Full Publication List


U. Baschant, L. Frappart, U. Rauchhaus, L. Bruns, H. M. Reichardt, T. Kamradt, R. Brauer and J. P. Tuckermann, "Glucocorticoid therapy of antigen-induced arthritis depends on the dimerized glucocorticoid receptor in T cells", Proc. Natl. Acad. Sci. U.S.A., vol. 108, no. 48, pp. 19317-19322, 2011.
T. Röszer, M. P. Menendez-Gutierrez, M. I. Lefterova, D. Alameda, V. Nunez, M. A. Lazar, T. Fischer and M. Ricote, "Autoimmune kidney disease and impaired engulfment of apoptotic cells in mice with macrophage peroxisome proliferator-activated receptor gamma or retinoid X receptor alpha deficiency", J. Immunol., vol. 186, no. 1, pp. 621-631, 2011.
S. Kushnir, I. C. Cirstea, L. Basiliya, N. Lupilova, R. Breitling and K. Alexandrov, "Artificial linear episome-based protein expression system for protozoon Leishmania tarentolae", Mol. Biochem. Parasitol., vol. 176, no. 2, pp. 69-79, 2011.
M. Rauner, C. Goettsch, N. Stein, S. Thiele, M. Bornhaeuser, K. De Bosscher, G. Haegeman, J. P. Tuckermann and L. C. Hofbauer, "Dissociation of osteogenic and immunological effects by the selective glucocorticoid receptor agonist, compound A, in human bone marrow stromal cells", Endocrinology, vol. 152, no. 1, pp. 103-112, 2011.
M. Asada, A. Rauch, H. Shimizu, H. Maruyama, S. Miyaki, M. Shibamori, H. Kawasome, H. Ishiyama, J. P. Tuckermann and H. Asahara, "DNA binding-dependent glucocorticoid receptor activity promotes adipogenesis via Kr'fcppel-like factor 15 gene expression", Lab. Invest., vol. 91, no. 2, pp. 203-215, 2011.
J. Luther, F. Driessler, M. Megges, A. Hess, B. Herbort, V. Mandic, M. M. Zaiss, A. Reichardt, C. Zech, J. P. Tuckermann, C. F. Calkhoven, E. F. Wagner, G. Schett and J. P. David, "Elevated Fra-1 expression causes severe lipodystrophy", J. Cell. Sci., vol. 124, no. Pt 9, pp. 1465-1476, 2011.
L. Gremer, T. Merbitz-Zahradnik, R. Dvorsky, I. C. Cirstea, C. P. Kratz, M. Zenker, A. Wittinghofer and M. R. Ahmadian, "Germline KRAS mutations cause aberrant biochemical and physical properties leading to developmental disorders", Hum. Mutat., vol. 32, no. 1, pp. 33-43, 2011.


Y. Chen, S. Qiao, J. P. Tuckermann, S. Okret and M. Jondal, "Thymus-derived glucocorticoids mediate androgen effects on thymocyte homeostasis", FASEB J., vol. 24, no. 12, pp. 5043-5051, 2010.
U. Baschant and J. P. Tuckermann, "The role of the glucocorticoid receptor in inflammation and immunity", J. Steroid Biochem. Mol. Biol., vol. 120, no. 2-3, pp. 69-75, 2010.
S. Schmidt, F. Essmann, I. C. Cirstea, F. Kuck, H. C. Thakur, M. Singh, A. Kletke, R. U. Janicke, C. Wiek, H. Hanenberg, M. R. Ahmadian, K. Schulze-Osthoff, B. Nurnberg and R. P. Piekorz, "The centrosome and mitotic spindle apparatus in cancer and senescence", Cell Cycle, vol. 9, no. 22, pp. 4469-4473, 2010.
S. Schmidt, L. Schneider, F. Essmann, I. C. Cirstea, F. Kuck, A. Kletke, R. U. Janicke, C. Wiek, H. Hanenberg, M. R. Ahmadian, K. Schulze-Osthoff, B. Nurnberg and R. P. Piekorz, "The centrosomal protein TAC C3 controls paclitaxel sensitivity by modulating a premature senescence program", Oncogene, vol. 29, no. 46, pp. 6184-6192, 2010.
T. J. Lopes, T. Luganskaja, M. Vujić Spasić, M. W. Hentze, M. U. Muckenthaler, K. Schumann and J. G. Reich, "Systems analysis of iron metabolism: the network of iron pools and fluxes", BMC Syst Biol, vol. 4, pp. 112, 2010.
R. Frijters, W. Fleuren, E. J. Toonen, J. P. Tuckermann, H. M. Reichardt, H. van der Maaden, A. van Elsas, M. J. van Lierop, W. Dokter, J. de Vlieg and W. Alkema, "Prednisolone-induced differential gene expression in mouse liver carrying wild type or a dimerization-defective glucocorticoid receptor", BMC Genomics, vol. 11, pp. 359, 2010.
E. M. Gazdag, I. C. Cirstea, R. Breitling, J. Lukes, W. Blankenfeldt and K. Alexandrov, "Purification and crystallization of human Cu Zn superoxide dismutase recombinantly produced in the protozoan Leishmania tarentolae", Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun., vol. 66, no. Pt 8, pp. 871-877, 2010.
L. Fuentes, T. Röszer and M. Ricote, "Inflammatory mediators and insulin resistance in obesity: role of nuclear receptor signaling in macrophages", Mediators Inflamm., vol. 2010, pp. 219583, 2010.
T. Röszer and M. Ricote, "PPARs in the Renal Regulation of Systemic Blood Pressure", PPAR Res, vol. 2010, pp. 698730, 2010.
A. Rauch, S. Seitz, U. Baschant, A. F. Schilling, A. Illing, B. Stride, M. Kirilov, V. Mandic, A. Takacz, R. Schmidt-Ullrich, S. Ostermay, T. Schinke, R. Spanbroek, M. M. Zaiss, P. E. Angel, U. H. Lerner, J. P. David, H. M. Reichardt, M. Amling, G. Schutz and J. P. Tuckermann, "Glucocorticoids suppress bone formation by attenuating osteoblast differentiation via the monomeric glucocorticoid receptor", Cell Metab., vol. 11, no. 6, pp. 517-531, 2010.
I. C. Cirstea, K. Kutsche, R. Dvorsky, L. Gremer, C. Carta, D. Horn, A. E. Roberts, F. Lepri, T. Merbitz-Zahradnik, R. König, C. P. Kratz, F. Pantaleoni, M. L. Dentici, V. A. Joshi, R. S. Kucherlapati, L. Mazzanti, S. Mundlos, M. A. Patton, M. C. Silengo, C. Rossi, G. Zampino, C. Digilio, L. Stuppia, E. Seemanova, L. A. Pennacchio, B. D. Gelb, B. Dallapiccola, A. Wittinghofer, M. R. Ahmadian, M. Tartaglia and M. Zenker, "A restricted spectrum of NRAS mutations causes Noonan syndrome", Nat. Genet., vol. 42, no. 1, pp. 27-29, 2010.
S. Shalapour, K. Deiser, O. Sercan, J. P. Tuckermann, K. Minnich, G. Willimsky, T. Blankenstein, G. J. Hammerling, B. Arnold and T. Schuler, "Commensal microflora and interferon-gamma promote steady-state interleukin-7 production in vivo", Eur. J. Immunol., vol. 40, no. 9, pp. 2391-2400, 2010.
J. P. Tuckermann, W. Bourguet and S. Mandrup, "Meeting report: nuclear receptors: transcription factors and drug targets connecting basic research with translational medicine", Mol. Endocrinol., vol. 24, no. 7, pp. 1311-1321, 2010.
T. Röszer, E. Kiss-Toth, D. Rozsa, T. Jozsa, A. J. Szentmiklosi and G. Banfalvi, "Hypothermia translocates nitric oxide synthase from cytosol to membrane in snail neurons", Cell Tissue Res., vol. 342, no. 2, pp. 191-203, 2010.
X. Prieur, T. Röszer and M. Ricote, "Lipotoxicity in macrophages: evidence from diseases associated with the metabolic syndrome", Biochim. Biophys. Acta, vol. 1801, no. 3, pp. 327-337, 2010.
C. Maes, S. Goossens, S. Bartunkova, B. Drogat, L. Coenegrachts, I. Stockmans, K. Moermans, O. Nyabi, K. Haigh, M. Naessens, L. Haenebalcke, J. P. Tuckermann, M. Tjwa, P. Carmeliet, V. Mandic, J. P. David, A. Behrens, A. Nagy, G. Carmeliet and J. J. Haigh, "Increased skeletal VEGF enhances beta-catenin activity and results in excessively ossified bones", EMBO J., vol. 29, no. 2, pp. 424-441, 2010.


E. Chichelnitskiy, A. Vegiopoulos, M. Berriel Diaz, A. Ziegler, A. Kleiman, A. Rauch, J. P. Tuckermann and S. Herzig, "In vivo phosphoenolpyruvate carboxykinase promoter mapping identifies disrupted hormonal synergism as a target of inflammation during sepsis in mice", Hepatology, vol. 50, no. 6, pp. 1963-1971, 2009.
S. Wust, D. Tischner, M. John, J. P. Tuckermann, C. Menzfeld, U. K. Hanisch, J. van den Brandt, F. Luhder and H. M. Reichardt, "Therapeutic and adverse effects of a non-steroidal glucocorticoid receptor ligand in a mouse model of multiple sclerosis", PLoS ONE, vol. 4, no. 12, pp. e8202, 2009.