Research Interests

  • Survival and event history, in particular Multistate Models
  • Bootstrap procedures
  • Data processing and management
  • Statistical methodology in randomized clinical trials as well as in epidemiology (e.g., register-based health services research)

Lectures & Courses

Summer Term 19

Winter Term 15/16:

Summer Term 15:

Winter Term 2014/15:




  • Wayan Philipps, Anne-Katrin Fietz, Tobias Bluhmki, Reinhard Meister, Christof Schaefer, Stephanie Padberg: Pregnancy outcome after 1st trimester exposure to fosfomycin for the treatment of urinary tract infection: an observational cohort study. Infection 2019 (early view) . doi 10.1007/s15010-019-01342-1

  • Tobias Bluhmki, Hein Putter, Arthur Allignol, Jan Beyersmann: Bootstrapping complex time-to-event data without individual patient data, with a view towards time-dependent exposures. Statistics in Medicine 2019 (early view). doi 10.1002/sim.8177

  • Tobias Bluhmki , Anne-Katrin Fietz, Regina Stegherr, Evelin Beck , Stephanie
    Padberg, Jan Beyersmann, Christof Schaefer, Reinhard Meister: Multistate methodology improves risks assessment under time-varying exposure – An illustration with a case study in obstetrics. Pharmacoepidemiology and Drug Safety 2019, 28(5): 616-624. doi 0.1002/pds.4710

  • Tobias Bluhmki*, Dennis Dobler*, Jan Beyersmann, Markus Pauly: The Wild Bootstrap for Multivariate Nelson-Aalen Estimators. Lifetime Data Analysis 2019, 25(1): 97-127. doi 10.1007/s10985-018-9423-x


  • Tobias Bluhmki, Arthur Allignol, Stephane Ruckly, Jean-Francois Timsit, Martin Wolkewitz, Jan Beyersmann:  Estimation of adjusted expected excess length-of-stay associated with ventilation-acquired pneumonia in intensive care: A multistate approach accounting for time-dependent mechanical ventilation. Biometrical Journal 2018, 60(6): 1135-1150. doi 10.1002/bimj.201700242

  • Tobias Bluhmki, Claudia Schmoor, Dennis Dobler, Markus Pauly, Jürgen Finke, Martin Schumacher, Jan Beyersmann:  A Wild Bootstrap Approach for the Aalen-Johansen Estimator. Biometrics 2018, 74(3): 977-985. doi 10.1111/biom.12861

  • Harriet Sommer*, Tobias Bluhmki*, Jan Beyersmann, Martin Schumacher: Assessing non-inferiority in treatment trials regarding severe infectious diseases: An extension to the entire follow-up period using a cure-death multistate model.  Antimicrobial Agents and Chemotherapy 2018, 62(1): e01691-17. doi


  • Tobias Bluhmki, Raphael S Peter, Kilian Rapp, Hans-Helmut König, Clemens Becker, Ivonne Lindlbauer, Dietrich Rothenbacher, Jan Beyersmann, Gisela Büchele: Understanding mortality of femoral fractures following low-impact trauma in persons with and without care need.  Journal of the American Medical Directors Association 2017, 18(3): 221-226. doi 10.1016/j.jamda.2016.08.022

  • Tobias Bluhmki, Peter Bramlage, Michael Volk, Matthias Kaltheuner, Thomas Danne, Wolfgang Rathmann, Jan Beyersmann. Time-to-event-Methodology improved Statistical Evaluation in Register-based Health Services Research. Journal of Clinical Epidemiology 2017, 82: 103-111. doi 0.1016/j.jclinepi.2016.11.001

  • Peter Bramlage, Tobias Bluhmki, Holger Fleischmann,  Matthias Kaltheuner, Jan Beyersmann, Reinhard W Holl, Thomas Danne.  Determinants of weight control in patients on basal insulin treatment - an analysis of the DIVE registry.  BMJ Open Diabetes & Care 2017, 4:e000301. doi 10.1136/bmjdrc-2016-000301


  • Peter Bramlage, Tobias Bluhmki, Wolfgang Rathmann, Matthias Kaltheuner, Jan Beyersmann, Thomas Danne: Identifying patients with Type 2 diabetes in which basal supported oral therapy may not be the optimal treatment strategy. Diabetes Research and Clinical Practice 2016, 116: 127–135. doi 10.1016/j.diabres.2016.03.015


  • Thomas Danne, Tobias Bluhmki, Jochen Seufert, Matthias Kaltheuner, Wolfgang Rathmann, Jan Beyersmann, Peter Bramlage: Treatment intensification using long-acting insulin - predictors of future basal insulin supported oral therapy in the DIVE registry. BMC Endocrine Disorders 2015, 15:54. doi 10.1186/s12902-015-0051-0

*equal contribution


Brief CV

  • Since February 2019: Postdoctoral Reasearcher
  • February 2019: Graduation Dr. rer. nat., Biostatistics, awarded by the Faculty of Mathematics and Economics, Ulm University. Title of Dissertation: Statistical Evaluation of Non-Standard Time-to-Event Outcomes in Biomedical Research.
  • April - June 2018: Temporal Internship at Novartis Pharma AG, Basel (Unit: Statistical Methodology)
  • Since Aug. 2014: Research Assistant and Doctoral Student at the Institute of Statistics, University of Ulm
  • Oct. 2012 - June 2014: Studies of Mathematical Biometry (M. Sc.), University of Ulm.
    Title of the Master's-Thesis: Wild Bootstrapping Nelson-Aalen Estimates with Application in Health Services Research (at the Institute of Statistics (Supervisor Prof. Dr. Jan Beyersmann) in cooperation with the Institute of Epidemiology and Medical Biometry, Supervisor Dr. Gisela Büchele ). Winner of the Bernd-Streitberg-Preis (IBS-GR) 2015.
  • Oct. 2009 - Sept. 2012: Studies of Mathematical Biometry (B.Sc.), University of Ulm.
    Title of the Bachelor's Thesis: Within-Subject Variability in Cross-Over Bioequivalence Trials: Assumptions vs. Observations (at the Institute of Epidemiology and Medical Biometry  (Supervisor Prof. Dr. Rainer Muche) in cooperation with the Boehringer Ingelheim Pharma GmBH & Co. KG, Biberach a.d. Riss), presented at the KSFE 2013, Ulm (summary can be found here)


Ulm University
Institute of Statistics
Helmholtzstr. 20 (Room E.45)
89081 Ulm


Phone: (+49) 731/ 50-33104
E-Mail: tobias.bluhmki(at)

Office Hours:

At any time: please make an appointment via e-mail or come spontaneously into my office!