Research project NF1 modifying genes
Information for patients
Institute for Human Genetics, University of Ulm, Working group of PD Dr. Dieter Kaufmann
Lab PD Dr.
Modifying genes and NF1
Symptoms of NF1 show a high variability between NF1 patients. For example, on the one hand the number of dermal neurofibromas increases with age, but on the other hand there are NF1 patients of the same age with drastically different number of dermal neurofibromas.
Patients with spinal Neurofibromatosis have neurofibromas distributed along the spinal chord but rarely have dermal neurofibromas.The effects of modifying genes are thought to be a cause for this variability.
The hypothesis is that the NF1 gene determines if a person has a NF1 but another gene determines how many neurofibromas this person will develop. Our research project, funded by the DFG, aims at identifying such a modifying gene.
We need your help
Our project can only succeed if certain NF1 patients will help us.
How can you help?
You can help us, if you belong to one of the following three groups of patients:
If you want to help us
please write to PD Dr. Dieter Kaufmann, Department of Human Genetics, University of Ulm, Albert Einstein Allee 11, 89070 Ulm, Germany
or write an e-mail: firstname.lastname@example.org
or call us: +49-731-50065450