Recent publications affiliated with the DZKJ Site Ulm

Albers DPJ, Novikova S, Vieyto-Nuñez J, Almeida-Hernández Y, Pastorio C, Klassen F, Weiss D, von Maltitz P, Jaikishan J, Datta M, Jumaa H, Jebaraj BMC, Stilgenbauer S, Kumar M, Maity PC, Buske C, Stifel U, Zinngrebe J, Fischer-Posovszky P, Chevigné A, Kirchhoff F, Sanchez-Garcia E, Münch J and Harms M. GPR15LG binds CXCR4 and synergistically modulates CXCL12-induced cell signaling and migration. Cell Commun Signal. 2025 May; 23(1):234.

Alshammari WS, Duncan EM, Vita L, Kenawy M, Dibnah B, Wabitsch M, Gould GW and Hudson BD. Inverse agonism of the FFA4 free fatty acid receptor controls both adipogenesis and mature adipocyte function. Cell Signal. 2025 July; 131:111714.

Argente J, Farooqi IS, Chowen JA, Kühnen P, López M, Morselli E, Gan H-W, Spoudeas HA, Wabitsch M and Tena-Sempere M. Hypothalamic obesity: from basic mechanisms to clinical perspectives. Lancet Diabetes Endocrinol. 2025 January; 13(1):57-68.

Bundschu K, Aleksandrova-Yankulovska S, Denzer C, Dornbrach T, Eberhart S, Glisic L, Barata AG, Gündel H, Hönig K, Janni W, Khinda K, Rafensteiner L, Siebert R, Steger F, Stilgenbauer S, Wabitsch M, Wiesmüller L, Wilhelm M, Wojak B and Hancke K. Future perspectives of fertility protection. J Reprod Immunol. 2025 March; 168:104455.

Clemens V, Wernecke D, Fegert JM, Genuneit J, Rothenbacher D and Braig S. Maternal child maltreatment and trajectories of offspring behavioural and emotional difficulties from age 4 to 7 years - results from a prospective birth cohort study. Eur Child Adolesc Psychiatry. 2025 March; 34(3):1039-1050.

Glaser S, Wagener R, Kretzmer H, López C, Baptista MJ, Bens S, Bernhart S, Bhatia K, Borkhardt A, Elgaafary S, Hoffmann S, Hübschmann D, Hummel M, Klapper W, Kolarova J, Kreuz M, Lazzi S, Löffler M, Navarro JT, Neequaye J, Onyango N, Onyuma T, Ott G, Radlwimmer B, Rohde M, Rosenwald A, Rosolowski M, Schlesner M, Szczepanowski M, Tapia G, Wößmann W, Küppers R, Trümper L, Leoncini L, Lichter P, Del Val C, Ammerpohl O, Burkhardt B, Mbulaiteye SM, Siebert R, Consortium IM and Project MMML. Subtyping Burkitt Lymphoma by DNA Methylation. Genes Chromosomes Cancer. 2025 April; 64(4):e70042.

Hecker D, Song X, Baumgarten N, Diagel A, Katsaouni N, Li L, Li S, Maji RK, Behjati Ardakani F, Ma L, Tews D, Wabitsch M, Björkegren JLM, Schunkert H, Chen Z and Schulz MH. Cell type-specific epigenetic regulatory circuitry of coronary artery disease loci. bioRxiv. 2025 February [Epub ahead of print].

Heymsfield SB, Clément K, Dubern B, Goldstone AP, Haqq AM, Kühnen P, Richards J, Roth CL, Akker ELTvd, Wabitsch M and Yanovski JA. Defining Hyperphagia for Improved Diagnosis and Management of MC4R Pathway-Associated Disease: A Roundtable Summary. Curr Obes Rep. 2025 January; 14(1):13.

Lang J, Bergner T, Zinngrebe J, Lepelley A, Vill K, Leiz S, Wlaschek M, Wagner M, Scharffetter-Kochanek K, Fischer-Posovszky P, Read C, Crow YJ, Hirschenberger M and Sparrer KMJ. Distinct pathogenic mutations in ARF1 allow dissection of its dual role in cGAS-STING signalling. EMBO Rep. 2025 May; 26(9):2232-2261.

Martin L, Maric D, Idriss S, Delamare M, Le Roy A, Maaziz N, Caillaud A, Si-Tayeb K, Robriquet F, Lenglet M, Erceau L, Bellanné-Chantelot C, Plo I, Aral B, Garrec C, Airaud F, Gianfermi C, Antunes V, Keppner A, Vincent SM, Desfontaine A, Modé N, Laporte F, Gaignerie A, Chariau C, Leray I, Rogue C, David L, Redon R, Bézieau S, Mansour-Hendili L, Galactéros F, Maillet T, Pasquet M, Cougoul P, Nloga A-M, Gardin C, Guitton C, Dubruille V, Giacobbi-Milet V, Leblanc T, Kaya Z, Semama D, James C, Carillo S, Ochmann M, Waage A, Mortier E, Maillasson M, Quéméner A, Cario H, Skoda RC, Zermati Y, Hoogewijs D, Marchand A, Girodon F and Gardie B. Identification of Hepatic-like EPO as a Cause of Polycythemia. N Engl J Med. 2025 May; 392(17):1684-1697.

Niedermayer A, Stursberg J, Bergmann AK, Zimmermann M, Cario G, Brüggemann M, Köhler R, Steinbach D, Reimann C, Seyfried F, Meyer LH and Debatin K-M. Remission induction in refractory, drug resistant pediatric PICALM::MLLT10+ B-cell acute lymphoblastic leukemia by venetoclax. Leukemia. 2025 April [Epub ahead of print].

Peng Z, Siziba LP, Brenner H, Wernecke D, Rothenbacher D and Genuneit J. Changes in Childhood Atopic Dermatitis Incidence and Risk Factors Over Time: Results From Two German Birth Cohorts. Clin Exp Allergy. 2025 April [Epub ahead of print].

Peng Z, Siziba LP, Mank M, Stahl B, Gonsalves J, Wernecke D, Rothenbacher D and Genuneit J. Profiles of 71 Human Milk Oligosaccharides and Novel Sub-Clusters of Type I Milk: Results from the Ulm SPATZ Health Study. Nutrients. 2025 January; 17(2).

Schirmer M, Zorn S, von Schnurbein J and Wabitsch M. Innovative Care for Children and Adolescents with Severe and/or Genetic Obesity. Horm Res Paediatr. 2025 March:1-10 [Epub ahead of print].

Schmidt ENC, Evert BO, Pregler BEF, Melhem A, Hsieh M-C, Raspe M, Strobel H, Roos J, Pietsch T, Schuss P, Fischer-Posovszky P, Westhoff M-A, Hölzel M, Herrlinger U, Vatter H, Waha A, Schneider M and Potthoff A-L. Tonabersat enhances temozolomide-mediated cytotoxicity in glioblastoma by disrupting intercellular connectivity through connexin 43 inhibition. Mol Oncol. 2025 March; 19(3):878-898.

Schmidt H, Menrath I, Wiegand S, Reinehr T, Kiess W, Hebebrand J, von Schnurbein J, Holl RW, Holle R, Scherag A, Wabitsch M and Brandt-Heunemann S. Youths with Extreme Obesity: A High-Risk Group for Pain and Mental Health Impairments. Obes Facts. 2025 ; 18(1):21-30.

Vinnai BÁ, Arianti R, Fischer-Posovszky P, Wabitsch M, Fésüs L and Kristóf E. The importance of thiamine availability in the thermogenic competency of human adipocytes. Mol Cell Endocrinol. 2025 April; 599:112483.

Zorn S, de Groot CJ, Brandt-Heunemann S, von Schnurbein J, Abawi O, Bounds R, Ruck L, Guijo B, Martos-Moreno GÁ, Nicaise C, Courbage S, Klehr-Martinelli M, Siebert R, Dubern B, Poitou C, Clément K, Argente J, Kühnen P, Farooqi IS, Wabitsch M and van den Akker E. Early childhood height, weight, and BMI development in children with monogenic obesity: a European multicentre, retrospective, observational study. Lancet Child Adolesc Health. 2025 May; 9(5):297-305.

van den Berg N, Tomczyk S, Kölch M, Schmidt S, Heckmann M and Wabitsch M. Versorgung und Prävention bei Adipositas bei Kindern und Jugendlichen – Ansätze der Community Medicine Adipositas. 2024 June; 18(02):51-55.

Eigemann J, Janda A, Schuetz C, Lee-Kirsch MA, Schulz A, Hoenig M, Furlan I, Jacobsen E-M, Zinngrebe J, Peters S, Drewes C, Siebert R, Rump E-M, Führer M, Lorenz M, Pannicke U, Kölsch U, Debatin K-M, von Bernuth H, Schwarz K and Felgentreff K. Non-Skewed X-inactivation Results in NF-κB Essential Modulator (NEMO) Δ-exon 5-autoinflammatory Syndrome (NEMO-NDAS) in a Female with Incontinentia Pigmenti. J Clin Immunol. 2024 September; 45(1):1.

Fischer-Posovszky P and Zinngrebe J. Brown adipose tissue fights the battle against leukaemia. Nat Rev Endocrinol. 2024 December; 20(12):699-700.

Gärtner J, Berner R, Debatin K-M, Klein C, Körner A, Mall MA, Muntau AC and van den Berg N. Deutsches Zentrum für Kinder- und Jugendgesundheit: Interdisziplinäre Forschung für eine gesunde Zukunft von Kindern und Jugendlichen Monatsschr Kinderheilkd. 2024 June; 172(8):704-710.

Giannopoulou EZ, Brandt S, Zorn S, Denzer C, von Schnurbein J, Fukami M, Kaiser A, Schmidt M and Wabitsch M. Long term effects of aromatase inhibitor treatment in patients with aromatase excess syndrome. Front Endocrinol. 2024 ; 15:1487884.

Yu GZ, Krentz NAJ, Bentley L, Zhao M, Paphiti K, Sun H, Honecker J, Nygård M, Dashti H, Bai Y, Reid M, Thaman S, Wabitsch M, Rajesh V, Yang J, Mattis KK, Abaitua F, Casero R, Hauner H, Knowles JW, Wu JY, Mandrup S, Claussnitzer M, Svensson KJ, Cox RD and Gloyn AL. Loss of RREB1 reduces adipogenesis and improves insulin sensitivity in mouse and human adipocytes. bioRxiv. 2024 July [Epub ahead of print].

Zorn S, Schirmer M, von Schnurbein J, Brandt S, Göpel E, Stein R, Wiegand S, Körner A, Kühnen P and Wabitsch M. Versorgungskonzepte für Kinder und Jugendliche mit extremer und/oder genetischer Adipositas Adipositas. 2024 June; 18(02):71-80.