O. Goldbeck, D.N. Desef, K.V. Ovchinnikov, F. Perez-Garcia, J. Christmann, P. Sinner, P. Crauwels, D. Weixler, P. Cao, J. Becker, M. Kohlstedt, J. Kager, B.J. Eikmanns, G.M. Seibold, C. Herwig, C. Wittmann, N.S. Bar, D.B. Diep, C.U. Riedel. Establishing recombinant production of pediocin PA-1 in Corynebacterium glutamicum. Metabolic Engineering. 2021 Sep 4:S1096-7176(21)00141-5. doi: 10.1016/j.ymben.2021.09.002. Online ahead of print. pubmed

C.K. Desiderato, S. Sachsenmaier, K.V. Ovchinnikov, J. Stohr, S. Jacksch, D.N. Desef, P. Crauwels, M. Egert, D.B. Diep, O. Goldbeck, C.U. Riedel. Identification of Potential Probiotics Producing Bacteriocins Active against Listeria monocytogenes by a Combination of Screening Tools. International Journal of Molecular Sciences. 2021 Aug 10;22(16):8615. doi: 10.3390/ijms22168615. pubmed

D. Weixler, O. Goldbeck, G.M. Seibold, B.J. Eikmanns, C.U. Riedel. Towards improved resistance of Corynebacterium glutamicum against nisin. bioRxiv. 2021.08.09.454123. doi: 

B. Nikparvar, A. Subires, M. Capellas, M. Hernandez-Herrero, P. Crauwels, C.U. Riedel, N. Bar. A Diffusion Model to Quantify Membrane Repair Process in Listeria monocytogenes Exposed to High Pressure Processing Based on Fluorescence Microscopy Data. Frontiers in Microbiology. 2021 May 13;12:598739. doi: 10.3389/fmicb.2021.598739. pubmed

I.C. Duru, F.I. Bucur, M. Andreevskaya, A. Ylinen, P. Crauwels, L. Grigore-Gurgu, B. Nikparvar, T.M. Rode, P. Laine, L. Paulin, T. Løvdal, C.U. Riedel, N. Bar, D. Borda, A.I. Nicolau, P. Auvinen. The complete genome sequence of Listeria monocytogenes strain S2542 and expression of selected genes under high-pressure processing. BMC Res Notes. 2021 Apr 15;14(1):137. doi: 10.1186/s13104-021-05555-2. pubmed

B. Nikparvar, M. Andreevskaya, I.C. Duru, F.I. Bucur, L. Grigore-Gurgu, D. Borda, A.I. Nicolau, C.U. Riedel, P. Auvinen, N. Bar. Analysis of temporal gene regulation of Listeria monocytogenes revealed distinct regulatory response modes after exposure to high pressure processing. BMC Genomics. 2021 Apr 14;22(1):266. doi: 10.1186/s12864-021-07461-0. pubmed

O. Goldbeck, D. Weixler, B.J. Eikmanns, C.U. Riedel. In Silico Prediction and Analysis of Unusual Lantibiotic Resistance Operons in the Genus Corynebacterium. Microorganisms. 2021 Mar 19;9(3):646. doi: 10.3390/microorganisms9030646. pubmed

V. Palmieri, J.-F. Ebel, N. Ngo Thi Phuong, R. Klopfleisch, V. Pham Vu, A. Adamczyk, J. Zöller, C. Riedel, J. Buer, P. Krebs, W. Hansen, E. Pastille, A.M. Westendorf. Interleukin-33 signaling exacerbates experimental infectious colitis by enhancing gut permeability and inhibiting protective Th17 immunity. Mucosal Immunology. 2021. 2021 Jul;14(4):923-936. doi: 10.1038/s41385-021-00386-7. pubmed

I.C. Duru, F.I. Bucur, M. Andreevskaya, B. Nikparvar, A. Ylinen, L. Grigore-Gurgu, T.M. Rode, P. Crauwels, P. Laine, L. Paulin, T. Løvdal, C.U. Riedel, N. Bar, D. Borda, A.I. Nicolau, P. Auvinen. High-pressure processing-induced transcriptome response during recovery of Listeria monocytogenes. BMC Genomics. 2021 Feb 12;22(1):117. doi: 10.1186/s12864-021-07407-6. pubmed


I.C. Duru, M. Andreevskaya, P. Laine, T.M. Rode, A. Ylinen, T. Løvdal, N. Bar, P. Crauwels, C.U. Riedel, I.F. Bucur, A. Nicolau, P. Auvinen. Genomic characterization of the most barotolerant Listeria monocytogenes RO15 strain compared to reference strains used to evaluate food high pressure processing. BMC Genomics. 2020 Jul 2;21(1):455. doi: 10.1186/s12864-020-06819-0. pubmed


E. Herdoiza Padilla, P. Crauwels, T. Bergner, N. Wiederspohn, S. Förstner, R. Rinas, A. Ruf, M. Kleemann, R. Handrick, J. Tuckermann, K. Otte, P. Walther, C.U. Riedel.  mir-124-5p Regulates Phagocytosis of Human Macrophages by Targeting the Actin Cytoskeleton via the ARP2/3 Complex. Front Immunol. 2019 Oct 4;10:2210. doi: 10.3389/fimmu.2019.02210 pubmed

C. Conzelmann, M. Zou, R. Groß, M. Harms, A. Röcker, C.U. Riedel, J. Münch, J.A. Müller. Storage-Dependent Generation of Potent Anti-ZIKV Activity in Human Breast Milk. Viruses. 2019 Jun 28;11(7). pii: E591. doi: 10.3390/v11070591. pubmed

M. Zetzmann, F.I. Bucur, P. Crauwels, D. Borda, A.I. Nicolau, L. Grigore-Gurgu, G.M. Seibold, C.U. Riedel. Characterization of the biofilm phenotype of a Listeria monocytogenes mutant deficient in agr peptide sensing. Microbiology Open. 2019 Mar 6:e826. doi: 10.1002/mbo3.826. pubmed



P. Crauwels, L. Schäfer, D. Weixler, N.S. Bar, D.B. Diep, C.U. Riedel*, G.M. Seibold. Intracellular pHluorin as sensor for easy assessment of bacteriocin-induced membrane-damage in Listeria monocytogenes. Front Microbiol. 2018 Dec 11. doi: 10.3389/fmicb.2018.03038.  pubmed

F.I. Bucur, L. Grigore-Gurgu, P. Crauwels, C.U. Riedel, A.I. Nicolau. Resistance of Listeria monocytogenes to Stress Conditions Encountered in Food and Food Processing Environments. Front Microbiol. 2018. Nov 13. doi: 10.3389/fmicb.2018.02700. pubmed

M. Kleemann, H.  Schneider, K. Unger, J. Bereuther, S. Fischer, P. Sander, M.E. Schneider, P. Fischer-Posovszky, C.U. Riedel, R. Handrick, K. Otte. Induction of apoptosis in ovarian cancer cells by miR-493-3p directly targeting AKT2, STK38L, HMGA2, ETS1 and E2F5. Cell Mol Life Sci. 2018 Nov 3. doi: 10.1007/s00018-018-2958-x. [Epub ahead of print] pubmed

E. Herrmann, W. Young, V. Reichert-Grimm, S. Weis, C.U. Riedel, D. Rosendale, H. Stoklosinski, M. Hunt, M. Egert. In Vivo Assessment of Resistant Starch Degradation by the Caecal Microbiota of Mice Using RNA-Based Stable Isotope Probing-A Proof-of-Principle Study. Nutrients. 2018 Feb 6;10(2). pii: E179. doi: 10.3390/nu10020179. pubmed


E. Herrmann, W. Young, D. Rosendale, R. Conrad, C.U. Riedel*, M. Egert. Determination of Resistant Starch Assimilating Bacteria in Fecal Samples of Mice by in vitro RNA-Based Stable Isotope Probing. Front Microbiol. 2017. Jul 24;8:1331. doi: 10.3389/fmicb.2017.01331. pubmed        

M. Egert, R. Simmering, C.U. Riedel. The association of the skin microbiota with health, immunity and disease. Clin Pharmacol Ther. 2017 Jul;102(1):62-69. doi: 10.1002/cpt.698. pubmed

E. Herrmann, W. Young, D. Rosendale, V. Reichert-Grimm, C.U. Riedel, R. Conrad, M. Egert. RNA-Based Stable Isotope Probing Suggests Allobaculum spp. as Particularly Active Glucose Assimilators in a Complex Murine Microbiota Cultured In Vitro. Biomed Res Int. 2017;2017:1829685. doi: 10.1155/2017/1829685. pubmed

E. Herrmann, P. Koch, C.U. Riedel, W. Young, M. Egert. Effect of rotor type on the separation of isotope-labeled and unlabeled Escherichia coli RNA by isopycnic density ultracentrifugation. Can J Microbiol. 2017 Jan;63(1):83-87. pubmed


M. Kleemann, J. Bereuther, S. Fischer, K. Marquart, S. Hänle, K. Unger, V. Jendrossek, C.U. Riedel, R. Handrick, K. Otte. Investigation on tissue specific effects of pro-apoptotic micro RNAs revealed miR-147b as a potential biomarker in ovarian cancer prognosis. Oncotarget. 2016 Nov 4. doi: 10.18632/oncotarget.13095. [Epub ahead of print] pubmed

V. Rossini, K. Radulovic, C.U. Riedel, Niess JH. Development of an Antigen-driven Colitis Model to Study Presentation of Antigens by Antigen Presenting Cells to T Cells. J Vis Exp. 2016 Sep 18;(115). pubmed

C. Westermann, M. Gleinser, S.C. Corr, C.U. Riedel. A Critical Evaluation of Bifidobacterial Adhesion to the Host Tissue. Front. Microbiol. 2016;7:1220. pubmed

M. Zetzmann, A. Sánchez-Kopper, M.S. Waidmann, B. Blombach, C.U. Riedel. Identification of the agr Peptide of Listeria monocytogenes. Front Microbiol. 2016 Jun 22;7:989. pubmed

X. Wei,  S. Wang,  X. Zhao,  X. Wang,  H. Li,  W. Li,  J Lu, D. Zhurina,  B. Li,  C.U. Riedel*,  Y. Sun, J. Yuan. Proteomic profiling of Bifidobacterium bifidum S17 cultivated under in vitro conditions. Front. Microbiol. 2016 Feb 12;7:97. * corresponding author pubmed


M. Zetzmann, M. Okshevsky, J. Endres, A. Sedlag, N. Caccia, M. Auchter, M.S. Waidmann, M. Desvaux, R.L. Meyer, C.U. Riedel. DNase-Sensitive and -Resistant Modes of Biofilm Formation by Listeria monocytogenes. Front. Microbiol. 2015 Dec 22;6:1428. pubmed

A. Osswald, Z. Sun, V. Grimm, G. Ampem, K. Riegel, A.M. Westendorf, W. Sommergruber, K. Otte, P. Dürre, C.U. Riedel. Three-dimensional tumor spheroids for in vitro analysis of bacteria as gene delivery vectors in tumor therapy. Microb Cell Fact. 2015 Dec 12;14(1):199. pubmed

V. Grimm, K. Radulovic, C.U. Riedel. Colonization of C57BL/6 Mice by a Potential Probiotic Bifidobacterium bifidum Strain under Germ-Free and Specific Pathogen-Free Conditions and during Experimental Colitis. PLoS One. 2015 Oct 6;10(10):e0139935. pubmed

V. Seiffart, J. Zoeller, R. Klopfleisch, M. Wadwa, W. Hansen, J. Buer, C. Riedel, A.M. Westendorf. IL10-Deficiency in CD4⁺ T Cells Exacerbates the IFNγ and IL17 Response During Bacteria Induced Colitis. Cell Physiol Biochem. 2015;36(4):1259-73. pubmed

A. Osswald, C. Westermann, Z. Sun, C.U. Riedel. A phytase-based reporter system for identification of functional secretion signals in bifidobacteria. PLoS One. 2015 Jun 18;10(6):e0128802. pubmed

Z. Sun, V. Grimm, C.U. Riedel. AI-2 to the rescue against antibiotic-induced intestinal dysbiosis? Trends Microbiol. 2015 Jun;23(6):327-8. pubmed


Z. Sun, C. Westermann, J. Yuan, C.U. Riedel. Experimental determination and characterization of the gap promoter of Bifidobacterium bifidum S17. Bioengineered. 2014 Nov 2;5(6):371-7. pubmed

V. Grimm, C. Westermann, C.U. Riedel. Bifidobacteria-host interactions--an update on colonisation factors. Biomed Res Int. 2014;2014:960826. doi: 10.1155/2014/960826. Epub 2014 Sep 11. pubmed

Z. Jaglic, M. Desvaux, A. Weiss, L.L. Nesse, R.L. Meyer, K. Demnerova, H. Schmidt, E. Giaouris, A. Sipailiene, P. Teixeira, M. Kačániová, C.U. Riedel, Knøchel S. Surface adhesins and exopolymers of selected foodborne pathogens. Microbiology. 2014 Dec;160(Pt 12):2561-82. pubmed

X. Wei, X. Yan, X. Chen, Z. Yang, H. Li, D. Zou, X. He, S. Wang, Q. Cui, W. Liu, D. Zhurina, X. Wang, X. Zhao, L. Huang, M. Zeng, Q. Ye, C.U. Riedel, J. Yuan. Proteomic analysis of the interaction of Bifidobacterium longum NCC2705 with the intestine cells Caco-2 and identification of plasminogen receptors. J Proteomics. 2014 Aug 28;108:89-98. pubmed

V. Grimm, M. Gleinser, C. Neu, D. Zhurina, C.U. Riedel. Expression of fluorescent proteins in bifidobacteria for analysis of host-microbe interaction. Appl Environ Microbiol. 2014 May;80(9):2842-50. pubmed

F. Bottacini, M. O Connell Motherway, J. Kuczynski, K.J. O Connell, F. Serafini, S. Duranti, C. Milani, F. Turroni, G. Lugli, A. Zomer, D. Zhurina, C. Riedel, M. Ventura, D. van Sinderen. Comparative genomics of the Bifidobacterium breve taxon. BMC Genomics. 2014 Mar 1;15(1):170. pubmed

A. Rahman, M. Gleinser, M.-C. Lanhers, C.U. Riedel, B. Foligné, M. Hanse, F.T. Yen, A Klouj, M.I. Afzal, A. Back, C. Mangavel, C. Cailliez-Grimal, A.-M. Revol-Junelles, F. Borges. Adaptation of the lactic acid bacterium Carnobacterium maltaromaticum LMA 28 to the mammalian gastrointestinal tract: From survival in mice to interaction with human cells. Int Dairy J. 2014 Jan;34(1):93-99.

Z. Sun, X. He, V.F. Brancaccio, J. Yuan, C.U. Riedel. Bifidobacteria Exhibit LuxS-Dependent Autoinducer 2 Activity and Biofilm Formation. PLoS ONE. 2014 Feb 5;9(2):e88260. pubmed

Other selected publications

V. Grimm, M. Gleinser, C. Neu, D. Zhurina, C.U. Riedel. Expression of fluorescent proteins in bifidobacteria for analysis of host-microbe interaction. Appl Environ Microbiol. 2014 May;80(9):2842-50.

V. Rossini, D. Zhurina, K. Radulovic, C. Manta, P. Walther, C.U. Riedel, J.H. Niess. CX3CR1+ cells facilitate the activation of CD4 T cells in the colonic lamina propria during antigen-driven colitis. Mucosal Immunol. 2014 May;7(3):533-48.

C. Neu, A. Sedlag, C. Bayer, S. Förster,P.  Crauwels, J.H. Niess, G. van Zandbergen, G. Frascaroli, C.U. Riedel. CD14-Dependent Monocyte Isolation Enhances Phagocytosis of Listeria monocytogenes by Proinflammatory, GM-CSF-Derived Macrophages. PLoS ONE. 2013 Jun 11;8(6):e66898.

C. Manta, E. Heupel, K. Radulovic, V. Rossini, N. Garbi, C.U. Riedel, J.H. Niess. CX3CR1+ macrophages support IL-22 production by innate lymphoid cells during infection with Citrobacter rodentium. Mucosal Immunol. 2013 Jan;6(1):177-88.

Z. Sun, A. Baur, D. Zhurina, J. Yuan, C.U. Riedel. Accessing the inaccessible: molecular tools for bifidobacteria. Appl Environ Microbiol. 2012 Aug;78(15):5035-42.

M. Gleinser, V. Grimm, D. Zhurina, J. Yuan, C.U. Riedel. Improved adhesive properties of recombinant bifidobacteria expressing the Bifidobacterium bifidum-specific lipoprotein BopA. Microb Cell Fact. 2012 Jun 13;11:80.

J. Preising, D. Philippe, M. Gleinser, H. Wei, S. Blum, B. J. Eikmanns, J.-H. Niess and C.U. Riedel. Selection of bifidobacteria for amelioration of murine colitis based on adhesion and anti-inflammatory capacity in vitro. Appl Environ Microbiol. 2010 May;76(9):3048-51.

C.U. Riedel, I.R. Monk, P.G. Casey, M.S. Waidmann, C.G.M. Gahan, and C. Hill. AgrD-dependent quorum sensing affects biofilm formation, invasion, virulence and global gene expression profiles in Listeria monocytogenes. Mol Microbiol. 2009 Mar;71(5):1177-89.

C.U. Riedel, P. Casey. H. Mulcahy, F. O’Gara, C.G.M. Gahan, and C. Hill. Construction of p16Slux, a novel vector for improved bioluminescent-labelling of Gram-negative bacteria. Appl Environ Microbiol. 2007 Nov;73(21):7092-5.

V. Grimm, M. Gleinser, C. Neu, D. Zhurina, C.U. Riedel. Expression of fluorescent proteins in bifidobacteria for analysis of host-microbe interaction. Appl Environ Microbiol. 2014 May;80(9):2842-50.

C.U. Riedel, I.R. Monk, P. Casey, D. Morrissey, G.C. O’Sullivan, M. Tangney, C. Hill and C.G.M. Gahan. An improved luciferase tagging system for Listeria monocytogenes allows real-time monitoring in vivo and in vitro. Appl Environ Microbiol. 2007 May;73(9):3091-4.

C. Riedel, D. Rittmann, P. Dangel, B. Möckel, S. Petersen, H. Sahm, and B.J. Eikmanns. Characterisation of the phosphoenolpyruvate-carboxykinase gene from Corynebacterium glutamicum and significance of the enzyme for growth and amino acid production. J Mol Microbiol Biotechnol. 2001 Oct;3(4):573-83.

S. Petersen, C. Mack, A. A. de Graaf, C. Riedel, B.J. Eikmanns, and H. Sahm. Anaplerotic substrate cycling in Corynebacterium glutamicum: metabolic consequences of phosphoenolpyruvate carboxykinase activity and inference to anaplerotic regulation in vivo. Metab Eng. 2001 Oct;3(4):344-61.