Publications

You find here a complete list of publications authored or coauthered by members of our institute since 1974. By default the entire list is presented.

2016

718.
Riegger, J.; Joos, H.; Palm, H. G.; Friemert, B.; Reichel, H.; Ignatius, A.; Brenner, R. E.
Antioxidative therapy in an ex vivo human cartilage trauma-model: Attenuation of trauma-induced cell loss and ECM-destructive enzymes by N-acetyl cysteine
Osteoarthritis Cartilage, 24 (12) :2171-2180
2016
DOI:10.1016/j.joca.2016.07.019
File:http://www.ncbi.nlm.nih.gov/pubmed/27514995
717.
Ehrnthaller, C.; Huber-Lang, M.; Kovtun, A.; Rapp, A. E.; Kemmler, J.; Gebhard, F.; Ignatius, A.
C5aR inhibition in the early inflammatory phase does not affect bone regeneration in a model of uneventful fracture healing
Eur J Med Res, 21 (1) :42
2016
DOI:10.1186/s40001-016-0236-7
File:https://www.ncbi.nlm.nih.gov/pubmed/27784330
716.
Pratsinis, H.; Papadopoulou, A.; Neidlinger-Wilke, C.; Brayda-Bruno, M.; Wilke, H. J.; Kletsas, D.
Cyclic tensile stress of human annulus fibrosus cells induces MAPK activation: involvement in proinflammatory gene expression
Osteoarthritis Cartilage, 24 (4) :679-87
2016
DOI:10.1016/j.joca.2015.11.022
File:http://www.ncbi.nlm.nih.gov/pubmed/26687822
715.
Simon, M. J.; Beil, F. T.; Riedel, C.; Lau, G.; Tomsia, A.; Zimmermann, E. A.; Koehne, T.; Ueblacker, P.; Ruther, W.; Pogoda, P.; Ignatius, A.; Amling, M.; Oheim, R.
Deterioration of teeth and alveolar bone loss due to chronic environmental high-level fluoride and low calcium exposure
Clin Oral Investig, 20 (9) :2361-2370
2016
DOI:10.1007/s00784-016-1727-1
File:http://www.ncbi.nlm.nih.gov/pubmed/26818581
714.
Kienle, A.; Graf, N.; Wilke, H. J.
Does impaction of titanium-coated interbody fusion cages into the disc space cause wear debris and/or delamination?
Spine J, 16 :2
2016
DOI:10.1016/j.spinee.2015.09.038
File:http://www.ncbi.nlm.nih.gov/pubmed/26409208

2015

713.
Qin, R.; Schmid, H.; Muenzberg, C.; Maass, U.; Krndija, D.; Adler, G.; Seufferlein, T.; Liedert, A.; Ignatius, A.; Oswald, F.; Eiseler, T.; Wichert, G.
Phosphorylation and turnover of paxillin in focal contacts is controlled by force and defines the dynamic state of the adhesion site
Cytoskeleton (Hoboken), 72 (2) :101-112
2015
DOI:10.1002/cm.21209
File:http://www.ncbi.nlm.nih.gov/pubmed/25620625
712.
Volkheimer, D.; Malakoutian, M.; Oxland, T. R.; Wilke, H. J.
Limitations of current in vitro test protocols for investigation of instrumented adjacent segment biomechanics: critical analysis of the literature
Eur Spine J, 24 (9) :1882-1892
2015
DOI:10.1007/s00586-015-4040-9
File:http://www.ncbi.nlm.nih.gov/pubmed/26038156
711.
Freutel, M.; Galbusera, F.; Ignatius, A.; Dürselen, L.
Material properties of individual menisci and their attachments obtained through inverse FE-analysis
J Biomech, 48 (8) :1343-1349
2015
DOI:10.1016/j.jbiomech.2015.03.014
File:http://www.ncbi.nlm.nih.gov/pubmed/25843259
710.
Freutel, M.; Scholz, N. B.; Seitz, A. M.; Ignatius, A.; Dürselen, L.
Mechanical properties and morphological analysis of the transitional zone between meniscal body and ligamentous meniscal attachments
J Biomech, 48 (8) :1350-1355
2015
DOI:10.1016/j.jbiomech.2015.03.003
File:http://www.ncbi.nlm.nih.gov/pubmed/25841294
709.
Popov, C.; Burggraf, M.; Kreja, L.; Ignatius, A.; Schieker, M.; Docheva, D.
Mechanical stimulation of human tendon stem/progenitor cells results in upregulation of matrix proteins, integrins and MMPs, and activation of p38 and ERK1/2 kinases
BMC Mol Biol, 16 (1) :6
2015
DOI:10.1186/s12867-015-0036-6
File:http://www.ncbi.nlm.nih.gov/pubmed/25880261
708.
Malandrino, A.; Pozo, J. M.; Castro-Mateos, I.; Frangi, A. F.; Rijsbergen, M. M.; Ito, K.; Wilke, H. J.; Dao, T. T.; Ho Ba Tho, M. C.; Noailly, J.
On the relative relevance of subject-specific geometries and degeneration-specific mechanical properties for the study of cell death in human intervertebral disk models
Front Bioeng Biotechnol, 3 :5
2015
DOI:10.3389/fbioe.2015.00005
File:http://www.ncbi.nlm.nih.gov/pubmed/25717471
707.
Galbusera, F.; Volkheimer, D.; Reitmaier, S.; Berger-Roscher, N.; Kienle, A.; Wilke, H. J.
Pedicle screw loosening: a clinically relevant complication?
Eur Spine J, 24 (5) :1005-16
2015
DOI:10.1007/s00586-015-3768-6
File:http://www.ncbi.nlm.nih.gov/pubmed/25616349
706.
Wehrle, E.; Liedert, A.; Heilmann, A.; Wehner, T.; Bindl, R.; Fischer, L.; Haffner-Luntzer, M.; Jakob, F.; Schinke, T.; Amling, M.; Ignatius, A.
The impact of low-magnitude high-frequency vibration on fracture healing is profoundly influenced by the oestrogen status
Dis Model Mech, 8 (1) :93-104
2015
DOI:10.1242/dmm.018622
File:http://www.ncbi.nlm.nih.gov/pubmed/25381012
705.
Galbusera, F.; Bassani, T.; La Barbera, L.; Ottardi, C.; Schlager, B.; Brayda-Bruno, M.; Villa, T.; Wilke, H. J.
Planning the Surgical Correction of Spinal Deformities: Toward the Identification of the Biomechanical Principles by Means of Numerical Simulation
Front Bioeng Biotechnol, 3 :178
2015
DOI:10.3389/fbioe.2015.00178
File:http://www.ncbi.nlm.nih.gov/pubmed/26579518
704.
Schwarz, S.; Elsaesser, A. F.; Koerber, L.; Goldberg-Bockhorn, E.; Seitz, A. M.; Bermueller, C.; Dürselen, L.; Ignatius, A.; Breiter, R.; Rotter, N.
Processed xenogenic cartilage as innovative biomatrix for cartilage tissue engineering: effects on chondrocyte differentiation and function
J Tissue Eng Regen Med, 9 (12) :E239-E251
2015
DOI:10.1002/term.1650
File:http://www.ncbi.nlm.nih.gov/pubmed/23193064 http://onlinelibrary.wiley.com/doi/10.1002/term.1650/abstract
703.
Huber-Lang, M.; Ignatius, A.; Brenner, R. E.
Role of Complement on Broken Surfaces After Trauma
Adv Exp Med Biol, 865 :43-55
2015
DOI:10.1007/978-3-319-18603-0_3
File:http://www.ncbi.nlm.nih.gov/pubmed/26306442
702.
Lips, K. S.; Yanko, O.; Kneffel, M.; Panzer, I.; Kauschke, V.; Madzharova, M.; Henss, A.; Schmitz, P.; Rohnke, M.; Bauerle, T.; Liu, Y.; Kampschulte, M.; Langheinrich, A. C.; Dürselen, L.; Ignatius, A.; Heiss, C.; Schnettler, R.; Kilian, O.
Small changes in bone structure of female inverted question mark7 nicotinic acetylcholine receptor knockout mice
BMC Musculoskelet Disord, 16 (1) :5
2015
DOI:10.1186/s12891-015-0459-8
File:http://www.ncbi.nlm.nih.gov/pubmed/25636336
701.
Häussler, K.; Wilke, H. J.; Wolfram, U.
Structural behavior of human lumbar intervertebral disc under direct shear
J Appl Biomater Funct Mater, 13 (1) :e66-e71
2015
DOI:10.5301/jabfm.5000176
File:http://www.ncbi.nlm.nih.gov/pubmed/24744233
700.
Rapp, A. E.; Bindl, R.; Heilmann, A.; Erbacher, A.; Muller, I.; Brenner, R. E.; Ignatius, A.
Systemic mesenchymal stem cell administration enhances bone formation in fracture repair but not load-induced bone formation
Eur Cell Mater, 29 :22-34
2015
File:http://www.ncbi.nlm.nih.gov/pubmed/25552426
699.
Ehrnthaller, C.; Flierl, M.; Perl, M.; Denk, S.; Unnewehr, H.; Ward, P. A.; Radermacher, P.; Ignatius, A.; Gebhard, F.; Chinnaiyan, A.; Huber-Lang, M.
The molecular fingerprint of lung inflammation after blunt chest trauma
Eur J Med Res, 20 (1) :70
2015
DOI:10.1186/s40001-015-0164-y
File:http://www.ncbi.nlm.nih.gov/pubmed/26303896
698.
Freutel, M.; Seitz, A. M.; Ignatius, A.; Dürselen, L.
Influence of partial meniscectomy on attachment forces, superficial strain and contact mechanics in porcine knee joints
Knee Surg Sports Traumatol Arthrosc, 23 (1) :74-82
2015
DOI:10.1007/s00167-014-2951-3
File:http://www.ncbi.nlm.nih.gov/pubmed/24671386
697.
Berger-Roscher, N.; Galbusera, F.; Rasche, V.; Wilke, H. J.
Intervertebral disc lesions: visualisation with ultra-high field MRI at 11.7 T
Eur Spine J, 24 (11) :2488-2495
2015
DOI:10.1007/s00586-015-4146-0
File:http://www.ncbi.nlm.nih.gov/pubmed/26206293
696.
Wagner, K.; Asfar, P.; Stahl, B.; Huber-Lang, M.; Ignatius, A.; Duechs, M.; Radermacher, P.; Wagner, F.
Blunt Chest Trauma in Mice after Cigarette Smoke-Exposure: Effects of Mechanical Ventilation with 100 % O2
PLoS One, 10 (7) :e0132810
2015
DOI:10.1371/journal.pone.0132810
File:http://www.ncbi.nlm.nih.gov/pubmed/26225825
695.
Kovtun, A.; Göckelmann, M. J.; Niclas, A. A.; Montufar, E. B.; Ginebra, M. P.; Planell, J. A.; Santin, M.; Ignatius, A.
In vivo performance of novel soybean/gelatin-based bioactive and injectable hydroxyapatite foams
Acta Biomater, 12 :242-9
2015
DOI:10.1016/j.actbio.2014.10.034
File:http://www.ncbi.nlm.nih.gov/pubmed/25448348
694.
Kauschke, V.; Kneffel, M.; Floel, W.; Hartmann, S.; Kampschulte, M.; Dürselen, L.; Ignatius, A.; Schnettler, R.; Heiss, C.; Lips, K. S.
Bone status of acetylcholinesterase-knockout mice
Int Immunopharmacol, 29 (1) :222-230
2015
DOI:10.1016/j.intimp.2015.07.046
File:http://www.ncbi.nlm.nih.gov/pubmed/26250336 http://ac.els-cdn.com/S1567576915300588/1-s2.0-S1567576915300588-main.pdf?_tid=2424816a-7e20-11e5-bb0c-00000aab0f01&acdnat=1446111401_5020b4d28afab4cd2bdd0bdeed30384d http://ac.els-cdn.com/S1567576915300588/1-
693.
Wilke, H. J.
[Biomechanical aspects of vertebral augmentation]
Unfallchirurg, 118 (10) :822-830
2015
DOI:10.1007/s00113-015-0066-z
File:http://www.ncbi.nlm.nih.gov/pubmed/26358323
692.
Gruchenberg, K.; Ignatius, A.; Friemert, B.; Lübken, F.; Skaer, N.; Gellynck, K.; Kessler, O.; Dürselen, L.
In vivo performance of a novel silk fibroin scaffold for partial meniscal replacement in a sheep model
Knee Surg Sports Traumatol Arthrosc, 23 (8) :2218-29
2015
DOI:10.1007/s00167-014-3009-2
File:http://www.ncbi.nlm.nih.gov/pubmed/24770350
690.
Haffner-Luntzer, M.; Liedert, A.; Ignatius, A.
[Mechanobiology and bone metabolism : Clinical relevance for fracture treatment]
Unfallchirurg, 118 (12) :1000-6
2015
DOI:10.1007/s00113-015-0102-z
File:http://www.ncbi.nlm.nih.gov/pubmed/26577661
689.
Lips, K. S.; Kneffel, M.; Willscheid, F.; Mathies, F. M.; Kampschulte, M.; Hartmann, S.; Panzer, I.; Dürselen, L.; Heiss, C.; Kauschke, V.
Altered ultrastructure, density and cathepsin K expression in bone of female muscarinic acetylcholine receptor M3 knockout mice
Int Immunopharmacol, 29 (1) :201-207
2015
DOI:10.1016/j.intimp.2015.05.012
File:http://www.ncbi.nlm.nih.gov/pubmed/26002583 http://ac.els-cdn.com/S1567576915002349/1-s2.0-S1567576915002349-main.pdf?_tid=19c2185e-7e20-11e5-a269-00000aab0f6c&acdnat=1446111384_17d2b5252bc98d5071335b59881e9f6b http://ac.els-cdn.com/S1567576915002349/1-
688.
Rapp, A. E.; Kroner, J.; Baur, S.; Schmid, F.; Walmsley, A.; Mottl, H.; Ignatius, A.
Analgesia via blockade of NGF/TrkA signaling does not influence fracture healing in mice
J Orthop Res, 33 (8) :1235-1241
2015
DOI:10.1002/jor.22892
File:http://www.ncbi.nlm.nih.gov/pubmed/25876530
687.
Sörensen, JH; Dürselen, L; Welch, K; Sörensen, TC; Procter, P; Engqvist, H; Stromme, M; Ignatius, A; Steckel, H
Biomimetic Hydroxyapatite Coated Titanium Screws Demonstrate Rapid Implant Stabilization and Safe Removal In-Vivo
J Biomater Nanobiotechnol, 6 (1) :20-35
2015
DOI:http://dx.doi.org/10.4236/jbnb.2015.61003
686.
Dürselen, L; Freutel, M.
Biomechanik des Meniskus
Orthopädie und Unfallchirurgie up2date, 10 (3) :215-227
2015
685.
Haupt, M.; Kauschke, V.; Sender, J.; Kampschulte, M.; Kovtun, A.; Dürselen, L.; Heiss, C.; Lips, K. S.
Bone status of adult female butyrylcholinesterase gene-deficient mice
Int Immunopharmacol, 29 (1) :208-214
2015
DOI:10.1016/j.intimp.2015.06.029
File:http://www.ncbi.nlm.nih.gov/pubmed/26138460 http://ac.els-cdn.com/S1567576915300059/1-s2.0-S1567576915300059-main.pdf?_tid=14a56452-7e20-11e5-a71f-00000aab0f26&acdnat=1446111375_6a2191e6c0577147b54c8f5410db6527 http://ac.els-cdn.com/S1567576915300059/1-
684.
Steiner, M.; Volkheimer, D.; Meyers, N.; Wehner, T.; Wilke, H. J.; Claes, L.; Ignatius, A.
Comparison between Different Methods for Biomechanical Assessment of Ex Vivo Fracture Callus Stiffness in Small Animal Bone Healing Studies
PLoS One, 10 (3) :e0119603
2015
DOI:10.1371/journal.pone.0119603
File:http://www.ncbi.nlm.nih.gov/pubmed/25781027
683.
El Khassawna, T.; Böcker, W.; Brodsky, K.; Weisweiler, D.; Govindarajan, P.; Kampschulte, M.; Thormann, U.; Henss, A.; Rohnke, M.; Bauer, N.; Müller, R.; Deutsch, A.; Ignatius, A.; Dürselen, L.; Langheinrich, A.; Lips, K. S.; Schnettler, R.; Heiss, C.
Impaired extracellular matrix structure resulting from malnutrition in ovariectomized mature rats
Histochem Cell Biol, 144 (5) :491-507
2015
DOI:10.1007/s00418-015-1356-9
File:http://www.ncbi.nlm.nih.gov/pubmed/26210855
682.
Doyle, H.; Lohfeld, S.; Dürselen, L.; McHugh, P.
Computational modelling of ovine critical-sized tibial defects with implanted scaffolds and prediction of the safety of fixator removal
J Mech Behav Biomed Mater, 44C :133-146
2015
DOI:10.1016/j.jmbbm.2015.01.008
File:http://www.ncbi.nlm.nih.gov/pubmed/25637824
681.
Wilke, H. J.; Mathes, B.; Midderhoff, S.; Graf, N.
Development of a scoliotic spine model for biomechanical in vitro studies
Clin Biomech (Bristol, Avon), 30 (2) :182-187
2015
DOI:10.1016/j.clinbiomech.2014.12.002
File:http://www.ncbi.nlm.nih.gov/pubmed/25533272
680.
Joos, H.; Leucht, F.; Riegger, J.; Hogrefe, C.; Fiedler, J.; Dürselen, L.; Reichel, H.; Ignatius, A.; Brenner, R. E.
Differential Interactive Effects of Cartilage Traumatization and Blood Exposure In Vitro and In Vivo
Am J Sports Med, 43 (11) :2822-32
2015
DOI:10.1177/0363546515602248
File:http://www.ncbi.nlm.nih.gov/pubmed/26362437 http://ajs.sagepub.com/content/early/2015/09/11/0363546515602248.long
679.
Malakoutian, M.; Volkheimer, D.; Street, J.; Dvorak, M. F.; Wilke, H. J.; Oxland, T. R.
Do in vivo kinematic studies provide insight into adjacent segment degeneration? A qualitative systematic literature review
Eur Spine J, 24 (9) :1865-1881
2015
DOI:10.1007/s00586-015-3992-0
File:http://www.ncbi.nlm.nih.gov/pubmed/26055273
678.
Waschke, A.; Berger-Roscher, N.; Kielstein, H.; Ewald, C.; Kalff, R.; Wilke, H. J.
Cement Augmented Anterior Odontoid Screw Fixation is Biomechanically Advantageous in Osteoporotic Patients with Anderson Type II Fractures
J Spinal Disord Tech, 28 (3) :E126-32
2015
DOI:10.1097/BSD.0000000000000177
File:http://www.ncbi.nlm.nih.gov/pubmed/25310397
677.
Kemmler, J.; Bindl, R.; Wagner, F.; Wagner, K.; Radermacher, P.; Ignatius, A.
Exposure to 100% Oxygen Abolishes the Impairment of Fracture Healing after Thoracic Trauma
PLoS One, 10 (7) :e0131194
2015
DOI:10.1371/journal.pone.0131194
File:http://www.ncbi.nlm.nih.gov/pubmed/26147725

2014

676.
Neidlinger-Wilke, C.; Galbusera, F.; Pratsinis, H.; Mavrogonatou, E.; Mietsch, A.; Kletsas, D.; Wilke, H. J.
Mechanical loading of the intervertebral disc: from the macroscopic to the cellular level
Eur Spine J, 23 (Suppl 3) :S333-S343
2014
DOI:10.1007/s00586-013-2855-9
File:http://www.ncbi.nlm.nih.gov/pubmed/23793454
675.
Neidlinger-Wilke, C.; Boldt, A.; Brochhausen, C.; Galbusera, F.; Carstens, C.; Copf, F.; Schultheiß, M.; Lazary, A.; Brayda-Bruno, M.; Ignatius, A.; Wilke, H. J.
Molecular Interactions Between Human Cartilaginous Endplates and Nucleus Pulposus Cells: A Preliminary Investigation
Spine (Phila Pa 1976), 39 (17) :1355-1364
2014
DOI:10.1097/BRS.0000000000000372
File:http://www.ncbi.nlm.nih.gov/pubmed/24831500
674.
Freutel, M.; Seitz, A. M.; Galbusera, F.; Bornstedt, A.; Rasche, V.; Knothe Tate, M. L.; Ignatius, A.; Dürselen, L.
Medial meniscal displacement and strain in three dimensions under compressive loads: MR assessment
J Magn Reson Imaging, 40 :1181-1188
2014
DOI:10.1002/jmri.24461
File:http://www.ncbi.nlm.nih.gov/pubmed/24323799
673.
Galbusera, F.; Brayda-Bruno, M.; Wilke, H. J.
Is post-contrast MRI a valuable method for the study of the nutrition of the intervertebral disc?
J Biomech, 47 (12) :3028-34
2014
DOI:10.1016/j.jbiomech.2014.06.039
File:http://www.ncbi.nlm.nih.gov/pubmed/25059896
672.
Galbusera, F.; Freutel, M.; Dürselen, L.; D'Aiuto, M.; Croce, D.; Villa, T.; Sansone, V.; Innocenti, B.
Material Models and Properties in the Finite Element Analysis of Knee Ligaments: A Literature Review
Front Bioeng Biotechnol, 2 :54
2014
DOI:10.3389/fbioe.2014.00054
File:http://www.ncbi.nlm.nih.gov/pubmed/25478560
671.
Oheim, R.; Beil, F. T.; Krause, M.; Bindl, R.; Ignatius, A.; Pogoda, P.
Mandibular bone loss in ewe induced by hypothalamic-pituitary disconnection
Clin Oral Implants Res, 25 (11) :1239-44
2014
DOI:10.1111/clr.12259
File:http://www.ncbi.nlm.nih.gov/pubmed/24102843
670.
Matzaroglou, C.; Georgiou, C. S.; Panagopoulos, A.; Assimakopoulos, K.; Wilke, H. J.; Habermann, B.; Panos, G.; Kafchitsas, K.
Kummell's Disease: Clarifying the Mechanisms and Patients' Inclusion Criteria
Open Orthop J, 8 :288-97
2014
DOI:10.2174/1874325001408010288
File:http://www.ncbi.nlm.nih.gov/pubmed/25246995
669.
Steiner, M.; Claes, L.; Ignatius, A.; Simon, U.; Wehner, T.
Numerical Simulation of Callus Healing for Optimization of Fracture Fixation Stiffness
PLoS One, 9 (7) :e101370
2014
DOI:10.1371/journal.pone.0101370
File:http://www.ncbi.nlm.nih.gov/pubmed/24991809
668.
Galbusera, F.; Tibiletti, M.; Brayda-Bruno, M.; Neidlinger-Wilke, C.; Wilke, H. J.
Inverse numerical prediction of the transport properties of vertebral endplates in low back pain patients
Biomed Tech (Berl), 59 (5) :385–397
2014
DOI:10.1515/bmt-2013-0122
File:http://www.ncbi.nlm.nih.gov/pubmed/24633746
667.
Galbusera, F.; Brayda-Bruno, M.; Costa, F.; Wilke, H. J.
Numerical evaluation of the correlation between the normal variation in the sagittal alignment of the lumbar spine and the spinal loads
J Orthop Res, 32 (4) :537-544
2014
DOI:10.1002/jor.22569
File:http://www.ncbi.nlm.nih.gov/pubmed/24375659
666.
Qi, Y.; Jiang, D.; Sindrilaru, A.; Stegemann, A.; Schatz, S.; Treiber, N.; Rojewski, M.; Schrezenmeier, H.; Beken, S. V.; Wlaschek, M.; Bohm, M.; Seitz, A.; Scholz, N.; Dürselen, L.; Brinckmann, J.; Ignatius, A.; Scharffetter-Kochanek, K.
TSG-6 Released from Intradermally Injected Mesenchymal Stem Cells Accelerates Wound Healing and Reduces Tissue Fibrosis in Murine Full-Thickness Skin Wounds
J Invest Dermatol, 134 (2) :526-537
2014
DOI:10.1038/jid.2013.328
File:http://www.ncbi.nlm.nih.gov/pubmed/23921952
665.
Leyh, M.; Seitz, A.; Dürselen, L.; Springorum, H. R.; Angele, P.; Ignatius, A.; Grifka, J.; Grässel, S.
Osteoarthritic cartilage explants affect extracellular matrix production and composition in cocultured bone marrow-derived mesenchymal stem cells and articular chondrocytes
Stem Cell Res Ther, 5 (3) :77
2014
DOI:10.1186/scrt466
File:http://www.ncbi.nlm.nih.gov/pubmed/24916039
664.
Liedert, A.; Röntgen, V.; Schinke, T.; Benisch, P.; Ebert, R.; Jakob, F.; Klein-Hitpass, L.; Lennerz, J. K.; Amling, M.; Ignatius, A.
Osteoblast-Specific Krm2 Overexpression and Lrp5 Deficiency Have Different Effects on Fracture Healing in Mice
PLoS One, 9 (7) :e103250
2014
DOI:10.1371/journal.pone.0103250
File:http://www.ncbi.nlm.nih.gov/pubmed/25061805
663.
Werz, T.; Baumann, M.; Wolfram, U.; Krill, C. E.
Particle tracking during Ostwald ripening using time-resolved laboratory X-ray microtomography
Materials Characterization, 90 :185-195
2014
DOI:10.1016/j.matchar.2014.01.022
File:
662.
Wehner, T.; Steiner, M.; Ignatius, A.; Claes, L.
Prediction of the time course of callus stiffness as a function of mechanical parameters in experimental rat fracture healing studies - a numerical study
PLoS One, 9 (12) :e115695
2014
DOI:10.1371/journal.pone.0115695
File:http://www.ncbi.nlm.nih.gov/pubmed/25532060

2014

661.
Böcker, W.; El Khassawna, T.; Bauer, N.; Brodsky, K.; Weisweiler, D.; Govindarajan, P.; Schlewitz, G.; Kampschulte, M.; Dürselen, L.; Thormann, U.; Szalay, G.; Schnettler, R.; Langheinrich, A. C.; Heiss, C.
Short-term glucocorticoid treatment causes spinal osteoporosis in ovariectomized rats
Eur Spine J, 23 (11) :2437-2448
2014
DOI:10.1007/s00586-014-3463-z
File:http://www.ncbi.nlm.nih.gov/pubmed/25077942

2014

660.
Leyh, M.; Seitz, A.; Dürselen, L.; Schaumburger, J.; Ignatius, A.; Grifka, J.; Grässel, S.
Subchondral bone influences chondrogenic differentiation and collagen production of human bone marrow-derived mesenchymal stem cells and articular chondrocytes
Arthritis Res Ther, 16 (5) :453
2014
DOI:10.1186/s13075-014-0453-9
File:http://www.ncbi.nlm.nih.gov/pubmed/25296561
659.
Wehner, T.; Gruchenberg, K.; Bindl, R.; Recknagel, S.; Steiner, M.; Ignatius, A.; Claes, L.
Temporal delimitation of the healing phases via monitoring of fracture callus stiffness in rats
J Orthop Res, 32 (12) :1589–1595
2014
DOI:10.1002/jor.22721
File:http://www.ncbi.nlm.nih.gov/pubmed/25183200
658.
Nelitz, M.; Wehner, T.; Steiner, M.; Dürselen, L.; Lippacher, S.
The effects of femoral external derotational osteotomy on frontal plane alignment
Knee Surg Sports Traumatol Arthrosc, 22 (11) :2740-2746
2014
DOI:10.1007/s00167-013-2618-5
File:http://www.ncbi.nlm.nih.gov/pubmed/23887859
657.
Liedert, A.; Schinke, T.; Ignatius, A.; Amling, M.
The Role of Midkine in Skeletal Remodeling
Br J Pharmacol, 171 (4) :870-8
2014
DOI:10.1111/bph.12412
File:http://www.ncbi.nlm.nih.gov/pubmed/24102259
656.
Claes, L.
Ultraschall als Therapieansatz zur Beschleunigung der Frakturheilung
Orthopädie und Unfallchirurgie up2date, 9 (5) :427-436
2014
655.
Schwen, L. O.; Wolfram, U.
Validation of composite finite elements efficiently simulating elasticity of trabecular bone
Comput Methods Biomech Biomed Engin, 17 (6) :652-60
2014
DOI:10.1080/10255842.2012.714373
File:http://www.ncbi.nlm.nih.gov/pubmed/23025631
654.
Reitmaier, S.; Kreja, L.; Gruchenberg, K.; Kanter, B.; Silva-Correia, J.; Oliveira, J. M.; Reis, R. L.; Perugini, V.; Santin, M.; Ignatius, A.; Wilke, H. J.
In vivo biofunctional evaluation of hydrogels for disc regeneration
Eur Spine J, 23 (1) :19-26
2014
DOI:10.1007/s00586-013-2998-8
File:http://www.ncbi.nlm.nih.gov/pubmed/24121748
653.
Reitmaier, S.; Volkheimer, D.; Berger-Roscher, N.; Wilke, H. J.; Ignatius, A.
Increase or decrease in stability after nucleotomy? Conflicting in vitro and in vivo results in the sheep model
J R Soc Interface, 11 (100)
2014
DOI:10.1098/rsif.2014.0650
File:http://www.ncbi.nlm.nih.gov/pubmed/25209401
652.
Haffner-Luntzer, M.; Heilmann, A.; Rapp, A.; Beie, S.; Schinke, T.; Amling, M.; Ignatius, A; Liedert, A.
Midkine Deficiency Delays Chondrogenesis during the Early Phase of Fracture Healing in Mice
PLoS One, 9 (12) :e116282
2014
File:pdfhttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC4281158/pdf/pone.0116282.pdf
651.
Ewert, Katrin; Wilke, H. J.
In der Bandscheibenwerkstatt
Focus Gesundheit, Der Rücken, 21 :80-85
2014
650.
Galbusera, F.; Bashkuev, M.; Wilke, H. J.; Shirazi-Adl, A.
Comparison of various contact algorithms for poroelastic tissues
Comput Methods Biomech Biomed Engin, 17 (12) :1323-34
2014
DOI:10.1080/10255842.2012.745858
File:http://www.ncbi.nlm.nih.gov/pubmed/23244496
649.
Goldberg-Bockhorn, E.; Schwarz, S.; Elsasser, A.; Seitz, A.; Korber, L.; Dürselen, L.; Ignatius, A.; Feldmann, E. M.; Scheithauer, M.; Breiter, R.; Rotter, N.
[Physical Characterization of Decellularized Cartilage Matrix for Reconstructive Rhinosurgery.]
Laryngorhinootologie, 93 (11) :756-763
2014
DOI:10.1055/s-0034-1384531
File:http://www.ncbi.nlm.nih.gov/pubmed/25369160
648.
Wölfle, J. V.; Fiedler, J.; Dürselen, L.; Reichert, J.; Scharnweber, D.; Forster, A.; Schwenzer, B.; Reichel, H.; Ignatius, A.; Brenner, R. E.
Improved Anchorage of Ti6Al4V Orthopaedic Bone Implants through Oligonucleotide Mediated Immobilization of BMP-2 in Osteoporotic Rats
PLoS One, 9 (1) :e86151
2014
DOI:10.1371/journal.pone.0086151
File:http://www.ncbi.nlm.nih.gov/pubmed/24465929
647.
Claes, L.; Reusch, M.; Wehner, T.; Dürselen, L.; Ignatius, A.
Adaptation of trabecular bone to very high mechanical loads
Osteologie, 23 (3) :202-206
2014
646.
Brayda-Bruno, M.; Tibiletti, M.; Ito, K.; Fairbank, J.; Galbusera, F.; Zerbi, A.; Roberts, S.; Wachtel, E.; Merkher, Y.; Sivan, S. S.
Advances in the diagnosis of degenerated lumbar discs and their possible clinical application
Eur Spine J, 23 (Suppl 3) :S315-S323
2014
DOI:10.1007/s00586-013-2960-9
File:http://www.ncbi.nlm.nih.gov/pubmed/23978994
645.
Galbusera, F.; Rijsbergen, M.; Ito, K.; Huyghe, J. M.; Brayda-Bruno, M.; Wilke, H. J.
Ageing and degenerative changes of the intervertebral disc and their impact on spinal flexibility
Eur Spine J, 23 (Suppl 3) :S324-S332
2014
DOI:10.1007/s00586-014-3203-4
File:http://www.ncbi.nlm.nih.gov/pubmed/24482074
644.
Govindarajan, P.; Böcker, W.; El Khassawna, T.; Kampschulte, M.; Schlewitz, G.; Huerter, B.; Sommer, U.; Dürselen, L.; Ignatius, A.; Bauer, N. B.; Szalay, G.; Wenisch, S.; Lips, K. S.; Schnettler, R.; Langheinrich, A. C.; Heiss, C.
Bone Matrix, Cellularity, and Structural Changes in a Rat Model with High-Turnover Osteoporosis Induced by Combined Ovariectomy and a Multiple-Deficient Diet
Am J Pathol, 184 (3) :765-777
2014
DOI:10.1016/j.ajpath.2013.11.011
File:http://www.ncbi.nlm.nih.gov/pubmed/24384131

2014

643.
Müller, A.; Schleid, T.; Doser, M.; Müschenborn, N.; Tautzenberger, A.; Ignatius, A; Clauß, B.; Buchmeiser, M.R.
Calcium Cl/OH-Apatite, Cl/OH-Apatite/Al2O3 and Ca3(PO4)2 Fibre Nonwovens: Potential Ceramic Components for Osteosynthesis
J Eur Ceram Soc, 34 (15) :3993-4000
2014

2014

642.
Kregar Velikonja, N.; Urban, J.; Frohlich, M.; Neidlinger-Wilke, C.; Kletsas, D.; Potocar, U.; Turner, S.; Roberts, S.
Cell sources for nucleus pulposus regeneration
Eur Spine J, 23 (Suppl 3) :S364-S374
2014
DOI:10.1007/s00586-013-3106-9
File:http://www.ncbi.nlm.nih.gov/pubmed/24297331
641.
Käfer, W.; Cakir, B.; Midderhoff, S.; Reichel, H.; Wilke, H. J.
Circumferential dynamic stabilization of the lumbar spine: a biomechanical analysis
Eur Spine J, 23 (11) :2330-2339
2014
DOI:10.1007/s00586-014-3286-y
File:http://www.ncbi.nlm.nih.gov/pubmed/24722881
640.
Villa, T.; La Barbera, L.; Galbusera, F.
Comparative analysis of international standards for the fatigue testing of posterior spinal fixation systems
Spine J, 14 (4) :695-704
2014
DOI:10.1016/j.spinee.2013.08.032
File:http://www.ncbi.nlm.nih.gov/pubmed/24268390
639.
Dreischarf, M.; Zander, T.; Shirazi-Adl, A.; Puttlitz, C. M.; Adam, C. J.; Chen, C. S.; Goel, V. K.; Kiapour, A.; Kim, Y. H.; Labus, K. M.; Little, J. P.; Park, W. M.; Wang, Y. H.; Wilke, H. J.; Rohlmann, A.
Comparison of eight published static finite element models of the intact lumbar spine: Predictive power of models improves when combined together
J Biomech, 47 (8) :1757-66
2014
DOI:10.1016/j.jbiomech.2014.04.002
File:http://www.ncbi.nlm.nih.gov/pubmed/24767702
638.
La Barbera, L.; Galbusera, F.; Villa, T.; Costa, F.; Wilke, H. J.
ASTM F1717 standard for the preclinical evaluation of posterior spinal fixators: Can we improve it?
Proc Inst Mech Eng H, 228 (10) :1014-1026
2014
DOI:10.1177/0954411914554244
File:http://www.ncbi.nlm.nih.gov/pubmed/25319550
637.
Kanter, B.; Geffers, M.; Ignatius, A.; Gbureck, U.
Control of in vivo mineral bone cement degradation
Acta Biomater, 10 (7) :3279-87
2014
DOI:10.1016/j.actbio.2014.04.020
File:http://www.ncbi.nlm.nih.gov/pubmed/24769112
636.
Galbusera, F.; Taschieri, S.; Tsesis, I.; Francetti, L.; Del Fabbro, M.
Finite element simulation of implant placement following extraction of a single tooth
J Appl Biomater Funct Mater, 12 (2) :e84-9
2014
DOI:10.5301/JABFM.5000178
File:http://www.ncbi.nlm.nih.gov/pubmed/24425378
635.
Röderer, G.; Gebhard, F.; Dürselen, L.; Ignatius, A.; Claes, L.
Delayed bone healing following high tibial osteotomy related to increased implant stiffness in locked plating
Injury, 45 (10) :1648-1652
2014
DOI:10.1016/j.injury.2014.04.018
File:http://www.ncbi.nlm.nih.gov/pubmed/24813098
634.
Simon, M. J.; Beil, F. T.; Ruther, W.; Busse, B.; Koehne, T.; Steiner, M.; Pogoda, P.; Ignatius, A.; Amling, M.; Oheim, R.
High fluoride and low calcium levels in drinking water is associated with low bone mass, reduced bone quality and fragility fractures in sheep
Osteoporos Int, 25 (7) :1891-903
2014
DOI:10.1007/s00198-014-2707-4
File:http://www.ncbi.nlm.nih.gov/pubmed/24777741
633.
Radermacher, P.; Volani, C.; Asfar, P.; Ignatius, A.; Kemmler, J.; Wood, M. E.; Wachter, U.
H2S during circulatory shock: Some unresolved questions
Nitric Oxide, 41 :48-61
2014
DOI:10.1016/j.niox.2014.03.163
File:http://www.ncbi.nlm.nih.gov/pubmed/24650697
632.
Büttner-Janz, K.; Meyer, B.; Sambale, R.; Wilke, H. J.; Rüdiger, N.; Büttner, E.
FRISBEE - The First Artificial Cervical Disc of 3rd Generation
Coluna, 13 (1) :43-8
2014
631.
Bashkuev, M.; Galbusera, F.; Wilke, H. J.; Shirazi-Adl, A.
Finite element study of human lumbar disc nucleus replacements
Comput Methods Biomech Biomed Engin, 17 (16) :1762-76
2014
DOI:10.1080/10255842.2013.766722
File:http://www.ncbi.nlm.nih.gov/pubmed/23477684
630.
Freutel, M.; Dürselen, L.; Ignatius, A.; Galbusera, F.
Finite element modeling of soft tissues: Material models, tissue interaction and challenges
Clin Biomech (Bristol, Avon), 29 (4) :363-372
2014
DOI:10.1016/j.clinbiomech.2014.01.006
File:http://www.ncbi.nlm.nih.gov/pubmed/24529470
629.
Wehrle, E.; Wehner, T.; Heilmann, A.; Bindl, R.; Claes, L.; Jakob, F.; Amling, M.; Ignatius, A.
Distinct frequency dependent effects of whole-body vibration on non-fractured bone and fracture healing in mice
J Orthop Res, 32 (8) :1006-1013
2014
DOI:10.1002/jor.22629
File:http://www.ncbi.nlm.nih.gov/pubmed/24729351
628.
Steiner, M.; Claes, L.; Ignatius, A.; Simon, U.; Wehner, T.
Disadvantages of interfragmentary shear on fracture healing-mechanical insights through numerical simulation
J Orthop Res, 32 (7) :865-72
2014
DOI:10.1002/jor.22617
File:http://www.ncbi.nlm.nih.gov/pubmed/24648331
627.
Thormann, U.; Khawassna, T. E.; Ray, S.; Dürselen, L.; Kampschulte, M.; Lips, K. S.; Dewitz, H.; Heinemann, S.; Heiss, C.; Szalay, G.; Langheinrich, A. C.; Ignatius, A.; Schnettler, R.; Alt, V.
Differences of bone healing in metaphyseal defect fractures between osteoporotic and physiological bone in rats
Injury, 45 (3) :487-493
2014
DOI:10.1016/j.injury.2013.10.033
File:http://www.ncbi.nlm.nih.gov/pubmed/24332464
626.
Gumpert, R.; Bodo, K.; Spuller, E.; Poglitsch, T.; Bindl, R.; Ignatius, A.; Puchwein, P.
Demineralization after balloon kyphoplasty with calcium phosphate cement: a histological evaluation in ten patients
Eur Spine J, 23 (6) :1361-8
2014
DOI:10.1007/s00586-014-3239-5
File:http://www.ncbi.nlm.nih.gov/pubmed/24566944

2013

625.
Liedert, A.; Ignatius, A.
Local detection of mechanically induced ATP release from bone cells with ATP microbiosensors
Biosens Bioelectron, 44C :27-33
2013
DOI:10.1016/j.bios.2013.01.008
File:http://www.ncbi.nlm.nih.gov/pubmed/23384767
624.
Garcia, P.; Histing, T.; Holstein, J. H.; Klein, M.; Laschke, M. W.; Matthys, R.; Ignatius, A.; Wildemann, B.; Lienau, J.; Peters, A.; Willie, B.; Duda, G.; Claes, L.; Pohlemann, T.; Menger, M. D.
Rodent animal models of delayed bone healing and non-union formation: a comprehensive review
Eur Cell Mater, 26 :1-14
2013
File:http://www.ncbi.nlm.nih.gov/pubmed/23857280
623.
Bindl, R.; Oheim, R.; Pogoda, P.; Beil, F. T.; Gruchenberg, K.; Reitmaier, S.; Wehner, T.; Radermacher, P.; Claes, L.; Amling, M.; Ignatius, A.
Metaphyseal fracture healing in a sheep model of low turnover osteoporosis induced by hypothalamic-pituitary disconnection (HPD)
J Orthop Res, 31 (11) :1851-1857
2013
DOI:10.1002/jor.22416
File:http://www.ncbi.nlm.nih.gov/pubmed/23813786
622.
Brown, J.; Sandmann, A.; Ignatius, A.; Amling, M.; Barvencik, F.
New perspectives on vitamin D food fortification based on a modeling of 25(OH)D concentrations
Nutr J, 12 (1) :1-12
2013
DOI:10.1186/1475-2891-12-151
File:http://www.ncbi.nlm.nih.gov/pubmed/24261676
621.
Brown, J.; Ignatius, A.; Amling, M.; Barvencik, F.
New perspectives on vitamin D sources in Germany based on a novel mathematical bottom-up model of 25(OH)D serum concentrations
Eur J Nutr, 52 (7) :1733-1742
2013
DOI:10.1007/s00394-012-0477-3
File:http://www.ncbi.nlm.nih.gov/pubmed/23229408
620.
Steiner, M.; Claes, L.; Ignatius, A.; Niemeyer, F.; Simon, U.; Wehner, T.
Prediction of fracture healing under axial loading, shear loading and bending is possible using distortional and dilatational strains as determining mechanical stimuli
J R Soc Interface, 10 (86) :20130389
2013
DOI:10.1098/rsif.2013.0389
File:http://www.ncbi.nlm.nih.gov/pubmed/23825112
619.
Reitmaier, S.; Ihler, R.; Kocak, T.; Graf, N.; Ignatius, A.; Wilke, H. J.
Preliminary Investigations on Intradiscal Pressures during Daily Activities: An In Vivo Study Using the Merino Sheep
PLoS One, 8 (7) :e69610
2013
DOI:10.1371/journal.pone.0069610
File:http://www.ncbi.nlm.nih.gov/pubmed/23894509

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