Clarissa READ (Villinger)

2023

  • Kund J, Kruse J-H, Gruber A, Trentin I, Langer M, Read C, Neusser G, Blaimer D, Rupp U, Streb C, Leopold K, Schacher FH, Kranz C (2023) Multimodale Analyse lichtinduzierter Wasseroxidation in nanoporösen Blockcopolymer-Membranen**. Angewandte Chemie 135(22):e202217196. https://doi.org/10.1002/ange.202217196
  • Kund J, Kruse J-H, Gruber A, Trentin I, Langer M, Read C, Neusser G, Blaimer D, Rupp U, Streb C, Leopold K, Schacher FH, Kranz C (2023) Multimodal Analysis of Light-Driven Water Oxidation in Nanoporous Block Copolymer Membranes**. Angewandte Chemie International Edition 62(22):e202217196. https://doi.org/10.1002/anie.202217196
  • Hirschenberger M, Lepelley A, Rupp U, Klute S, Hunszinger V, Koepke L, Merold V, Didry-Barca B, Wondany F, Bergner T, Wiese S, Volpi S, Gattorno M, Papa R, Lynch S-A, Haug MG, Houge G, Wigby KM, Sprague J, Lenberg J, Read C, Walther P, Michaelis J, Kirchhoff F, Mann CC de O, Crow YJ, Sparrer KMJ (2023) ARF1 prevents aberrant type I IFN induction by regulating STING activation and recycling. Nat Commun 14, 6770 (2023). https://doi.org/10.1038/s41467-023-42150-4
  • Olari L-R, Bauer R, Gil Miró M, Vogel V, Cortez Rayas L, Groß R, Gilg A, Klevesath R, Rodríguez Alfonso AA, Kaygisiz K, Rupp U, Pant P, Mieres-Pérez J, Steppe L, Schäffer R, Rauch-Wirth L, Conzelmann C, Müller JA, Zech F, Gerbl F, Bleher J, Preising N, Ständker L, Wiese S, Thal DR, Haupt C, Jonker HRA, Wagner M, Sanchez-Garcia E, Weil T, Stenger S, Fändrich M, von Einem J, Read C, Walther P, Kirchhoff F, Spellerberg B, Münch J (2023) The C-terminal 32-mer fragment of hemoglobin alpha is an amyloidogenic peptide with antimicrobial properties. Cell Mol Life Sci 80(6):151. https://doi.org/10.1007/s00018-023-04795-8
  • Read C, Bergner T (2023) Wie beobachtet man Viren bei ihrem Zusammenbau? Biospektrum 29, 589–591. https://doi.org/10.1007/s12268-023-2028-2

2022

  • Schauflinger M, Bergner T, Neusser G, Kranz C, Read C (2022) Potassium permanganate is an excellent alternative to osmium tetroxide in freeze-substitution. Histochem Cell Biol 157(4):481–489. https://doi.org/10.1007/s00418-021-02070-0
  • Scherer M, Read C, Neusser G, Kranz C, Kuderna AK, Müller R, Full F, Wörz S, Reichel A, Schilling E-M, Walther P, Stamminger T (2022) Dual signaling via interferon and DNA damage response elicits entrapment by giant PML nuclear bodies. eLife 11:e73006. https://doi.org/10.7554/eLife.73006
  • Shaga Devan K, Kestler HA, Read C, Walther P (2022) Weighted average ensemble-based semantic segmentation in biological electron microscopy images. Histochem Cell Biol 158(5):447–462. https://doi.org/10.1007/s00418-022-02148-3
  • Weil T, Kirupakaran A, Le M-H, Rebmann P, Mieres-Perez J, Issmail L, Conzelmann C, Müller JA, Rauch L, Gilg A, Wettstein L, Groß R, Read C, Bergner T, Pålsson SA, Uhlig N, Eberlein V, Wöll H, Klärner F-G, Stenger S, Kümmerer BM, Streeck H, Fois G, Frick M, Braubach P, Spetz A-L, Grunwald T, Shorter J, Sanchez-Garcia E, Schrader T, Münch J (2022) Advanced Molecular Tweezers with Lipid Anchors against SARS-CoV-2 and Other Respiratory Viruses. JACS Au 2(9):2187–2202. https://doi.org/10.1021/jacsau.2c00220
  • Zech F, Weber S, Dietenberger H, Zhang L, Noettger S, Volcic M, Bergner T, Read C, Sparrer KMJ, Barth TFE, Kirchhoff F (2023) SARS-CoV-2 inhibition and specific targeting of infected cells by VSV particles carrying the ACE2 receptor. Sig Transduct Target Ther 8(1):1–4. https://doi.org/10.1038/s41392-023-01492-7
  • Kniesel H, Ropinski T, Bergner T, Devan KS, Read C, Walther P, Ritschel T, Hermosilla P (2022) Clean Implicit 3D Structure From Noisy 2D STEM Images. pp 20762–20772
  • Bergner T, Zech F, Hirschenberger M, Stenger S, Sparrer KMJ, Kirchhoff F, Read C (2022) Near-Native Visualization of SARS-CoV-2 Induced Membrane Remodeling and Virion Morphogenesis. Viruses 14(12):2786. https://doi.org/10.3390/v14122786

2021

  • König P, Svrlanska A, Read C, Feichtinger S, Stamminger T (2021) The Autophagy-Initiating Protein Kinase ULK1 Phosphorylates Human Cytomegalovirus Tegument Protein pp28 and Regulates Efficient Virus Release. J Virol 95(6):e02346-20. https://doi.org/10.1128/JVI.02346-20
  • Müller JA, Groß R, Conzelmann C, Krüger J, Merle U, Steinhart J, Weil T, Koepke L, Bozzo CP, Read C, Fois G, Eiseler T, Gehrmann J, van Vuuren J, Wessbecher IM, Frick M, Costa IG, Breunig M, Grüner B, Peters L, Schuster M, Liebau S, Seufferlein T, Stenger S, Stenzinger A, MacDonald PE, Kirchhoff F, Sparrer KMJ, Walther P, Lickert H, Barth TFE, Wagner M, Münch J, Heller S, Kleger A (2021) SARS-CoV-2 infects and replicates in cells of the human endocrine and exocrine pancreas. Nat Metab 3(2):149–165. https://doi.org/10.1038/s42255-021-00347-1
  • Read C, Walther P, von Einem J (2021) Quantitative Electron Microscopy to Study HCMV Morphogenesis. In: Yurochko AD (ed) Human Cytomegaloviruses: Methods and Protocols. Springer US, New York, NY, pp 265–289
  • Brenner S, Braun B, Read C, Weil T, Walther P, Schrader T, Münch J, von Einem J (2021) The Molecular Tweezer CLR01 Inhibits Antibody-Resistant Cell-to-Cell Spread of Human Cytomegalovirus. Viruses 13(9):1685. https://doi.org/10.3390/v13091685
  • Devan KS, Walther P, Einem J von, Ropinski T, Kestler HA, Read C (2021) Improved automatic detection of herpesvirus secondary envelopment stages in electron microscopy by augmenting training data with synthetic labelled images generated by a generative adversarial network. Cellular Microbiology 23(2):e13280. https://doi.org/10.1111/cmi.13280
  • Schütz D, Read C, Groß R, Röcker A, Rode S, Annamalai K, Fändrich M, Münch J (2021) Negatively Charged Peptide Nanofibrils from Immunoglobulin Light Chain Sequester Viral Particles but Lack Cell-Binding and Viral Transduction-Enhancing Properties. ACS Omega 6(11):7731–7738. https://doi.org/10.1021/acsomega.1c00068
  • Schütz D, Rode S, Read C, Müller JA, Glocker B, Sparrer KMJ, Fackler OT, Walther P, Münch J (2021) Viral Transduction Enhancing Effect of EF-C Peptide Nanofibrils Is Mediated by Cellular Protrusions. Advanced Functional Materials n/a(n/a):2104814. https://doi.org/10.1002/adfm.202104814

2020

  • Weil T, Groß R, Röcker A, Bravo-Rodriguez K, Heid C, Sowislok A, Le M-H, Erwin N, Dwivedi M, Bart SM, Bates P, Wettstein L, Müller JA, Harms M, Sparrer K, Ruiz-Blanco YB, Stürzel CM, von Einem J, Lippold S, Read C, Walther P, Hebel M, Kreppel F, Klärner F-G, Bitan G, Ehrmann M, Weil T, Winter R, Schrader T, Shorter J, Sanchez-Garcia E, Münch J (2020) Supramolecular Mechanism of Viral Envelope Disruption by Molecular Tweezers. J Am Chem Soc 142(40):17024–17038. https://doi.org/10.1021/jacs.0c06400

2019

  • Read C, Schauflinger M, Nikolaenko D, Walther P, Einem J von (2019) Regulation of human cytomegalovirus secondary envelopment by a C-terminal tetra-lysine motif in pUL71. Journal of Virology :JVI.02244-18. https://doi.org/10.1128/JVI.02244-18
  • Shaga-Devan K, Walther P, von Einem J, Ropinski T, Kestler HA, Read C (2019) Detection of herpesvirus capsids in transmission electron microscopy images using transfer learning. Histochem Cell Biol 151(2):101–114. https://doi.org/10.1007/s00418-018-1759-5
  • Zhang H, Read C, Nguyen CC, Siddiquey MNA, Shang C, Hall CM, von Einem J, Kamil JP (2019) The Human Cytomegalovirus Nonstructural Glycoprotein UL148 Reorganizes the Endoplasmic Reticulum. mBio 10(6):e02110-19, /mbio/10/6/mBio.02110-19.atom. https://doi.org/10.1128/mBio.02110-19

2018

  • Dietz AN, Villinger C, Becker S, Frick M, von Einem J (2018) A Tyrosine-Based Trafficking Motif of the Tegument Protein pUL71 Is Crucial for Human Cytomegalovirus Secondary Envelopment. Journal of virology 92(1). https://doi.org/10.1128/jvi.00907-17
  • Yin X, Ziegler A, Kelm K, Hoffmann R, Watermeyer P, Alexa P, Villinger C, Rupp U, Schlüter L, Reusch TBH, Griesshaber E, Walther P, Schmahl WW (2018) Formation and mosaicity of coccolith segment calcite of the marine algae Emiliania huxleyi. Journal of phycology 54(1):85—104. https://doi.org/10.1111/jpy.12604

2017

  • Maier AK, Jung R, Villinger C, Schubert A, Walther P, Sinzger C, Lieber D (2017) A Luciferase Gene Driven by an Alphaherpesviral Promoter Also Responds to Immediate Early Antigens of the Betaherpesvirus HCMV, Allowing Comparative Analyses of Different Human Herpesviruses in One Reporter Cell Line. PLoS ONE 12(1):e0169580. https://doi.org/10.1371/journal.pone.0169580

2016

2015

  • Villinger C, Neusser G, Kranz C, Walther P, Mertens T (2015) 3D Analysis of HCMV Induced-Nuclear Membrane Structures by FIB/SEM Tomography: Insight Into an Unprecedented Membrane Morphology. Viruses 7(11):5686–5704. https://doi.org/10.3390/v7112900
  • Cappadona I, Villinger C, Schutzius G, Mertens T, von Einem J (2015) Human Cytomegalovirus pUL47 Modulates Tegumentation and Capsid Accumulation at the Viral Assembly Complex. J Virol 89(14):7314–7328.https://doi.org/10.1128/JVI.00603-15

2014

  • Villinger C, Schauflinger M, Gregorius H, Kranz C, Höhn K, Nafeey S, Walther P (2014) Three-Dimensional Imaging of Adherent Cells using FIB/SEM and STEM. In: Kuo J (ed) Electron Microscopy. Humana Press, Totowa, NJ, pp 617–638

2013

  • Schauflinger M, Villinger C, Mertens T, Walther P, von Einem J (2013) Analysis of Human Cytomegalovirus Secondary Envelopment by Advanced Electron Microscopy: HCMV Morphogenesis. Cellular Microbiology 15(2):305–314. https://doi.org/10.1111/cmi.12077
  • Schauflinger M, Villinger C, Walther P (2013) Three-dimensional visualization of virus-infected cells by serial sectioning: an electron microscopic study using resin embedded cells. In: Bailer S, Lieber D (eds) Virus-Host Interactions. Methods in Molecular Biology (Methods and Protocols). Humana Press, Totowa, NJ, pp 227–237

2012

  • Villinger C, Gregorius H, Kranz C, Höhn K, Münzberg C, Wichert G, Mizaikoff B, Wanner G, Walther P (2012) FIB/SEM Tomography with TEM-like Resolution for 3D Imaging of High-pressure Frozen Cells. Histochemistry and Cell Biology 138(4):549–556. https://doi.org/10.1007/s00418-012-1020-6