Institute of Protein Biochemistry

In 2012, the institute was established under the Director Prof. Dr. Marcus Fändrich. Its research as well as its teaching duties are at the interface between biology, chemistry, physics and medicine with the main focus being on protein biochemistry.

Major techniques used at our institute are the recombinant expression and purification of proteins, the biophysical characterization of protein conformations, electron and fluorescence microscopy as well as cell biology.



New publication in Nature Communications. Title: “Physical basis of amyloid fibril polymorphism” Close W, Neumann M, Schmidt A, Hora M, Annamalai K, Schmidt M, Reif B, Schmidt V, Grigorieff N, Fändrich M. Nature Comm. 9, 699 (2018)



The 2nd Ulm Meeting "Biophysics of Amyloid Formation" with a keynote lecture from Ron Wetzel and 100 registered participants from twelve different countries and four continents was sucessfully held at Ulm University.



New publication in Proc. Natl. Acad. Sci. U.S.A.. Title: “Serum amyloid A forms stable oligomers that disrupt vesicles at lysosomal pH and contribute to the pathogenesis of reactive amyloidosis” Jayaraman S, Gantz, DL, Haupt C, Gursky O.  Proc. Natl. Acad. Sci. U.S.A. 114, E6507-E6515 (2017)



New publication in EMBO Reports. Title: “Cellular mechanism of fibril formation from serum amyloid A1 protein” Claus S, Meinhardt K, Aumüller T, Puscalau-Girtu I, Linder J, Haupt C, Walther P, Syrovets T, Simmet T, Fändrich M.  EMBO Rep. 18, 1352-1366 (2017)


Prof. Dr. Marcus Fändrich
Tel: +49-(0)731/50 32750
Fax: +49-(0)731/50 32759
Helmholtzstraße 8/1
Room number 1.55


Carolin Göhring
Tel: +49-(0)731/50 32751
Fax: +49-(0)731/50 32759
Helmholtzstraße 8/1
Room number 1.54


Ulm University
Institute of Protein Biochemistry
Helmholtzstraße 8/1
89081 Ulm


Photo shows the building "Zentrum für Biomediziniksche Forschung" where the Institute is located

Our institute is located within the Zentrum für Biomedizinische Forschung Helmholtzstraße 8/1

Location Google Maps

Useful links

Homepage of Ulm University
Homepage of the Faculty of Natural Sciences
Homepage of the Department of Biology