Publications

You find here a complete list of publications authored or coauthered by members of our institute since 1974. By default the entire list is presented.

2018

739.
Fischer, V.; Haffner-Luntzer, M.; Amling, M.; Ignatius, A.
Calcium and vitamin D in bone fracture healing and post-traumatic bone turnover
Eur Cell Mater, 35 :365–385
2018
DOI:10.22203/eCM.v035a25
738.
Schlager, B.; Krump, F.; Boettinger, J.; Niemeyer, F.; Ruf, M.; Kleiner, S.; Beer, M.; Wilke, H.-J.
Characteristic morphological patterns within adolescent idiopathic scoliosis may be explained by mechanical loading
Eur Spine J, 27 (9) :2184–2191
2018
DOI:10.1007/s00586-018-5622-0
737.
Aebi, M.; Maas, C.; Treuheim, T.; Friedrich, H.; Wilke, H. J.
Comparative biomechanical study of a new transpedicular vertebral device and vertebroplasty for the treatment or prevention of vertebral compression fractures
Clin Biomech (Bristol, Avon), 56 :40–45
2018
DOI:10.1016/j.clinbiomech.2018.05.001
736.
Jonas, R.; Demmelmaier, R.; Hacker, S. P.; Wilke, H. J.
Comparison of three-dimensional helical axes of the cervical spine between in vitro and in vivo testing
Spine J, 18 (3) :515–524
2018
DOI:10.1016/j.spinee.2017.10.065
735.
Modinger, Y.; Löffler, B.; Huber-Lang, M.; Ignatius, A.
Complement involvement in bone homeostasis and bone disorders
Semin Immunol, 37 :53–65
2018
DOI:10.1016/j.smim.2018.01.001
734.
Xu, P.; Werner, J.; Milerski, S.; Hamp, C.; Kuzenko, T.; Jahnert, M.; Gottmann, P.; Roy, L.; Warnecke, D.; Abaei, A.; Palmer, A.; Huber-Lang, M.; Dürselen, L.; Rasche, V.; Schurmann, A.; Wabitsch, M.; Knippschild, U.
Diet-induced obesity affects muscle regeneration after murine blunt muscle trauma – a broad spectrum analysis
Front Physiol, 9 :674
2018
DOI:10.3389/fphys.2018.00674
733.
Prystaz, K.; Kaiser, K.; Kovtun, A.; Haffner-Luntzer, M.; Fischer, V.; Rapp, A. E.; Liedert, A.; Strauss, G.; Waetzig, G. H.; Rose-John, S.; Ignatius, A.
Distinct effects of interleukin-6 classic and trans-signaling in bone fracture healing
Am J Pathol, 188 (2) :474–490
2018
DOI:10.1016/j.ajpath.2017.10.011
732.
Hacker, S. P.; Schall, F.; Niemeyer, F.; Wolf, N.; Ignatius, A.; Dürselen, L.
Do Prophylactic Knee Braces Protect the Knee Against Impacts or Tibial Moments? An In Vitro Multisensory Study
Orthop J Sports Med, 6 (11) :2325967118805399
2018
DOI:10.1177/2325967118805399
731.
Haffner-Luntzer, M.; Lackner, I.; Liedert, A.; Fischer, V.; Ignatius, A.
Effects of low-magnitude high-frequency vibration on osteoblasts are dependent on estrogen receptor alpha signaling and cytoskeletal remodeling
Biochem Biophys Res Commun, 503 (4) :2678–2684
2018
DOI:10.1016/j.bbrc.2018.08.023
730.
Haffner-Luntzer, M.; Kovtun, A.; Lackner, I.; Modinger, Y.; Hacker, S.; Liedert, A.; Tuckermann, J.; Ignatius, A.
Estrogen receptor alpha- (ERalpha), but not ERbeta-signaling, is crucially involved in mechanostimulation of bone fracture healing by whole-body vibration
Bone, 110 :11–20
2018
DOI:10.1016/j.bone.2018.01.017
729.
Meyers, N.; Schulke, J.; Ignatius, A.; Claes, L.
Evolution of callus tissue behavior during stable distraction osteogenesis
J Mech Behav Biomed Mater, 85 :12–19
2018
DOI:10.1016/j.jmbbm.2018.05.017
728.
Galbusera, F.; Niemeyer, F.; Seyfried, M.; Bassani, T.; Casaroli, G.; Kienle, A.; Wilke, H.-J.
Exploring the Potential of Generative Adversarial Networks for Synthesizing Radiological Images of the Spine to be Used in In Silico Trials
Front Bioeng Biotechnol, 6 (53)
2018
DOI:10.3389/fbioe.2018.00053
727.
Friedrich, D. T.; Dürselen, L.; Mayer, B.; Hacker, S.; Schall, F.; Hahn, J.; Hoffmann, T. K.; Schuler, P. J.; Greve, J.
Features of haptic and tactile feedback in TORS-a comparison of available surgical systems
J Robot Surg, 12 (1) :103–108
2018
DOI:10.1007/s11701-017-0702-4
726.
Teixeira, G.; Pereira, C.; Ferreira, J. R.; Maia, A.; Gomez-Lazaro, M.; Barbosa, M. A.; Neidlinger-Wilke, C.; Goncalves, R. M.
Immunomodulation of human mesenchymal stem/stromal cells in intervertebral disc degeneration: insights from a proinflammatory/degenerative ex vivo model.
Spine, 43 (12) :E673–E682
2018
DOI:10.1097/BRS.0000000000002494
725.
Dornacher, D.; Lippacher, S.; Nelitz, M.; Reichel, H.; Ignatius, A.; Dürselen, L.; Seitz, A. M.
Impact of five different medial patellofemoral ligament-reconstruction strategies and three different graft pre-tensioning states on the mean patellofemoral contact pressure: a biomechanical study on human cadaver knees
J Exp Orthop, 5 (1) :25
2018
DOI:10.1186/s40634-018-0140-x
724.
Majewski, M.; Heisterbach, P.; Jaquiery, C.; Dürselen, L.; Todorov, A.; Martin, I.; Evans, C. H.; Müller, S. A.
Improved tendon healing using bFGF, BMP-12 and TGFbeta1 in a rat model
Eur Cell Mater, 35 :318–334
2018
DOI:10.22203/eCM.v035a22
723.
Liebsch, C.; Zimmermann, J.; Graf, N.; Schilling, C.; Wilke, H. J.; Kienle, A.
In vitro validation of a novel mechanical model for testing the anchorage capacity of pedicle screws using physiological load application
J Mech Behav Biomed Mater, 77 :578–585
2018
DOI:10.1016/j.jmbbm.2017.10.030
722.
Rapp, A. E.; Hachemi, Y.; Kemmler, J.; Koenen, M.; Tuckermann, J.; Ignatius, A.
Induced global deletion of glucocorticoid receptor impairs fracture healing
FASEB J, 32 (4) :2235–2245
2018
DOI:10.1096/fj.201700459RR
721.
Fischer, V.; Kalbitz, M.; Muller-Graf, F.; Gebhard, F.; Ignatius, A.; Liedert, A.; Haffner-Luntzer, M.
Influence of Menopause on Inflammatory Cytokines during Murine and Human Bone Fracture Healing
Int J Mol Sci, 19 (7) :2070
2018
DOI:10.3390/ijms19072070
720.
Schlager, B.; Niemeyer, F.; Liebsch, C.; Galbusera, F.; Boettinger, J.; Vogele, D.; Wilke, H. J.
Influence of morphology and material properties on the range of motion of the costovertebral joint - a probabilistic finite element analysis
Comput Methods Biomech Biomed Engin, 21 (14) :731–739
2018
DOI:10.1080/10255842.2018.1516762
719.
Schuelke, J.; Meyers, N.; Reitmaier, S.; Klose, S.; Ignatius, A.; Claes, L.
Intramembranous bone formation after callus distraction is augmented by increasing axial compressive strain
PLoS One, 13 (4) :e0195466
2018
DOI:10.1371/journal.pone.0195466
718.
Volkheimer, D.; Galbusera, F.; Liebsch, C.; Schlegel, S.; Rohlmann, F.; Kleiner, S.; Wilke, H. J.
Is intervertebral disc degeneration related to segmental instability? An evaluation with two different grading systems based on clinical imaging
Acta Radiol, 59 (3) :327–335
2018
DOI:10.1177/0284185117715284
717.
Halbgebauer, R.; Schmidt, C. Q.; Karsten, C. M.; Ignatius, A.; Huber-Lang, M.
Janus face of complement-driven neutrophil activation during sepsis
Semin Immunol, 37 :12–30
2018
DOI:10.1016/j.smim.2018.02.004
716.
Haffner-Luntzer, M.; Kovtun, A.; Fischer, V.; Prystaz, K.; Hainzl, A.; Kroeger, C. M.; Krikki, I.; Brinker, T. J.; Ignatius, A.; Gatzka, M.
Loss of p53 compensates osteopenia in murine Mysm1 deficiency
FASEB J, 32 (4) :1957–1968
2018
DOI:10.1096/fj.201700871R
715.
Pietsch, M.; Niemeyer, F.; Simon, U.; Ignatius, A.; Urban, K.
Modelling the fracture-healing process as a moving-interface problem using an interface-capturing approach
Comput Methods Biomech Biomed Engin, 21 (8) :512–520
2018
DOI:10.1080/10255842.2018.1487554
714.
Hachemi, Y.; Rapp, A.; Picke, A. K.; Weidinger, G.; Ignatius, A.; Tuckermann, J.
Molecular Mechanisms of Glucocorticoids on Skeleton and Regeneration after Fracture
J Mol Endocrinol, 61 (1) :R75–R90
2018
DOI:10.1530/JME-18-0024
713.
Foerstner, P.; Rehman, R.; Anastasiadou, S.; Haffner-Luntzer, M.; Sinske, D.; Ignatius, A.; Roselli, F.; Knoell, B.
Neuroinflammation after traumatic brain injury (TBI) is enhanced in activating transcription factor 3 (ATF3) mutant mice
J Neurotrauma, 35 (19) :2317–2329
2018
DOI:10.1089/neu.2017.5593
712.
Kovtun, A.; Messerer, D. A. C.; Scharffetter-Kochanek, K.; Huber-Lang, M.; Ignatius, A.
Neutrophils in Tissue Trauma of the Skin, Bone, and Lung: Two Sides of the Same Coin
J Immunol Res, 2018 :8173983
2018
DOI:10.1155/2018/8173983
711.
Ignatius, A.; Tuckermann, J.
New horizons for osteoanabolic treatment?
Nat Rev Endocrinol, 14 (9) :508–509
2018
DOI:10.1038/s41574-018-0069-2
710.
Kaiser, K.; Prystaz, K.; Vikman, A.; Haffner-Luntzer, M.; Bergdolt, S.; Strauss, G.; Waetzig, G. H.; Rose-John, S.; Ignatius, A.
Pharmacological inhibition of IL-6 trans-signaling improves compromised fracture healing after severe trauma
Naunyn Schmiedebergs Arch Pharmacol, 391 (5) :523–536
2018
DOI:10.1007/s00210-018-1483-7
709.
Modinger, Y.; Teixeira, G.; Neidlinger-Wilke, C.; Ignatius, A.
Role of the Complement System in the Response to Orthopedic Biomaterials
Int J Mol Sci, 19 (11) :3367
2018
DOI:10.3390/ijms19113367
708.
Niemeyer, F.; Claes, L.; Ignatius, A.; Meyers, N.; Simon, U.
Simulating lateral distraction osteogenesis
PLoS One, 13 (3) :e0194500
2018
DOI:10.1371/journal.pone.0194500
707.
Riegger, J.; Joos, H.; Palm, H. G.; Friemert, B.; Reichel, H.; Ignatius, A.; Brenner, R. E.
Striking a new path in reducing cartilage breakdown: combination of antioxidative therapy and chondroanabolic stimulation after blunt cartilage trauma
J Cell Mol Med, 22 (1) :77–88
2018
DOI:10.1111/jcmm.13295
706.
Reitmaier, S.; Kovtun, A.; Schuelke, J.; Kanter, B.; Lemm, M.; Hoess, A.; Heinemann, S.; Nies, B.; Ignatius, A.
Strontium(II) and mechanical loading additively augment bone formation in calcium phosphate scaffolds
J Orthop Res, 36 (1) :106–117
2018
DOI:10.1002/jor.23623
705.
Liebsch, C.; Graf, N.; Wilke, H.-J.
The effect of follower load on the intersegmental coupled motion characteristics of the human thoracic spine: An in vitro study using entire rib cage specimens
J Biomech, 78 :36–44
2018
DOI:10.1016/j.jbiomech.2018.06.025
704.
Claes, L.; Meyers, N.; Schulke, J.; Reitmaier, S.; Klose, S.; Ignatius, A.
The mode of interfragmentary movement affects bone formation and revascularization after callus distraction
PLoS One, 13 (8) :e0202702
2018
DOI:10.1371/journal.pone.0202702
703.
Langgartner, D.; Vaihinger, C. A.; Haffner-Luntzer, M.; Kunze, J. F.; Weiss, A.-L. J.; Foertsch, S.; Bergdolt, S.; Ignatius, A.; Reber, S. O.
The Role of the Intestinal Microbiome in Chronic Psychosocial Stress-Induced Pathologies in Male Mice
Front Behav Neurosci, 12 (252)
2018
DOI:10.3389/fnbeh.2018.00252
702.
Galbusera, F.; Qian, Z.; Casaroli, G.; Bassani, T.; Costa, F.; Schlager, B.; Wilke, H. J.
The Role of the Size and Location of the Tumors and of the Vertebral Anatomy in Determining the Structural Stability of the Metastatically Involved Spine: a Finite Element Study
Transl Oncol, 11 (3) :639–646
2018
DOI:10.1016/j.tranon.2018.03.002
701.
Sharabi, M.; Wade, K. R.; Galbusera, F.; Rasche, V.; Haj-Ali, R.; Wilke, H. J.
Three- dimensional microstructural reconstruction of the ovine intervertebral disc using ultra-high field MRI
Spine J, 18 (11) :2119–2127
2018
DOI:10.1016/j.spinee.2018.06.356
700.
Schlager, B.; Niemeyer, F.; Galbusera, F.; Volkheimer, D.; Jonas, R.; Wilke, H. J.
Uncertainty analysis of material properties and morphology parameters in numerical models regarding the motion of lumbar vertebral segments
Comput Methods Biomech Biomed Engin, 21 :673–683
2018
DOI:10.1080/10255842.2018.1508571

2017

699.
Claes, L.
[Mechanobiology of fracture healing part 1 : Principles]
Unfallchirurg, 120 (1) :14–22
2017
DOI:10.1007/s00113-016-0280-3
698.
Claes, L.
[Mechanobiology of fracture healing part 2 : Relevance for internal fixation of fractures]
Unfallchirurg, 120 (1) :23–31
2017
DOI:10.1007/s00113-016-0281-2
697.
Haj-Ali, R.; Massarwa, E.; Aboudi, J.; Galbusera, F.; Wolfram, U.; Wilke, H. J.
A new multiscale micromechanical model of vertebral trabecular bones
Biomech Model Mechanobiol, 16 (3) :933–946
2017
DOI:10.1007/s10237-016-0862-6
696.
Massarwa, E.; Aboudi, J.; Galbusera, F.; Wilke, H. J.; Haj-Ali, R.
A nonlinear micromechanical model for progressive damage of vertebral trabecular bones
J Mech Mater Struct, 12 (4) :407–424
2017
DOI:10.2140/jomms.2017.12.407
695.
Casaroli, G.; Galbusera, F.; Jonas, R.; Schlager, B.; Wilke, H. J.; Villa, T.
A novel finite element model of the ovine lumbar intervertebral disc with anisotropic hyperelastic material properties
PLoS One, 12 (5) :e0177088
2017
DOI:10.1371/journal.pone.0177088
694.
Drews, B. H.; Seitz, A. M.; Huth, J.; Bauer, G.; Ignatius, A.; Dürselen, L.
ACL double-bundle reconstruction with one tibial tunnel provides equal stability compared to two tibial tunnels
Knee Surg Sports Traumatol Arthrosc, 25 (5) :1646–1652
2017
DOI:10.1007/s00167-016-4199-6
693.
Achatz, G.; Riesner, H. J.; Friemert, B.; Lechner, R.; Graf, N.; Wilke, H. J.
Biomechanical in vitro comparison of radiofrequency kyphoplasty and balloon kyphoplasty
Eur Spine J, 26 (12) :3225–3234
2017
DOI:10.1007/s00586-017-5035-5
692.
Fischer, V.; Haffner-Luntzer, M.; Prystaz, K.; Scheidt, A. V.; Busse, B.; Schinke, T.; Amling, M.; Ignatius, A.
Calcium and vitamin-D deficiency marginally impairs fracture healing but aggravates posttraumatic bone loss in osteoporotic mice
Sci Rep, 7 (1) :7223
2017
DOI:10.1038/s41598-017-07511-2
691.
Meyers, N.; Sukopp, M.; Jager, R.; Steiner, M.; Matthys, R.; Lapatki, B.; Ignatius, A.; Claes, L.
Characterization of interfragmentary motion associated with common osteosynthesis devices for rat fracture healing studies
PLoS One, 12 (4) :e0176735
2017
DOI:10.1371/journal.pone.0176735
690.
Foertsch, S.; Haffner-Luntzer, M.; Kroner, J.; Gross, F.; Kaiser, K.; Erber, M.; Reber, S. O.; Ignatius, A.
Chronic psychosocial stress disturbs long-bone growth in adolescent mice
Dis Model Mech, 10 (12) :1399–1409
2017
DOI:10.1242/dmm.030916
689.
Denk, S.; Neher, M. D.; Messerer, D. A. C.; Wiegner, R.; Nilsson, B.; Rittirsch, D.; Nilsson-Ekdahl, K.; Weckbach, S.; Ignatius, A.; Kalbitz, M.; Gebhard, F.; Weiss, M. E.; Vogt, J.; Radermacher, P.; Kohl, J.; Lambris, J. D.; Huber-Lang, M. S.
Complement C5a Functions as a Master Switch for the pH Balance in Neutrophils Exerting Fundamental Immunometabolic Effects
J Immunol, 198 (12) :4846–4854
2017
DOI:10.4049/jimmunol.1700393
688.
Kovtun, A.; Bergdolt, S.; Hagele, Y.; Matthes, R.; Lambris, J. D.; Huber-Lang, M.; Ignatius, A.
Complement receptors C5aR1 and C5aR2 act differentially during the early immune response after bone fracture but are similarly involved in bone repair
Sci Rep, 7 (1) :14061
2017
DOI:10.1038/s41598-017-14444-3
687.
Giudici, F.; Galbusera, F.; Zagra, A.; Wilke, H. J.; Archetti, M.; Scaramuzzo, L.
Determinants of the biomechanical and radiological outcome of surgical correction of adolescent idiopathic scoliosis surgery: the role of rod properties and patient characteristics
Eur Spine J, 26 (Suppl 4) :S524–S532
2017
DOI:10.1007/s00586-017-5148-x
686.
Plener, P. L.; Ignatius, A.; Huber-Lang, M.; Fegert, J. M.
Die Auswirkungen von Missbrauch, Misshandlung und Vernachlässigung im Kindesalter auf die psychische und physische Gesundheit im Erwachsenenalter
Nervenheilkunde, 36 (3) :161–167
2017
DOI:10.1055/s-0038-1635151
685.
Seefried, L.; Mueller-Deubert, S.; Krug, M.; Youssef, A.; Schuetze, N.; Ignatius, A.; Jakob, F.; Ebert, R.
Dissection of mechanoresponse elements in promoter sites of the mechanoresponsive CYR61 gene
Exp Cell Res, 354 (2) :103–111
2017
DOI:10.1016/j.yexcr.2017.03.031
684.
Haffner-Luntzer, M.; Muller-Graf, F.; Matthys, R.; Hagele, Y.; Fischer, V.; Jonas, R.; Abaei, A.; Gebhard, F.; Rasche, V.; Ignatius, A.
Evaluation of high-resolution In Vivo MRI for longitudinal analysis of endochondral fracture healing in mice
PLoS One, 12 (3) :e0174283
2017
DOI:10.1371/journal.pone.0174283
683.
Wilkening, A.; Hacker, S.; Stöppler, H.; Dürselen, L.; Ivlev, O.
Experimental and Simulation-Based Investigation of Polycentric Motion of an Inherent Compliant Pneumatic Bending Actuator with Skewed Rotary Elastic Chambers
Robotics, 6 (1) :2
2017
DOI:10.3390/robotics6010002
682.
Warnecke, D.; Schild, N. B.; Klose, S.; Joos, H.; Brenner, R. E.; Kessler, O.; Skaer, N.; Walker, R.; Freutel, M.; Ignatius, A.; Dürselen, L.
Friction properties of a new silk fibroin scaffold for meniscal replacement
Tribol Int, 109 :586–592
2017
DOI:10.1016/j.triboint.2017.01.038
681.
Drews, B. H.; Kessler, O.; Franz, W.; Dürselen, L.; Freutel, M.
Function and strain of the anterolateral ligament part I: biomechanical analysis
Knee Surg Sports Traumatol Arthrosc, 25 (4) :1132–1139
2017
DOI:10.1007/s00167-017-4472-3
680.
Wanner, R.; Gey, M.; Abaei, A.; Warnecke, D.; Roy, L.; Dürselen, L.; Rasche, V.; Knöll, B.
Functional and Molecular Characterization of a Novel Traumatic Peripheral Nerve-Muscle Injury Model
Neuromolecular Med, 19 (2-3) :357–374
2017
DOI:10.1007/s12017-017-8450-1
679.
Wilke, H. J.; Herkommer, A.; Werner, K.; Liebsch, C.
In vitro analysis of the segmental flexibility of the thoracic spine
PLoS One, 12 (5) :e0177823
2017
DOI:10.1371/journal.pone.0177823
678.
Haffner-Luntzer, M.; Muller-Graf, F.; Matthys, R.; Abaei, A.; Jonas, R.; Gebhard, F.; Rasche, V.; Ignatius, A.
In Vivo Evaluation of Fracture Callus Development During Bone Healing in Mice Using an MRI-compatible Osteosynthesis Device for the Mouse Femur
J Vis Exp (129) :e56679
2017
DOI:10.3791/56679
677.
Berger-Roscher, N.; Casaroli, G.; Rasche, V.; Villa, T.; Galbusera, F.; Wilke, H. J.
Influence of Complex Loading Conditions on Intervertebral Disc Failure
Spine (Phila Pa 1976), 42 (2) :E78–E85
2017
DOI:10.1097/BRS.0000000000001699
676.
Drews, B. H.; Seitz, A.; Huth, J.; Bauer, G.; Ignatius, A.; Dürselen, L.
Influence of tibial hybrid fixation on graft tension and stability in ACL double-bundle reconstruction
Arch Orthop Trauma Surg, 137 (7) :981–988
2017
DOI:10.1007/s00402-017-2698-7
675.
Volkheimer, D.; Reichel, H.; Wilke, H. J.; Lattig, F.
Is pelvic fixation the only option to provide additional stability to the sacral anchorage in long lumbar instrumentation? A comparative biomechanical study of new techniques
Clin Biomech (Bristol, Avon), 43 :34–39
2017
DOI:10.1016/j.clinbiomech.2017.02.001
674.
Kroner, J.; Kovtun, A.; Kemmler, J.; Messmann, J. J.; Strauss, G.; Seitz, S.; Schinke, T.; Amling, M.; Kotrba, J.; Dudeck, J.; Dudeck, A.; Ignatius, A.
Mast cells are critical regulators of bone fracture-induced inflammation and osteoclast formation and activity
J Bone Miner Res, 32 (12) :2431–2444
2017
DOI:10.1002/jbmr.3234
673.
Blum, C.; Brückner, T.; Ewald, A.; Ignatius, A.; Gbureck, U.
Mg:Ca ratio as regulating factor for osteoclastic in vitro resorption of struvite biocements
Mater Sci Eng C, 73 :111–119
2017
DOI:10.1016/j.msec.2016.12.002
672.
Rijsbergen, M. M.; Barthelemy, V. M.; Vrancken, A. C.; Crijns, S. P.; Wilke, H. J.; Wilson, W.; Rietbergen, B.; Ito, K.
Moderately degenerated lumbar motion segments: Are they truly unstable?
Biomech Model Mechanobiol, 16 (2) :537–547
2017
DOI:10.1007/s10237-016-0835-9
671.
Bartnikowski, N.; Claes, L. E.; Koval, L.; Glatt, V.; Bindl, R.; Steck, R.; Ignatius, A.; Schuetz, M. A.; Epari, D. R.
Modulation of fixation stiffness from flexible to stiff in a rat model of bone healing
Acta Orthop, 88 (2) :217–222
2017
DOI:10.1080/17453674.2016.1256940
670.
Meyers, N.; Schulke, J.; Ignatius, A.; Claes, L.
Novel systems for the application of isolated tensile, compressive, and shearing stimulation of distraction callus tissue
PLoS One, 12 (12) :e0189432
2017
DOI:10.1371/journal.pone.0189432
669.
Casaroli, G.; Villa, T.; Bassani, T.; Berger-Roscher, N.; Wilke, H.-J.; Galbusera, F.
Numerical Prediction of the Mechanical Failure of the Intervertebral Disc under Complex Loading Conditions
Materials, 10 (1) :31
2017
DOI:10.3390/ma10010031
668.
Bergdolt, S.; Kovtun, A.; Hagele, Y.; Liedert, A.; Schinke, T.; Amling, M.; Huber-Lang, M.; Ignatius, A.
Osteoblast-specific overexpression of complement receptor C5aR1 impairs fracture healing
PLoS One, 12 (6) :e0179512
2017
DOI:10.1371/journal.pone.0179512
667.
El Khassawna, T.; Merboth, F.; Malhan, D.; Bocker, W.; Daghma, D. E. S.; Stoetzel, S.; Kern, S.; Hassan, F.; Rosenbaum, D.; Langenstein, J.; Bauer, N.; Schlagenhauf, A.; Rosen-Wolff, A.; Schulze, F.; Rupp, M.; Hose, D.; Secklinger, A.; Ignatius, A.; Wilke, H. J.; Lips, K. S.; Heiss, C.
Osteocyte Regulation of Receptor Activator of NF-kappaB Ligand/Osteoprotegerin in a Sheep Model of Osteoporosis
Am J Pathol, 187 (8) :1686–1699
2017
DOI:10.1016/j.ajpath.2017.04.005
666.
Meininger, S.; Blum, C.; Schamel, M.; Barralet, J. E.; Ignatius, A.; Gbureck, U.
Phytic acid as alternative setting retarder enhanced biological performance of dicalcium phosphate cement in vitro
Sci Rep, 7 (1) :558
2017
DOI:10.1038/s41598-017-00731-6
665.
La Barbera, L.; Galbusera, F.; Wilke, H. J.; Villa, T.
Preclinical evaluation of posterior spine stabilization devices: can we compare in vitro and in vivo loads on the instrumentation?
Eur Spine J, 26 (1) :200–209
2017
DOI:10.1007/s00586-016-4766-z
664.
Bassani, T.; Ottardi, C.; Costa, F.; Brayda-Bruno, M.; Wilke, H.-J.; Galbusera, F.
Semiautomated 3D Spine Reconstruction from Biplanar Radiographic Images: Prediction of Intervertebral Loading in Scoliotic Subjects
Front Bioeng Biotechnol, 5 (1)
2017
DOI:10.3389/fbioe.2017.00001
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Oheim, R.; Simon, M. J.; Steiner, M.; Vettorazzi, E.; Barvencik, F.; Ignatius, A.; Amling, M.; Clarke, I. J.; Pogoda, P.; Beil, F. T.
Sheep model for osteoporosis: The effects of peripheral hormone therapy on centrally induced systemic bone loss in an osteoporotic sheep model
Injury, 48 (4) :841–848
2017
DOI:10.1016/j.injury.2017.02.009
662.
Gačanin, J.; Kovtun, A.; Fischer, S.; Schwager, V.; Quambusch, J.; Kuan, S. L.; Liu, W.; Boldt, F.; Li, C.; Yang, Z.; Liu, D.; Wu, Y.; Weil, T.; Barth, H.; Ignatius, A.
Spatiotemporally Controlled Release of Rho-Inhibiting C3 Toxin from a Protein–DNA Hybrid Hydrogel for Targeted Inhibition of Osteoclast Formation and Activity
Adv Healthc Mater, 6 (21) :1700392
2017
DOI:10.1002/adhm.201700392
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Reitmaier, S.; Schuelke, J.; Schmidt, H.; Volkheimer, D.; Ignatius, A.; Wilke, H. J.
Spinal fusion without instrumentation - Experimental animal study
Clin Biomech (Bristol, Avon), 46 :6–14
2017
DOI:10.1016/j.clinbiomech.2017.04.008
660.
Dex, S.; Alberton, P.; Willkomm, L.; Sollradl, T.; Bago, S.; Milz, S.; Shakibaei, M.; Ignatius, A.; Bloch, W.; Clausen-Schaumann, H.; Shukunami, C.; Schieker, M.; Docheva, D.
Tenomodulin is Required for Tendon Endurance Running and Collagen I Fibril Adaptation to Mechanical Load
EBioMedicine, 20 :240–254
2017
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659.
Claes, L.; Gebhard, F.; Ignatius, A.; Lechner, R.; Baumgartel, S.; Kraus, M.; Krischak, G. D.
The effect of a combined thoracic and soft-tissue trauma on blood flow and tissue formation in fracture healing in rats
Arch Orthop Trauma Surg, 137 (7) :945–952
2017
DOI:10.1007/s00402-017-2695-x
658.
Haffner-Luntzer, M.; Fischer, V.; Prystaz, K.; Liedert, A.; Ignatius, A.
The inflammatory phase of fracture healing is influenced by oestrogen status in mice
Eur J Med Res, 33 (1) :23
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657.
Liebsch, C.; Graf, N.; Appelt, K.; Wilke, H. J.
The rib cage stabilizes the human thoracic spine: An in vitro study using stepwise reduction of rib cage structures
PLoS One, 12 (6) :e0178733
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Ehrnthaller, C.; Olivier, A. C.; Gebhard, F.; Dürselen, L.
The role of lesser trochanter fragment in unstable pertrochanteric A2 proximal femur fractures - is refixation of the lesser trochanter worth the effort?
Clin Biomech (Bristol, Avon), 42 (1) :31–37
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Wilke, H. J.; Volkheimer, D.; Robie, B.; Christensen, F. B.
Two-piece ALIF cage optimizes the bone-implant interface in a 360 degrees setting
Eur Spine J, 26 (11) :2747??2753
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654.
Rolvien, T.; Hahn, M.; Siebert, U.; Püschel, K.; Wilke, H. J.; Busse, B.; Amling, M.; Oheim, R.
Vertebral bone microarchitecture and osteocyte characteristics of three toothed whale species with varying diving behaviour
Sci Rep, 7 (1) :1604
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653.
Liebsch, C.; Graf, N.; Wilke, H. J.
Wire cerclage can restore the stability of the thoracic spine after median sternotomy: an in vitro study with entire rib cage specimens
Eur Spine J, 26 (5) :1401–1407
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DOI:10.1007/s00586-016-4768-x

2016

652.
Teixeira, G. Q.; Boldt, A.; Nagl, I.; Pereira, C. L.; Benz, K.; Wilke, H. J.; Ignatius, A.; Barbosa, M. A.; Goncalves, R. M.; Neidlinger-Wilke, C.
A Degenerative/Proinflammatory Intervertebral Disc Organ Culture: An Ex Vivo Model for Anti-inflammatory Drug and Cell Therapy
Tissue Eng Part C Methods, 22 (1) :8–19
2016
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651.
Wilke, H. J.; Kienle, A.; Maile, S.; Rasche, V.; Berger-Roscher, N.
A new dynamic six degrees of freedom disc-loading simulator allows to provoke disc damage and herniation
Eur Spine J, 25 (5) :1363–72
2016
DOI:10.1007/s00586-016-4416-5
650.
Wilke, H. J.; Kaiser, D.; Volkheimer, D.; Hackenbroch, C.; Püschel, K.; Rauschmann, M.
A pedicle screw system and a lamina hook system provide similar primary and long-term stability: a biomechanical in vitro study with quasi-static and dynamic loading conditions
Eur Spine J, 25 (9) :2919–2928
2016
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649.
Haffner-Luntzer, M.; Heilmann, A.; Rapp, A. E.; Roessler, R.; Schinke, T.; Amling, M.; Ignatius, A.; Liedert, A.
Antagonizing Midkine Accelerates Fracture Healing in Mice by Enhanced Bone Formation in the Fracture Callus
Br J Pharmacol, 173 (14) :2237–49
2016
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648.
Teixeira, G. Q.; Leite Pereira, C.; Castro, F.; Ferreira, J. R.; Gomez-Lazaro, M.; Aguiar, P.; Barbosa, M. A.; Neidlinger-Wilke, C.; Goncalves, R. M.
Anti-inflammatory Chitosan/Poly-gamma-glutamic acid nanoparticles control inflammation while remodeling extracellular matrix in degenerated intervertebral disc
Acta Biomater, 42 :168–179
2016
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647.
Riegger, J.; Joos, H.; Palm, H. G.; Friemert, B.; Reichel, H.; Ignatius, A.; Brenner, R. E.
Antioxidative therapy in an ex vivo human cartilage trauma-model: Attenuation of trauma-induced cell loss and ECM-destructive enzymes by N-acetyl cysteine
Osteoarthritis Cartilage, 24 (12) :2171–2180
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646.
Ehrnthaller, C.; Huber-Lang, M.; Kovtun, A.; Rapp, A. E.; Kemmler, J.; Gebhard, F.; Ignatius, A.
C5aR inhibition in the early inflammatory phase does not affect bone regeneration in a model of uneventful fracture healing
Eur J Med Res, 21 (1) :42
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645.
Pratsinis, H.; Papadopoulou, A.; Neidlinger-Wilke, C.; Brayda-Bruno, M.; Wilke, H. J.; Kletsas, D.
Cyclic tensile stress of human annulus fibrosus cells induces MAPK activation: involvement in proinflammatory gene expression
Osteoarthritis Cartilage, 24 (4) :679–87
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Simon, M. J.; Beil, F. T.; Riedel, C.; Lau, G.; Tomsia, A.; Zimmermann, E. A.; Koehne, T.; Ueblacker, P.; Ruther, W.; Pogoda, P.; Ignatius, A.; Amling, M.; Oheim, R.
Deterioration of teeth and alveolar bone loss due to chronic environmental high-level fluoride and low calcium exposure
Clin Oral Investig, 20 (9) :2361–2370
2016
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Belavy, D. L.; Adams, M.; Brisby, H.; Cagnie, B.; Danneels, L.; Fairbank, J.; Hargens, A. R.; Judex, S.; Scheuring, R. A.; Sovelius, R.; Urban, J.; Dieen, J. H.; Wilke, H. J.
Disc herniations in astronauts: What causes them, and what does it tell us about herniation on earth?
Eur Spine J, 25 (1) :144–154
2016
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Kienle, A.; Graf, N.; Wilke, H. J.
Does impaction of titanium-coated interbody fusion cages into the disc space cause wear debris and/or delamination?
Spine J, 16 :2
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Müller, S. A.; Dürselen, L.; Heisterbach, P.; Evans, C.; Majewski, M.
Effect of a Simple Collagen Type I Sponge for Achilles Tendon Repair in a Rat Model
Am J Sports Med, 44 (8) :1998–2004
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Ray, S.; Thormann, U.; Sommer, U.; Khassawna, T. E.; Hundgeburth, M.; Henss, A.; Rohnke, M.; Lips, K. S.; Heiss, C.; Heinemann, S.; Hanke, T.; Dürselen, L.; Schnettler, R.; Alt, V.
Effects of macroporous, strontium loaded xerogel-scaffolds on new bone formation in critical-size metaphyseal fracture defects in ovariectomized rats
Injury, 47 Suppl 1 :S52–61
2016
DOI:10.1016/S0020-1383(16)30013-4

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