Referent: Dinesh Deelchand, Ph.D. (Center for Magnetic Resonance Research, University of Minnesota)
Abstract: Subject motion remains a major concern during magnetic resonance spectroscopy (MRS) acquisitions, especially in children, patients with movement disorders, or the elderly, due to typically longer scan times required to achieve sufficient signal-to-noise ratio. Motion during MRS scans often degrades spectral quality, resulting in insufficient water suppression, broader spectral linewidth, reduced SNR, and/or lipid contamination. Even when spectral quality is not visibly degraded, MR spectra may still be recorded from a different brain region than the region of interest (this is especially a concern with very small anatomical targets, such as hypothalamus) and, therefore, provide inaccurate metabolite concentrations. In this talk, I will give a brief summary of prospective motion correction techniques currently available in MRI/MRS. I will also demonstrate and validate real-time motion and shim corrections in the human brain using MRS.