Publications

You find here a complete list of publications authored or coauthered by members of our institute since 1974. By default the entire list is presented.

2015

677.
Kemmler, J.; Bindl, R.; McCook, O.; Wagner, F.; Gröger, M.; Wagner, K.; Scheuerle, A.; Radermacher, P.; Ignatius, A.
Exposure to 100% Oxygen Abolishes the Impairment of Fracture Healing after Thoracic Trauma
PLoS One, 10 (7) :e0131194
2015
DOI:10.1371/journal.pone.0131194
File:http://www.ncbi.nlm.nih.gov/pubmed/26147725

2014

676.
Neidlinger-Wilke, C.; Galbusera, F.; Pratsinis, H.; Mavrogonatou, E.; Mietsch, A.; Kletsas, D.; Wilke, H. J.
Mechanical loading of the intervertebral disc: from the macroscopic to the cellular level
Eur Spine J, 23 (Suppl 3) :S333-S343
2014
DOI:10.1007/s00586-013-2855-9
File:http://www.ncbi.nlm.nih.gov/pubmed/23793454
675.
Neidlinger-Wilke, C.; Boldt, A.; Brochhausen, C.; Galbusera, F.; Carstens, C.; Copf, F.; Schultheiß, M.; Lazary, A.; Brayda-Bruno, M.; Ignatius, A.; Wilke, H. J.
Molecular Interactions Between Human Cartilaginous Endplates and Nucleus Pulposus Cells: A Preliminary Investigation
Spine (Phila Pa 1976), 39 (17) :1355-1364
2014
DOI:10.1097/BRS.0000000000000372
File:http://www.ncbi.nlm.nih.gov/pubmed/24831500
674.
Haffner-Luntzer, M.; Heilmann, A.; Rapp, A.; Beie, S.; Schinke, T.; Amling, M.; Ignatius, A; Liedert, A.
Midkine Deficiency Delays Chondrogenesis during the Early Phase of Fracture Healing in Mice
PLoS One, 9 (12) :e116282
2014
File:pdfhttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC4281158/pdf/pone.0116282.pdf
673.
Freutel, M.; Seitz, A. M.; Galbusera, F.; Bornstedt, A.; Rasche, V.; Knothe Tate, M. L.; Ignatius, A.; Dürselen, L.
Medial meniscal displacement and strain in three dimensions under compressive loads: MR assessment
J Magn Reson Imaging, 40 :1181-1188
2014
DOI:10.1002/jmri.24461
File:http://www.ncbi.nlm.nih.gov/pubmed/24323799
672.
Galbusera, F.; Brayda-Bruno, M.; Wilke, H. J.
Is post-contrast MRI a valuable method for the study of the nutrition of the intervertebral disc?
J Biomech, 47 (12) :3028-34
2014
DOI:10.1016/j.jbiomech.2014.06.039
File:http://www.ncbi.nlm.nih.gov/pubmed/25059896
671.
Galbusera, F.; Freutel, M.; Dürselen, L.; D'Aiuto, M.; Croce, D.; Villa, T.; Sansone, V.; Innocenti, B.
Material Models and Properties in the Finite Element Analysis of Knee Ligaments: A Literature Review
Front Bioeng Biotechnol, 2 :54
2014
DOI:10.3389/fbioe.2014.00054
File:http://www.ncbi.nlm.nih.gov/pubmed/25478560
670.
Oheim, R.; Beil, F. T.; Krause, M.; Bindl, R.; Ignatius, A.; Pogoda, P.
Mandibular bone loss in ewe induced by hypothalamic-pituitary disconnection
Clin Oral Implants Res, 25 (11) :1239-44
2014
DOI:10.1111/clr.12259
File:http://www.ncbi.nlm.nih.gov/pubmed/24102843
669.
Matzaroglou, C.; Georgiou, C. S.; Panagopoulos, A.; Assimakopoulos, K.; Wilke, H. J.; Habermann, B.; Panos, G.; Kafchitsas, K.
Kummell's Disease: Clarifying the Mechanisms and Patients' Inclusion Criteria
Open Orthop J, 8 :288-97
2014
DOI:10.2174/1874325001408010288
File:http://www.ncbi.nlm.nih.gov/pubmed/25246995
668.
Galbusera, F.; Tibiletti, M.; Brayda-Bruno, M.; Neidlinger-Wilke, C.; Wilke, H. J.
Inverse numerical prediction of the transport properties of vertebral endplates in low back pain patients
Biomed Tech (Berl), 59 (5) :385–397
2014
DOI:10.1515/bmt-2013-0122
File:http://www.ncbi.nlm.nih.gov/pubmed/24633746
667.
Steiner, M.; Claes, L.; Ignatius, A.; Simon, U.; Wehner, T.
Numerical Simulation of Callus Healing for Optimization of Fracture Fixation Stiffness
PLoS One, 9 (7) :e101370
2014
DOI:10.1371/journal.pone.0101370
File:http://www.ncbi.nlm.nih.gov/pubmed/24991809
666.
Galbusera, F.; Brayda-Bruno, M.; Costa, F.; Wilke, H. J.
Numerical evaluation of the correlation between the normal variation in the sagittal alignment of the lumbar spine and the spinal loads
J Orthop Res, 32 (4) :537-544
2014
DOI:10.1002/jor.22569
File:http://www.ncbi.nlm.nih.gov/pubmed/24375659
665.
Qi, Y.; Jiang, D.; Sindrilaru, A.; Stegemann, A.; Schatz, S.; Treiber, N.; Rojewski, M.; Schrezenmeier, H.; Beken, S. V.; Wlaschek, M.; Bohm, M.; Seitz, A.; Scholz, N.; Dürselen, L.; Brinckmann, J.; Ignatius, A.; Scharffetter-Kochanek, K.
TSG-6 Released from Intradermally Injected Mesenchymal Stem Cells Accelerates Wound Healing and Reduces Tissue Fibrosis in Murine Full-Thickness Skin Wounds
J Invest Dermatol, 134 (2) :526-537
2014
DOI:10.1038/jid.2013.328
File:http://www.ncbi.nlm.nih.gov/pubmed/23921952
664.
Leyh, M.; Seitz, A.; Dürselen, L.; Springorum, H. R.; Angele, P.; Ignatius, A.; Grifka, J.; Grässel, S.
Osteoarthritic cartilage explants affect extracellular matrix production and composition in cocultured bone marrow-derived mesenchymal stem cells and articular chondrocytes
Stem Cell Res Ther, 5 (3) :77
2014
DOI:10.1186/scrt466
File:http://www.ncbi.nlm.nih.gov/pubmed/24916039
663.
Liedert, A.; Röntgen, V.; Schinke, T.; Benisch, P.; Ebert, R.; Jakob, F.; Klein-Hitpass, L.; Lennerz, J. K.; Amling, M.; Ignatius, A.
Osteoblast-Specific Krm2 Overexpression and Lrp5 Deficiency Have Different Effects on Fracture Healing in Mice
PLoS One, 9 (7) :e103250
2014
DOI:10.1371/journal.pone.0103250
File:http://www.ncbi.nlm.nih.gov/pubmed/25061805
662.
Werz, T.; Baumann, M.; Wolfram, U.; Krill, C. E.
Particle tracking during Ostwald ripening using time-resolved laboratory X-ray microtomography
Materials Characterization, 90 :185-195
2014
DOI:10.1016/j.matchar.2014.01.022
File:
661.
Wehner, T.; Steiner, M.; Ignatius, A.; Claes, L.
Prediction of the time course of callus stiffness as a function of mechanical parameters in experimental rat fracture healing studies - a numerical study
PLoS One, 9 (12) :e115695
2014
DOI:10.1371/journal.pone.0115695
File:http://www.ncbi.nlm.nih.gov/pubmed/25532060

2014

660.
Böcker, W.; El Khassawna, T.; Bauer, N.; Brodsky, K.; Weisweiler, D.; Govindarajan, P.; Schlewitz, G.; Kampschulte, M.; Dürselen, L.; Thormann, U.; Szalay, G.; Schnettler, R.; Langheinrich, A. C.; Heiss, C.
Short-term glucocorticoid treatment causes spinal osteoporosis in ovariectomized rats
Eur Spine J, 23 (11) :2437-2448
2014
DOI:10.1007/s00586-014-3463-z
File:http://www.ncbi.nlm.nih.gov/pubmed/25077942
659.
Leyh, M.; Seitz, A.; Dürselen, L.; Schaumburger, J.; Ignatius, A.; Grifka, J.; Grässel, S.
Subchondral bone influences chondrogenic differentiation and collagen production of human bone marrow-derived mesenchymal stem cells and articular chondrocytes
Arthritis Res Ther, 16 (5) :453
2014
DOI:10.1186/s13075-014-0453-9
File:http://www.ncbi.nlm.nih.gov/pubmed/25296561
658.
Wehner, T.; Gruchenberg, K.; Bindl, R.; Recknagel, S.; Steiner, M.; Ignatius, A.; Claes, L.
Temporal delimitation of the healing phases via monitoring of fracture callus stiffness in rats
J Orthop Res, 32 (12) :1589–1595
2014
DOI:10.1002/jor.22721
File:http://www.ncbi.nlm.nih.gov/pubmed/25183200
657.
Nelitz, M.; Wehner, T.; Steiner, M.; Dürselen, L.; Lippacher, S.
The effects of femoral external derotational osteotomy on frontal plane alignment
Knee Surg Sports Traumatol Arthrosc, 22 (11) :2740-2746
2014
DOI:10.1007/s00167-013-2618-5
File:http://www.ncbi.nlm.nih.gov/pubmed/23887859
656.
Liedert, A.; Schinke, T.; Ignatius, A.; Amling, M.
The Role of Midkine in Skeletal Remodeling
Br J Pharmacol, 171 (4) :870-8
2014
DOI:10.1111/bph.12412
File:http://www.ncbi.nlm.nih.gov/pubmed/24102259
655.
Claes, L.
Ultraschall als Therapieansatz zur Beschleunigung der Frakturheilung
Orthopädie und Unfallchirurgie up2date, 9 (5) :427-436
2014
654.
Schwen, L. O.; Wolfram, U.
Validation of composite finite elements efficiently simulating elasticity of trabecular bone
Comput Methods Biomech Biomed Engin, 17 (6) :652-60
2014
DOI:10.1080/10255842.2012.714373
File:http://www.ncbi.nlm.nih.gov/pubmed/23025631
653.
Reitmaier, S.; Kreja, L.; Gruchenberg, K.; Kanter, B.; Silva-Correia, J.; Oliveira, J. M.; Reis, R. L.; Perugini, V.; Santin, M.; Ignatius, A.; Wilke, H. J.
In vivo biofunctional evaluation of hydrogels for disc regeneration
Eur Spine J, 23 (1) :19-26
2014
DOI:10.1007/s00586-013-2998-8
File:http://www.ncbi.nlm.nih.gov/pubmed/24121748
652.
Reitmaier, S.; Volkheimer, D.; Berger-Roscher, N.; Wilke, H. J.; Ignatius, A.
Increase or decrease in stability after nucleotomy? Conflicting in vitro and in vivo results in the sheep model
J R Soc Interface, 11 (100)
2014
DOI:10.1098/rsif.2014.0650
File:http://www.ncbi.nlm.nih.gov/pubmed/25209401
651.
McCook, O.; Radermacher, P.; Volani, C.; Asfar, P.; Ignatius, A.; Kemmler, J.; Möller, P.; Szabó, C.; Whiteman, M.; Wood, M. E.; Wang, R.; Georgieff, M.; Wachter, U.
H2S during circulatory shock: Some unresolved questions
Nitric Oxide, 41 :48-61
2014
DOI:10.1016/j.niox.2014.03.163
File:http://www.ncbi.nlm.nih.gov/pubmed/24650697
650.
Ewert, Katrin; Wilke, H. J.
In der Bandscheibenwerkstatt
Focus Gesundheit, Der Rücken, 21 :80-85
2014
649.
Galbusera, F.; Bashkuev, M.; Wilke, H. J.; Shirazi-Adl, A.; Schmidt, H.
Comparison of various contact algorithms for poroelastic tissues
Comput Methods Biomech Biomed Engin, 17 (12) :1323-34
2014
DOI:10.1080/10255842.2012.745858
File:http://www.ncbi.nlm.nih.gov/pubmed/23244496
648.
Wölfle, J. V.; Fiedler, J.; Dürselen, L.; Reichert, J.; Scharnweber, D.; Forster, A.; Schwenzer, B.; Reichel, H.; Ignatius, A.; Brenner, R. E.
Improved Anchorage of Ti6Al4V Orthopaedic Bone Implants through Oligonucleotide Mediated Immobilization of BMP-2 in Osteoporotic Rats
PLoS One, 9 (1) :e86151
2014
DOI:10.1371/journal.pone.0086151
File:http://www.ncbi.nlm.nih.gov/pubmed/24465929
647.
Claes, L.; Reusch, M.; Wehner, T.; Dürselen, L.; Ignatius, A.
Adaptation of trabecular bone to very high mechanical loads
Osteologie, 23 (3) :202-206
2014
646.
Brayda-Bruno, M.; Tibiletti, M.; Ito, K.; Fairbank, J.; Galbusera, F.; Zerbi, A.; Roberts, S.; Wachtel, E.; Merkher, Y.; Sivan, S. S.
Advances in the diagnosis of degenerated lumbar discs and their possible clinical application
Eur Spine J, 23 (Suppl 3) :S315-S323
2014
DOI:10.1007/s00586-013-2960-9
File:http://www.ncbi.nlm.nih.gov/pubmed/23978994
645.
Galbusera, F.; Rijsbergen, M.; Ito, K.; Huyghe, J. M.; Brayda-Bruno, M.; Wilke, H. J.
Ageing and degenerative changes of the intervertebral disc and their impact on spinal flexibility
Eur Spine J, 23 (Suppl 3) :S324-S332
2014
DOI:10.1007/s00586-014-3203-4
File:http://www.ncbi.nlm.nih.gov/pubmed/24482074
644.
Govindarajan, P.; Böcker, W.; El Khassawna, T.; Kampschulte, M.; Schlewitz, G.; Huerter, B.; Sommer, U.; Dürselen, L.; Ignatius, A.; Bauer, N. B.; Szalay, G.; Wenisch, S.; Lips, K. S.; Schnettler, R.; Langheinrich, A. C.; Heiss, C.
Bone Matrix, Cellularity, and Structural Changes in a Rat Model with High-Turnover Osteoporosis Induced by Combined Ovariectomy and a Multiple-Deficient Diet
Am J Pathol, 184 (3) :765-777
2014
DOI:10.1016/j.ajpath.2013.11.011
File:http://www.ncbi.nlm.nih.gov/pubmed/24384131
643.
Müller, A.; Schleid, T.; Doser, M.; Müschenborn, N.; Tautzenberger, A.; Ignatius, A; Clauß, B.; Buchmeiser, M.R.
Calcium Cl/OH-Apatite, Cl/OH-Apatite/Al2O3 and Ca3(PO4)2 Fibre Nonwovens: Potential Ceramic Components for Osteosynthesis
J Eur Ceram Soc, 34 (15) :3993-4000
2014
642.
Kregar Velikonja, N.; Urban, J.; Frohlich, M.; Neidlinger-Wilke, C.; Kletsas, D.; Potocar, U.; Turner, S.; Roberts, S.
Cell sources for nucleus pulposus regeneration
Eur Spine J, 23 (Suppl 3) :S364-S374
2014
DOI:10.1007/s00586-013-3106-9
File:http://www.ncbi.nlm.nih.gov/pubmed/24297331
641.
Käfer, W.; Cakir, B.; Midderhoff, S.; Reichel, H.; Wilke, H. J.
Circumferential dynamic stabilization of the lumbar spine: a biomechanical analysis
Eur Spine J, 23 (11) :2330-2339
2014
DOI:10.1007/s00586-014-3286-y
File:http://www.ncbi.nlm.nih.gov/pubmed/24722881
640.
Villa, T.; La Barbera, L.; Galbusera, F.
Comparative analysis of international standards for the fatigue testing of posterior spinal fixation systems
Spine J, 14 (4) :695-704
2014
DOI:10.1016/j.spinee.2013.08.032
File:http://www.ncbi.nlm.nih.gov/pubmed/24268390
639.
Dreischarf, M.; Zander, T.; Shirazi-Adl, A.; Puttlitz, C. M.; Adam, C. J.; Chen, C. S.; Goel, V. K.; Kiapour, A.; Kim, Y. H.; Labus, K. M.; Little, J. P.; Park, W. M.; Wang, Y. H.; Wilke, H. J.; Rohlmann, A.; Schmidt, H.
Comparison of eight published static finite element models of the intact lumbar spine: Predictive power of models improves when combined together
J Biomech, 47 (8) :1757-66
2014
DOI:10.1016/j.jbiomech.2014.04.002
File:http://www.ncbi.nlm.nih.gov/pubmed/24767702
638.
La Barbera, L.; Galbusera, F.; Villa, T.; Costa, F.; Wilke, H. J.
ASTM F1717 standard for the preclinical evaluation of posterior spinal fixators: Can we improve it?
Proc Inst Mech Eng H, 228 (10) :1014-1026
2014
DOI:10.1177/0954411914554244
File:http://www.ncbi.nlm.nih.gov/pubmed/25319550
637.
Kanter, B.; Geffers, M.; Ignatius, A.; Gbureck, U.
Control of in vivo mineral bone cement degradation
Acta Biomater, 10 (7) :3279-87
2014
DOI:10.1016/j.actbio.2014.04.020
File:http://www.ncbi.nlm.nih.gov/pubmed/24769112
636.
Galbusera, F.; Taschieri, S.; Tsesis, I.; Francetti, L.; Del Fabbro, M.
Finite element simulation of implant placement following extraction of a single tooth
J Appl Biomater Funct Mater, 12 (2) :e84-9
2014
DOI:10.5301/JABFM.5000178
File:http://www.ncbi.nlm.nih.gov/pubmed/24425378
635.
Röderer, G.; Gebhard, F.; Dürselen, L.; Ignatius, A.; Claes, L.
Delayed bone healing following high tibial osteotomy related to increased implant stiffness in locked plating
Injury, 45 (10) :1648-1652
2014
DOI:10.1016/j.injury.2014.04.018
File:http://www.ncbi.nlm.nih.gov/pubmed/24813098
634.
Simon, M. J.; Beil, F. T.; Ruther, W.; Busse, B.; Koehne, T.; Steiner, M.; Pogoda, P.; Ignatius, A.; Amling, M.; Oheim, R.
High fluoride and low calcium levels in drinking water is associated with low bone mass, reduced bone quality and fragility fractures in sheep
Osteoporos Int, 25 (7) :1891-903
2014
DOI:10.1007/s00198-014-2707-4
File:http://www.ncbi.nlm.nih.gov/pubmed/24777741
633.
Goldberg-Bockhorn, E.; Schwarz, S.; Elsasser, A.; Seitz, A.; Korber, L.; Dürselen, L.; Ignatius, A.; Feldmann, E. M.; Scheithauer, M.; Breiter, R.; Rotter, N.
[Physical Characterization of Decellularized Cartilage Matrix for Reconstructive Rhinosurgery.]
Laryngorhinootologie, 93 (11) :756-763
2014
DOI:10.1055/s-0034-1384531
File:http://www.ncbi.nlm.nih.gov/pubmed/25369160
632.
Büttner-Janz, K.; Meyer, B.; Sambale, R.; Wilke, H. J.; Rüdiger, N.; Büttner, E.
FRISBEE - The First Artificial Cervical Disc of 3rd Generation
Coluna, 13 (1) :43-8
2014
631.
Schmidt, H.; Bashkuev, M.; Galbusera, F.; Wilke, H. J.; Shirazi-Adl, A.
Finite element study of human lumbar disc nucleus replacements
Comput Methods Biomech Biomed Engin, 17 (16) :1762-76
2014
DOI:10.1080/10255842.2013.766722
File:http://www.ncbi.nlm.nih.gov/pubmed/23477684
630.
Freutel, M.; Schmidt, H.; Dürselen, L.; Ignatius, A.; Galbusera, F.
Finite element modeling of soft tissues: Material models, tissue interaction and challenges
Clin Biomech (Bristol, Avon), 29 (4) :363-372
2014
DOI:10.1016/j.clinbiomech.2014.01.006
File:http://www.ncbi.nlm.nih.gov/pubmed/24529470
629.
Wehrle, E.; Wehner, T.; Heilmann, A.; Bindl, R.; Claes, L.; Jakob, F.; Amling, M.; Ignatius, A.
Distinct frequency dependent effects of whole-body vibration on non-fractured bone and fracture healing in mice
J Orthop Res, 32 (8) :1006-1013
2014
DOI:10.1002/jor.22629
File:http://www.ncbi.nlm.nih.gov/pubmed/24729351
628.
Steiner, M.; Claes, L.; Ignatius, A.; Simon, U.; Wehner, T.
Disadvantages of interfragmentary shear on fracture healing-mechanical insights through numerical simulation
J Orthop Res, 32 (7) :865-72
2014
DOI:10.1002/jor.22617
File:http://www.ncbi.nlm.nih.gov/pubmed/24648331
627.
Thormann, U.; Khawassna, T. E.; Ray, S.; Dürselen, L.; Kampschulte, M.; Lips, K. S.; Dewitz, H.; Heinemann, S.; Heiss, C.; Szalay, G.; Langheinrich, A. C.; Ignatius, A.; Schnettler, R.; Alt, V.
Differences of bone healing in metaphyseal defect fractures between osteoporotic and physiological bone in rats
Injury, 45 (3) :487-493
2014
DOI:10.1016/j.injury.2013.10.033
File:http://www.ncbi.nlm.nih.gov/pubmed/24332464
626.
Gumpert, R.; Bodo, K.; Spuller, E.; Poglitsch, T.; Bindl, R.; Ignatius, A.; Puchwein, P.
Demineralization after balloon kyphoplasty with calcium phosphate cement: a histological evaluation in ten patients
Eur Spine J, 23 (6) :1361-8
2014
DOI:10.1007/s00586-014-3239-5
File:http://www.ncbi.nlm.nih.gov/pubmed/24566944

2013

625.
Hecht, E.; Liedert, A.; Ignatius, A.; Mizaikoff, B.
Local detection of mechanically induced ATP release from bone cells with ATP microbiosensors
Biosens Bioelectron, 44C :27-33
2013
DOI:10.1016/j.bios.2013.01.008
File:http://www.ncbi.nlm.nih.gov/pubmed/23384767
624.
Garcia, P.; Histing, T.; Holstein, J. H.; Klein, M.; Laschke, M. W.; Matthys, R.; Ignatius, A.; Wildemann, B.; Lienau, J.; Peters, A.; Willie, B.; Duda, G.; Claes, L.; Pohlemann, T.; Menger, M. D.
Rodent animal models of delayed bone healing and non-union formation: a comprehensive review
Eur Cell Mater, 26 :1-14
2013
File:http://www.ncbi.nlm.nih.gov/pubmed/23857280
623.
Bindl, R.; Oheim, R.; Pogoda, P.; Beil, F. T.; Gruchenberg, K.; Reitmaier, S.; Wehner, T.; Calzia, E.; Radermacher, P.; Claes, L.; Amling, M.; Ignatius, A.
Metaphyseal fracture healing in a sheep model of low turnover osteoporosis induced by hypothalamic-pituitary disconnection (HPD)
J Orthop Res, 31 (11) :1851-1857
2013
DOI:10.1002/jor.22416
File:http://www.ncbi.nlm.nih.gov/pubmed/23813786
622.
Brown, J.; Sandmann, A.; Ignatius, A.; Amling, M.; Barvencik, F.
New perspectives on vitamin D food fortification based on a modeling of 25(OH)D concentrations
Nutr J, 12 (1) :1-12
2013
DOI:10.1186/1475-2891-12-151
File:http://www.ncbi.nlm.nih.gov/pubmed/24261676
621.
Brown, J.; Ignatius, A.; Amling, M.; Barvencik, F.
New perspectives on vitamin D sources in Germany based on a novel mathematical bottom-up model of 25(OH)D serum concentrations
Eur J Nutr, 52 (7) :1733-1742
2013
DOI:10.1007/s00394-012-0477-3
File:http://www.ncbi.nlm.nih.gov/pubmed/23229408
620.
Steiner, M.; Claes, L.; Ignatius, A.; Niemeyer, F.; Simon, U.; Wehner, T.
Prediction of fracture healing under axial loading, shear loading and bending is possible using distortional and dilatational strains as determining mechanical stimuli
J R Soc Interface, 10 (86) :20130389
2013
DOI:10.1098/rsif.2013.0389
File:http://www.ncbi.nlm.nih.gov/pubmed/23825112
619.
Reitmaier, S.; Schmidt, H.; Ihler, R.; Kocak, T.; Graf, N.; Ignatius, A.; Wilke, H. J.
Preliminary Investigations on Intradiscal Pressures during Daily Activities: An In Vivo Study Using the Merino Sheep
PLoS One, 8 (7) :e69610
2013
DOI:10.1371/journal.pone.0069610
File:http://www.ncbi.nlm.nih.gov/pubmed/23894509
618.
Heilmann, A.; Schinke, T.; Bindl, R.; Wehner, T.; Rapp, A.; Haffner-Luntzer, M.; Nemitz, C.; Liedert, A.; Amling, M.; Ignatius, A.
The Wnt Serpentine Receptor Frizzled-9 Regulates New Bone Formation in Fracture Healing
PLoS One, 8 (12) :e84232
2013
DOI:10.1371/journal.pone.0084232
File:http://www.ncbi.nlm.nih.gov/pubmed/24391920
617.
Oheim, R.; Beil, F. T.; Kohne, T.; Wehner, T.; Barvencik, F.; Ignatius, A.; Amling, M.; Clarke, I. J.; Pogoda, P.
Sheep Model for Osteoporosis: Sustainability and Biomechanical Relevance of Low Turnover Osteoporosis Induced by Hypothalamic-Pituitary Disconnection
J Orthop Res, 31 (7) :1067-1074
2013
DOI:10.1002/jor.22327
File:http://www.ncbi.nlm.nih.gov/pubmed/23440966
616.
Seitz, A.M.; Galbusera, F.; Krais, C.; Ignatius, A.; Dürselen, L.
Stress-relaxation response of human menisci under confined compression conditions
J Mech Behav Biomed Mater, 26C :68-80
2013
DOI:10.1016/j.jmbbm.2013.05.027
File:http://www.ncbi.nlm.nih.gov/pubmed/23811278
615.
Recknagel, S.; Bindl, R.; Brochhausen, C.; Göckelmann, M.; Wehner, T.; Schoengraf, P.; Huber-Lang, M.; Claes, L.; Ignatius, A.
Systemic inflammation induced by a thoracic trauma alters the cellular composition of the early fracture callus
J Trauma Acute Care Surg, 74 (2) :531-7
2013
DOI:10.1097/TA.0b013e318278956d
File:http://www.ncbi.nlm.nih.gov/pubmed/23354247
614.
Heilmann, A.; Schinke, T.; Bindl, R.; Wehner, T.; Rapp, A.; Haffner-Luntzer, M.; Liedert, A.; Amling, M.; Ignatius, A.
Systemic treatment with the sphingosine-1-phosphate analog FTY720 does not improve fracture healing in mice
J Orthop Res, 31 (11) :1845-1850
2013
DOI:10.1002/jor.22426
File:http://www.ncbi.nlm.nih.gov/pubmed/23818033
613.
Huber-Lang, M.; Kovtun, A.; Ignatius, A.
The role of complement in trauma and fracture healing
Semin Immunol, 25 (1) :73-8
2013
DOI:10.1016/j.smim.2013.05.006
File:http://www.ncbi.nlm.nih.gov/pubmed/23768898
612.
Spiro, A. S.; Khadem, S.; Jeschke, A.; Marshall, R. P.; Pogoda, P.; Ignatius, A.; Amling, M.; Beil, F. T.
The SERM raloxifene improves diaphyseal fracture healing in mice
J Bone Miner Metab, 31 (6) :629-636
2013
DOI:10.1007/s00774-013-0461-x
File:http://www.ncbi.nlm.nih.gov/pubmed/23546819
611.
Neuerburg, C.; Recknagel, S.; Fiedler, J.; Groll, J.; Moeller, M.; Bruellhoff, K.; Reichel, H.; Ignatius, A.; Brenner, R. E.
Ultrathin sP(EO-stat-PO) hydrogel coatings are biocompatible and preserve functionality of surface bound growth factors in vivo
J Mater Sci Mater Med, 24 (10) :2417-27
2013
DOI:10.1007/s10856-013-4984-4
File:http://www.ncbi.nlm.nih.gov/pubmed/23801500
610.
Galbusera, F.; Wilke, H. J.; Brayda-Bruno, M.; Costa, F.; Fornari, M.
Influence of sagittal balance on spinal lumbar loads: A numerical approach
Clin Biomech (Bristol, Avon), 28 (4) :370-377
2013
DOI:10.1016/j.clinbiomech.2013.02.006
File:http://www.ncbi.nlm.nih.gov/pubmed/23489477
609.
Schmidt, H.; Reitmaier, S.
Is the ovine intervertebral disc a small human one? A finite element model study
J Mech Behav Biomed Mater, 17 :229-41
2013
DOI:10.1016/j.jmbbm.2012.09.010
File:http://www.ncbi.nlm.nih.gov/pubmed/23127644
608.
Govindarajan, P.; Khassawna, T.; Kampschulte, M.; Böcker, W.; Huerter, B.; Dürselen, L.; Faulenbach, M.; Heiss, C.
Implications of combined ovariectomy and glucocorticoid (dexamethasone) treatment on mineral, microarchitectural, biomechanical and matrix properties of rat bone
Int J Exp Pathol, 94 (6) :387--98
2013
DOI:10.1111/iep.12038
File:http://www.ncbi.nlm.nih.gov/pubmed/23998329
607.
Nelitz, M.; Seitz, A. M.; Bauer, J.; Reichel, H.; Ignatius, A.; Dürselen, L.
Increasing posterior tibial slope does not raise anterior cruciate ligament strain but decreases tibial rotation ability
Clin Biomech (Bristol, Avon), 28 (3) :285-290
2013
DOI:10.1016/j.clinbiomech.2013.01.011
File:http://www.ncbi.nlm.nih.gov/pubmed/23489478
606.
Schmidt, H.; Bashkuev, M.; Dreischarf, M.; Rohlmann, A.; Duda, G.; Wilke, H. J.; Shirazi-Adl, A.
Computational biomechanics of a lumbar motion segment in pure and combined shear loads
J Biomech, 46 (14) :2513-2521
2013
DOI:10.1016/j.jbiomech.2013.06.038
File:http://www.ncbi.nlm.nih.gov/pubmed/23953504
605.
Epari, D. R.; Wehner, T.; Ignatius, A.; Schuetz, M. A.; Claes, L. E.
A case for optimising fracture healing through inverse dynamization
Med Hypotheses, 81 (2) :225-7
2013
DOI:10.1016/j.mehy.2013.04.044
File:http://www.ncbi.nlm.nih.gov/pubmed/23688741
604.
Alt, V.; Thormann, U.; Ray, S.; Zahner, D.; Dürselen, L.; Lips, K. S.; El Khassawna, T.; Heiss, C.; Riedrich, A.; Schlewitz, G.; Ignatius, A.; Kampschulte, M.; Dewitz, H. V.; Heinemann, S.; Schnettler, R.; Langheinrich, A. C.
A new metaphyseal bone defect model in osteoporotic rats to study effects of biomaterials for the enhancement of bone healing in osteoporotic fractures
Acta Biomater, 9 (6) :7035-7042
2013
DOI:10.1016/j.actbio.2013.02.002
File:http://www.ncbi.nlm.nih.gov/pubmed/23434894
603.
Bieger, R.; Ignatius, A.; Reichel, H.; Dürselen, L.
Biomechanics of a Short Stem: In Vitro Primary Stability and Stress Shielding of a Conservative Cementless Hip Stem
J Orthop Res, 31 (8) :1180-1186
2013
DOI:10.1002/jor.22349
File:http://www.ncbi.nlm.nih.gov/pubmed/23553802
602.
Wilke, H. J.; Schmidt, H.; Kienle, A.
Biomechanische Forschung – von der Testung zur klinischen Anwendung
Trauma und Berufskrankheit, 15 (4) :249-258
2013
DOI:10.1007/s10039-013-2044-4
File:http://dx.doi.org/10.1007/s10039-013-2044-4
601.
Tautzenberger, A.; Zwerger, C.; Dmochewitz, L.; Kreja, L.; Ignatius, A.
C3 rho-inhibitor for targeted pharmacological manipulation of osteoclast-like cells
PLoS One, 8 (12) :e85695
2013
DOI:10.1371/journal.pone.0085695
File:http://www.ncbi.nlm.nih.gov/pubmed/24386487
600.
Wilke, H. J.; Widmann, L.; Heuer, F.; Graf, N.; Rath, S.
Can prevention of a re-herniation be investigated?: Establishment of a herniation model and experiments with an anular closure device
Spine (Phila Pa 1976), 38 (10) :E587-E593
2013
DOI:10.1097/BRS.0b013e31828ca4bc
File:http://www.ncbi.nlm.nih.gov/pubmed/23429676
599.
Ehrnthaller, C.; Huber-Lang, M.; Nilsson, P.; Bindl, R.; Redeker, S.; Recknagel, S.; Rapp, A.; Mollnes, T.; Amling, M; Gebhard, F.; Ignatius, A
Complement C3 and C5 deficiency affects fracture healing
PLoS One, 8 (11) :e81341
2013
598.
Jakob, F.; Ebert, R.; Ignatius, A.; Matsushita, T.; Watanabe, Y.; Groll, J.; Walles, H.
Bone tissue engineering in osteoporosis
Maturitas, 75 (2) :118-124
2013
DOI:10.1016/j.maturitas.2013.03.004
File:http://www.ncbi.nlm.nih.gov/pubmed/23562167
597.
Recknagel, S.; Bindl, R.; Wehner, T.; Göckelmann, M.; Wehrle, E.; Gebhard, F.; Huber-Lang, M.; Claes, L.; Ignatius, A.
Conversion from external fixator to intramedullary nail causes a second hit and impairs fracture healing in a severe trauma model
J Orthop Res, 31 (3) :465-71
2013
DOI:10.1002/jor.22242
File:http://www.ncbi.nlm.nih.gov/pubmed/23070742
596.
Galbusera, F.; Tornese, D. Z.; Anasetti, F.; Bersini, S.; Volpi, P.; La Barbera, L.; Villa, T.
Does soccer cleat design influence the rotational interaction with the playing surface?
Sports Biomechanics, 12 (3) :293-301
2013
595.
Galbusera, F.; Mietsch, A.; Schmidt, H.; Wilke, H. J.; Neidlinger-Wilke, C.
Effect of intervertebral disc degeneration on disc cell viability: a numerical investigation
Comput Methods Biomech Biomed Engin, 16 (3) :328-337
2013
DOI:10.1080/10255842.2011.619184
File:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=21970697
594.
El Khassawna, T.; Böcker, W.; Govindarajan, P.; Schliefke, N.; Hürter, B.; Kampschulte, M.; Schlewitz, G.; Alt, V.; Lips, K. S.; Faulenbach, M.; Mollmann, H.; Zahner, D.; Dürselen, L.; Ignatius, A.; Bauer, N.; Wenisch, S.; Langheinrich, A. C.; Schnettler, R.; Heiss, C.
Effects of multi-deficiencies-diet on bone parameters of peripheral bone in ovariectomized mature rat
PLoS One, 8 (8) :e71665
2013
DOI:10.1371/journal.pone.0071665
File:http://www.ncbi.nlm.nih.gov/pubmed/23977109
593.
Mietsch, A.; Neidlinger-Wilke, C.; Schrezenmeier, H.; Mauer, U. M.; Friemert, B.; Wilke, H. J.; Ignatius, A.
Evaluation of platelet-rich plasma and hydrostatic pressure regarding cell differentiation in nucleus pulposus tissue engineering
J Tissue Eng Regen Med, 7 (3) :244-52
2013
DOI:10.1002/term.524
File:http://www.ncbi.nlm.nih.gov/pubmed/22162329
592.
Rojewski, M. T.; Fekete, N.; Baila, S.; Nguyen, K.; Furst, D.; Antwiler, D.; Dausend, J.; Kreja, L.; Ignatius, A.; Sensebe, L.; Schrezenmeier, H.
GMP-compliant isolation and expansion of bone marrow-derived MSCs in the closed, automated device Quantum Cell Expansion system
Cell Transplant, 22 (11) :1981-2000
2013
DOI:10.3727/096368912X657990
File:http://www.ncbi.nlm.nih.gov/pubmed/23107560
591.
Hengartner, N. E.; Fiedler, J.; Ignatius, A.; Brenner, R. E.
IL1Binhibits human osteoblast migration
Mol Med, 19 (1) :36-42
2013
DOI:10.2119/molmed.2012.00058
File:http://www.ncbi.nlm.nih.gov/pubmed/23508571
590.
Schoengraf, P.; Lambris, J. D.; Recknagel, S.; Kreja, L.; Liedert, A.; Brenner, R. E.; Huber-Lang, M.; Ignatius, A.
Does complement play a role in bone development and regeneration?
Immunobiology, 218 (1) :1-9
2013
DOI:S0171-2985(12)00035-6 [pii] 10.1016/j.imbio.2012.01.020
File:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=22464814

2012

589.
Beil, F. T.; Oheim, R.; Barvencik, F.; Hissnauer, T. N.; Pestka, J. M.; Ignatius, A.; Rueger, J. M.; Schinke, T.; Clarke, I. J.; Amling, M.; Pogoda, P.
Low turnover osteoporosis in sheep induced by hypothalamic-pituitary disconnection
J Orthop Res, 30 (8) :1254-62
2012
DOI:10.1002/jor.22066
File:http://www.ncbi.nlm.nih.gov/pubmed/22234948
588.
Calzia, E.; Huber-Lang, M.; Ignatius, A.; Radermacher, P.; Thiemermann, A. C.
Modeling traumatic-hemorrhagic shock-nothing is simple and easy
Shock, 38 (6) :685-6
2012
DOI:10.1097/SHK.0b013e3182756a24
File:http://www.ncbi.nlm.nih.gov/pubmed/23160522
587.
Ciavarro, C.; Caiani, E. G.; Brayda-Bruno, M.; Zerbi, A.; Galbusera, F.; Vaga, S.; Lamartina, C.
Mid-term evaluation of the effects of dynamic neutralization system on lumbar intervertebral discs using quantitative molecular MR imaging
J Magn Reson Imaging, 35 (5) :1145-1151
2012
DOI:10.1002/jmri.23525
File:http://www.ncbi.nlm.nih.gov/pubmed/22128094
586.
Galbusera, F.; Schmidt, H.; Wilke, H. J.
Lumbar interbody fusion: a parametric investigation of a novel cage design with and without posterior instrumentation
Eur Spine J, 21 (3) :455-62
2012
DOI:10.1007/s00586-011-2014-0
File:http://www.ncbi.nlm.nih.gov/pubmed/21918923
585.
Kettler, A.; Bushelow, M.; Wilke, H. J.
Influence of the loading frequency on the wear rate of a polyethylene-on-metal lumbar intervertebral disc replacement
Eur Spine J, 21 (Suppl 5) :S709-S716
2012
DOI:10.1007/s00586-010-1582-8
File:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=20936310
584.
Oheim, R.; Amling, M.; Ignatius, A.; Pogoda, P.
Large animal model for osteoporosis in humans: the ewe
Eur Cell Mater, 24 :372-85
2012
File:http://www.ncbi.nlm.nih.gov/pubmed/23147526
583.
Wilke, H. J.; Zanker, D.; Wolfram, U.
Internal morphology of human facet joints: comparing cervical and lumbar spine with regard to age, gender and the vertebral core
J Anat, 220 (3) :233-241
2012
DOI:10.1111/j.1469-7580.2011.01465.x
File:http://www.ncbi.nlm.nih.gov/pubmed/22257304
582.
Neidlinger-Wilke, C.; Mietsch, A.; Rinkler, C.; Wilke, H. J.; Ignatius, A.; Urban, J.
Interactions of environmental conditions and mechanical loads have influence on matrix turnover by nucleus pulposus cells
J Orthop Res, 30 (1) :112-21
2012
DOI:10.1002/jor.21481
File:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=21674606
581.
Wehner, T.; Claes, L.; Ignatius, A.; Simon, U.
Optimization of intramedullary nailing by numerical simulation of fracture healing
J Orthop Res, 30 (4) :569-73
2012
DOI:10.1002/jor.21568
File:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=22002798
580.
Tautzenberger, A.; Kovtun, A.; Ignatius, A.
Nanoparticles and their potential for application in bone
Int J Nanomedicine, 7 :4545-57
2012
DOI:10.2147/IJN.S34127
File:http://www.ncbi.nlm.nih.gov/pubmed/22923992
579.
Wilke, H. J.; Schmidt, R.; Richter, M.; Schmölz, W.; Reichel, H.; Cakir, B.
The role of prosthesis design on segmental biomechanics : Semi-constrained versus unconstrained prostheses and anterior versus posterior centre of rotation
Eur Spine J, 21 (Suppl 5) :S557-S584
2012
DOI:10.1007/s00586-010-1552-1
File:http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=20830492
578.
Harms, C.; Helms, K.; Taschner, T.; Stratos, I.; Ignatius, A.; Gerber, T.; Lenz, S.; Rammelt, S.; Vollmar, B.; Mittlmeier, T.
Osteogenic capacity of nanocrystalline bone cement in a weight-bearing defect at the ovine tibial metaphysis
Int J Nanomedicine, 7 :2883-9
2012
DOI:10.2147/IJN.S29314
File:http://www.ncbi.nlm.nih.gov/pubmed/22745551

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