Knöll group

Mammalian genomes comprise thousands of genes. But which are the right genes to be switched on or off and which gene regulators actually direct the appropriate timing and spatial resolution of gene expression? We study how such selective genome usage by transcription Factors ensures development of such sophisticated and delicate organs as the brain. Particular emphasis is given to those processes during initial brain wiring relying on neuronal motility including nerve Fiber growth and pathfinding. How are dynamic cytoskeletal alterations underlying motility processes sensed by nuclear gene regulators? We study the transcription factor SRF (serum response factor) to understand cytoskeletal-nuclear communication in neurons. The neuronal wiring machinery operating during brain development might get reactivated upon neuronal injury. We try to apply insights obtained during physiological neuronal circuit assembly to understand mechanisms and provide repair strategies for brain rehabilitation in e.g. axonal regeneration. Did we spark your interest? Highly motivated students at any level are welcome to join us on this endeavour. Feel free to contact Bernd Knoll for available positions. 


New video presenting work of the laboratory associated with collaborative research center 1149 on trauma research


Members

Phone +49-731-500-Email
Arbeitsgruppenleiter
Prof. Dr. Bernd Knöll33 839bernd.knoell(at)uni-ulm.de
Postdoktorand
Dr. Sofia Anastasiadou33846sofia.anastasiadou(at)uni-ulm.de
Doktoranden
Philip Förstner31 117philip.foerstner(at)uni-ulm.de
Lisa Hipp31 117lisa.hipp(at)uni-ulm.de
Pascal Lösing23 269pascal.loesing(at)uni-ulm.de
Corinna Schilling31 117corinna.schilling(at)uni-ulm.de
Renate Wanner31 117renate.wanner(at)uni-ulm.de
Medizindoktoranden
Stephanie Haverkamp31 117stephanie.haverkamp(at)uni-ulm.de
Gabi Mroz31 117gabi.mroz(at)uni-ulm.de
Sophie Liebenehm31 117sophie.liebenehm(at)uni-ulm.de
Theresa Schatz31 117
Bachelorstudenten
Techn. Mitarbeiter
Daniela Sinske33 821daniela.sinske(at)uni-ulm.de
wiss. Hilfskräfte
Lisa Kwapichlisa.kwapich(at)uni-ulm.de

Contact

  • Fon: +49 (0)731/500-23271
    Fax: +49 (0)731/500-22892
  • Office

  • Postal Address:
  • University of Ulm
  • Institute of Physiological Chemistry
    Albert-Einstein-Allee 11
  • D-89081 Ulm

  • Suppliers Address:
  • University of Ulm
  • Institute of Physiological Chemistry
  • N27
    Meyerhofstrasse
    D-89081 Ulm

 

Alumni

Henning Beck

Manuel Gey

Franziska Gehringer

Enikö Kokai

Martina Messner

Christopher Meyer zu Reckendorf

Eva Schwarz

Ulrike Sebert