nih.gov/pubmed/25551381 M. Haffner-Luntzer A. Heilmann A. E. Rapp S. Beie T. Schinke M. Amling A. Ignatius A. Liedert article RN119 Mature osteoblasts dedifferentiate in response to traumatic bone injury in the zebrafish fin and skull Journal Article 2014 10.1242/dev.105817 Development 141 2225-34 11 https://www.ncbi.nlm.nih.gov/pubmed/24821985 K. Geurtzen F. Knopf D. Wehner L. F. Huitema S. Schulte-Merker G. Weidinger article RN12 H2S during circulatory shock: Some unresolved questions Journal Article 2014 10.1016/j.niox.2014.03.163 Nitric Oxide 41 48-61 http://www.ncbi.nlm.nih.gov/pubmed/24650697 O. McCook P. Radermacher C. Volani P. Asfar A. Ignatius J. Kemmler P. Möller C. Szabo M. Whiteman M. E. Wood R. Wang M. Georgieff U. Wachter article RN91 Dose-time dependency of hyperbaric hyperoxia-induced DNA strand breaks in human immune cells visualized with the comet assay Journal Article 2014 Undersea Hyperb Med 41 171-81 3 https://www.ncbi.nlm.nih.gov/pubmed/24984312 J. Witte W. Kahler T. Wunderlich P. Radermacher C. Wohlrab A. Koch article RN58 Recombinant CD95-Fc (APG101) prevents graft-versus-host disease in mice without disabling antitumor cytotoxicity and T-cell functions Journal Article 2013 10.1182/blood-2012-04-423392 Blood 121 556-65 3 https://www.ncbi.nlm.nih.gov/pubmed/23203823 N. Hartmann J. J. Messmann F. Leithauser M. Weiswange M. Kluge H. Fricke K. M. Debatin G. Strauss article RN63 TRAIL (TNF-related apoptosis-inducing ligand) regulates adipocyte metabolism by caspase-mediated cleavage of PPARgamma Journal Article 2013 10.1038/cddis.2012.212 Cell Death Dis 4 e474 https://www.ncbi.nlm.nih.gov/pubmed/23348588 M. Keuper I. Wernstedt Asterholm P. E. Scherer M. A. Westhoff P. Möller K. M. Debatin G. Strauss M. Wabitsch P. Fischer-Posovszky article RN147 The transcription factor serum response factor stimulates axon regeneration through cytoplasmic localization and cofilin interaction Journal Article 2013 10.1523/JNEUROSCI.3029-13.2013 J Neurosci 33 18836-48 48 https://www.ncbi.nlm.nih.gov/pubmed/24285890 S. Stern S. Haverkamp D. Sinske A. Tedeschi U. Naumann S. Di Giovanni S. Kochanek A. Nordheim B. Knöll article RN140 The effect of adipose tissue derived MSCs delivered by a chemically defined carrier on full-thickness cutaneous wound healing Journal Article 2013 10.1016/j.biomaterials.2012.12.014 Biomaterials 34 2501-15 10 https://www.ncbi.nlm.nih.gov/pubmed/23317813 D. Jiang Y. Qi N. G. Walker A. Sindrilaru A. Hainzl M. Wlaschek S. MacNeil K. Scharffetter-Kochanek article RN38 Sustained, neuron-specific IKK/NF-kappaB activation generates a selective neuroinflammatory response promoting local neurodegeneration with aging Journal Article 2013 10.1186/1750-1326-8-40 Mol Neurodegener 8 40 https://www.ncbi.nlm.nih.gov/pubmed/24119288 A. Maqbool M. Lattke T. Wirth B. Baumann article RN80 Multivariate determination of 13CO2/12CO2 ratios in exhaled mouse breath with mid-infrared hollow waveguide gas sensors Journal Article 2013 10.1007/s00216-013-6824-2 Anal Bioanal Chem 405 4945-51 14 https://www.ncbi.nlm.nih.gov/pubmed/23503745 F. Seichter A. Wilk K. Wörle S. S. Kim J. A. Vogt U. Wachter P. Radermacher B. Mizaikoff article RN71 Reactive glia in the injured brain acquire stem cell properties in response to sonic hedgehog. [corrected] Journal Article 2013 10.1016/j.stem.2013.01.019 Cell Stem Cell 12 426-39 4 https://www.ncbi.nlm.nih.gov/pubmed/23561443 S. Sirko G. Behrendt P. A. Johansson P. Tripathi M. Costa S. Bek C. Heinrich S. Tiedt D. Colak M. Dichgans I. R. Fischer N. Plesnila M. Staufenbiel C. Haass M. Snapyan A. Saghatelyan L. H. Tsai A. Fischer K. Grobe L. Dimou M. Gotz article RN97 Neuroprotection through excitability and mTOR required in ALS motoneurons to delay disease and extend survival Journal Article 2013 10.1016/j.neuron.2013.07.027 Neuron 80 80-96 1 https://www.ncbi.nlm.nih.gov/pubmed/24094105 S. Saxena F. Roselli K. Singh K. Leptien J. P. Julien F. Gros-Louis P. Caroni article RN64 Live imaging of astrocyte responses to acute injury reveals selective juxtavascular proliferation Journal Article 2013 10.1038/nn.3371 Nat Neurosci 16 580-6 5 https://www.ncbi.nlm.nih.gov/pubmed/23542688 S. Bardehle M. Kruger F. Buggenthin J. Schwausch J. Ninkovic H. Clevers H. J. Snippert F. J. Theis M. Meyer-Luehmann I. Bechmann L. Dimou M. Gotz article RN144 Disclosure of the Culprits: Macrophages-Versatile Regulators of Wound Healing Journal Article 2013 10.1089/wound.2012.0407 Adv Wound Care (New Rochelle) 2 357-368 7 https://www.ncbi.nlm.nih.gov/pubmed/24587973 A. Sindrilaru K. Scharffetter-Kochanek article RN125 Notch signaling coordinates cellular proliferation with differentiation during zebrafish fin regeneration Journal Article 2013 10.1242/dev.087452 Development 140 1412-23 7 https://www.ncbi.nlm.nih.gov/pubmed/23462472 B. Grotek D. Wehner G. Weidinger article RN110 Glucocorticoid receptor dimerization is required for survival in septic shock via suppression of interleukin-1 in macrophages Journal Article 2012 10.1096/fj.11-192112 FASEB J 26 722-9 2 https://www.ncbi.nlm.nih.gov/pubmed/22042221 A. Kleiman S. Hübner J. M. Rodriguez Parkitna A. Neumann S. Hofer M. A. Weigand M. Bauer W. Schmid G. Schutz C. Libert H. M. Reichardt J. P. Tuckermann article RN39 IkappaB kinase/nuclear factor kappaB-dependent insulin-like growth factor 2 (Igf2) expression regulates synapse formation and spine maturation via Igf2 receptor signaling Journal Article 2012 10.1523/JNEUROSCI.0111-12.2012 J Neurosci 32 5688-703 16 https://www.ncbi.nlm.nih.gov/pubmed/22514330 M. J. Schmeisser B. Baumann S. Johannsen G. F. Vindedal V. Jensen O. C. Hvalby R. Sprengel J. Seither A. Maqbool A. Magnutzki M. Lattke F. Oswald T. M. Boeckers T. Wirth article RN31 Early complementopathy after multiple injuries in humans Journal Article 2012 10.1097/SHK.0b013e3182471795 Shock 37 348-54 4 https://www.ncbi.nlm.nih.gov/pubmed/22258234 A. M. Burk M. Martin M. A. Flierl D. Rittirsch M. Helm L. Lampl U. Bruckner G. L. Stahl A. M. Blom M. Perl F. Gebhard M. Huber-Lang article RN86 Bladder tissue oxygen tension monitoring in pigs subjected to a range of cardiorespiratory and pharmacological challenges Journal Article 2012 10.1007/s00134-012-2712-z Intensive Care Med 38 1868-76 11 https://www.ncbi.nlm.nih.gov/pubmed/23052956 A. Dyson F. Simon A. Seifritz O. Zimmerling J. Matallo E. Calzia P. Radermacher M. Singer article RN153 Alteration of complement hemolytic activity in different trauma and sepsis models Journal Article 2012 10.2147/JIR.S31787 J Inflamm Res 5 59-66 https://www.ncbi.nlm.nih.gov/pubmed/22879778 C. Ehrnthaller U. Amara S. Weckbach M. Kalbitz M. Huber-Lang S. Bahrami article RN143 An unrestrained proinflammatory M1 macrophage population induced by iron impairs wound healing in humans and mice Journal Article 2011 10.1172/JCI44490 J Clin Invest 121 985-97 3 https://www.ncbi.nlm.nih.gov/pubmed/21317534 A. Sindrilaru T. Peters S. Wieschalka C. Baican A. Baican H. Peter A. Hainzl S. Schatz Y. Qi A. Schlecht J. M. Weiss M. Wlaschek C. Sunderkotter K. Scharffetter-Kochanek article RN120 Bone regenerates via dedifferentiation of osteoblasts in the zebrafish fin Journal Article 2011 10.1016/j.devcel.2011.04.014 Dev Cell 20 713-24 5 https://www.ncbi.nlm.nih.gov/pubmed/21571227 F. Knopf C. Hammond A. Chekuru T. Kurth S. Hans C. W. Weber G. Mahatma S. Fisher M. Brand S. Schulte-Merker G. Weidinger article RN131 Imaging hematopoietic stem cells in the marrow of long bones in vivo Journal Article 2011 10.1007/978-1-61779-145-1_15 Methods Mol Biol 750 215-24 https://www.ncbi.nlm.nih.gov/pubmed/21618094 A. Kohler H. Geiger M. Gunzer article RN70 Progenitors in the adult cerebral cortex: cell cycle properties and regulation by physiological stimuli and injury Journal Article 2011 10.1002/glia.21156 Glia 59 869-81 6 https://www.ncbi.nlm.nih.gov/pubmed/21446038 C. Simon M. Gotz L. Dimou article RN133 R-Ras and Rac GTPase cross-talk regulates hematopoietic progenitor cell migration, homing, and mobilization Journal Article 2011 10.1074/jbc.M111.226951 J Biol Chem 286 24068-78 27 https://www.ncbi.nlm.nih.gov/pubmed/21572048 X. Shang J. A. Cancelas L. Li F. Guo W. Liu J. F. Johnson A. Ficker D. Daria H. Geiger N. Ratner Y. Zheng article RN65 The GPR17 receptor in NG2 expressing cells: focus on in vivo cell maturation and participation in acute trauma and chronic damage Journal Article 2011 10.1002/glia.21237 Glia 59 1958-73 12 https://www.ncbi.nlm.nih.gov/pubmed/21956849 E. Boda F. Vigano P. Rosa M. Fumagalli V. Labat-Gest F. Tempia M. P. Abbracchio L. Dimou A. Buffo article RN163 Cardiac and metabolic effects of hypothermia and inhaled hydrogen sulfide in anesthetized and ventilated mice Journal Article 2010 10.1097/ccm.0b013e3181b9ed2e Crit Care Med 38 588-95 2 https://www.ncbi.nlm.nih.gov/pubmed/20095069 K. Baumgart F. Wagner M. Gröger S. Weber E. Barth J. A. Vogt U. Wachter M. Huber-Lang M. W. Knoferl G. Albuszies M. Georgieff P. Asfar C. Szabo E. Calzia P. Radermacher V. Simkova article RN132 Pharmacological inhibition of EGFR signaling enhances G-CSF-induced hematopoietic stem cell mobilization Journal Article 2010 10.1038/nm.2217 Nat Med 16 1141-6 10 https://www.ncbi.nlm.nih.gov/pubmed/20871610 M. A. Ryan K. J. Nattamai E. Xing D. Schleimer D. Daria A. Sengupta A. Kohler W. Liu M. Gunzer M. Jansen N. Ratner T. D. Le Cras A. Waterstrat G. Van Zant J. A. Cancelas Y. Zheng H. Geiger