The Rhesus Site RHD Gene Rh Blood Group Antigen ISBT004
Explore the Intricacies of the Most Complex Blood Group Gene Locus
Details transfusion medicine, immunohematology, and genetic and molecular research in the field. 
RHD Mutation Database

The RHD Mutation Database

Rhesus Immunization Registry
Rhesus Immunization Registry
Theoretical 3D model
Theoretical model of the antigen D
on the red blood cell surface (Feb 1998)
Rhesus locus at human chromosome 1
Structure of the RH gene locus and model for RHD gene deletion event (2000)
Duplication event: RHCE is ancestral & RHD duplicated (2002)

Hairpin formation
instrumental for gene conversion events (2001)

Previous model of the Rhesus genes´ locus (1998)
RHD positive haplotypes
in antigen D negative
Europeans: Abstract
 
Request a number for a new weak D allele


Request a weak D type number:

Details suggested requirements
and procedure for deposition
of a newly found weak D allele.

Examples




BloodGen consortium link

The Future of Blood Grouping:
Mass Genotyping for Blood Groups
Symposium website
  24 September 2004   Mannheim

4th International Workshop: Rh flow cytometry section
4th International Workshop on
Monoclonal Antibodies against
Human Red Blood Cells and
Related Antigens

Rh flow cytometry
19 and 20 July 2001   Paris


 

Online Publications
RHD allele distribution in Africans of Mali Abstract (2003) Full text
The DAU allele cluster of the RHD gene Abstract (2002) Full text
RHD positive haplotypes in antigen D negative Europeans Abstract (2001) Full text
Original paper: Frequency and typing strategy for Rhesus D   Summary (1995) Full text

Online Reviews

Review: The Genetics of the Rhesus Blood Group System (2007) in English (auf deutsch)
Review: the molecular basis of the Rh blood group phenotypes (2004)
Molecular biology of partial D and weak D: Implications for blood bank practice (2002)
Editorial: Genotyping and Phenotyping Full text (1999)
Review on Rhesus molecular genetics   Summary (1998) Full text

Online Theses
List of Thesis work in the field of Rhesus
Other Rhesus Related Resources
Rhesus blood group 111680 - Online-Mendelian Inheritance in Man (OMIM - National Institutes of Health)
Introduction to the Rh blood group system ( SCARF - Hahnemann University, Philadelphia)
Blood Group Antigen Mutation Database ( RH - Albert Einstein College, New York)
Rh Blood Group System Module ( Rh Module - University of Alberta)
The Human Gene Mutation Database Cardiff ( HGMD - University of Wales)
Red Blood Cell related methods ( RBC methods )
German Guidelines for antigen D typing 1996/2000 ( English translation )

Other Blood Group Related Resources
Aquaporin = water channel in cell membranes Animations   Nobel e-Museum (2003)
Blood group antigens as auto-antigens, Budapest presentation, animated slide show 6.3 MB (2004)
Scianna antigens including Rd are expressed by ERMAP Abstract OMIM SCARF  
Slide show (2003)
Links in German
Genetik des Rhesus-Blutgruppensystems (Übersichtsarbeit). Deutsches Ärzteblatt 2007 Dt. Ärzteblatt Heft 10, 9.3.2007
Molekularbiologie von partial D und weak D: Bedeutung für die Arbeit in der Blutzentrale Übersicht  MTA Dialog 3(2002)662
Rhesus Immunisierungsregister der DGTI
Molekulargenetische Blutgruppendiagnostik Übersicht (2001)
Genotypisierung und Phänotypisierung Editorial (1999)
Die molekulare Basis der RH-Haplotypen mit schwacher Expression des Antigens D Habilitationsschrift Universität Ulm 1999
Schematische Darstellung des Antigens D (1998)
Rhesus D-Bestimmung beim Transfusionsempfänger Technische Übersicht MTA 13(1998)83
Bedeutung nicht-funktionaler Allele für die Genotypisierung Habilitationsschrift Universität Ulm 1997

Lippert HD, Flegel WA
Kommentar zum Transfusionsgesetz (TFG) und den Hämotherapie-Richtlinien.
2002. XXXIX, 521 S. Geb.

ISBN 3-540-41816-4
Read representatitive chapters online, go to the "Dokumente für klinische Anwender" online, go to the online link list of this book or purchase it online.

WA Flegel   All publications Our Research & Development activities
Homepage Abteilung Blutgruppenserologie und Immunhämatologie, Institut für Klinische Transfusionsmedizin und Immungenetik Ulm (IKT Ulm), Germany
Sponsored by the DRK-Blutspendedienst Baden-Württemberg - Hessen gGmbH, Mannheim