The ULMTeC Core Facility Genomics of the Faculty of Medicine offers services for all working groups of the hospital, university and external companies/universities for their research. The Genomics Core Facility consists of the former chip facility and the newly established 'Next Generation Sequencing' unit.

The sequencing service includes the entire experimental planning as well as the bioinformatic evaluation and supervision of the projects (Prof. Dr. H. A. Kestler (Institute of Medical Systems Biology) & Dr. K. Holzmann (Genomics Core Facility)).

QuickLinks

Submit a sample DFG funding high-throughput sequencing Cost reduction Bioinformatics 

 

In the field of next-generation sequencing, the Genomics Core Facility initially used an Illumina HiSeq 2000 from 2013 to 2019. This was then replaced by a NextSeq 550, which offered significantly greater flexibility in terms of the size of sequencing projects.

Since July 2025, we are now able to carry out sequencing projects on a NextSeq 1000. This enables a significant reduction in sequencing costs in the range of 25-50% (depending on the project), compared to the NextSeq 550.  This sequencing instrument can also perform various standard analyses directly on the device at no additional cost.

Customers who do not require bioinformatics support can therefore expect to receive their data much faster in future.

Sequencing services:

• Whole Genome Sequencing
• Exome Sequencing
• Panel sequencing
• RNA sequencing (also from minimal amounts of RNA)
• miRNA sequencing (also from plasma, from exosomes)
• ChIP sequencing
• Microbiome sequencing
• Single Cell RNA Seq (Chromium iX)

In the area of Microarrays, a system from Affymetrix is available as well as a microarray spotter to produce custom arrays.

Microarrays Services:

• Expression profile analyses
• miRNA analyses
• SNP/Copy Number analyses
• ChIP on Chip analyses
• Sequencing of mitochondrial DNA
• Support in the establishment of custom arrays