Institute of Comparative Molecular Endocrinology

The Institute of Comparative Molecular Endocrinology is the only zoological institute with an endocrinological focus in Germany to investigate the hormonal control mechanisms in stress, environmental and aging-related diseases with a focus on the immune system,metabolism and bone integrity, the and modification of the function of RAS GTPases.

As part of the teaching of the Department of Biology (Natural Science Faculty) and the Faculty of Medicine, we impart basic knowledge of molecular and cell biology as well as physiology and endocrinology and introduce students to current research issues.


Glucocorticoids suppress inflammation via mitochondrial rewiring


We are very pleased to announce our recent cooperative nature article with the Krönke lab about glucocorticoid effects in immune metabolism, thanks to Jean-Philipp, Max, Maria, Ulrich, Eicke, Jörg, Georg, Gerhard and many more excellent collaborators! Check out at 

New publication in Nature Metabolism:

GR in macrophages protects from high fat Diet induced Insulin Resistance!

Nature Communications 2023 Apr 2014(1):2271.  doi: 10.1038/s41467-023-37831-z (Link:

FEBS Letters

New Nutshell Review from Stifel et al. made it to the Cover of FEBS Letters: Novel insights into the regulation of cellular catabolic metabolism in macrophages through nuclear receptors. 596, Pages: 2617-262 

The oncogene RAS is often found in non-small cell lung tumors or other types of cancer. This "cancer gene" fuels tumor growth and, until now, could not be specifically switched off. However, researchers at the University of Ulm have now discovered a new function of the so-called glucocorticoid receptor: In interaction with RAS proteins on the cytoplasmic side of the cell membrane, the receptor can slow down tumor growth. The road to concrete therapeutic approaches is still long, but the study has already made it onto the cover of the scientific journal "Science Signaling".



Prof. Dr. Jan Tuckermann
Phone: +49 731 50 32600
Fax: +49 731 50 32609
Helmholtzstr. 8/1
Room: 3.34

follow on Twitter @JanTuckermann

Student office hours:
every tuesday from
04:00 pm - 05:00 pm

Vice Director

Photo Deputy Director Prof. PD Maja Vujic´Spasic´, PhD


Sybille Smith
Phone: +49 731 50 32601
Fax.: +49 731 50 32609
Helmholtzstr. 8/1
Room: 3.33

E-Mail: institut.cme(at)

Student office hours:
Tuesday and Thursday
09:00 am - 12:00 pm and 02:00 pm - 04:00 pm


Ulm University 
Institute of Comparative Molecular Endocrinology
Helmholtzstrasse 8/1
89081 Ulm


Photo Entrance Area Centre for Biomedical Research