Prof. Dr. Jan Tuckermann
Stress associated glucocorticoid hormones in immune system and bone integrity
Research
The Institute of Comparative Molecular Endocrinology is devoted to basic research unravelling mechanisms of the hormonal control of stress-, ageing and life style related disorders. In our ageing society immune-metabolic disorders, and muskulo-skeletal impairments evolve to a general health problem. The action of hormones of the stress axis, and regulators of mineral homeostasis modulate the underlying multiple organ cross-talk in multiple physiological processes. A precise understanding of hormonal control in animal and human (patho-)physiology provides insight into fundamental biological processes, but also gives rationales for novel treatment options for general immune-metabolic and skeletal diseases.
The Institute hosts the following Research Groups:
Dr. Sabine Vettorazzi
Hormonal regulation and novel mechanism for the resolution of inflammation
Associated Research Group Cirstea
Dr. Ion Cristian Cirstea
Aging-related and hormonal dependent changes of the expression and activation of RAS GTPases and their downstream signaling pathways
Prof. PD Maja Vujić Spasić, PhD
Hormonal regulation of iron homeostasis
Dr. Sooyeon Lee
Endocrine Hormonal Regulation in Bone Homeostasis and Regeneration
Scientists of the Institute of Comparative Molecular Endocrinology are part of the Collaborative Research Center 1149 „Danger Response, Disturbance Factors and Regenerative Potential after Acute Trauma“. In the following video they are presenting their work on their project „Molecular mechanisms of glucocorticoid action during fracture healing after severe trauma“ (Projekt C2).