Publications

You find here a complete list of publications authored or coauthered by members of our institute since 1974. By default the entire list is presented.

2017

777.
Meininger, S.; Blum, C.; Schamel, M.; Barralet, J. E.; Ignatius, A.; Gbureck, U.
Phytic acid as alternative setting retarder enhanced biological performance of dicalcium phosphate cement in vitro
Sci Rep, 7 (1) :558
2017
DOI:10.1038/s41598-017-00731-6
File:https://www.ncbi.nlm.nih.gov/pubmed/28373697

2017

776.
La Barbera, L.; Galbusera, F.; Wilke, H. J.; Villa, T.
Preclinical evaluation of posterior spine stabilization devices: can we compare in vitro and in vivo loads on the instrumentation?
Eur Spine J, 26 (1) :200-209
2017
DOI:10.1007/s00586-016-4766-z
File:http://www.ncbi.nlm.nih.gov/pubmed/27637903
775.
Liebsch, C.; Graf, N.; Appelt, K.; Wilke, H. J.
The rib cage stabilizes the human thoracic spine: An in vitro study using stepwise reduction of rib cage structures
PLoS One, 12 (6) :e0178733
2017
DOI:10.1371/journal.pone.0178733
File:https://www.ncbi.nlm.nih.gov/pubmed/28570671
774.
Oheim, R.; Simon, M. J.; Steiner, M.; Vettorazzi, E.; Barvencik, F.; Ignatius, A.; Amling, M.; Clarke, I. J.; Pogoda, P.; Beil, F. T.
Sheep model for osteoporosis: The effects of peripheral hormone therapy on centrally induced systemic bone loss in an osteoporotic sheep model
Injury, 48 (4) :841-848
2017
DOI:10.1016/j.injury.2017.02.009
File:http://www.ncbi.nlm.nih.gov/pubmed/28237183
773.
Gačanin, Jasmina; Kovtun, Anna; Schwager, Victoria; Quambusch, Johanna; Li, Chuang; Yang, Zhongqiang; Liu, Dongsheng
Spatiotemporally Controlled Release of Rho-Inhibiting C3 Toxin from a Protein–DNA Hybrid Hydrogel for Targeted Inhibition of Osteoclast Formation and Activity
Adv Healthc Mater, 6 (21) :1700392
2017
DOI:10.1002/adhm.201700392
File:http://dx.doi.org/10.1002/adhm.201700392
772.
Reitmaier, S.; Schuelke, J.; Schmidt, H.; Volkheimer, D.; Ignatius, A.; Wilke, H. J.
Spinal fusion without instrumentation - Experimental animal study
Clin Biomech (Bristol, Avon), 46 :6-14
2017
DOI:10.1016/j.clinbiomech.2017.04.008
File:https://www.ncbi.nlm.nih.gov/pubmed/28463696
771.
Dex, S.; Alberton, P.; Willkomm, L.; Sollradl, T.; Bago, S.; Milz, S.; Shakibaei, M.; Ignatius, A.; Bloch, W.; Clausen-Schaumann, H.; Shukunami, C.; Schieker, M.; Docheva, D.
Tenomodulin is Required for Tendon Endurance Running and Collagen I Fibril Adaptation to Mechanical Load
EBioMedicine, 20 :240-254
2017
DOI:10.1016/j.ebiom.2017.05.003
File:https://www.ncbi.nlm.nih.gov/pubmed/28566251
770.
Claes, L.; Gebhard, F.; Ignatius, A.; Lechner, R.; Baumgartel, S.; Kraus, M.; Krischak, G. D.
The effect of a combined thoracic and soft-tissue trauma on blood flow and tissue formation in fracture healing in rats
Arch Orthop Trauma Surg, 137 (7) :945-952
2017
DOI:10.1007/s00402-017-2695-x
File:https://www.ncbi.nlm.nih.gov/pubmed/28429082
769.
Haffner-Luntzer, M; Fischer, V.; Prystaz, K.; Liedert, A.; Ignatius, A
The inflammatory phase of fracture healing is influenced by oestrogen status in mice
Eur J Med Res, 33 (1) :23
2017
DOI:DOI 10.1186/s40001‐017‐0264‐y
768.
Ehrnthaller, C.; Olivier, A. C.; Gebhard, F.; Dürselen, L.
The role of lesser trochanter fragment in unstable pertrochanteric A2 proximal femur fractures - is refixation of the lesser trochanter worth the effort?
Clin Biomech (Bristol, Avon), 42 (1) :31-37
2017
DOI:10.1016/j.clinbiomech.2016.12.013
File:https://www.ncbi.nlm.nih.gov/pubmed/28073094
767.
Wilke, H. J.; Volkheimer, D.; Robie, B.; Christensen, F. B.
Two-piece ALIF cage optimizes the bone-implant interface in a 360 degrees setting
Eur Spine J, 26 (11) :2747-2753
2017
DOI:10.1007/s00586-017-5009-7
File:http://www.ncbi.nlm.nih.gov/pubmed/28247079
766.
Rolvien, T.; Hahn, M.; Siebert, U.; Puschel, K.; Wilke, H. J.; Busse, B.; Amling, M.; Oheim, R.
Vertebral bone microarchitecture and osteocyte characteristics of three toothed whale species with varying diving behaviour
Sci Rep, 7 (1) :1604
2017
DOI:10.1038/s41598-017-01926-7
File:https://www.ncbi.nlm.nih.gov/pubmed/28487524
765.
Liebsch, C.; Graf, N.; Wilke, H. J.
Wire cerclage can restore the stability of the thoracic spine after median sternotomy: an in vitro study with entire rib cage specimens
Eur Spine J, 26 (5) :1401-1407
2017
DOI:10.1007/s00586-016-4768-x
File:http://www.ncbi.nlm.nih.gov/pubmed/27639711
764.
Volkheimer, D.; Reichel, H.; Wilke, H. J.; Lattig, F.
Is pelvic fixation the only option to provide additional stability to the sacral anchorage in long lumbar instrumentation? A comparative biomechanical study of new techniques
Clin Biomech (Bristol, Avon), 43 :34-39
2017
DOI:10.1016/j.clinbiomech.2017.02.001
File:https://www.ncbi.nlm.nih.gov/pubmed/28199880
763.
Kroner, J.; Kovtun, A.; Kemmler, J.; Messmann, J. J.; Strauss, G.; Seitz, S.; Schinke, T.; Amling, M.; Kotrba, J.; Dudeck, J.; Dudeck, A.; Ignatius, A.
Mast cells are critical regulators of bone fracture-induced inflammation and osteoclast formation and activity
J Bone Miner Res, 32 (12) :2431–2444
2017
DOI:10.1002/jbmr.3234
File:https://www.ncbi.nlm.nih.gov/pubmed/28777474
762.
Wilke, H. J.; Herkommer, A.; Werner, K.; Liebsch, C.
In vitro analysis of the segmental flexibility of the thoracic spine
PLoS One, 12 (5) :e0177823
2017
DOI:10.1371/journal.pone.0177823
File:https://www.ncbi.nlm.nih.gov/pubmed/28520819
761.
Drews, B. H.; Seitz, A.; Huth, J.; Bauer, G.; Ignatius, A.; Dürselen, L.
Influence of tibial hybrid fixation on graft tension and stability in ACL double-bundle reconstruction
Arch Orthop Trauma Surg, 137 (7) :981–988
2017
DOI:10.1007/s00402-017-2698-7
File:https://www.ncbi.nlm.nih.gov/pubmed/28424860
760.
Kovtun, A.; Bergdolt, S.; Hagele, Y.; Matthes, R.; Lambris, J. D.; Huber-Lang, M.; Ignatius, A.
Complement receptors C5aR1 and C5aR2 act differentially during the early immune response after bone fracture but are similarly involved in bone repair
Sci Rep, 7 (1) :14061
2017
DOI:10.1038/s41598-017-14444-3
File:pdfhttps://www.ncbi.nlm.nih.gov/pubmed/29070810 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5656620/pdf/41598_2017_Article_14444.pdf
759.
Berger-Roscher, N.; Casaroli, G.; Rasche, V.; Villa, T.; Galbusera, F.; Wilke, H. J.
Influence of Complex Loading Conditions on Intervertebral Disc Failure
Spine (Phila Pa 1976), 42 (2) :E78-E85
2017
DOI:10.1097/BRS.0000000000001699
File:http://www.ncbi.nlm.nih.gov/pubmed/27187053
758.
Claes, L.
[Mechanobiology of fracture healing part 2 : Relevance for internal fixation of fractures]
Unfallchirurg, 120 (1) :23-31
2017
DOI:10.1007/s00113-016-0281-2
File:https://www.ncbi.nlm.nih.gov/pubmed/27975121
757.
Haj-Ali, R.; Massarwa, E.; Aboudi, J.; Galbusera, F.; Wolfram, U.; Wilke, H. J.
A new multiscale micromechanical model of vertebral trabecular bones
Biomech Model Mechanobiol, 16 (3) :933-946
2017
DOI:10.1007/s10237-016-0862-6
File:https://www.ncbi.nlm.nih.gov/pubmed/27913902
756.
Massarwa, E.; Aboudi, J.; Galbusera, F.; Wilke, H. J.; Haj-Ali, R.
A nonlinear micromechanical model for progressive damage of vertebral trabecular bones
J Mech Mater Struct, 12 (4) :407-424
2017
DOI:DOI: 10.2140/jomms.2017.12.407
755.
Casaroli, G.; Galbusera, F.; Jonas, R.; Schlager, B.; Wilke, H. J.; Villa, T.
A novel finite element model of the ovine lumbar intervertebral disc with anisotropic hyperelastic material properties
PLoS One, 12 (5) :e0177088
2017
DOI:10.1371/journal.pone.0177088
File:https://www.ncbi.nlm.nih.gov/pubmed/28472100
754.
Drews, B. H.; Seitz, A. M.; Huth, J.; Bauer, G.; Ignatius, A.; Dürselen, L.
ACL double-bundle reconstruction with one tibial tunnel provides equal stability compared to two tibial tunnels
Knee Surg Sports Traumatol Arthrosc, 25 (5) :1646-1652
2017
DOI:10.1007/s00167-016-4199-6
File:http://www.ncbi.nlm.nih.gov/pubmed/27295057
753.
Achatz, G.; Riesner, H. J.; Friemert, B.; Lechner, R.; Graf, N.; Wilke, H. J.
Biomechanical in vitro comparison of radiofrequency kyphoplasty and balloon kyphoplasty
Eur Spine J, 26 (12) :3225-3234
2017
DOI:10.1007/s00586-017-5035-5
File:https://www.ncbi.nlm.nih.gov/pubmed/28451858
752.
Meyers, N.; Sukopp, M.; Jager, R.; Steiner, M.; Matthys, R.; Lapatki, B.; Ignatius, A.; Claes, L.
Characterization of interfragmentary motion associated with common osteosynthesis devices for rat fracture healing studies
PLoS One, 12 (4) :e0176735
2017
DOI:10.1371/journal.pone.0176735
File:https://www.ncbi.nlm.nih.gov/pubmed/28453556
751.
Foertsch, S.; Haffner-Luntzer, M.; Kroner, J.; Gross, F.; Kaiser, K.; Erber, M.; Reber, S. O.; Ignatius, A.
Chronic psychosocial stress disturbs long-bone growth in adolescent mice
Dis Model Mech, 10 (12) :1399-1409
2017
DOI:10.1242/dmm.030916
File:https://www.ncbi.nlm.nih.gov/pubmed/28982680
750.
Denk, S.; Neher, M. D.; Messerer, D. A. C.; Wiegner, R.; Nilsson, B.; Rittirsch, D.; Nilsson-Ekdahl, K.; Weckbach, S.; Ignatius, A.; Kalbitz, M.; Gebhard, F.; Weiss, M. E.; Vogt, J.; Radermacher, P.; Kohl, J.; Lambris, J. D.; Huber-Lang, M. S.
Complement C5a Functions as a Master Switch for the pH Balance in Neutrophils Exerting Fundamental Immunometabolic Effects
J Immunol, 198 (12) :4846-4854
2017
DOI:10.4049/jimmunol.1700393
File:https://www.ncbi.nlm.nih.gov/pubmed/28490576
749.
Fischer, V.; Haffner-Luntzer, M.; Prystaz, K.; Scheidt, A. V.; Busse, B.; Schinke, T.; Amling, M.; Ignatius, A.
Calcium and vitamin-D deficiency marginally impairs fracture healing but aggravates posttraumatic bone loss in osteoporotic mice
Sci Rep, 7 (1) :7223
2017
DOI:10.1038/s41598-017-07511-2
File:https://www.ncbi.nlm.nih.gov/pubmed/28775273
748.
Giudici, F.; Galbusera, F.; Zagra, A.; Wilke, H. J.; Archetti, M.; Scaramuzzo, L.
Determinants of the biomechanical and radiological outcome of surgical correction of adolescent idiopathic scoliosis surgery: the role of rod properties and patient characteristics
Eur Spine J, 26 (Suppl 4) :S524-S532
2017
DOI:10.1007/s00586-017-5148-x
File:https://www.ncbi.nlm.nih.gov/pubmed/28536946
747.
Warnecke, Daniela; Schild, N. B.; Klose, S.; Joos, H.; Brenner, R. E.; Kessler, O.; Skaer, N.; Walker, R.; Freutel, M.; Ignatius, A.; Dürselen, L.
Friction properties of a new silk fibroin scaffold for meniscal replacement
Tribol Int, 109 :586-592
2017
DOI:http://dx.doi.org/10.1016/j.triboint.2017.01.038
File://www.sciencedirect.com/science/article/pii/S0301679X17300452
746.
Plener, P.L.; Ignatius, A; Huber-Lang, M.; Fegert, J.M.
Die Auswirkungen von Missbrauch, Misshandlung und Vernachlässigung im Kindesalter auf die psychische und physische Gesundheit im Erwachsenenalter
Nervenheilkunde, 36 (3) :161-167
2017
745.
Claes, L.
[Mechanobiology of fracture healing part 1 : Principles]
Unfallchirurg, 120 (1) :14-22
2017
DOI:10.1007/s00113-016-0280-3
File:https://www.ncbi.nlm.nih.gov/pubmed/27966008
744.
Wanner, R.; Gey, M.; Abaei, A.; Warnecke, D.; Roy, L.; Dürselen, L.; Rasche, V.; Knöll, B.
Functional and Molecular Characterization of a Novel Traumatic Peripheral Nerve-Muscle Injury Model
Neuromolecular Med, 19 (2-3) :357-374
2017
DOI:10.1007/s12017-017-8450-1
File:https://www.ncbi.nlm.nih.gov/pubmed/28689354
743.
Drews, B. H.; Kessler, O.; Franz, W.; Dürselen, L.; Freutel, M.
Function and strain of the anterolateral ligament part I: biomechanical analysis
Knee Surg Sports Traumatol Arthrosc, 25 (4) :1132-1139
2017
DOI:10.1007/s00167-017-4472-3
File:http://www.ncbi.nlm.nih.gov/pubmed/28258329
742.
Haffner-Luntzer, M; Müller-Graf, F; Matthys, R.; Abaei, A; Jonas, R.; Gebhard, F.; Rasche, V.; Ignatius, A
In Vivo Evaluation of Fracture Callus Development During Bone Healing in Mice Using an MRI-compatible Osteosynthesis Device for the Mouse Femur
J Vis Exp (129) :e56679
2017
DOI:doi:10.3791/56679
741.
Wilkening, André; Hacker, Steffen; Stöppler, Henning; Dürselen, Lutz; Ivlev, Oleg
Experimental and Simulation-Based Investigation of Polycentric Motion of an Inherent Compliant Pneumatic Bending Actuator with Skewed Rotary Elastic Chambers
Robotics, 6 (1) :2
2017
File:http://www.mdpi.com/2218-6581/6/1/2
740.
Haffner-Luntzer, M.; Muller-Graf, F.; Matthys, R.; Hagele, Y.; Fischer, V.; Jonas, R.; Abaei, A.; Gebhard, F.; Rasche, V.; Ignatius, A.
Evaluation of high-resolution In Vivo MRI for longitudinal analysis of endochondral fracture healing in mice
PLoS One, 12 (3) :e0174283
2017
DOI:10.1371/journal.pone.0174283
File:https://www.ncbi.nlm.nih.gov/pubmed/28333972
739.
Haffner-Luntzer, M; Fischer, V.; Schinke, T.; Amling, M; Liedert, A.; Ignatius, A
Einfluss des pleiotrophen Signalmoleküls Midkine auf die Knochenheilung
Spitzenforschung Orthopädie und Unfallchirurgie, 18 :13-18
2017
738.
Seefried, L.; Mueller-Deubert, S.; Krug, M.; Youssef, A.; Schuetze, N.; Ignatius, A.; Jakob, F.; Ebert, R.
Dissection of mechanoresponse elements in promoter sites of the mechanoresponsive CYR61 gene
Exp Cell Res, 354 (2) :103-111
2017
DOI:10.1016/j.yexcr.2017.03.031
File:https://www.ncbi.nlm.nih.gov/pubmed/28322825

2016

737.
Rapp, A. E.; Bindl, R.; Recknagel, S.; Erbacher, A.; Muller, I.; Schrezenmeier, H.; Ehrnthaller, C.; Gebhard, F.; Ignatius, A.
Fracture Healing Is Delayed in Immunodeficient NOD/scidIL2Rgammacnull Mice
PLoS One, 11 (2) :e0147465
2016
DOI:10.1371/journal.pone.0147465
File:http://www.ncbi.nlm.nih.gov/pubmed/26849055
736.
Hacker, S. P.; Ignatius, A.; Dürselen, L.
The influence of the test setup on knee joint kinematics - A meta-analysis of tibial rotation
J Biomech, 49 (13) :2982-2988
2016
DOI:10.1016/j.jbiomech.2016.07.025
File:http://www.ncbi.nlm.nih.gov/pubmed/27507625
735.
Kovtun, A.; Bergdolt, S.; Wiegner, R.; Radermacher, P.; Huber-Lang, M.; Ignatius, A.
The crucial role of neutrophil granulocytes in bone fracture healing
Eur Cell Mater, 32 :152-62
2016
File:http://www.ncbi.nlm.nih.gov/pubmed/27452963
734.
Wilke, H. J.
Spine Research Is Multidisciplinary: 25 Years of Experiences
Spine (Phila Pa 1976), 41 Suppl 7 :S1-3
2016
DOI:10.1097/BRS.0000000000001419
File:http://www.ncbi.nlm.nih.gov/pubmed/27015056
733.
Malakoutian, M.; Street, J.; Wilke, H. J.; Stavness, I.; Dvorak, M.; Fels, S.; Oxland, T.
Role of muscle damage on loading at the level adjacent to a lumbar spine fusion: a biomechanical analysis
Eur Spine J, 25 (9) :2929-2937
2016
DOI:10.1007/s00586-016-4686-y
File:http://www.ncbi.nlm.nih.gov/pubmed/27465240
732.
Bieger, R.; Freitag, T.; Ignatius, A.; Reichel, H.; Dürselen, L.
Primary stability of a shoulderless Zweymuller hip stem: a comparative in vitro micromotion study
J Orthop Surg Res, 11 (1) :73
2016
DOI:10.1186/s13018-016-0410-1
File:http://www.ncbi.nlm.nih.gov/pubmed/27380777
731.
La Barbera, L.; Galbusera, F.; Wilke, H. J.; Villa, T.
Preclinical evaluation of posterior spine stabilization devices: can the current standards represent basic everyday life activities?
Eur Spine J, 25 (9) :2909-2918
2016
DOI:10.1007/s00586-016-4622-1
File:http://www.ncbi.nlm.nih.gov/pubmed/27236658
730.
Haffner-Luntzer, M.; Kovtun, A.; Rapp, A.; Ignatius, A
Mouse Models in Bone Fracture Healing Research
Curr Mol Biol Rep, 2 (2) :101-111
2016
DOI:10.1007/s40610-016-0037-3
729.
Haffner-Luntzer, M.; Liedert, A.; Ignatius, A
Mechanobiology of bone remodeling and fracture healing in the aged organism
Innov Surg Sci, 1 (2) :57-63
2016
DOI:DOI 10.1515/iss-2016-0021
728.
Haffner-Luntzer, M.; Kemmler, J.; Heidler, V.; Prystaz, K.; Schinke, T.; Amling, M.; Kovtun, A.; Rapp, A. E.; Ignatius, A.; Liedert, A.
Inhibition of Midkine Augments Osteoporotic Fracture Healing
PLoS One, 11 (7) :e0159278
2016
DOI:10.1371/journal.pone.0159278
File:http://www.ncbi.nlm.nih.gov/pubmed/27410432
727.
Haffner-Luntzer, M.; Heilmann, A.; Heidler, V.; Liedert, A.; Schinke, T.; Amling, M.; Yorgan, T. A.; Vom Scheidt, A.; Ignatius, A.
Hypochlorhydria-induced calcium malabsorption does not affect fracture healing but increases post-traumatic bone loss in the intact skeleton
J Orthop Res, 34 (11) :1914-1921
2016
DOI:10.1002/jor.23221
File:http://www.ncbi.nlm.nih.gov/pubmed/26945509
726.
Belavy, D. L.; Adams, M.; Brisby, H.; Cagnie, B.; Danneels, L.; Fairbank, J.; Hargens, A. R.; Judex, S.; Scheuring, R. A.; Sovelius, R.; Urban, J.; Dieen, J. H.; Wilke, H. J.
Disc herniations in astronauts: What causes them, and what does it tell us about herniation on earth?
Eur Spine J, 25 (1) :144-154
2016
DOI:10.1007/s00586-015-3917-y
File:http://www.ncbi.nlm.nih.gov/pubmed/25893331
725.
Ray, S.; Thormann, U.; Sommer, U.; Khassawna, T. E.; Hundgeburth, M.; Henss, A.; Rohnke, M.; Lips, K. S.; Heiss, C.; Heinemann, S.; Hanke, T.; Dürselen, L.; Schnettler, R.; Alt, V.
Effects of macroporous, strontium loaded xerogel-scaffolds on new bone formation in critical-size metaphyseal fracture defects in ovariectomized rats
Injury, 47 Suppl 1 :S52-61
2016
DOI:10.1016/S0020-1383(16)30013-4
File:http://www.ncbi.nlm.nih.gov/pubmed/26768293
724.
Riegger, J.; Joos, H.; Palm, H. G.; Friemert, B.; Reichel, H.; Ignatius, A.; Brenner, R. E.
Antioxidative therapy in an ex vivo human cartilage trauma-model: Attenuation of trauma-induced cell loss and ECM-destructive enzymes by N-acetyl cysteine
Osteoarthritis Cartilage, 24 (12) :2171-2180
2016
DOI:10.1016/j.joca.2016.07.019
File:http://www.ncbi.nlm.nih.gov/pubmed/27514995
723.
Müller, S. A.; Dürselen, L.; Heisterbach, P.; Evans, C.; Majewski, M.
Effect of a Simple Collagen Type I Sponge for Achilles Tendon Repair in a Rat Model
Am J Sports Med, 44 (8) :1998-2004
2016
DOI:10.1177/0363546516641942
File:http://www.ncbi.nlm.nih.gov/pubmed/27159286
722.
Wilke, H. J.; Kienle, A.; Maile, S.; Rasche, V.; Berger-Roscher, N.
A new dynamic six degrees of freedom disc-loading simulator allows to provoke disc damage and herniation
Eur Spine J, 25 (5) :1363-72
2016
DOI:10.1007/s00586-016-4416-5
File:http://www.ncbi.nlm.nih.gov/pubmed/26838335
721.
Haffner-Luntzer, M.; Heilmann, A.; Rapp, A. E.; Roessler, R.; Schinke, T.; Amling, M.; Ignatius, A.; Liedert, A.
Antagonizing Midkine Accelerates Fracture Healing in Mice by Enhanced Bone Formation in the Fracture Callus
Br J Pharmacol, 173 (14) :2237-49
2016
DOI:10.1111/bph.13503
File:http://www.ncbi.nlm.nih.gov/pubmed/27111560
720.
Teixeira, G. Q.; Leite Pereira, C.; Castro, F.; Ferreira, J. R.; Gomez-Lazaro, M.; Aguiar, P.; Barbosa, M. A.; Neidlinger-Wilke, C.; Goncalves, R. M.
Anti-inflammatory Chitosan/Poly-gamma-glutamic acid nanoparticles control inflammation while remodeling extracellular matrix in degenerated intervertebral disc
Acta Biomater, 42 :168-179
2016
DOI:10.1016/j.actbio.2016.06.013
File:http://www.ncbi.nlm.nih.gov/pubmed/27321188
719.
Wilke, H. J.; Kaiser, D.; Volkheimer, D.; Hackenbroch, C.; Puschel, K.; Rauschmann, M.
A pedicle screw system and a lamina hook system provide similar primary and long-term stability: a biomechanical in vitro study with quasi-static and dynamic loading conditions
Eur Spine J, 25 (9) :2919-2928
2016
DOI:10.1007/s00586-016-4679-x
File:http://www.ncbi.nlm.nih.gov/pubmed/27405823
718.
Ehrnthaller, C.; Huber-Lang, M.; Kovtun, A.; Rapp, A. E.; Kemmler, J.; Gebhard, F.; Ignatius, A.
C5aR inhibition in the early inflammatory phase does not affect bone regeneration in a model of uneventful fracture healing
Eur J Med Res, 21 (1) :42
2016
DOI:10.1186/s40001-016-0236-7
File:https://www.ncbi.nlm.nih.gov/pubmed/27784330
717.
Pratsinis, H.; Papadopoulou, A.; Neidlinger-Wilke, C.; Brayda-Bruno, M.; Wilke, H. J.; Kletsas, D.
Cyclic tensile stress of human annulus fibrosus cells induces MAPK activation: involvement in proinflammatory gene expression
Osteoarthritis Cartilage, 24 (4) :679-87
2016
DOI:10.1016/j.joca.2015.11.022
File:http://www.ncbi.nlm.nih.gov/pubmed/26687822
716.
Simon, M. J.; Beil, F. T.; Riedel, C.; Lau, G.; Tomsia, A.; Zimmermann, E. A.; Koehne, T.; Ueblacker, P.; Ruther, W.; Pogoda, P.; Ignatius, A.; Amling, M.; Oheim, R.
Deterioration of teeth and alveolar bone loss due to chronic environmental high-level fluoride and low calcium exposure
Clin Oral Investig, 20 (9) :2361-2370
2016
DOI:10.1007/s00784-016-1727-1
File:http://www.ncbi.nlm.nih.gov/pubmed/26818581
715.
Kienle, A.; Graf, N.; Wilke, H. J.
Does impaction of titanium-coated interbody fusion cages into the disc space cause wear debris and/or delamination?
Spine J, 16 :2
2016
DOI:10.1016/j.spinee.2015.09.038
File:http://www.ncbi.nlm.nih.gov/pubmed/26409208
714.
Teixeira, G. Q.; Boldt, A.; Nagl, I.; Pereira, C. L.; Benz, K.; Wilke, H. J.; Ignatius, A.; Barbosa, M. A.; Goncalves, R. M.; Neidlinger-Wilke, C.
A Degenerative/Proinflammatory Intervertebral Disc Organ Culture: An Ex Vivo Model for Anti-inflammatory Drug and Cell Therapy
Tissue Eng Part C Methods, 22 (1) :8-19
2016
DOI:10.1089/ten.tec.2015.0195
File:http://www.ncbi.nlm.nih.gov/pubmed/26565141

2015

713.
Qin, R.; Schmid, H.; Muenzberg, C.; Maass, U.; Krndija, D.; Adler, G.; Seufferlein, T.; Liedert, A.; Ignatius, A.; Oswald, F.; Eiseler, T.; Wichert, G.
Phosphorylation and turnover of paxillin in focal contacts is controlled by force and defines the dynamic state of the adhesion site
Cytoskeleton (Hoboken), 72 (2) :101-112
2015
DOI:10.1002/cm.21209
File:http://www.ncbi.nlm.nih.gov/pubmed/25620625
712.
Berger-Roscher, N.; Galbusera, F.; Rasche, V.; Wilke, H. J.
Intervertebral disc lesions: visualisation with ultra-high field MRI at 11.7 T
Eur Spine J, 24 (11) :2488-2495
2015
DOI:10.1007/s00586-015-4146-0
File:http://www.ncbi.nlm.nih.gov/pubmed/26206293
711.
Volkheimer, D.; Malakoutian, M.; Oxland, T. R.; Wilke, H. J.
Limitations of current in vitro test protocols for investigation of instrumented adjacent segment biomechanics: critical analysis of the literature
Eur Spine J, 24 (9) :1882-1892
2015
DOI:10.1007/s00586-015-4040-9
File:http://www.ncbi.nlm.nih.gov/pubmed/26038156
710.
Freutel, M.; Galbusera, F.; Ignatius, A.; Dürselen, L.
Material properties of individual menisci and their attachments obtained through inverse FE-analysis
J Biomech, 48 (8) :1343-1349
2015
DOI:10.1016/j.jbiomech.2015.03.014
File:http://www.ncbi.nlm.nih.gov/pubmed/25843259
709.
Freutel, M.; Scholz, N. B.; Seitz, A. M.; Ignatius, A.; Dürselen, L.
Mechanical properties and morphological analysis of the transitional zone between meniscal body and ligamentous meniscal attachments
J Biomech, 48 (8) :1350-1355
2015
DOI:10.1016/j.jbiomech.2015.03.003
File:http://www.ncbi.nlm.nih.gov/pubmed/25841294
708.
Popov, C.; Burggraf, M.; Kreja, L.; Ignatius, A.; Schieker, M.; Docheva, D.
Mechanical stimulation of human tendon stem/progenitor cells results in upregulation of matrix proteins, integrins and MMPs, and activation of p38 and ERK1/2 kinases
BMC Mol Biol, 16 (1) :6
2015
DOI:10.1186/s12867-015-0036-6
File:http://www.ncbi.nlm.nih.gov/pubmed/25880261
707.
Malandrino, A.; Pozo, J. M.; Castro-Mateos, I.; Frangi, A. F.; Rijsbergen, M. M.; Ito, K.; Wilke, H. J.; Dao, T. T.; Ho Ba Tho, M. C.; Noailly, J.
On the relative relevance of subject-specific geometries and degeneration-specific mechanical properties for the study of cell death in human intervertebral disk models
Front Bioeng Biotechnol, 3 :5
2015
DOI:10.3389/fbioe.2015.00005
File:http://www.ncbi.nlm.nih.gov/pubmed/25717471
706.
Galbusera, F.; Volkheimer, D.; Reitmaier, S.; Berger-Roscher, N.; Kienle, A.; Wilke, H. J.
Pedicle screw loosening: a clinically relevant complication?
Eur Spine J, 24 (5) :1005-16
2015
DOI:10.1007/s00586-015-3768-6
File:http://www.ncbi.nlm.nih.gov/pubmed/25616349
705.
Schmidt, H.; Häussler, K.; Wilke, H. J.; Wolfram, U.
Structural behavior of human lumbar intervertebral disc under direct shear
J Appl Biomater Funct Mater, 13 (1) :e66-e71
2015
DOI:10.5301/jabfm.5000176
File:http://www.ncbi.nlm.nih.gov/pubmed/24744233
704.
Galbusera, F.; Bassani, T.; La Barbera, L.; Ottardi, C.; Schlager, B.; Brayda-Bruno, M.; Villa, T.; Wilke, H. J.
Planning the Surgical Correction of Spinal Deformities: Toward the Identification of the Biomechanical Principles by Means of Numerical Simulation
Front Bioeng Biotechnol, 3 :178
2015
DOI:10.3389/fbioe.2015.00178
File:http://www.ncbi.nlm.nih.gov/pubmed/26579518
703.
Schwarz, S.; Elsaesser, A. F.; Koerber, L.; Goldberg-Bockhorn, E.; Seitz, A. M.; Bermueller, C.; Dürselen, L.; Ignatius, A.; Breiter, R.; Rotter, N.
Processed xenogenic cartilage as innovative biomatrix for cartilage tissue engineering: effects on chondrocyte differentiation and function
J Tissue Eng Regen Med, 9 (12) :E239-E251
2015
DOI:10.1002/term.1650
File:http://www.ncbi.nlm.nih.gov/pubmed/23193064 http://onlinelibrary.wiley.com/doi/10.1002/term.1650/abstract
702.
Huber-Lang, M.; Ignatius, A.; Brenner, R. E.
Role of Complement on Broken Surfaces After Trauma
Adv Exp Med Biol, 865 :43-55
2015
DOI:10.1007/978-3-319-18603-0_3
File:http://www.ncbi.nlm.nih.gov/pubmed/26306442
701.
Lips, K. S.; Yanko, O.; Kneffel, M.; Panzer, I.; Kauschke, V.; Madzharova, M.; Henss, A.; Schmitz, P.; Rohnke, M.; Bauerle, T.; Liu, Y.; Kampschulte, M.; Langheinrich, A. C.; Dürselen, L.; Ignatius, A.; Heiss, C.; Schnettler, R.; Kilian, O.
Small changes in bone structure of female inverted question mark7 nicotinic acetylcholine receptor knockout mice
BMC Musculoskelet Disord, 16 (1) :5
2015
DOI:10.1186/s12891-015-0459-8
File:http://www.ncbi.nlm.nih.gov/pubmed/25636336
700.
Rapp, A. E.; Bindl, R.; Heilmann, A.; Erbacher, A.; Muller, I.; Brenner, R. E.; Ignatius, A.
Systemic mesenchymal stem cell administration enhances bone formation in fracture repair but not load-induced bone formation
Eur Cell Mater, 29 :22-34
2015
File:http://www.ncbi.nlm.nih.gov/pubmed/25552426
699.
Wehrle, E.; Liedert, A.; Heilmann, A.; Wehner, T.; Bindl, R.; Fischer, L.; Haffner-Luntzer, M.; Jakob, F.; Schinke, T.; Amling, M.; Ignatius, A.
The impact of low-magnitude high-frequency vibration on fracture healing is profoundly influenced by the oestrogen status
Dis Model Mech, 8 (1) :93-104
2015
DOI:10.1242/dmm.018622
File:http://www.ncbi.nlm.nih.gov/pubmed/25381012
698.
Ehrnthaller, C.; Flierl, M.; Perl, M.; Denk, S.; Unnewehr, H.; Ward, P. A.; Radermacher, P.; Ignatius, A.; Gebhard, F.; Chinnaiyan, A.; Huber-Lang, M.
The molecular fingerprint of lung inflammation after blunt chest trauma
Eur J Med Res, 20 (1) :70
2015
DOI:10.1186/s40001-015-0164-y
File:http://www.ncbi.nlm.nih.gov/pubmed/26303896
697.
Kovtun, A.; Göckelmann, M. J.; Niclas, A. A.; Montufar, E. B.; Ginebra, M. P.; Planell, J. A.; Santin, M.; Ignatius, A.
In vivo performance of novel soybean/gelatin-based bioactive and injectable hydroxyapatite foams
Acta Biomater, 12 :242-9
2015
DOI:10.1016/j.actbio.2014.10.034
File:http://www.ncbi.nlm.nih.gov/pubmed/25448348
696.
Freutel, M.; Seitz, A. M.; Ignatius, A.; Dürselen, L.
Influence of partial meniscectomy on attachment forces, superficial strain and contact mechanics in porcine knee joints
Knee Surg Sports Traumatol Arthrosc, 23 (1) :74-82
2015
DOI:10.1007/s00167-014-2951-3
File:http://www.ncbi.nlm.nih.gov/pubmed/24671386
695.
Wagner, K.; Gröger, M.; McCook, O.; Scheuerle, A.; Asfar, P.; Stahl, B.; Huber-Lang, M.; Ignatius, A.; Jung, B.; Duechs, M.; Möller, P.; Georgieff, M.; Calzia, E.; Radermacher, P.; Wagner, F.
Blunt Chest Trauma in Mice after Cigarette Smoke-Exposure: Effects of Mechanical Ventilation with 100 % O2
PLoS One, 10 (7) :e0132810
2015
DOI:10.1371/journal.pone.0132810
File:http://www.ncbi.nlm.nih.gov/pubmed/26225825
694.
Gruchenberg, K.; Ignatius, A.; Friemert, B.; Lübken, F.; Skaer, N.; Gellynck, K.; Kessler, O.; Dürselen, L.
In vivo performance of a novel silk fibroin scaffold for partial meniscal replacement in a sheep model
Knee Surg Sports Traumatol Arthrosc, 23 (8) :2218-29
2015
DOI:10.1007/s00167-014-3009-2
File:http://www.ncbi.nlm.nih.gov/pubmed/24770350
693.
Kauschke, V.; Kneffel, M.; Floel, W.; Hartmann, S.; Kampschulte, M.; Dürselen, L.; Ignatius, A.; Schnettler, R.; Heiss, C.; Lips, K. S.
Bone status of acetylcholinesterase-knockout mice
Int Immunopharmacol, 29 (1) :222-230
2015
DOI:10.1016/j.intimp.2015.07.046
File:http://www.ncbi.nlm.nih.gov/pubmed/26250336 http://ac.els-cdn.com/S1567576915300588/1-s2.0-S1567576915300588-main.pdf?_tid=2424816a-7e20-11e5-bb0c-00000aab0f01&acdnat=1446111401_5020b4d28afab4cd2bdd0bdeed30384d http://ac.els-cdn.com/S1567576915300588/1-
692.
El Khassawna, T.; Böcker, W.; Brodsky, K.; Weisweiler, D.; Govindarajan, P.; Kampschulte, M.; Thormann, U.; Henss, A.; Rohnke, M.; Bauer, N.; Müller, R.; Deutsch, A.; Ignatius, A.; Dürselen, L.; Langheinrich, A.; Lips, K. S.; Schnettler, R.; Heiss, C.
Impaired extracellular matrix structure resulting from malnutrition in ovariectomized mature rats
Histochem Cell Biol, 144 (5) :491-507
2015
DOI:10.1007/s00418-015-1356-9
File:http://www.ncbi.nlm.nih.gov/pubmed/26210855
691.
Wilke, H. J.
[Biomechanical aspects of vertebral augmentation]
Unfallchirurg, 118 (10) :822-830
2015
DOI:10.1007/s00113-015-0066-z
File:http://www.ncbi.nlm.nih.gov/pubmed/26358323
689.
Haffner-Luntzer, M.; Liedert, A.; Ignatius, A.
[Mechanobiology and bone metabolism : Clinical relevance for fracture treatment]
Unfallchirurg, 118 (12) :1000-6
2015
DOI:10.1007/s00113-015-0102-z
File:http://www.ncbi.nlm.nih.gov/pubmed/26577661
688.
Rapp, A. E.; Kroner, J.; Baur, S.; Schmid, F.; Walmsley, A.; Mottl, H.; Ignatius, A.
Analgesia via blockade of NGF/TrkA signaling does not influence fracture healing in mice
J Orthop Res, 33 (8) :1235-1241
2015
DOI:10.1002/jor.22892
File:http://www.ncbi.nlm.nih.gov/pubmed/25876530
687.
Dürselen, L; Freutel, M.
Biomechanik des Meniskus
Orthopädie und Unfallchirurgie up2date, 10 (3) :215-227
2015
686.
Sörensen, JH; Dürselen, L; Welch, K; Sörensen, TC; Procter, P; Engqvist, H; Stromme, M; Ignatius, A; Steckel, H
Biomimetic Hydroxyapatite Coated Titanium Screws Demonstrate Rapid Implant Stabilization and Safe Removal In-Vivo
J Biomater Nanobiotechnol, 6 (1) :20-35
2015
DOI:http://dx.doi.org/10.4236/jbnb.2015.61003
685.
Lips, K. S.; Kneffel, M.; Willscheid, F.; Mathies, F. M.; Kampschulte, M.; Hartmann, S.; Panzer, I.; Dürselen, L.; Heiss, C.; Kauschke, V.
Altered ultrastructure, density and cathepsin K expression in bone of female muscarinic acetylcholine receptor M3 knockout mice
Int Immunopharmacol, 29 (1) :201-207
2015
DOI:10.1016/j.intimp.2015.05.012
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684.
Haupt, M.; Kauschke, V.; Sender, J.; Kampschulte, M.; Kovtun, A.; Dürselen, L.; Heiss, C.; Lips, K. S.
Bone status of adult female butyrylcholinesterase gene-deficient mice
Int Immunopharmacol, 29 (1) :208-214
2015
DOI:10.1016/j.intimp.2015.06.029
File:http://www.ncbi.nlm.nih.gov/pubmed/26138460 http://ac.els-cdn.com/S1567576915300059/1-s2.0-S1567576915300059-main.pdf?_tid=14a56452-7e20-11e5-a71f-00000aab0f26&acdnat=1446111375_6a2191e6c0577147b54c8f5410db6527 http://ac.els-cdn.com/S1567576915300059/1-
683.
Steiner, M.; Volkheimer, D.; Meyers, N.; Wehner, T.; Wilke, H. J.; Claes, L.; Ignatius, A.
Comparison between Different Methods for Biomechanical Assessment of Ex Vivo Fracture Callus Stiffness in Small Animal Bone Healing Studies
PLoS One, 10 (3) :e0119603
2015
DOI:10.1371/journal.pone.0119603
File:http://www.ncbi.nlm.nih.gov/pubmed/25781027
682.
Doyle, H.; Lohfeld, S.; Dürselen, L.; McHugh, P.
Computational modelling of ovine critical-sized tibial defects with implanted scaffolds and prediction of the safety of fixator removal
J Mech Behav Biomed Mater, 44C :133-146
2015
DOI:10.1016/j.jmbbm.2015.01.008
File:http://www.ncbi.nlm.nih.gov/pubmed/25637824
681.
Wilke, H. J.; Mathes, B.; Midderhoff, S.; Graf, N.
Development of a scoliotic spine model for biomechanical in vitro studies
Clin Biomech (Bristol, Avon), 30 (2) :182-187
2015
DOI:10.1016/j.clinbiomech.2014.12.002
File:http://www.ncbi.nlm.nih.gov/pubmed/25533272
680.
Joos, H.; Leucht, F.; Riegger, J.; Hogrefe, C.; Fiedler, J.; Dürselen, L.; Reichel, H.; Ignatius, A.; Brenner, R. E.
Differential Interactive Effects of Cartilage Traumatization and Blood Exposure In Vitro and In Vivo
Am J Sports Med, 43 (11) :2822-32
2015
DOI:10.1177/0363546515602248
File:http://www.ncbi.nlm.nih.gov/pubmed/26362437 http://ajs.sagepub.com/content/early/2015/09/11/0363546515602248.long
679.
Malakoutian, M.; Volkheimer, D.; Street, J.; Dvorak, M. F.; Wilke, H. J.; Oxland, T. R.
Do in vivo kinematic studies provide insight into adjacent segment degeneration? A qualitative systematic literature review
Eur Spine J, 24 (9) :1865-1881
2015
DOI:10.1007/s00586-015-3992-0
File:http://www.ncbi.nlm.nih.gov/pubmed/26055273
678.
Waschke, A.; Berger-Roscher, N.; Kielstein, H.; Ewald, C.; Kalff, R.; Wilke, H. J.
Cement Augmented Anterior Odontoid Screw Fixation is Biomechanically Advantageous in Osteoporotic Patients with Anderson Type II Fractures
J Spinal Disord Tech, 28 (3) :E126-32
2015
DOI:10.1097/BSD.0000000000000177
File:http://www.ncbi.nlm.nih.gov/pubmed/25310397

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