Dr. Merle Stein

Research interest

Bone modeling/remodeling

Osteopetrosis

Osteoimmunology

Metabolism

                             

Academic and Scientific education

 

09/2017 – current, Universität Ulm, Ulm M.D.: Staatsexamen Humanmedizin

04/2012 – 07/2016 Friedrich-Alexander-Universität, Erlangen PhD: Immunology

09/2009 – 12/2011, Friedrich-Schiller-Universität, Jena Master of Science: Microbiology

09/2005 – 07/2008, University of Warwick, Coventry, GB Bachelor of Science: Microbiology/Virology

 

3 selected publications

1. Stein M, Barnea-Zohar M, Shalev M, Arman E, Brenner O, Winograd-Katz S, Gerstung J, Thalji F, Kanaan M, Elinav H, Stepensky P, Geiger B, Tuckermann J, Elson A. Massive osteopetrosis caused by non-functional osteoclasts in R51Q SNX10 mutant mice. Bone. 2020 Jul;136:115360. doi: 10.1016/j.bone.2020.115360. Epub 2020 Apr 8. PMID: 32278070.

2. Ubieta K, Garcia M, Grötsch B, Uebe S, Weber GF, Stein M, Ekici A, Schett G, Mielenz D, Bozec A. Fra-2 regulates B cell development by enhancing IRF4 and Foxo1 transcription. J Exp Med. 2017 Jul 3;214(7):2059-2071. doi: 10.1084/jem.20160514. Epub 2017 May 31. PMID: 28566276; PMCID: PMC5502419.

3. Stein M, Dütting S, Mougiakakos D, Bösl M, Fritsch K, Reimer D, Urbanczyk S, Steinmetz T, Schuh W, Bozec A, Winkler TH, Jäck HM, Mielenz D. A defined metabolic state in pre B cells governs B-cell development and is counterbalanced by Swiprosin-2/EFhd1. Cell Death Differ. 2017 Jul;24(7):1239-1252. doi: 10.1038/cdd.2017.52. Epub 2017 May 19. PMID: 28524857; PMCID: PMC5520169.