Institute of Orthopaedic Research and Biomechanics

Publications

You find here a complete list of publications authored or coauthered by members of our institute since 1974. By default the entire list is presented.

2017

764.
Wilke, H. J.; Herkommer, A.; Werner, K.; Liebsch, C.
In vitro analysis of the segmental flexibility of the thoracic spine
PLoS One, 12 (5) :e0177823
2017
DOI:10.1371/journal.pone.0177823
File:https://www.ncbi.nlm.nih.gov/pubmed/28520819
763.
Haffner-Luntzer, M; Müller-Graf, F; Matthys, R.; Abaei, A; Jonas, R.; Gebhard, F.; Rasche, V.; Ignatius, A
In Vivo Evaluation of Fracture Callus Development During Bone Healing in Mice Using an MRI-compatible Osteosynthesis Device for the Mouse Femur
J Vis Exp (129) :e56679
2017
DOI:doi:10.3791/56679
762.
Berger-Roscher, N.; Casaroli, G.; Rasche, V.; Villa, T.; Galbusera, F.; Wilke, H. J.
Influence of Complex Loading Conditions on Intervertebral Disc Failure
Spine (Phila Pa 1976), 42 (2) :E78-E85
2017
DOI:10.1097/BRS.0000000000001699
File:http://www.ncbi.nlm.nih.gov/pubmed/27187053
761.
Drews, B. H.; Seitz, A.; Huth, J.; Bauer, G.; Ignatius, A.; Dürselen, L.
Influence of tibial hybrid fixation on graft tension and stability in ACL double-bundle reconstruction
Arch Orthop Trauma Surg, 137 (7) :981–988
2017
DOI:10.1007/s00402-017-2698-7
File:https://www.ncbi.nlm.nih.gov/pubmed/28424860
760.
Volkheimer, D.; Reichel, H.; Wilke, H. J.; Lattig, F.
Is pelvic fixation the only option to provide additional stability to the sacral anchorage in long lumbar instrumentation? A comparative biomechanical study of new techniques
Clin Biomech (Bristol, Avon), 43 :34-39
2017
DOI:10.1016/j.clinbiomech.2017.02.001
File:https://www.ncbi.nlm.nih.gov/pubmed/28199880
759.
Kroner, J.; Kovtun, A.; Kemmler, J.; Messmann, J. J.; Strauss, G.; Seitz, S.; Schinke, T.; Amling, M.; Kotrba, J.; Dudeck, J.; Dudeck, A.; Ignatius, A.
Mast cells are critical regulators of bone fracture-induced inflammation and osteoclast formation and activity
J Bone Miner Res, 32 (12) :2431–2444
2017
DOI:10.1002/jbmr.3234
File:https://www.ncbi.nlm.nih.gov/pubmed/28777474
758.
Blum, Carina; Brückner, Theresa; Ewald, Andrea; Gbureck, Uwe
Mg:Ca ratio as regulating factor for osteoclastic in vitro resorption of struvite biocements
Mater Sci Eng C, 73 :111-119
2017
DOI:http://dx.doi.org/10.1016/j.msec.2016.12.002
File:http://www.sciencedirect.com/science/article/pii/S0928493116325097
757.
Rijsbergen, M. M.; Barthelemy, V. M.; Vrancken, A. C.; Crijns, S. P.; Wilke, H. J.; Wilson, W.; Rietbergen, B.; Ito, K.
Moderately degenerated lumbar motion segments: Are they truly unstable?
Biomech Model Mechanobiol, 16 (2) :537-547
2017
DOI:10.1007/s10237-016-0835-9
File:http://www.ncbi.nlm.nih.gov/pubmed/27664020
756.
Bartnikowski, N.; Claes, L. E.; Koval, L.; Glatt, V.; Bindl, R.; Steck, R.; Ignatius, A.; Schuetz, M. A.; Epari, D. R.
Modulation of fixation stiffness from flexible to stiff in a rat model of bone healing
Acta Orthop, 88 (2) :217-222
2017
DOI:10.1080/17453674.2016.1256940
File:https://www.ncbi.nlm.nih.gov/pubmed/27841708
755.
Meyers, N.; Schulke, J.; Ignatius, A.
Novel systems for the application of isolated tensile, compressive, and shearing stimulation of distraction callus tissue
PLoS One, 12 (12) :e0189432
2017
DOI:10.1371/journal.pone.0189432
File:https://www.ncbi.nlm.nih.gov/pubmed/29228043
754.
Casaroli, Gloria; Villa, Tomaso; Bassani, Tito; Berger-Roscher, Nikolaus; Wilke, Hans-Joachim; Galbusera, Fabio
Numerical Prediction of the Mechanical Failure of the Intervertebral Disc under Complex Loading Conditions
Materials, 10 (1) :31
2017
File:http://www.mdpi.com/1996-1944/10/1/31
753.
Bergdolt, S.; Kovtun, A.; Hagele, Y.; Liedert, A.; Schinke, T.; Amling, M.; Huber-Lang, M.; Ignatius, A.
Osteoblast-specific overexpression of complement receptor C5aR1 impairs fracture healing
PLoS One, 12 (6) :e0179512
2017
DOI:10.1371/journal.pone.0179512
File:https://www.ncbi.nlm.nih.gov/pubmed/28614388
752.
El Khassawna, T.; Merboth, F.; Malhan, D.; Böcker, W.; Daghma, D. E. S.; Stoetzel, S.; Kern, S.; Hassan, F.; Rosenbaum, D.; Langenstein, J.; Bauer, N.; Schlagenhauf, A.; Rosen-Wolff, A.; Schulze, F.; Rupp, M.; Hose, D.; Secklinger, A.; Ignatius, A.; Wilke, H. J.; Lips, K. S.; Heiss, C.
Osteocyte Regulation of Receptor Activator of NF-kappaB Ligand/Osteoprotegerin in a Sheep Model of Osteoporosis
Am J Pathol, 187 (8) :1686-1699
2017
DOI:10.1016/j.ajpath.2017.04.005
File:https://www.ncbi.nlm.nih.gov/pubmed/28618255
751.
Meininger, S.; Blum, C.; Schamel, M.; Barralet, J. E.; Ignatius, A.; Gbureck, U.
Phytic acid as alternative setting retarder enhanced biological performance of dicalcium phosphate cement in vitro
Sci Rep, 7 (1) :558
2017
DOI:10.1038/s41598-017-00731-6
File:https://www.ncbi.nlm.nih.gov/pubmed/28373697
750.
La Barbera, L.; Galbusera, F.; Wilke, H. J.; Villa, T.
Preclinical evaluation of posterior spine stabilization devices: can we compare in vitro and in vivo loads on the instrumentation?
Eur Spine J, 26 (1) :200-209
2017
DOI:10.1007/s00586-016-4766-z
File:http://www.ncbi.nlm.nih.gov/pubmed/27637903
749.
Bassani, Tito; Ottardi, Claudia; Costa, Francesco; Brayda-Bruno, Marco; Wilke, Hans-Joachim; Galbusera, Fabio
Semiautomated 3D Spine Reconstruction from Biplanar Radiographic Images: Prediction of Intervertebral Loading in Scoliotic Subjects
Front Bioeng Biotechnol, 5 (1)
2017
DOI:10.3389/fbioe.2017.00001
File:http://journal.frontiersin.org/article/10.3389/fbioe.2017.00001
748.
Oheim, R.; Simon, M. J.; Steiner, M.; Vettorazzi, E.; Barvencik, F.; Ignatius, A.; Amling, M.; Clarke, I. J.; Pogoda, P.; Beil, F. T.
Sheep model for osteoporosis: The effects of peripheral hormone therapy on centrally induced systemic bone loss in an osteoporotic sheep model
Injury, 48 (4) :841-848
2017
DOI:10.1016/j.injury.2017.02.009
File:http://www.ncbi.nlm.nih.gov/pubmed/28237183
747.
Gačanin, Jasmina; Kovtun, Anna; Schwager, Victoria; Quambusch, Johanna; Li, Chuang; Yang, Zhongqiang; Liu, Dongsheng
Spatiotemporally Controlled Release of Rho-Inhibiting C3 Toxin from a Protein–DNA Hybrid Hydrogel for Targeted Inhibition of Osteoclast Formation and Activity
Adv Healthc Mater, 6 (21) :1700392
2017
DOI:10.1002/adhm.201700392
File:http://dx.doi.org/10.1002/adhm.201700392
746.
Reitmaier, S.; Schuelke, J.; Volkheimer, D.; Ignatius, A.; Wilke, H. J.
Spinal fusion without instrumentation - Experimental animal study
Clin Biomech (Bristol, Avon), 46 :6-14
2017
DOI:10.1016/j.clinbiomech.2017.04.008
File:https://www.ncbi.nlm.nih.gov/pubmed/28463696
745.
Dex, S.; Alberton, P.; Willkomm, L.; Sollradl, T.; Bago, S.; Milz, S.; Shakibaei, M.; Ignatius, A.; Bloch, W.; Clausen-Schaumann, H.; Shukunami, C.; Schieker, M.; Docheva, D.
Tenomodulin is Required for Tendon Endurance Running and Collagen I Fibril Adaptation to Mechanical Load
EBioMedicine, 20 :240-254
2017
DOI:10.1016/j.ebiom.2017.05.003
File:https://www.ncbi.nlm.nih.gov/pubmed/28566251
744.
Gebhard, F.; Ignatius, A.; Lechner, R.; Baumgartel, S.; Kraus, M.; Krischak, G. D.
The effect of a combined thoracic and soft-tissue trauma on blood flow and tissue formation in fracture healing in rats
Arch Orthop Trauma Surg, 137 (7) :945-952
2017
DOI:10.1007/s00402-017-2695-x
File:https://www.ncbi.nlm.nih.gov/pubmed/28429082
743.
Haffner-Luntzer, M; Fischer, V.; Prystaz, K.; Liedert, A.; Ignatius, A
The inflammatory phase of fracture healing is influenced by oestrogen status in mice
Eur J Med Res, 33 (1) :23
2017
DOI:DOI 10.1186/s40001‐017‐0264‐y
742.
Liebsch, C.; Graf, N.; Appelt, K.; Wilke, H. J.
The rib cage stabilizes the human thoracic spine: An in vitro study using stepwise reduction of rib cage structures
PLoS One, 12 (6) :e0178733
2017
DOI:10.1371/journal.pone.0178733
File:https://www.ncbi.nlm.nih.gov/pubmed/28570671
741.
Ehrnthaller, C.; Olivier, A. C.; Gebhard, F.; Dürselen, L.
The role of lesser trochanter fragment in unstable pertrochanteric A2 proximal femur fractures - is refixation of the lesser trochanter worth the effort?
Clin Biomech (Bristol, Avon), 42 (1) :31-37
2017
DOI:10.1016/j.clinbiomech.2016.12.013
File:https://www.ncbi.nlm.nih.gov/pubmed/28073094
740.
Wilke, H. J.; Volkheimer, D.; Robie, B.; Christensen, F. B.
Two-piece ALIF cage optimizes the bone-implant interface in a 360 degrees setting
Eur Spine J, 26 (11) :2747-2753
2017
DOI:10.1007/s00586-017-5009-7
File:http://www.ncbi.nlm.nih.gov/pubmed/28247079
739.
Rolvien, T.; Hahn, M.; Siebert, U.; Puschel, K.; Wilke, H. J.; Busse, B.; Amling, M.; Oheim, R.
Vertebral bone microarchitecture and osteocyte characteristics of three toothed whale species with varying diving behaviour
Sci Rep, 7 (1) :1604
2017
DOI:10.1038/s41598-017-01926-7
File:https://www.ncbi.nlm.nih.gov/pubmed/28487524
738.
Liebsch, C.; Graf, N.; Wilke, H. J.
Wire cerclage can restore the stability of the thoracic spine after median sternotomy: an in vitro study with entire rib cage specimens
Eur Spine J, 26 (5) :1401-1407
2017
DOI:10.1007/s00586-016-4768-x
File:http://www.ncbi.nlm.nih.gov/pubmed/27639711

2016

737.
Teixeira, G. Q.; Boldt, A.; Nagl, I.; Pereira, C. L.; Benz, K.; Wilke, H. J.; Ignatius, A.; Barbosa, M. A.; Goncalves, R. M.; Neidlinger-Wilke, C.
A Degenerative/Proinflammatory Intervertebral Disc Organ Culture: An Ex Vivo Model for Anti-inflammatory Drug and Cell Therapy
Tissue Eng Part C Methods, 22 (1) :8-19
2016
DOI:10.1089/ten.tec.2015.0195
File:http://www.ncbi.nlm.nih.gov/pubmed/26565141
736.
Wilke, H. J.; Kienle, A.; Maile, S.; Rasche, V.; Berger-Roscher, N.
A new dynamic six degrees of freedom disc-loading simulator allows to provoke disc damage and herniation
Eur Spine J, 25 (5) :1363-72
2016
DOI:10.1007/s00586-016-4416-5
File:http://www.ncbi.nlm.nih.gov/pubmed/26838335
735.
Wilke, H. J.; Kaiser, D.; Volkheimer, D.; Hackenbroch, C.; Puschel, K.; Rauschmann, M.
A pedicle screw system and a lamina hook system provide similar primary and long-term stability: a biomechanical in vitro study with quasi-static and dynamic loading conditions
Eur Spine J, 25 (9) :2919-2928
2016
DOI:10.1007/s00586-016-4679-x
File:http://www.ncbi.nlm.nih.gov/pubmed/27405823
734.
Haffner-Luntzer, M.; Heilmann, A.; Rapp, A. E.; Roessler, R.; Schinke, T.; Amling, M.; Ignatius, A.; Liedert, A.
Antagonizing Midkine Accelerates Fracture Healing in Mice by Enhanced Bone Formation in the Fracture Callus
Br J Pharmacol, 173 (14) :2237-49
2016
DOI:10.1111/bph.13503
File:http://www.ncbi.nlm.nih.gov/pubmed/27111560
733.
Teixeira, G. Q.; Leite Pereira, C.; Castro, F.; Ferreira, J. R.; Gomez-Lazaro, M.; Aguiar, P.; Barbosa, M. A.; Neidlinger-Wilke, C.; Goncalves, R. M.
Anti-inflammatory Chitosan/Poly-gamma-glutamic acid nanoparticles control inflammation while remodeling extracellular matrix in degenerated intervertebral disc
Acta Biomater, 42 :168-179
2016
DOI:10.1016/j.actbio.2016.06.013
File:http://www.ncbi.nlm.nih.gov/pubmed/27321188
732.
Riegger, J.; Joos, H.; Palm, H. G.; Friemert, B.; Reichel, H.; Ignatius, A.; Brenner, R. E.
Antioxidative therapy in an ex vivo human cartilage trauma-model: Attenuation of trauma-induced cell loss and ECM-destructive enzymes by N-acetyl cysteine
Osteoarthritis Cartilage, 24 (12) :2171-2180
2016
DOI:10.1016/j.joca.2016.07.019
File:http://www.ncbi.nlm.nih.gov/pubmed/27514995
731.
Ehrnthaller, C.; Huber-Lang, M.; Kovtun, A.; Rapp, A. E.; Kemmler, J.; Gebhard, F.; Ignatius, A.
C5aR inhibition in the early inflammatory phase does not affect bone regeneration in a model of uneventful fracture healing
Eur J Med Res, 21 (1) :42
2016
DOI:10.1186/s40001-016-0236-7
File:https://www.ncbi.nlm.nih.gov/pubmed/27784330
730.
Pratsinis, H.; Papadopoulou, A.; Neidlinger-Wilke, C.; Brayda-Bruno, M.; Wilke, H. J.; Kletsas, D.
Cyclic tensile stress of human annulus fibrosus cells induces MAPK activation: involvement in proinflammatory gene expression
Osteoarthritis Cartilage, 24 (4) :679-87
2016
DOI:10.1016/j.joca.2015.11.022
File:http://www.ncbi.nlm.nih.gov/pubmed/26687822
729.
Simon, M. J.; Beil, F. T.; Riedel, C.; Lau, G.; Tomsia, A.; Zimmermann, E. A.; Koehne, T.; Ueblacker, P.; Ruther, W.; Pogoda, P.; Ignatius, A.; Amling, M.; Oheim, R.
Deterioration of teeth and alveolar bone loss due to chronic environmental high-level fluoride and low calcium exposure
Clin Oral Investig, 20 (9) :2361-2370
2016
DOI:10.1007/s00784-016-1727-1
File:http://www.ncbi.nlm.nih.gov/pubmed/26818581
728.
Belavy, D. L.; Adams, M.; Brisby, H.; Cagnie, B.; Danneels, L.; Fairbank, J.; Hargens, A. R.; Judex, S.; Scheuring, R. A.; Sovelius, R.; Urban, J.; Dieen, J. H.; Wilke, H. J.
Disc herniations in astronauts: What causes them, and what does it tell us about herniation on earth?
Eur Spine J, 25 (1) :144-154
2016
DOI:10.1007/s00586-015-3917-y
File:http://www.ncbi.nlm.nih.gov/pubmed/25893331
727.
Kienle, A.; Graf, N.; Wilke, H. J.
Does impaction of titanium-coated interbody fusion cages into the disc space cause wear debris and/or delamination?
Spine J, 16 :2
2016
DOI:10.1016/j.spinee.2015.09.038
File:http://www.ncbi.nlm.nih.gov/pubmed/26409208
726.
Müller, S. A.; Dürselen, L.; Heisterbach, P.; Evans, C.; Majewski, M.
Effect of a Simple Collagen Type I Sponge for Achilles Tendon Repair in a Rat Model
Am J Sports Med, 44 (8) :1998-2004
2016
DOI:10.1177/0363546516641942
File:http://www.ncbi.nlm.nih.gov/pubmed/27159286
725.
Ray, S.; Thormann, U.; Sommer, U.; Khassawna, T. E.; Hundgeburth, M.; Henss, A.; Rohnke, M.; Lips, K. S.; Heiss, C.; Heinemann, S.; Hanke, T.; Dürselen, L.; Schnettler, R.; Alt, V.
Effects of macroporous, strontium loaded xerogel-scaffolds on new bone formation in critical-size metaphyseal fracture defects in ovariectomized rats
Injury, 47 Suppl 1 :S52-61
2016
DOI:10.1016/S0020-1383(16)30013-4
File:http://www.ncbi.nlm.nih.gov/pubmed/26768293
724.
Rapp, A. E.; Bindl, R.; Recknagel, S.; Erbacher, A.; Muller, I.; Schrezenmeier, H.; Ehrnthaller, C.; Gebhard, F.; Ignatius, A.
Fracture Healing Is Delayed in Immunodeficient NOD/scidIL2Rgammacnull Mice
PLoS One, 11 (2) :e0147465
2016
DOI:10.1371/journal.pone.0147465
File:http://www.ncbi.nlm.nih.gov/pubmed/26849055
723.
Haffner-Luntzer, M.; Heilmann, A.; Heidler, V.; Liedert, A.; Schinke, T.; Amling, M.; Yorgan, T. A.; Vom Scheidt, A.; Ignatius, A.
Hypochlorhydria-induced calcium malabsorption does not affect fracture healing but increases post-traumatic bone loss in the intact skeleton
J Orthop Res, 34 (11) :1914-1921
2016
DOI:10.1002/jor.23221
File:http://www.ncbi.nlm.nih.gov/pubmed/26945509
722.
Haffner-Luntzer, M.; Kemmler, J.; Heidler, V.; Prystaz, K.; Schinke, T.; Amling, M.; Kovtun, A.; Rapp, A. E.; Ignatius, A.; Liedert, A.
Inhibition of Midkine Augments Osteoporotic Fracture Healing
PLoS One, 11 (7) :e0159278
2016
DOI:10.1371/journal.pone.0159278
File:http://www.ncbi.nlm.nih.gov/pubmed/27410432
721.
Haffner-Luntzer, M.; Liedert, A.; Ignatius, A
Mechanobiology of bone remodeling and fracture healing in the aged organism
Innov Surg Sci, 1 (2) :57-63
2016
DOI:DOI 10.1515/iss-2016-0021
720.
Haffner-Luntzer, M.; Kovtun, A.; Rapp, A.; Ignatius, A
Mouse Models in Bone Fracture Healing Research
Curr Mol Biol Rep, 2 (2) :101-111
2016
DOI:10.1007/s40610-016-0037-3
719.
La Barbera, L.; Galbusera, F.; Wilke, H. J.; Villa, T.
Preclinical evaluation of posterior spine stabilization devices: can the current standards represent basic everyday life activities?
Eur Spine J, 25 (9) :2909-2918
2016
DOI:10.1007/s00586-016-4622-1
File:http://www.ncbi.nlm.nih.gov/pubmed/27236658
718.
Bieger, R.; Freitag, T.; Ignatius, A.; Reichel, H.; Dürselen, L.
Primary stability of a shoulderless Zweymuller hip stem: a comparative in vitro micromotion study
J Orthop Surg Res, 11 (1) :73
2016
DOI:10.1186/s13018-016-0410-1
File:http://www.ncbi.nlm.nih.gov/pubmed/27380777
717.
Malakoutian, M.; Street, J.; Wilke, H. J.; Stavness, I.; Dvorak, M.; Fels, S.; Oxland, T.
Role of muscle damage on loading at the level adjacent to a lumbar spine fusion: a biomechanical analysis
Eur Spine J, 25 (9) :2929-2937
2016
DOI:10.1007/s00586-016-4686-y
File:http://www.ncbi.nlm.nih.gov/pubmed/27465240
716.
Wilke, H. J.
Spine Research Is Multidisciplinary: 25 Years of Experiences
Spine (Phila Pa 1976), 41 Suppl 7 :S1-3
2016
DOI:10.1097/BRS.0000000000001419
File:http://www.ncbi.nlm.nih.gov/pubmed/27015056
715.
Kovtun, A.; Bergdolt, S.; Wiegner, R.; Radermacher, P.; Huber-Lang, M.; Ignatius, A.
The crucial role of neutrophil granulocytes in bone fracture healing
Eur Cell Mater, 32 :152-62
2016
File:http://www.ncbi.nlm.nih.gov/pubmed/27452963
714.
Hacker, S. P.; Ignatius, A.; Dürselen, L.
The influence of the test setup on knee joint kinematics - A meta-analysis of tibial rotation
J Biomech, 49 (13) :2982-2988
2016
DOI:10.1016/j.jbiomech.2016.07.025
File:http://www.ncbi.nlm.nih.gov/pubmed/27507625

2015

713.
Wilke, H. J.
[Biomechanical aspects of vertebral augmentation]
Unfallchirurg, 118 (10) :822-830
2015
DOI:10.1007/s00113-015-0066-z
File:http://www.ncbi.nlm.nih.gov/pubmed/26358323
711.
Haffner-Luntzer, M.; Liedert, A.; Ignatius, A.
[Mechanobiology and bone metabolism : Clinical relevance for fracture treatment]
Unfallchirurg, 118 (12) :1000-6
2015
DOI:10.1007/s00113-015-0102-z
File:http://www.ncbi.nlm.nih.gov/pubmed/26577661
710.
Lips, K. S.; Kneffel, M.; Willscheid, F.; Mathies, F. M.; Kampschulte, M.; Hartmann, S.; Panzer, I.; Dürselen, L.; Heiss, C.; Kauschke, V.
Altered ultrastructure, density and cathepsin K expression in bone of female muscarinic acetylcholine receptor M3 knockout mice
Int Immunopharmacol, 29 (1) :201-207
2015
DOI:10.1016/j.intimp.2015.05.012
File:http://www.ncbi.nlm.nih.gov/pubmed/26002583 http://ac.els-cdn.com/S1567576915002349/1-s2.0-S1567576915002349-main.pdf?_tid=19c2185e-7e20-11e5-a269-00000aab0f6c&acdnat=1446111384_17d2b5252bc98d5071335b59881e9f6b http://ac.els-cdn.com/S1567576915002349/1-
709.
Rapp, A. E.; Kroner, J.; Baur, S.; Schmid, F.; Walmsley, A.; Mottl, H.; Ignatius, A.
Analgesia via blockade of NGF/TrkA signaling does not influence fracture healing in mice
J Orthop Res, 33 (8) :1235-1241
2015
DOI:10.1002/jor.22892
File:http://www.ncbi.nlm.nih.gov/pubmed/25876530
708.
Dürselen, L; Freutel, M.
Biomechanik des Meniskus
Orthopädie und Unfallchirurgie up2date, 10 (3) :215-227
2015
707.
Sörensen, JH; Dürselen, L; Welch, K; Sörensen, TC; Procter, P; Engqvist, H; Stromme, M; Ignatius, A; Steckel, H
Biomimetic Hydroxyapatite Coated Titanium Screws Demonstrate Rapid Implant Stabilization and Safe Removal In-Vivo
J Biomater Nanobiotechnol, 6 (1) :20-35
2015
DOI:http://dx.doi.org/10.4236/jbnb.2015.61003
706.
Wagner, K.; Asfar, P.; Huber-Lang, M.; Ignatius, A.; Duechs, M.; Radermacher, P.; Wagner, F.
Blunt Chest Trauma in Mice after Cigarette Smoke-Exposure: Effects of Mechanical Ventilation with 100 % O2
PLoS One, 10 (7) :e0132810
2015
DOI:10.1371/journal.pone.0132810
File:http://www.ncbi.nlm.nih.gov/pubmed/26225825
705.
Kauschke, V.; Kneffel, M.; Floel, W.; Hartmann, S.; Kampschulte, M.; Dürselen, L.; Ignatius, A.; Schnettler, R.; Heiss, C.; Lips, K. S.
Bone status of acetylcholinesterase-knockout mice
Int Immunopharmacol, 29 (1) :222-230
2015
DOI:10.1016/j.intimp.2015.07.046
File:http://www.ncbi.nlm.nih.gov/pubmed/26250336 http://ac.els-cdn.com/S1567576915300588/1-s2.0-S1567576915300588-main.pdf?_tid=2424816a-7e20-11e5-bb0c-00000aab0f01&acdnat=1446111401_5020b4d28afab4cd2bdd0bdeed30384d http://ac.els-cdn.com/S1567576915300588/1-
704.
Haupt, M.; Kauschke, V.; Sender, J.; Kampschulte, M.; Kovtun, A.; Dürselen, L.; Heiss, C.; Lips, K. S.
Bone status of adult female butyrylcholinesterase gene-deficient mice
Int Immunopharmacol, 29 (1) :208-214
2015
DOI:10.1016/j.intimp.2015.06.029
File:http://www.ncbi.nlm.nih.gov/pubmed/26138460 http://ac.els-cdn.com/S1567576915300059/1-s2.0-S1567576915300059-main.pdf?_tid=14a56452-7e20-11e5-a71f-00000aab0f26&acdnat=1446111375_6a2191e6c0577147b54c8f5410db6527 http://ac.els-cdn.com/S1567576915300059/1-
703.
Waschke, A.; Berger-Roscher, N.; Kielstein, H.; Ewald, C.; Kalff, R.; Wilke, H. J.
Cement Augmented Anterior Odontoid Screw Fixation is Biomechanically Advantageous in Osteoporotic Patients with Anderson Type II Fractures
J Spinal Disord Tech, 28 (3) :E126-32
2015
DOI:10.1097/BSD.0000000000000177
File:http://www.ncbi.nlm.nih.gov/pubmed/25310397
702.
Steiner, M.; Volkheimer, D.; Meyers, N.; Wehner, T.; Wilke, H. J.; Ignatius, A.
Comparison between Different Methods for Biomechanical Assessment of Ex Vivo Fracture Callus Stiffness in Small Animal Bone Healing Studies
PLoS One, 10 (3) :e0119603
2015
DOI:10.1371/journal.pone.0119603
File:http://www.ncbi.nlm.nih.gov/pubmed/25781027
701.
Doyle, H.; Lohfeld, S.; Dürselen, L.; McHugh, P.
Computational modelling of ovine critical-sized tibial defects with implanted scaffolds and prediction of the safety of fixator removal
J Mech Behav Biomed Mater, 44C :133-146
2015
DOI:10.1016/j.jmbbm.2015.01.008
File:http://www.ncbi.nlm.nih.gov/pubmed/25637824
700.
Wilke, H. J.; Mathes, B.; Midderhoff, S.; Graf, N.
Development of a scoliotic spine model for biomechanical in vitro studies
Clin Biomech (Bristol, Avon), 30 (2) :182-187
2015
DOI:10.1016/j.clinbiomech.2014.12.002
File:http://www.ncbi.nlm.nih.gov/pubmed/25533272
699.
Joos, H.; Leucht, F.; Riegger, J.; Hogrefe, C.; Fiedler, J.; Dürselen, L.; Reichel, H.; Ignatius, A.; Brenner, R. E.
Differential Interactive Effects of Cartilage Traumatization and Blood Exposure In Vitro and In Vivo
Am J Sports Med, 43 (11) :2822-32
2015
DOI:10.1177/0363546515602248
File:http://www.ncbi.nlm.nih.gov/pubmed/26362437 http://ajs.sagepub.com/content/early/2015/09/11/0363546515602248.long
698.
Malakoutian, M.; Volkheimer, D.; Street, J.; Dvorak, M. F.; Wilke, H. J.; Oxland, T. R.
Do in vivo kinematic studies provide insight into adjacent segment degeneration? A qualitative systematic literature review
Eur Spine J, 24 (9) :1865-1881
2015
DOI:10.1007/s00586-015-3992-0
File:http://www.ncbi.nlm.nih.gov/pubmed/26055273
697.
Kemmler, J.; Bindl, R.; Wagner, F.; Wagner, K.; Radermacher, P.; Ignatius, A.
Exposure to 100% Oxygen Abolishes the Impairment of Fracture Healing after Thoracic Trauma
PLoS One, 10 (7) :e0131194
2015
DOI:10.1371/journal.pone.0131194
File:http://www.ncbi.nlm.nih.gov/pubmed/26147725
696.
El Khassawna, T.; Böcker, W.; Brodsky, K.; Weisweiler, D.; Govindarajan, P.; Kampschulte, M.; Thormann, U.; Henss, A.; Rohnke, M.; Bauer, N.; Müller, R.; Deutsch, A.; Ignatius, A.; Dürselen, L.; Langheinrich, A.; Lips, K. S.; Schnettler, R.; Heiss, C.
Impaired extracellular matrix structure resulting from malnutrition in ovariectomized mature rats
Histochem Cell Biol, 144 (5) :491-507
2015
DOI:10.1007/s00418-015-1356-9
File:http://www.ncbi.nlm.nih.gov/pubmed/26210855
695.
Gruchenberg, K.; Ignatius, A.; Friemert, B.; Lübken, F.; Skaer, N.; Gellynck, K.; Kessler, O.; Dürselen, L.
In vivo performance of a novel silk fibroin scaffold for partial meniscal replacement in a sheep model
Knee Surg Sports Traumatol Arthrosc, 23 (8) :2218-29
2015
DOI:10.1007/s00167-014-3009-2
File:http://www.ncbi.nlm.nih.gov/pubmed/24770350
694.
Kovtun, A.; Göckelmann, M. J.; Niclas, A. A.; Montufar, E. B.; Ginebra, M. P.; Planell, J. A.; Santin, M.; Ignatius, A.
In vivo performance of novel soybean/gelatin-based bioactive and injectable hydroxyapatite foams
Acta Biomater, 12 :242-9
2015
DOI:10.1016/j.actbio.2014.10.034
File:http://www.ncbi.nlm.nih.gov/pubmed/25448348
693.
Freutel, M.; Seitz, A. M.; Ignatius, A.; Dürselen, L.
Influence of partial meniscectomy on attachment forces, superficial strain and contact mechanics in porcine knee joints
Knee Surg Sports Traumatol Arthrosc, 23 (1) :74-82
2015
DOI:10.1007/s00167-014-2951-3
File:http://www.ncbi.nlm.nih.gov/pubmed/24671386
692.
Berger-Roscher, N.; Galbusera, F.; Rasche, V.; Wilke, H. J.
Intervertebral disc lesions: visualisation with ultra-high field MRI at 11.7 T
Eur Spine J, 24 (11) :2488-2495
2015
DOI:10.1007/s00586-015-4146-0
File:http://www.ncbi.nlm.nih.gov/pubmed/26206293
691.
Volkheimer, D.; Malakoutian, M.; Oxland, T. R.; Wilke, H. J.
Limitations of current in vitro test protocols for investigation of instrumented adjacent segment biomechanics: critical analysis of the literature
Eur Spine J, 24 (9) :1882-1892
2015
DOI:10.1007/s00586-015-4040-9
File:http://www.ncbi.nlm.nih.gov/pubmed/26038156
690.
Freutel, M.; Galbusera, F.; Ignatius, A.; Dürselen, L.
Material properties of individual menisci and their attachments obtained through inverse FE-analysis
J Biomech, 48 (8) :1343-1349
2015
DOI:10.1016/j.jbiomech.2015.03.014
File:http://www.ncbi.nlm.nih.gov/pubmed/25843259
689.
Freutel, M.; Scholz, N. B.; Seitz, A. M.; Ignatius, A.; Dürselen, L.
Mechanical properties and morphological analysis of the transitional zone between meniscal body and ligamentous meniscal attachments
J Biomech, 48 (8) :1350-1355
2015
DOI:10.1016/j.jbiomech.2015.03.003
File:http://www.ncbi.nlm.nih.gov/pubmed/25841294
688.
Popov, C.; Burggraf, M.; Kreja, L.; Ignatius, A.; Schieker, M.; Docheva, D.
Mechanical stimulation of human tendon stem/progenitor cells results in upregulation of matrix proteins, integrins and MMPs, and activation of p38 and ERK1/2 kinases
BMC Mol Biol, 16 (1) :6
2015
DOI:10.1186/s12867-015-0036-6
File:http://www.ncbi.nlm.nih.gov/pubmed/25880261
687.
Malandrino, A.; Pozo, J. M.; Castro-Mateos, I.; Frangi, A. F.; Rijsbergen, M. M.; Ito, K.; Wilke, H. J.; Dao, T. T.; Ho Ba Tho, M. C.; Noailly, J.
On the relative relevance of subject-specific geometries and degeneration-specific mechanical properties for the study of cell death in human intervertebral disk models
Front Bioeng Biotechnol, 3 :5
2015
DOI:10.3389/fbioe.2015.00005
File:http://www.ncbi.nlm.nih.gov/pubmed/25717471
686.
Galbusera, F.; Volkheimer, D.; Reitmaier, S.; Berger-Roscher, N.; Kienle, A.; Wilke, H. J.
Pedicle screw loosening: a clinically relevant complication?
Eur Spine J, 24 (5) :1005-16
2015
DOI:10.1007/s00586-015-3768-6
File:http://www.ncbi.nlm.nih.gov/pubmed/25616349
685.
Qin, R.; Schmid, H.; Muenzberg, C.; Maass, U.; Krndija, D.; Adler, G.; Seufferlein, T.; Liedert, A.; Ignatius, A.; Oswald, F.; Eiseler, T.; Wichert, G.
Phosphorylation and turnover of paxillin in focal contacts is controlled by force and defines the dynamic state of the adhesion site
Cytoskeleton (Hoboken), 72 (2) :101-112
2015
DOI:10.1002/cm.21209
File:http://www.ncbi.nlm.nih.gov/pubmed/25620625
684.
Galbusera, F.; Bassani, T.; La Barbera, L.; Ottardi, C.; Schlager, B.; Brayda-Bruno, M.; Villa, T.; Wilke, H. J.
Planning the Surgical Correction of Spinal Deformities: Toward the Identification of the Biomechanical Principles by Means of Numerical Simulation
Front Bioeng Biotechnol, 3 :178
2015
DOI:10.3389/fbioe.2015.00178
File:http://www.ncbi.nlm.nih.gov/pubmed/26579518
683.
Schwarz, S.; Elsaesser, A. F.; Koerber, L.; Goldberg-Bockhorn, E.; Seitz, A. M.; Bermueller, C.; Dürselen, L.; Ignatius, A.; Breiter, R.; Rotter, N.
Processed xenogenic cartilage as innovative biomatrix for cartilage tissue engineering: effects on chondrocyte differentiation and function
J Tissue Eng Regen Med, 9 (12) :E239-E251
2015
DOI:10.1002/term.1650
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682.
Huber-Lang, M.; Ignatius, A.; Brenner, R. E.
Role of Complement on Broken Surfaces After Trauma
Adv Exp Med Biol, 865 :43-55
2015
DOI:10.1007/978-3-319-18603-0_3
File:http://www.ncbi.nlm.nih.gov/pubmed/26306442
681.
Lips, K. S.; Yanko, O.; Kneffel, M.; Panzer, I.; Kauschke, V.; Madzharova, M.; Henss, A.; Schmitz, P.; Rohnke, M.; Bauerle, T.; Liu, Y.; Kampschulte, M.; Langheinrich, A. C.; Dürselen, L.; Ignatius, A.; Heiss, C.; Schnettler, R.; Kilian, O.
Small changes in bone structure of female inverted question mark7 nicotinic acetylcholine receptor knockout mice
BMC Musculoskelet Disord, 16 (1) :5
2015
DOI:10.1186/s12891-015-0459-8
File:http://www.ncbi.nlm.nih.gov/pubmed/25636336
680.
Häussler, K.; Wilke, H. J.
Structural behavior of human lumbar intervertebral disc under direct shear
J Appl Biomater Funct Mater, 13 (1) :e66-e71
2015
DOI:10.5301/jabfm.5000176
File:http://www.ncbi.nlm.nih.gov/pubmed/24744233
679.
Rapp, A. E.; Bindl, R.; Heilmann, A.; Erbacher, A.; Muller, I.; Brenner, R. E.; Ignatius, A.
Systemic mesenchymal stem cell administration enhances bone formation in fracture repair but not load-induced bone formation
Eur Cell Mater, 29 :22-34
2015
File:http://www.ncbi.nlm.nih.gov/pubmed/25552426
678.
Wehrle, E.; Liedert, A.; Heilmann, A.; Wehner, T.; Bindl, R.; Fischer, L.; Haffner-Luntzer, M.; Jakob, F.; Schinke, T.; Amling, M.; Ignatius, A.
The impact of low-magnitude high-frequency vibration on fracture healing is profoundly influenced by the oestrogen status
Dis Model Mech, 8 (1) :93-104
2015
DOI:10.1242/dmm.018622
File:http://www.ncbi.nlm.nih.gov/pubmed/25381012
677.
Ehrnthaller, C.; Flierl, M.; Perl, M.; Denk, S.; Unnewehr, H.; Ward, P. A.; Radermacher, P.; Ignatius, A.; Gebhard, F.; Chinnaiyan, A.; Huber-Lang, M.
The molecular fingerprint of lung inflammation after blunt chest trauma
Eur J Med Res, 20 (1) :70
2015
DOI:10.1186/s40001-015-0164-y
File:http://www.ncbi.nlm.nih.gov/pubmed/26303896

2014

676.
Goldberg-Bockhorn, E.; Schwarz, S.; Elsasser, A.; Seitz, A.; Korber, L.; Dürselen, L.; Ignatius, A.; Feldmann, E. M.; Scheithauer, M.; Breiter, R.; Rotter, N.
[Physical Characterization of Decellularized Cartilage Matrix for Reconstructive Rhinosurgery.]
Laryngorhinootologie, 93 (11) :756-763
2014
DOI:10.1055/s-0034-1384531
File:http://www.ncbi.nlm.nih.gov/pubmed/25369160
675.
Reusch, M.; Wehner, T.; Dürselen, L.; Ignatius, A.
Adaptation of trabecular bone to very high mechanical loads
Osteologie, 23 (3) :202-206
2014
674.
Brayda-Bruno, M.; Tibiletti, M.; Ito, K.; Fairbank, J.; Galbusera, F.; Zerbi, A.; Roberts, S.; Wachtel, E.; Merkher, Y.; Sivan, S. S.
Advances in the diagnosis of degenerated lumbar discs and their possible clinical application
Eur Spine J, 23 (Suppl 3) :S315-S323
2014
DOI:10.1007/s00586-013-2960-9
File:http://www.ncbi.nlm.nih.gov/pubmed/23978994
673.
Galbusera, F.; Rijsbergen, M.; Ito, K.; Huyghe, J. M.; Brayda-Bruno, M.; Wilke, H. J.
Ageing and degenerative changes of the intervertebral disc and their impact on spinal flexibility
Eur Spine J, 23 (Suppl 3) :S324-S332
2014
DOI:10.1007/s00586-014-3203-4
File:http://www.ncbi.nlm.nih.gov/pubmed/24482074
672.
La Barbera, L.; Galbusera, F.; Villa, T.; Costa, F.; Wilke, H. J.
ASTM F1717 standard for the preclinical evaluation of posterior spinal fixators: Can we improve it?
Proc Inst Mech Eng H, 228 (10) :1014-1026
2014
DOI:10.1177/0954411914554244
File:http://www.ncbi.nlm.nih.gov/pubmed/25319550
671.
Govindarajan, P.; Böcker, W.; El Khassawna, T.; Kampschulte, M.; Schlewitz, G.; Huerter, B.; Sommer, U.; Dürselen, L.; Ignatius, A.; Bauer, N. B.; Szalay, G.; Wenisch, S.; Lips, K. S.; Schnettler, R.; Langheinrich, A. C.; Heiss, C.
Bone Matrix, Cellularity, and Structural Changes in a Rat Model with High-Turnover Osteoporosis Induced by Combined Ovariectomy and a Multiple-Deficient Diet
Am J Pathol, 184 (3) :765-777
2014
DOI:10.1016/j.ajpath.2013.11.011
File:http://www.ncbi.nlm.nih.gov/pubmed/24384131
670.
Müller, A.; Schleid, T.; Doser, M.; Müschenborn, N.; Tautzenberger, A.; Ignatius, A; Clauß, B.; Buchmeiser, M.R.
Calcium Cl/OH-Apatite, Cl/OH-Apatite/Al2O3 and Ca3(PO4)2 Fibre Nonwovens: Potential Ceramic Components for Osteosynthesis
J Eur Ceram Soc, 34 (15) :3993-4000
2014
669.
Kregar Velikonja, N.; Urban, J.; Frohlich, M.; Neidlinger-Wilke, C.; Kletsas, D.; Potocar, U.; Turner, S.; Roberts, S.
Cell sources for nucleus pulposus regeneration
Eur Spine J, 23 (Suppl 3) :S364-S374
2014
DOI:10.1007/s00586-013-3106-9
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668.
Käfer, W.; Cakir, B.; Midderhoff, S.; Reichel, H.; Wilke, H. J.
Circumferential dynamic stabilization of the lumbar spine: a biomechanical analysis
Eur Spine J, 23 (11) :2330-2339
2014
DOI:10.1007/s00586-014-3286-y
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667.
Villa, T.; La Barbera, L.; Galbusera, F.
Comparative analysis of international standards for the fatigue testing of posterior spinal fixation systems
Spine J, 14 (4) :695-704
2014
DOI:10.1016/j.spinee.2013.08.032
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Dreischarf, M.; Zander, T.; Shirazi-Adl, A.; Puttlitz, C. M.; Adam, C. J.; Chen, C. S.; Goel, V. K.; Kiapour, A.; Kim, Y. H.; Labus, K. M.; Little, J. P.; Park, W. M.; Wang, Y. H.; Wilke, H. J.; Rohlmann, A.
Comparison of eight published static finite element models of the intact lumbar spine: Predictive power of models improves when combined together
J Biomech, 47 (8) :1757-66
2014
DOI:10.1016/j.jbiomech.2014.04.002
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665.
Galbusera, F.; Bashkuev, M.; Wilke, H. J.; Shirazi-Adl, A.
Comparison of various contact algorithms for poroelastic tissues
Comput Methods Biomech Biomed Engin, 17 (12) :1323-34
2014
DOI:10.1080/10255842.2012.745858
File:http://www.ncbi.nlm.nih.gov/pubmed/23244496

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