Publications

2022

Ming DK, Tuan NM, Hernandez B, Sangkaew S, Vuong NL, Chanh HQ, Chau NVV, Simmons CP, Wills B, Georgiou P, Holmes AH, Yacoub S,  VC. The Diagnosis of Dengue in Patients Presenting With Acute Febrile Illness Using Supervised Machine Learning and Impact of Seasonality. Frontiers in Digital Health. 2022; 4849641.      [DOI] 

2021

Schwab P, Karlen W. A Deep Learning Approach to Diagnosing Multiple Sclerosis from Smartphone Data. IEEE Journal of Biomedical and Health Informatics. 2021; 25(4):1284--1291.      [DOI]      [File] 
Zhang J, Karlen W. A novel quality indicator for displaying and comparing the missingness of the PPG derived respiratory rate. In: Society for Technology in Anaesthesia Annual Meeting 2021 (STA 2021). 2021. p. 67.      [DOI] 
Snipes S, Huber R, Karlen W. A response to Basner et al. (2021): “Response speed measurements on the psychomotor vigilance task: how precise is precise enough?". Sleep. 2021; 44(7):      [DOI]      [File] 
Clark I, Stucky B, Azza Y, Schwab P, Müller S, Weibel D, Button D, Karlen W, Seifritz E, Kleim B, Landolt H. Diurnal variations in multi-sensor wearable-derived sleep characteristics in morning- and evening-type shift workers under naturalistic conditions. Chronobiology International. 2021; 38(12):1702-1713.      [DOI]      [File] 
Ferretti A, Ienca M, Sheehan M, Blasimme A, Dove ES, Farsides B, Friesen P, Kahn J, Karlen W, Kleist P, Liao SM, Nebeker C, Samuel G, Shabani M, Rivas Velarde M, Vayena E. Ethics review of big data research: What should stay and what should be reformed?. BMC Medical Ethics. 2021; 22(1):51.      [DOI]      [File] 
Meinke A, Peters R, Knols R, Karlen W, Swanenburg J. Exergaming Using Postural Feedback From Wearable Sensors and Exercise Therapy to Improve Postural Balance in People With Nonspecific Low Back Pain: Protocol for a Factorial Pilot Randomized Controlled Trial. JMIR Research Protocols. 2021; 10(8):e26982.      [DOI]      [File] 
Coleman J, Ginsburg AS, Macharia WM, Ochieng R, Zhou G, Dunsmuir D, Karlen W, Ansermino JM. Identification of thresholds for accuracy comparisons of heart rate and respiratory rate in neonates. Gates Open Research. 2021; 593.      [DOI]      [File] 
Fröhlich S, Helbling M, Fucentese SF, Karlen W, Frey WO, Spörri J. Injury risks among elite competitive alpine skiers are underestimated if not registered prospectively, over the entire season and regardless of whether requiring medical attention. Knee Surgery, Sports Traumatology, Arthroscopy. 2021; 29(5):1635--1643.      [DOI]      [File] 
Scebba G, Da Poian G, Karlen W. Multispectral Video Fusion for Non-Contact Monitoring of Respiratory Rate and Apnea. IEEE Transactions on Biomedical Engineering. 2021; 68(1):350--9.      [DOI]      [File] 
Zhang J, Mihai C, Tüshaus L, Scebba G, Distler O, Karlen W. Wound Image Quality From a Mobile Health Tool for Home-Based Chronic Wound Management With Real-Time Quality Feedback: Randomized Feasibility Study. JMIR mHealth and uHealth. 2021; 9(7):e26149.      [DOI]      [File] 

2020

Hartinger SM, Nuño N, Hattendorf J, Verastegui H, Karlen W, Ortiz M, Mäusezahl D. A factorial cluster-randomised controlled trial combining home-environmental and early child development interventions to improve child health and development: rationale, trial design and baseline findings. BMC medical research methodology. 2020; 20(1):73.      [DOI]      [File] 
Leach S, Chung K, Tüshaus L, Huber R, Karlen W. A Protocol for Comparing Dry and Wet EEG Electrodes During Sleep. Frontiers in Neuroscience. 2020; 14586.      [DOI]      [File] 
Muroi C, Meier S, De Luca V, Mack DJ, Strässle C, Schwab P, Karlen W, Keller E. Automated False Alarm Reduction in a Real-Life Intensive Care Setting Using Motion Detection. Neurocritical Care. 2020; 32(2):419--426.      [DOI]      [File] 
Schneider N, Ferster M, Lustenberger C, Schlegel J, Karlen W, Huber R, Maric A, Baumann CR. Can auditory slow wave stimulation during chronic sleep restriction intensify subjective recovery?. Journal of Sleep Research. 2020; 29225.
Sousouri G, Krugliakova E, Skorucak J, Leach S, Ferster M, Poian GD, Karlen W, Huber R. Changes in slow-wave traveling after phase targeted auditory stimulation of the up and down phase of sleep slow waves. Journal of Sleep Research. 2020; 29234.
Zhang J, Scebba G, Karlen W. Covariance intersection to improve the robustness of the photoplethysmogram derived respiratory rate. In: 42nd Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC). Montreal, CA: IEEE; 2020. p. 5939--42.      [DOI]      [File] 
Geissmann L, Käch M, Laube S, Zhang J, Karlen W. Data Integrity for the Internet of Medical Things - Real Time Quality Monitoring for Data Streams from Wearable Sensors. In: Swiss Medtech Day 2020. Berne: 2020.      [DOI] 
Hüser M, Kündig A, Karlen W, De Luca V, Jaggi M. Forecasting intracranial hypertension using multi-scale waveform metrios. Physiological Measurement. 2020; 41(1):014001.      [DOI]      [File] 
Maeder T, Whitford J, Feinaigle P, Karlen W, Seifritz E, Pace-Schott EF, Kleim B. Investigating Pre-Sleep Processes and How They Influence Sleep: A Diary and Actigraphy Study. Sleep. 2020; 43(Supplement{\_}1):A211--A211.      [DOI]      [File] 
Schwab P, Linhardt L, Bauer S, Buhmann JM, Karlen W. Learning Counterfactual Representations for Estimating Individual Dose-Response Curves. Proceedings of the AAAI Conference on Artificial Intelligence. 2020; 34(04):5612--5619.      [DOI]      [File] 
Krugliakova E, Skorucak J, Sousouri G, Leach S, Ferster L, Poian GD, Karlen W, Huber R. Mapping changes in delta band power following auditory stimulation targeting slow wave up-and down-phases: a source-localization study. Journal of Sleep Research. 2020; 29
Ding X, Yan BP, Karlen W, Zhang Y, Tsang HK. Pulse transit time based respiratory rate estimation with singular spectrum analysis. Medical & Biological Engineering & Computing. 2020; 58(2):257--266.      [DOI]      [File] 
Behar JA, Liu C, Kotzen K, Tsutsui K, Corino VDA, Singh J, Pimentel MAF, Warrick P, Zaunseder S, Andreotti F, Sebag D, Kopanitsa G, McSharry PE, Karlen W, Karmakar C, Clifford GD. Remote health diagnosis and monitoring in the time of COVID-19. Physiological Measurement. 2020; 41(10):      [DOI]      [File] 
Clark I, Stucky B, Azza Y, Müller S, Karlen W, Seifritz E, Kleim B. Shift work-related circadian disruption on diurnal rest-activity and sleep patterns in morning-and evening-type first responders under naturalistic conditions. Journal of Sleep Research. 2020; 29147.
Albrecht J, Altermatt S, Brotschi B, Baumann C, Ferster M, Karlen W, Huber R. Sleep after concussion: long-term monitoring in children and adolescents in a home-setting. Journal of Sleep Research. 2020; 29355.
Stucky B, Clark I, Azza Y, Müller S, Karlen W, Achermann P, Kleim B. Validation of a wearable heart rate and sleep tracker compared with polysomnography in police and rescue workers under natural conditions. Journal of Sleep Research. 2020; 2978.
Dutt AG, Verling M, Karlen W. Wearable bioimpedance for continuous and context-aware clinical monitoring. In: 42nd Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC). Montreal, CA: IEEE; 2020. p. 3985--8.      [DOI]      [File] 

2019

Brogli L, Karlen W. A Review of Deep Learning for Automatic Sleep Stage Scoring. In: International Conference on Advanced Sleep Modulation Technologies. Monte Verita, Ascona, Switzerland: 2019.
Zhou G, Karlen W, Brant R, Wiens M, Kissoon N, Ansermino JM. A transformation of oxygen saturation (the saturation virtual shunt) to improve clinical prediction model calibration and interpretation. Pediatric Research. 2019; 3--10.      [DOI]      [File] 
Ansermino JM, Dunsmuir D, Karlen W, Gan H, Dumont GA. Are respiratory rate counters really so bad? Throwing the baby out with the bath water. In: EClinicalMedicine. 2019. p. 14.      [DOI]      [File] 
Karlen W. Automated point-of-care processing and interpretation of pulse oximetry for global health applications. In: 41st International Engineering in Medicine and Biology Conference: Biomedical Engineering Ranging From Wellness To Intensive Care (EMBC 2019). 2019. p. WeC04.4.      [DOI] 
Ferster ML, Lustenberger C, Karlen W. Configurable Mobile System for Autonomous High-Quality Sleep Monitoring and Closed-Loop Acoustic Stimulation. IEEE Sensors Letters. 2019; 3(5):1--4.      [DOI]      [File] 
Schwab P, Karlen W. CXPlain: Causal Explanations for Model Interpretation under Uncertainty}. In: Annual Conference on Neural Information Processing Systems 2019, NeurIPS 2019. Vancouver, CA: 2019. p. accepted.     [File] 
Azza Y, Clark I, Müller S, Karlen W, Landolt H, Kleim B. Der Einfluss von Schlaf auf intrusive emotionale Erinnerungen bei Einsatzkräften. In: 11. Workshopkongress für Klinische Psychologie und Psychotherapie. 2019.
Lustenberger C, Ferster ML, Huwiler S, Karlen W. Effective long-term slow wave modulation in elderly using in-home , closed-loop auditory stimulation. In: International Conference on Advanced Sleep Modulation Technologies. Monte Verita, Ascona, Switzerland: 2019.
Schwab P, Miladinovic D, Karlen W. Granger-Causal Attentive Mixtures of Experts: Learning Important Features with Neural Networks. Proceedings of the AAAI Conference on Artificial Intelligence. 2019; 334846--53.      [DOI]      [File] 
Ferster ML, Lustenberger C, Karlen W. Hitting the phase : How filtering parameters affect the EEG slow wave phase analysis. In: International Conference on Advanced Sleep Modulation Technologies. Monte Verita, Ascona, Switzerland: 2019.
Azza Y, Grueschow M, Karlen W, Seifritz E, Kleim B. How stress affects sleep and mental health: Nocturnal heartrate increases during prolonged stress and interacts with childhood trauma exposure to predict anxiety. Sleep. 2019;      [DOI]      [File] 
Pham NM, Rusch S, Temiz Y, Beck H, Karlen W, Delamarche E. Immuno-gold silver staining assays on capillary-driven microfluidics for detection of malaria antigens. Biomedical microdevices. 2019; 21(1):24.      [DOI]      [File] 

Forschungsschwerpunkte