 
							
					
			
	
						
					
				 
							
					
			
	
						
					
				23.-25.06.2024
SFB 1074 Retreat - Grand Hotel Dino (Lago Maggiore Italy)
After 12 successful years, we all came together to celebrate the end of our SFB 1074. It was a bittersweet moment filled with updates of all the projects, meetings and scientific exchanges, meals and lots of laughter under the italian sun!
18.04.2024
Speaker: Prof. Bernhard Gentner
 Ludwig Institute for Cancer Research Lausanne
 Lausanne, Switzerland
Title: Single cell analysis of normal and malignant hematopoietic stem cells
 
 Location: Seminar Room 2609/10, Internal Medicine
 Time: 16:30 - 17:30
 Hosts: Prof. Lüder Meyer
 Department of Pediatrics and Adolescent Medicine
 
 Announcement
 
							
					
			
	
						
					
							14.03.2024
Speaker: Prof. Paul Bourgine
 Lund University, Lund, Sweden
Title: Engineering human bone Marrow niches for disease modeling
 
 Location: Seminar Room 2609/10, Internal Medicine
 Time: 16:30 - 17:30
 Hosts: Prof. Hartmut Geiger
 Institute for Molecular Biology
 
 Announcement
 
							
					
			
	
						
					
							07.03.2024
Speaker: Dr. Gabriele Casirati
 Dana-Farber Institute / Boston Children's Cancer and Blood Disorder Center
 Boston, MA, USA
Title: Epitope editing to enable targeted immunotherapy of Acute Myeloid Leukemia
 
 Location: Seminar Room 2609/10, Internal Medicine
 Time: 16:30 - 17:30
 Hosts: Prof. Hartmut Döhner & Dr. Elisa Sala
 Department of Internal Medicine III
 
 Announcement
 
							
					
			
	
						
					
							15.02.2024
Speaker: Prof. Dr. Mascha Binder
 Universitätsspital Basel
Title: The antigen receptor as targe for cellular therapies in lymphomas
 
 Location: Seminar Room 2609/10, Internal Medicine
 Time: 16:30 - 17:30
 Hosts: Prof. Dr. Hassan Jumaa
 Institute for Immunology
 
 Announcement
 
							
					
			
	
						
					
							18.01.2024
Speaker: Prof. Victor Tybulewicz
 The Francis Crick Institute, London, UK
Title: Critical Roles for Ion and Water Flux in B and T cell migration and activation
 
 Location: Seminar Room 2609/10, Internal Medicine
 Time: 16:30 - 17:30
 Hosts: Dr. Elias Hobeika
 Institute for Immunology
 
 Announcement
 
							
					
			
	
						
					
							16.11.2023
Speaker: Dr. Jérome Paggetti
 Luxembourg Institute of Health
Title: Chronic lymphocytic leukemia, microenvironment, and novel therapies
 
 Location: Seminar Room 2611, Internal Medicine
 Time: 16:30 - 17:30
 Hosts: Dr. Billy Jebaraj and Prof. Stephan Stilgenbauer
 Deparment of Internal Medicine III and Comprehensive Cancer Center Ulm
 
 Announcement
 
							
					
			
	
						
					
							19.10.2023
Speaker: Dr. Christian Braun
 Haunersches Kinderspital, LMU München
Title: Targeting dysegulated transcription programs in cancer
 
 Location: Seminar Room 2609/10, Internal Medicine
 Time: 16:30 - 17:30
 Host: Prof. Lüder Meyer, Klinik für Kinder- und Jugendmedizin
 
 Announcement
28.09.2023
Speaker: Dr. Meike Vogler
 Kinderkrebsstiftung Frankfurt
Title: Targeting apoptosis signalling in pediatric cancer
 
 Location: TTU Hörsaal
 Time: 16:30 - 17:30
 Host: Prof. Klaus-Michael Debatin, Klinik für Kinder- und Jugendmedizin
 
 Announcement
 
							
					
			
	
						
					
							20.07.2023
Speaker: Dr. Megan S. Lim
 Memorial Sloan Kettering Cancer Center
 New York, USA
Title: Integrated genomic and proteomic approaches reveal novel biologic insights in fusion kinase-driven anaplastic large cell lymphoma
 
 Location: Seminar Room 2609/10, Internal Medicine
 Time: 16:30 - 17:30
 Host: Prof. Reiner Siebert, Institute of Human Genetics
 
 Announcement
 
							
					
			
	
						
					
							15.06.2023
Speaker: Prof. Arndt Borkhardt
 Universitätsklinikum Düsseldorf
Title: Towards prevention of childhood ALL
 
 Location: Seminar Room 2609/10, Internal Medicine
 Time: 16:30 - 17:30
 Host: Prof. Klaus-Michael Debatin, Klinik für Kinder- und Jugendmedizin
 
 Announcement
 
							
					
			
	
						
					
							11.05.2023
Speaker: PD Dr. Niklas Gebauer
 Universitätsklinikum Schleswig-Holstein, Lübeck, Germany
Title: Blastic plasmacytoid dentritic cell neoplasm through the eyes of a precision oncologist - a multi-omics approach
 
 Location: Seminar Room 2609/10, Internal Medicine
 Time: 17:00 - 18:00
 Host: Prof. Reiner Siebert, Institute of Human Genetics
 
 Announcement
 
							
					
			
	
						
					
							20.04.2023
Speaker: Vera Martins, PhD
 Instituto Gulbenkian de Ciência, Oeiras, Portugal
Title: Establishing thymic cell competition following bone marrow correction of yc-deficiency is required to prevent T-cell acute lymphoblastic leukemia
 
 Location: Seminar Room 2609/10, Internal Medicine
 Time: 16:30 - 17:30
 Host: Prof. Klaus-Michael Debatin, Department of Pediatrics and Adolescent Medicine
 
 Announcement
 
							
					
			
	
						
					
							16.02.2023
Speaker: Prof. Laurence de Leval
 Institut Universitaire de Pathologie, Lausanne, Switzerland
Title: Insights into the molecular pathogenesis of T-cell lymphomas
 
 Location: Seminar Room 2622, Internal Medicine
 Time: 16:30 - 17:30
 Host: Prof. Reiner Siebert, Institute of Human Genetics
 
 Announcement
 
							
					
			
	
						
					
							26.01.2023
Speaker: Rushad Pavri, PhD
 Research Institute of Molecular Pathology (IMP), Vienna, Austria
Title: DNA replication timing in the biogenesis of lymphomagenic translocations in B cells
 
 Location: Multimedia Room 2.059, Building N27
 Time: 17:00 - 18:00
 Host: Prof. Hassan Jumaa and Dr. Elias Hobeika (Institute of Molecular Medicine)
 
 Announcement
 
							
					
			
	
						
					
							27.10.2022
Speaker: Eleni Papanikolaou, PhD
 Miltenyi Biotec B.V. Co. KG, Bergisch-Gladbach
 Nationaland Kapodistrian University of Athens, Greece
Title: Genetic therapies of blood diseases in the horizon
 
 Location: Room 2609/10 (Medical Building)
 Time: 17:00 - 18:00
 Host: Prof. Hartmut Geiger (Institute of Molecular Medicine)
 
 Announcement
 
							
					
			
	
						
					
							11.10.2022
Speaker: Nicoletta Cieri
 Dana-Farber Cancer Institute, Boston, MA (USA)
Title: Systematic identification of minor histocompatibility antigens to address GVHD and GVL
 
 Location: Room 2609/10 (Medical Building)
 Time: 17:00 - 18:00
 Host: Prof. Hartmut Döhner (Department of Internal Medicine III)
 
 Announcement
10.10.2019
Speaker: Prof. Georg Holländer
 University of Basel, Switzerland and University of Oxford, UK
Title: The rise-and-fall of the thymus: Molecular and cellular insight
 
 Location: Room 2609/10 (Medical Building)
 Time: 17:00 - 18:00
 Host: Dr. Elias Hobeika & Prof. Hassan Jumaa (Institute of Immunology)
 
 Announcement
18.07.2019
Speaker: Prof. Ursula Klingmüller
German Cancer Research Center (DKFZ), Heidelberg, Germany
Title: A systems biology approach to the regulation of erythropoiesis and towards application in erythroleukemia
Location: Room 2609/10 (Medical Building)
Time: 17:00 - 18:00
Host: Prof. Michaela Feuring-Buske (Innere Medizin III)
Announcement
 
							
					
			
	
						
					
							11.07.2019
Speaker: Prof. Ulf Klein
 St. James' University Hospital, University of Leeds, UK
 
 Title: The germinal center B-cell reaction: physiology and disruption in malignancy
 
 Location: Room 2609/10 (Medical Building)
 Time: 17:00 - 18:00
 Host: Prof. Hassan Jummaa (Institute of Immunology)
 
 Announcement
 
							
					
			
	
						
					
							04.04.2019
Mini-Symposium
Speakers: 
Dr. Lorenzo Brunetti
University of Perugia, Italy
Title: New insights into the biology of acute myeloid leukemia with mutated NPM1
Dr. Stefano Indraccolo
Istituto Oncologico Veneto - IRCCS, Padova, Italy
Title: Dissecting molecular mechanisms of resistance to Notch1-targeted therapy int-cell acute lymphoblastic leukemia xenografts
Location: Room 2609/10 (Medical Building)
Time: 17:00 - 18:00
Hosts: Dr. Jan Krönke (Internal Medicine III) & Prof. Lüder Hinrich Meyer (Dept. of Pediatrics and Adolescent Medicine)
21.03.2019
Speaker: Prof. Roland Schmitz
University of Duisburg-Essen
Title: Genetics of aggressive B-cell lymphoma: Implications for precision medicine
Location: Room 2609/10 (Medical Building)
Time: 17:00 - 18:00
Host: Prof. Reiner Siebert (Institute of Human Genetics)
Announcement
24.01.2019
Speaker: Prof. Ralf Küppers
University of Duisburg-Essen, Medical School
Title: Mechanisms of lymphoma pathogenesis
Location: Room 2609/10 (Medical Building)
Time: 16:00 - 17:00
Host: Prof. Reiner Siebert & Dr. Rabea Wagener
 
							
					
			
	
						
					
							22.11.2018
Speaker: Prof. Jude Fitzgibbon
Barts Cancer Center, London, UK 
Title: Will new genetic data help cure Follicular Lymphoma?
Location: Room 2609/10 (Medical Building)
Time: 17:00 - 18:00
Host: Prof. Reiner Siebert
 
							
					
			
	
						
					
							30.10.2018
Speaker: Prof. Thomas Kietzmann
University of Oulu, Finnland 
Title: The hypoxia response: Old features and new aspects
Location: Room 2609/10 (Medical Building)
Time: 17:00 - 18:00
Host: Dr. Daniel Mertens and Dr. Viola Close
13.09.2018
Speaker: Dr. Maria de las Nieves Peltzer
UCL Cancer Institute, London, UK 
Title: Physiological role of linear ubiquitination: regulation of cell death-driven inflammation beyond TNF
Location: Room 2609/10 (Medical Building)
Time: 17:00 - 18:00
Host: Prof. Dr. Klaus-Michael Debatin
 
							
					
			
	
						
					
							 27.09.18
Speaker:  Dr. Dimitar Efremov
International Center for Genetic Engineering & Biotechnology
Trieste, Italy
Title:  B cell receptor and associated pathways in CLL: implications for biology and treatment
Location: Room 2622 (Medical Building)
Time: 17:00 - 18:00
Host:  Prof. Hassan Jumaa
 
							
					
			
	
						
					
							13.09.2018
Speaker:
PD Dr. rer. nat. Tanja Hartmann
Internal Medicine I amd Comprehensive Cancer Center Freiburg
Title: 
Creating adhesive spots in leukemia via CD44-mediated non-conformational VLA-4 activation
Location: Multimedia Room 2.059, N27 (Experimental Research Buidling)
Time: 16:00 - 17:00
Host: PD Dr. rer. nat. Daniel Mertens
 
							
					
			
	
						
					
							10.09.2018
SFB 1074 one-day Retreat at Klingenstein Hotel in Blaustein, Ulm
21.06.2018
Speaker:
Dr. Joan Montero Boronat
Institute for Bioengineering of Catalonia
Title: 
Personalizing cancer treatment using cell-based functional assays
Location: SR 2609/10
Time: 16:00 - 17:00
Host: PD Dr. Lüder Meyer and Dr. Felix Seyfried
06.06.2018
Speaker:
Prof. Tsvee Lapidot
The Weizmann Institute of Science, Tel Aviv, Israel
Title: 
Metabolic regulation of blood and bone forming stem cells: The role of ROS, mitochondria transfer, Nitric Oxide and Melatonin
Location: Multimedia Room 2.059, N27 (Experimental Research Building)
Time: 17:00 - 18:00
Host: Prof. Hartmut Geiger
 
							
					
			
	
						
					
							04.05.2018
Speaker:
Dr. Marco Herling
Universitätsklinik Köln, Germany
Title: 
Are novel molecular insights already changing therapeutic approaches in T-PLL?
Location: Seminar Room 2622 (Medical Building)
Time: 10:00 - 11:00
Host: Prof. Reiner Siebert and Dr. Rabea Wagener
 
							
					
			
	
						
					
							26.04.2018
Speaker:
Dr. Chris Halsey
Institute of Cancer Sciences - University of Glasgow, Scottland, UK
Title: 
The continuing challenge of central nervous system infiltration in Acute Lymphoblastic Leukemina
Location: Seminar Room 2609/10 (Medical Building)
Time: 16:00 - 17:00
Host: PD Dr. Lüder Meyer
 
							
					
			
	
						
					
							05.03.2018
Joint Seminar talk with CEMMA
Speaker:
Prof. Constanze Bonifer
Institute for Cancer Genomic Sciences, University of Birmingham, UK
Title: 
Subtype-specific regulatory network rewiring in acute myeloid leukemia
Location: Seminar Room 2609/10 (Medical Building)
Time: 16:00 - 17:00
Host: Prof. Hartmut Geiger
 
							
					
			
	
						
					
							22.02.2018
Speaker:
Dr. Stefano Casola
IFOM, The FIRC Institute of Molecular Oncology Foundation, Milan, Italy
Title: 
Targeting cancer cell fitness: lessons from MYC-driven lymphomas
Location: Seminar Room 2609/10 (Medical Building)
Time: 16:00 - 17:00
Host: Elias Hobeika
 
							
					
			
	
						
					
							25. & 26.01.2018
SFB 1074 Retreat at Hotel liebes Rot-Flüh in Tannheimer Tal, Austria
01.02.2018
Speaker:
PD Dr. Ilske Oschlies
Christian-Albrechts-Universität zu Kiel
Universitätsklinikum Schleswig-Holstein, Campus Kiel
Title:
Clinical, hostomorphological and molecular characteristics of primary cutaneous B-cell lymphomas
Location: Multimedia Room 2.059, N27 (Experimental Cancer Center)
Time: 16:00 - 17:00
Hosts: Prof. Reiner Siebert and Dr. Rabea Wagener
18.01.2018
Speaker:
Dr. Tobias Berg
Universitätsklinikum Frankfurt
Title:
LSD1 - promising target in AML 
Location: Seminar Room 2609/10
Time: 16:00 - 17:00
Host: Dr. Florian Kuchenbauer
<link file:336466 download internen link im aktuellen>Announcement
16.11.2017
Speakers:
Prof. Arndt Borkhardt and Prof. Julia Hauer
Universitätsklinikum Düsseldorf
Titles:
Germline predisposition in childhood cancer - first results of a monocenter study in Düsseldorf (Prof. Borkhardt)
Can infection trigger childhood acute lymphoblastic leukemia (Prof. Hauer)
Location: Seminar Room 2609/10
Time: 16:00 - 17:30
Host: Prof. Reiner Siebert
<link file:318360 download internen link im aktuellen>Announcement
 
							
					
			
	
						
					
							09.10.2017
Speaker:   Prof. Brian Wilhelm
Université de Montreal
Title:  Systematic studies of human models of leukemia: establishing a pipeline for novel targeted therapeutics
Location: Seminar Room 2609/10
Time: 16:00 - 17:00
Host:  Dr. Arefeh Rouhi
 
							
					
			
	
						
					
							04.05.2017
Mini-Symposium:
Location: Hörsaal Chirurgie
Time: 16:30 - 18:00
Speakers:  
Dr. Oliver Weigert
Klinikum der Universität München
Title:  Clinical implications of gene mutation in follicular lymphoma
Host:  Prof. Stephan Stilgenbauer
Dr. José A. Cancelas Perez
University of Cincinnati College of Medicine
Title:  The signaling axis atypical protein kinase C λ/ι/Satb2 mediates leukemic transformation of B-cell precursors
Host: Hartmut Geiger
Announcement  
20.04.2017
Speaker:   Dr. Sandrine Sander
dkfz Heidelberg
Title:  PI3K signaling in B cell lymphoma pathogenesis
Location:  Room 2609/10
Time:  16:00 - 17:00
Host:  Prof. Lars Bullinger
30.03.2017
Speaker:   Dr. med. Cyrus Khandanpour
Universitätsklinikum Essen
Title: Function of Gfi1 in leukemia
Time:  16:00 - 17:00
Location:  Room 2609/10
Host: Prof. Konstanze Döhner
 
							
					
			
	
						
					
							08.03.2017
Speaker:   Prof. Galina Selivanova
Karolinska Institutet Stockholm
Time:  17:00 - 18:00
Location:  Room 2622
Title:  Pharmacological reactivation of p53 to treat cancer
Host: PD Dr. Lüder Meyer
16.02.2017
Speaker:   Dr. Michael Heuser
Medizinische Hochschule Hannover
Time:  16:00 - 17:00
Location:  Room 2609/10
Title:  Pathogenesis of IDH mutations in AML 
Host: Prof. Lars Bullinger 
30.01.2017
Speaker:  Ben Ebert
Harvard Medical Center
Boston, Massachussets, USA
Title:  Pathogenesis of IDH mutations in AML
Time: 16:30 - 17:30
Location: Hörsaal Chirurgie
Host: Hartmut Döhner and Jan Krönke
 
							
					
			
	
						
					
							26.01.2017
Speaker:  Massimo Degano
Ospedale San Raffaele
Milano, Italy
Title:  Molecular analysis of homotypic B cell receptor interactions in chronic lymphocytic leukemia
Time: 16:30 - 17:30
Location: Room 2609/10
Host:  Hassan Jumaa
15.12.2016
Speaker:  Atan Gross
Weizmann Institute
Rehovot, Israel
Title:  The ATM-BID-MTCH2 pathway regulates haematopoietic stem cell fate by controlling mitochondria metabolism
Time: 16:30 - 17:30
Location: Room 2609/10
Host:  Hans-Jörg Fehling
 
							
					
			
	
						
					
							24.11.2016
Speaker:  Florian Bassermann
Klinikum rechts der Isar, TUM
Munich, Germany
Title:  The B cell receptor: key molecule in CLL pathogenesis and therapy
Time:  16:00 - 17:00
Location:  Experimental Research Building, Room 2.059
Host:  Jan Krönke
18.10.2016 (Tuesday)
 
Speaker:   Jan Burger
MD Anderson Cancer Center
Houston, TX, USA
Title:
The B cell receptor: key molecule in CLL pathogenesis and therapy
Time:
16:00 - 17:00
Location:
Seminar Room 2609/10, Medical Building
Host:
Lüder H. Meyer and Peter Gierschik
Announcement 
 
							
					
			
	
						
					
							29.09.2016
Speaker:   Frank Rosenbauer
Westfälische Wilhelms-Universität Münster
Title:
Epigenetic control of lineage decisions in hematopoiesis and leukemia
Time:
16:00 - 17:00
Location:
Experimental Research Building N27, Room 2.059
Host:
Lars Bullinger
Announcement
 
							
					
			
	
						
					
							27.07.2016 (Wednesday)
Speaker: Christian Reinhardt
 Uniklinik Köln
 Köln, Germany
 Title:  Mapping synergistic drug interactions onto the cancer genome
 Time:  16:00 - 17:00
 Location:  SR 2609/10 (Medical Building - N23)
 Host:  Stephan Stilgenbauer
 Announcement
 
							
					
			
	
						
					
							21.07.2016 (Thursday)
 
 Speaker:  Philipp Jost
 Klinikum rechts der Isar, Technische Universität München
 Munich, Germany
 Title:  Inflammatory cell death in AML: unexpected implications for leukemia survival and blast cell differentiation
 Time:  16:00 - 17:00
 Location:  SR 2609/10 (Medical Building - N23)
 Host:  Hartmut Döhner
 Announcement
 
							
					
			
	
						
					
							02.06.2016
Speaker:   Christian Montag
 Ulm University
 Ulm, Germany
 Title:  Molecular genetics in psychological sciences: personality and beyond
 Time:  17:00 - 18:00
 Location:  SR 2609/10 (Medical Building - N23)
 Host:  Lars Bullinger
 Announcement
 
							
					
			
	
						
					
							 
						 
						 
						 
						 
						 
						 
						 
						 
						 
						 
						 
						 
						 
						 
						 
						 
						 
						 
						 
						 
						 
						 
						 
						 
						 
						 
						 
						 
						 
						 
						 
						 
						 
						 
						 
						 
						 
						 
						 
						 
						 
						 
						 
						 
						 
						 
						 
						 
						 
						 
						 
						 
						 
						 
						