Fluorescent Nanodiamonds (FND) offer new potential in imaging and spectroscopy. They are biocompatible and therefore can be used inside of live cells. Frederike investigates, how FNDs can be functionalized to enable specific binding and develop novel sensors.
The combination of plasmonic nanostructures and soft materials offers new possibilities in the field of sensor technology. Peter uses different lithography methods to develop gold nanodisk arrays integrated into Polydimethylsiloxane (PDMS) substrates. These are investigated for their use as force sensors for several applications in biophysics.
For the detailed analysis of the cellular mechano-response to stretch, Fabian develops a cell stretching device combined with an atomic force microscope.
To determine the detailed structural properties of the focal adhesion protein complexes, Lydia uses Metal Induced Energy Transfer with Fluorescence Lifetime Imaging Microscopy to get nanometer resolution. She is further investigating the complexities of the actin cytoskeleton using these techniques, demonstrating their effectiveness in clarifying molecular structures.
The goal of her project is to combine an artificial lung-on-a-chip with a strain sensor.
Dorothee is our MTA and cultivates our cells in the S1 lab.