Research

The Institute of Comparative Molecular Endocrinology is devoted to basic research unravelling mechanisms of the hormonal control of stress-, ageing and life style related disorders. In our ageing society immune-metabolic disorders, and muskulo-skeletal impairments evolve to a general health problem. The action of hormones of the stress axis, and regulators of mineral homeostasis modulate the underlying multiple organ cross-talk in multiple physiological processes. A precise understanding of hormonal control in animal and human (patho-)physiology provides insight into fundamental biological processes, but also gives rationales for novel treatment options for general immune-metabolic and skeletal diseases.

The Institute hosts the following Research Groups:

Photo Prof. Dr. Jan Tuckermann

Prof. Dr. Jan Tuckermann

Stress associated glucocorticoid hormones in immune system and bone integrity

Dr. Sabine Vettorazzi

Hormonal regulation and novel mechanism for the resolution of inflammation

Associated Research Group Cirstea

Photo Dr. Ion Cristian Cirstea

Dr. Ion Cristian Cirstea

Aging-related and hormonal dependent changes of the expression and activation of RAS GTPases and their downstream signaling pathways

Photo Prof. PD Maja Vujic´Spasic´, PhD

Prof. PD Maja Vujić Spasić, PhD

Hormonal regulation of iron homeostasis

Scientists of the Institute of Comparative Molecular Endocrinology are part of the Collaborative Research Center 1149 „Danger Response, Disturbance Factors and Regenerative Potential after Acute Trauma“. In the following video they are presenting their work on their project „Molecular mechanisms of glucocorticoid action during fracture healing after severe trauma“ (Projekt C2).

Video Project C02 Trauma SFB 1149