Medical Faculty

Core Unit Mass Spectrometry and Proteomics (CUMP)

Das Symbolbild stellt die Methodik der Core Unit Massenspektrometrie und Proteomics von Proteinidentifizierung über -aufreinigung bis zur Analyse und Quantifizierung dar.

The Core Unit Mass Spectrometry and Proteomics (CUMP) offers state-of-the-art proteomic research to all members of the University Medical Center and Ulm University as well as to external industrial and academic partners.

The services provided by the CUMP include all steps of proteomics based research. From conceptional advice to experimental procedures and practical tipps a detailed guidance is provided by the members of the CUMP. Employing SCX-chromatography and/or SDS-PAGE offer powerfull sample fractionation methods. Different fragmentation methods (CID, HCD, MSA) can be employed during MS analysis. For data analysis tailored software tools are available.

The established methods and technologies allow the tackling of a broad spectrum of biological and medical relevant questions. Whereby complex qualitative as well as quantitative (SILAC, label-free, isobaric tags) analyses can be performed.


The services of the CUMP at glance:

  • Protein/Peptid fractionation (SDS-PAGE, SCX-Chromatography)
  • Proteolytic diegst
  • Peptida enrichment (e.g. TiO2-enrichment of phosphopeptides)
  • Mass spectrometric anlysis
  • Bioinformatical data anlysis (qualitativ and quantitativ)
  • Statistics
Die Orbitrap Velos Pro erlaubt die Identifizierung und Quantifizierung tausender Proteine.

More Information

The following posters demonstrate the current research activities performed at the CUMP.

As part of two research consortia, CUMP is performing extensive method development in fields such as intact protein analysis, PTM enrichment, and endogenous peptide identification. The following posters outline our current efforts in these fields.

Contact

Please direct project initiations or any other communication to:

Dr. Sebastian Wiese
phone: +49 731/500 - 65512
fax: +49 731/500 - 65502

Analysis Requests

Please direct your analysis request to:
med.proteomics(at)uni-ulm.de

Please bring the sample submission with you upon delivery of samples to the CUMP.

Navigation

Peptide Libraries
Posters/Publications
Group

Address

Office: N26/5209 (Fifth Floor, through east wing 4th floor)

Lab: N26/4204 (Fourth Floor, east wing)

Albert-Einstein Allee 11
89081 Ulm