Rosenau lab


Kissmann, A.K., Bolotnikov, G., Li, R., Müller, F., Xing, H., Krämer,·M., Gottschalk, K.-E., Andersson, J., Weil, T., Rosenau, F. (2024). IMPATIENT‑qPCR: monitoring SELEX success during in vitro aptamer evolution.
Applied Microbiology and Biotechnology  108:284

Zhang, Y., Xing, H., Bolotnikov, G., Krämer, M., Bozdogan, A., Kissmann, A.K., Weil, T., Spellerberg, B., Stenger, S., Rosenau, F. (2024). Robust Fluorometric Aptamer Assay for Direct and Rapid Detection of Clinical Isolates of Candida spec. 
Int. J. Mol. Sci. 2024, 25, 3444. Doi: 10.3390/ijms25063444

Vélez, N., Argel, A., Kissmann, A.K,, Alpízar-Pedraza, D., Escandon, P., Rosenau, F., Staendker, L., Firacative ,C. (2024). Pore-forming peptide C14R exhibits potent antifungal activity against clinical isolates of Candida albicans and Candida auris .
Front. Cell. Infect. Microbiol., 14, doi: 10.3389/fcimb.2024.1389020.

Kissmann, A.K., Paß, F., Ruzicka, H.M., Dorst, I., Stieger, K.R., Weil, T., Gihring, A., Elad, L., Knippschild, U., Rosenau, F. (2024). An Increase in Prominent Probiotics Represents the Major Change in the Gut Microbiota in Morbidly Obese Female Patients upon Bariatric Surgery.
Women, 4(1), 86-104.

Widberger, J., Wittgens, A., Klaunig, S., Krämer, M., Kissmann, A.K., Höfele, F., Baur, T., Weil, T., Henkel, M., Hausmann, R., Bengelsdorf, F.R., Eikmanns, B.J., Dürre, P., Rosenau, F. (2024). Recombinant Production of Pseudomonas aeruginosa Rhamnolipids in P. putida KT2440 on Acetobacterium woodii Cultures Grown Chemo-Autotrophically with Carbon Dioxide and Hydrogen.
Microorganisms, 12, 529. doi: 10.3390/microorganisms12030529.

Alpízar-Pedraza, D., Roque-Diaz, Y., Garay-Pérez, H., Rosenau, F., Ständker, L., Montero-Alejo, V. (2024). Insights into the Adsorption Mechanisms of the Antimicrobial Peptide CIDEM-501 on Membrane Models.
Antibiotics 8;13(2),167. doi: 10.3390/antibiotics13020167.

Çetinkaya, A., Kissmann, A.K., Lipinska, M., Trzaskowska, M., Duniec, J., Katariya, H., Slouf, M., Herberger, T., Weil, T., Przekora, A., Rosenau, F., Pietrasik, J. (2024). Oligo(ethylene glycol) methyl ether methacrylate based hydrogel with intrinsic antibacterial activity against Pseudomonas aeruginosa as a model of a major wound infecting human pathogen.
European Polymer Journal,  205, DOI: 10.1016/j.eurpolymj.2024.112758.

Mildenberger, V., Alpízar-Pedraza, D., Martell-Huguet, E.M., Krämer, M., Bolotnikov, G., Otero-Gonzalez, A.J., Weil, T., Rodriguez-Alfonso, A., Preising, N., Ständker, L., Vogel, V., Spellerberg, B., Kissmann, A.K., Rosenau, F. (2024). The Designed Pore-Forming Antimicrobial Peptide C14R Combines Excellent Activity against the Major Opportunistic Human Pathogen Pseudomonas aeruginosa with Low Cytotoxicity.
Pharmaceuticals 17(1), 83. doi: 10.3390/ph17010083.


Zhang, Y., Xing, H., Bolotnikov, G., Krämer, M., Gotzmann, N., Knippschild, U., Kissmann, A.K., Rosenau, F. (2023). Enriched Aptamer Libraries in Fluorescence-Based Assays for Rikenella microfusus-Specific Gut Microbiome Analyses.
Microorganisms,11(9), 2266. doi: 10.3390/microorganisms11092266.

Schuster ,P.A. Uhl, M., Kissmann, A.K, Jansen, F., Geng,T., Ceblin, M.U., Spiewok, S, Rosenau, F.,   Jacob,T., Alexander J. C. Kuehne, J.C. (2023). Conjugated Polyimidazole Nanoparticles as Biodegradable Electrode Materials for Organic Batteries.
Advanced Electron Materials, DOI: 10.1002/aelm.202300464.

Amann, V., Kissmann, A.K., Mildenberger, V., Krebs, I., Perez-Erviti, J.A., Martell-Huguet, E.M., Otero-Gonzalez, A.J., Morales-Vicente, F., Rodríguez-Castaño, G.P., Firacative, C., Rodríguez, A., Ständker, L., Weil, T., Spellerberg, B., Stenger, S., Rosenau, F (2023). Cm-p5 Peptide Dimers Inhibit Biofilms of Candida albicans Clinical Isolates, C. parapsilosis and Fluconazole-Resistant Mutants of C. auris.
Int J Mol Sci. 24(12), 9788. doi: 10.3390/ijms24129788.

Sihler, S., Krämer, M., Schmitt, F., Favella, P., Mützel, L., Baatz, J., Rosenau, F., Ziener, U. (2023). Robust Protocol for the Synthesis of BSA Nanohydrogels by Inverse Nanoemulsion for Drug Delivery.
Langmuir, 39(23), 8176-8185. doi: 10.1021/acs.langmuir.3c00635

Kissmann, A.K., Rosenau, F., Herwig, A., Diedrich, V. (2023) Short Photoperiod-Dependent Enrichment of Akkermansia spec. as the Major Change in the Intestinal Microbiome of Djungarian Hamsters (Phodopus sungorus).
Int J Mol Sci. 24(7), 6605. doi: 10.3390/ijms24076605.

Rodríguez-Castaño, G.P., Rosenau, F., Ständker, L., Firacative, C.(2023). Antimicrobial Peptides: Avant-Garde Antifungal Agents to Fight against Medically Important Candida Species.
Pharmaceutics15(3),789, doi: 10.3390/pharmaceutics15030789.

Kraemer, M., Bellion, M., Kissmann, A.K., Herberger, T, Synatschke, C.V., Bozdogan, A., Andersson,J, Rodriguez, A., Ständker. L., Wiese, S., Stenger, S., Spellerberg, B., Gottschalk, K.E., Cetinkaya, A, Pietrasik, J., Weil, T., Rosenau, F. (2023). Aptamers as Novel Binding Molecules on an Antimicrobial Peptide-Armored Composite Hydrogel Wound Dressing for Specific Removal and Efficient Eradication of Pseudomonas aeruginosa.
Int J Mol Sci. 24, 4800. doi: 10.3390/ijms24054800.

Rodriguez, A.; Martell-Huguet, E.M.; González-García, M.; Alpízar-Pedraza, D.; Alba, A.; Vazquez, A.A.; Grieshober, M.; Spellerberg, B.; Stenger, S.; Münch, J.; Kissmann, A.-K.; Rosenau, F.; Wessjohann, L.A.; Wiese, S.; Ständker, L.; Otero-Gonzalez, A.J. (2023). Identification and Characterization of Three New Antimicrobial Peptides from the Marine Mollusk Nerita versicolor (Gmelin, 1791)
Int. J. Mol. Sci., 24, 3852.


Kissmann, Ann-Kathrin, Dennis Wolf, Markus Krämer, Franziska Müller, Valerie Amann, Hu Xing, Kay-Eberhard Gottschalk, Tanja Weil, Ruth Eichmann, Patrick Schäfer, and Frank Rosenau.
Polyclonal Aptamer Libraries from a FluRoot-SELEX for the Specific Labeling of the Apical and Elongation/Differentiation Zones of Arabidopsis thaliana Roots
International Journal of Molecular Sciences 23, no. 20: 12220.

Hu Xing, Yiting Zhang, Markus Krämer, Ann-Kathrin Kissmann, Marius Henkel, Tanja Weil, Uwe Knippschild, Frank Rosenau.
A Polyclonal Selex Aptamer Library Directly Allows Specific Labelling of the Human Gut Bacterium Blautia producta without Isolating Individual Aptamers 
Molecules (2022) 27, no. 17: 5693.

Vogel Verena, Olari Lia-Raluca Olari, Marie Jachmann, Sebastian J. Reich, Michelle Häring, Ann-Kathrin Kissmann, Frank Rosenau, Christian Riedel, Jan Münch, Barbara Spellerberg.
The bacteriocin Angicin interferes with bacterial membrane integrity through interaction with the mannose phosphotransferase system.
Frontiers in Microbiology (2022) 13. DOI=10.3389/fmicb.2022.991145

Katharina Kneißle, Markus Krämer, Ann-Kathrin Kissmann, Hu Xing H, Franziska Müller, Valerie Amann, Robert Noschka, Kay-Eberhard Gottschalk, Anil Bozdogan, Jakob Andersson, Tanja Weil, Barbara Spellerberg, Steffen Stenger, Frank Rosenau.
A Polyclonal SELEX Aptamer Library Allows Differentiation of Candida albicansC. auris and C. parapsilosis Cells from Human Dermal Fibroblasts.
J Fungi (Basel). (2022) 8(8):856.

Hu Xing, Ytting Zhang, Markus Krämer, Ann-Kathrin Kissmann, Valerie Amann, Heinz Fabian Raber,Tanja Weil, Kay Stieger, Uwe Knippschild, Marius Henkel, Jakob Andersson, Frank Rosenau.
A Polyclonal Aptamer Library for the Specific Binding of the Gut Bacterium Roseburia intestinalis in Mixtures with Other Gut Microbiome Bacteria and Human Stool Samples.
Int J Mol Sci. (2022) 23(14):7744.

Häring, Michelle, Valerie Amann, Ann-Kathrin Kissmann, Tilmann Herberger, Christopher Synatschke, Nicole Kirsch-Pietz, Julio A. Perez-Erviti, Anselmo J. Otero-Gonzalez, Fidel Morales-Vicente, Jakob Andersson, Tanja Weil, Steffen Stenger, Armando Rodríguez, Ludger Ständker, and Frank Rosenau.
Combination of Six Individual Derivatives of the Pom-1 Antibiofilm Peptide Doubles Their Efficacy against Invasive and Multi-Resistant Clinical Isolates of the Pathogenic Yeast 
"Candida albicansPharmaceutics 14, no. 7: 1332 (2022)

Christina Stark, Sina Münßinger, Frank Rosenau, Bernhard Johannes Eikmanns, Andreas Schwentner.
The Potential of Sequential Fermentations in Converting C1 Substrates to Higher-Value Products. Front Microbiol. (2022) 13:907577. doi: 10.3389/fmicb.2022.907577 (Review)

Ann-Kathrin Kissmann, Jakob Andersson, Anil Bozdogan, Heinz Fabian Raber, Valerie Amann, Markus Krämer, Hu Xing, Dennis Horst Kubiczek, Anil Bozdogan, Patrik Aspermair, Wolfgang Knoll, and Frank Rosenau
Polyclonal Aptamer Libraries as Binding Entities on a Graphene FET Based Biosensor for the Discrimination of Apo- and Holo- Retinol Binding Protein 4.
Nanoscale Horizons (2022)


Valerie Amann, Ann-Kathrin Kissmann, Markus Krämer, Imke Krebs, Julio A. Perez-Erviti, Anselmo J. Otero-Gonzalez, Fidel
Morales-Vicente, Armando Rodríguez, Ludger Ständker, Tanja Weil and Frank Rosenau
"Increased activities against biofilms of the pathogenic yeast Candida
albicans of optimized Pom-1 derivatives"
Pharmaceutics 2022, 14(2), 318;

Ann-Kathrin Kissmann, Jakob Andersson, Heinz Fabian Raber, Markus Krämer, Hu Xing, Dennis Horst Kubiczek, Anil Bozdogan, Patrik Aspermair, Wolfgang Knoll, and Frank Rosenau
Polyclonal Aptamer Libraries as Binding Entities on a Graphene FET Based Biosensor for the Discrimination of Apo- and Holo- Retinol Binding Protein 4.
ChemRxiv (2021). chemrxiv-2021-wdoi:10.33774/1gg5. This content is a preprint and has not been peer-reviewed yet.

Hu Xing, Ann-Kathrin Kissmann, Heinz F. Raber, Markus Krämer, Valerie Amann, Kathrin Kohn, Tanja Weil, and Frank Rosenau
Polyclonal Aptamers for Specific Fluorescence Labeling and Quantification of the Health Relevant Human Gut Bacterium Parabacteroides distasonis
Microorganisms (2021) 9, no. 11: 2284.

Patrizia Favella, Susanne Sihler, Heinz Raber, Ann-Kathrin Kissmann, Markus Krämer, Valerie Amann, Dennis Kubiczek, Jennifer Baatz, Fabian Lang, Fabian Port, Kay-Eberhard Gottschalk, Daniel Mayer, Barbara Spellerberg, Steffen Stenger, Ingrid Müller, Tanja Weil, Ulrich Ziener, and Frank Rosenau
Albumin Microspheres as “Trans-Ferry-Beads” for Easy Cell Passaging in Cell Culture Technology
Gels (2021) 7, no. 4: 176.

Markus Krämer, Ann-Kathrin Kissmann, Heinz F. Raber, Hu Xing, Patrizia Favella, Ingrid Müller, Barbara Spellerberg, Tanja Weil, Dennis Kubiczek, Susanne Sihler, Ulrich Ziener, and Frank Rosenau
BSA Hydrogel Beads Functionalized with a Specific Aptamer Library for Capturing Pseudomonas aeruginosa in Serum and Blood
International Journal of Molecular Sciences (2021) 22, no. 20: 11118.

Heinz F. Raber, Dennis H. Kubiczek, Nicholas Bodenberger, Ann-Kathrin Kissmann, Deena D’souza, Hu Xing, Daniel Mayer, Pengfei Xu, Uwe Knippschild, Barbara Spellerberg, Tanja Weil and Frank Rosenau
FluCell-SELEX Aptamers as Specific Binding Molecules for Diagnostics of the Health Relevant Gut Bacterium Akkermansia muciniphila
International Journal of Molecular Sciences (2021) 22, no. 19: 10425.

Patrizia Favella, Ann-Kathrin Kissmann, Heinz Fabian Raber, Dennis Horst Kubiczek, Patrick Bodenberger, Nicholas Emil Bodenberger, Frank Rosenau,
Diffusion-controlled release of the theranostic protein-photosensitizer Azulitox from composite of Fmoc-Phenylalanine Fibrils encapsulated with BSA hydrogels,
Journal of Biotechnology, (2021) Volume 341, 51-62, ISSN 0168-1656,

Melaine González-García, Fidel Morales-Vicente, Erbio D. Pico, Hilda Garay, Daniel G. Rivera, Mark Grieshober, Lia Raluca Olari, Rüdiger Groß, Carina Conzelmann, Franziska Krüger, Fabian Zech, Caterina Prelli Bozzo, Janis A. Müller, Alexander Zelikin, Heinz Raber, Dennis Kubiczek, Frank Rosenau, Jan Münch, Steffen Stenger, Barbara Spellerberg, Octavio L. Franco, Armando A. Rodriguez Alfonso, Ludger Ständker and Anselmo J. Otero-Gonzalez
Antimicrobial Activity of Cyclic-Monomeric and Dimeric Derivatives of the Snail-Derived Peptide Cm-p5 against Viral and Multidrug-Resistant Bacterial Strains" 
Biomolecules (2021) 11, no. 5: 745.

Heinz F. Raber, Jetmira Sejfijaj, Ann-Kathrin Kissmann, Andreas Wittgens, Melaine Gonzalez-Garcia, Annia Alba, Antonio A. Vázquez, Fidel E. Morales Vicente, Julio P. Erviti, Dennis Kubiczek, Anselmo Otero-González, Armando Rodríguez, Ludger Ständker, and Frank Rosenau.
Antimicrobial Peptides Pom-1 and Pom-2 from Pomacea poeyana Are Active against CandidaaurisC. parapsilosis and C. albicans Biofilms
Pathogens (2021). 10, no. 4: 496.


Yan Wang,  Dennis Kubiczek,  Felix Horlamus,  Heinz Fabian Raber,  Till Hennecke,  Daniel Einfalt,  Marius Henkel,  Rudolf Hausmann,  Andreas Wittgens,  Frank Rosenau
Bioconversion of lignocellulosic to high value food proteins: recombinant production of bovine and human αS1‐casein based on wheat straw lignocelluloses
Global Change Biology (GCB) Bioenergy. (2020) doi:10.1111/gcbb.12791

Heinz Fabian Raber, Thomas Heerde, Suzanne Nour El Din, Carolin Flaig, Fabienne Hilgers, Nora Bitzenhofer, Karl-Erich Jäger, Thomas Drepper, Kay-Eberhard Gottschalk, Nicholas Emil Bodenberger, Tanja Weil, Dennis Horst Kubiczek, Frank Rosenau
Azulitox—A Pseudomonas aeruginosa P28-Derived Cancer-Cell-Specific Protein Photosensitizer
Biomacromolecules (2020) doi: 10.1021/acs.biomac.0c01216.

Melaine González García, Armando Rodríguez , Annia Alba, Antonio A. Vázquez , Fidel E. Morales Vicente, Julio Pérez-Erviti , Barbara Spellerberg , Steffen Stenger, Mark Grieshober, Carina Conzelmann, Jan Münch , Heinz Raber, Dennis Kubiczek, Frank Rosenau, Sebastian Wiese, Ludger Ständker and Anselmo Otero-González
New Antibacterial Peptides from the Freshwater Mollusk Pomacea poeyana (Pilsbry, 1927)
Biomolecules (2020), 10, 1473;

Andreas Wittgens, Frank Rosenau
Heterologous Rhamnolipid Biosynthesis: Advantages, Challenges, and the Opportunity to Produce Tailor-Made Rhamnolipids.
Front. Bioeng. Biotechnol. (2020) |

Tommaso Marchesi D'Alvise, Sean Harvey, Lisa Hueske, Jolanta Szelwicka, Lothar Veith, Tuomas PJ Knowles, Dennis Kubiczek, Carolin Flaig, Fabian Port, Kay‐E Gottschalk, Frank Rosenau, Bartlomiej Graczykowski, George Fytas, Francesco S Ruggeri, Katrin Wunderlich, Tanja Weil
Ultrathin Polydopamine Films with Phospholipid Nanodiscs Containing a Glycophorin A Domain
Advanced Functional Materials (2020).

Dennis Horst Kubiczek, Heinz Fabian Raber, Nicholas Emil Bodenberger, Thomas Oswald, Melis Sahan, Daniel Mayer, Sebastian Wiese, Steffen Stenger, Tanja Weil, Frank Rosenau
The Diversity of a Polyclonal FluCell‐SELEX Library Outperforms Individual Aptamers as Emerging Diagnostic Tools for the Identification of Carbapenem Resistant Pseudomonas aeruginosa
Chemistry – A European Journal (2020).

Dennis Kubiczek, Heinz Raber, Melaine Gonzalez-García, Fidel Morales-Vicente, Ludger Staendker, Anselmo J Otero-Gonzalez, Frank Rosenau
Derivates of the Antifungal Peptide Cm-p5 Inhibit Development of Candida auris Biofilms In Vitro
Antibiotics (2020) 9, 363;

Kubiczek D, Flaig C, Raber H, Dietz S, Kissmann AK, Heerde T, Bodenberger N, Wittgens A, González-Garcia M, Kang F, Franco OL, Staendker L, Otero-González AJ, Walther P, Gottschalk KE, Weil T, Rosenau F.
A Cerberus-Inspired Anti-Infective Multicomponent Gatekeeper Hydrogel against Infections with the Emerging "Superbug" Yeast Candida auris.
Macromol Biosci. (2020) doi:10.1002/mabi.202000005. PubMed PMID: 32104975.

Bator I, Wittgens A, Rosenau F, Tiso T, Blank LM.
Comparison of Three Xylose Pathways in Pseudomonas putida KT2440 for the Synthesis of Valuable Products
Front Bioeng Biotechnol (2020). doi:10.3389/fbioe2019.00480


Vicente FEM, González-Garcia M, Diaz Pico E, Moreno-Castillo E, Garay HE, Rosi PE, Jimenez AM, Campos-Delgado JA, Rivera DG, Chinea G, Pietro RCLR, Stenger S, Spellerberg B, Kubiczek D, Bodenberger N, Dietz S, Rosenau F, Paixão MW, Ständker L, Otero-González AJ.
Design of a Helical-Stabilized, Cyclic, and Nontoxic Analogue of the Peptide Cm-p5 with Improved Antifungal Activity.
ACS Omega. (2019) 4(21):19081-19095. doi: 10.1021/acsomega.9b02201. eCollection 2019 Nov 19. PubMed PMID: 31763531; PubMed Central PMCID: PMC6868880.

Horlamus F, Wang Y, Steinbach D, Vahidinasab M, Wittgens A, Rosenau F, Henkel M, Hausmann R.
Potential of biotechnological conversion of lignocellulose hydrolyzates by Pseudomonas putida KT2440 as a model organism for a bio‐based economy.
Global Change Biology (GCB) Bioenergy. (2019). doi:10.1111/gcbb.12647

Arnold S, Henkel M, Wanger J, Wittgens A, Rosenau F, Hausmann R.
Heterologous rhamnolipid biosynthesis by P. putida KT2440 on bio-oil derived small organic acids and fractions
AMB Expr. 9:80. doi: 10.1186/s13568-019-0804-7


Horlamus F, Wittgens A, Noll P, Michler J, Müller I, Weggenmann F, Oellig C, Rosenau F, Henkel M, Hausmann R .
One‐step bioconversion of hemicellulose polymers to rhamnolipids with Cellvibrio japonicus: A proof‐of‐concept for a potential host strain in future bioeconomy.
Global Change Biology (GCB) Bioenergy. 2018;00:1–9.

Wittgens A, Rosenau F.
On the road towards tailor-made rhamnolipids: current state and perspectives.
Appl Microbiol Biotechnol. 2018 Jul 21. doi: 10.1007/s00253-018-9240-x.

Bodenberger, N; Kubiczek, D.; Halbgebauer, D.; Rimola, V.; Wiese, S.; Mayer, D.; Rodriguez Alfonso, A.A.; Ständker, L.; Stenger, S.; Rosenau, F.
Lectin-Functionalized Composite Hydrogels for "Capture-and-Killing" of Carbapenem-Resistant Pseudomonas aeruginosa. Biomacromolecules.
Apr 25. doi: 10.1021/acs.biomac.8b00089.

Wittgens, A.; Santiago-Schuebel, B.; Henkel, M.; Tiso, T.; Blank, L.M.; Hausmann, R.; Hofmann, D.; Wilhelm, S.; Jaeger, K.E.; Rosenau, F.
Heterologous production of long-chainrhamnolipids from Burkholderia glumae in Pseudomonas putida-a step forward totailor-made rhamnolipids.
Appl Microbiol Biotechnol. 102(3):1229-1239. doi: 10.1007/s00253-017-8702-x.


Tiso, T.; Zauter R, Tulke H, Leuchtle B, Li WJ, Behrens B, Wittgens A, RosenauF, Hayen H, Blank LM.
Designer rhamnolipids by reduction of congener diversity: production and characterization.
Microb Cell Fact. 16(1):225. doi: 10.1186/s12934-017-0838-y.

Bodenberger, N.; Kubiczek, D.; Rosenau, F.
Easy Manipulation of Architectures in Protein-based Hydrogels for Cell Culture Applications.
J Vis Exp. (126). doi: 10.3791/55813.

Bodenberger, N.; Kubiczek, D.; Trösch, L.; Gawanbacht, A.; Wilhelm, S.; Tielker, D.; Rosenau, F.
Lectin-mediated reversible immobilization of human cells into a glycosylated macroporous protein hydrogel as a cell culture matrix.
Sci Rep. 7(1):6151. doi: 10.1038/s41598-017-06240-w.

Bodenberger, N.; Kubiczek, D.; Paul, P.; Preising, N.; Weber L.; Bosch, R.; Hausmann, R.; Gottschalk, K.E.; Rosenau, F.
Beyond bread and beer: whole cell protein extracts from baker's yeast as a bulk source for 3D cell culture matrices.
Appl Microbiol Biotechnol. 101(5):1907-1917. doi: 10.1007/s00253-016-7982-x.


Bodenberger, N.; Kubiczek, D.; Abrosimova, I.; Scharm, A.; Kipper, F.; Walther, P.; Rosenau, F. Evaluation of methods for pore generation and their influence on physio-chemical properties of a protein based hydrogel.
Biotechnol Rep (Amst). 12:6-12. doi: 10.1016/j.btre.2016.09.001.

Wittgens, A.; Kovacic, F.; Müller, M.M.; Gerlitzki, M.; Santiago-Schübel, B.; Hofmann, D.; Tiso, T.; Blank, L.M.; Henkel, M.; Hausmann, R.; Syldatk, C.; Wilhelm, S.; Rosenau F.
Novel insights into biosynthesis and uptake ofrhamnolipids and their precursors.
Appl. Microbiol Biotechnol. 101(7):2865-2878. doi: 10.1007/s00253-016-8041-3.

Beuker, J.; Barth, T.; Steier, A.; Wittgens, A.; Rosenau, F.; Henkel, M.; Hausmann, R.
High titer heterologous rhamnolipid production.
AMB Express. 6(1):124. doi: 10.1186/s13568-016-0298-5.

Bodenberger, N.; Paul, P.; Kubiczek, D.; Walther, P.; Gottschalk, K.E; Rosenau, F.;
A novel cheap and easy to handle protein hydrogel for 3D cell culture applications: a high stability matrix with tunable elasticity and cell adhesion properties.
ChemistrySelect 7:1353-1360

Tiso, T.; Sabelhaus, P.; Behrens, B.; Wittgens, A.; Rosenau, F.; Hayen, H.; Blank, L.M.
Creating metabolic demand as an engineering strategy in Pseudomonas putida -Rhamnolipid synthesis as an example.
Metab Eng Commun. 3:234-244. doi:10.1016/j.meteno.2016.08.002.

Thies, S.; Rausch, S.C.; Kovacic, F.; Schmidt-Thaler, A.; Wilhelm, S.; Rosenau, F.; Daniel, R.; Streit, W.; Pietruszka, J.; Jaeger, K.E.
Metagenomic discovery of novel enzymes and biosurfactants in a slaughterhouse biofilm microbial community.
Sci Rep. 6:27035. doi: 10.1038/srep27035.

Beuker, J.; Steier, A.; Wittgens, A.; Rosenau, F.; Henkel, M.; Hausmann, R.
Integrated foam fractionation for heterologous rhamnolipid production with recombinant Pseudomonas putida in a bioreactor.
AMB Express. 6(1):11. doi:

Thies, S.; Santiago-Schübel, B.; Kovačić, F.; Rosenau, F.; Hausmann, R.; Jaeger, K.E.
Heterologous production of the lipopeptide biosurfactant serrawettin W1 in Escherichia coli.
J Biotechnol. 181:27-30. doi: 10.1016/j.jbiotec.2014.03.037.

Pelzer, A.; Polen, T.; Funken, H.; Rosenau, F.; Wilhelm, S.; Bott, M.; Jaeger, K.E.
Subtilase SprP exerts pleiotropic effects in Pseudomonas aeruginosa.
Microbiologyopen. 3(1):89-103. doi: 10.1002/mbo3.150.

Tielen, P.; Kuhn, H.; Rosenau, F.; Jaeger, K.E.; Flemming, H.C.; Wingender, J.
Interaction between extracellular lipase LipA and the polysaccharide alginate of Pseudomonas aeruginosa.
BMC Microbiol. 13:159. doi: 10.1186/1471-2180-13-159.

Loeschcke, A.; Markert, A.; Wilhelm, S.; Wirtz, A.; Rosenau, F.; Jaeger, K.E.; Drepper, T. 
TREX: a universal tool for the transfer and expression of biosynthetic pathways in bacteria.
ACS Synth Biol.  2(1):22-33. doi: 10.1021/sb3000657.

Funken, H.; Bartels, K.M.; Wilhelm, S.; Brocker, M.; Bott, M.; Bains, M.; Hancock, R.E.;Rosenau, F.; Jaeger, K.E.
Specific association of lectin LecB with the surface ofPseudomonas aeruginosa: role of outer membrane protein OprF.
PLoS One. 7(10):e46857. doi: 10.1371/journal.pone.0046857

Troeschel, S.C.; Thies, S.; Link, O.; Real, C.I.; Knops, K.; Wilhelm, S.; Rosenau, F.; Jaeger, K.E. Novel broad host range shuttle vectors for expression in Escherichia coli, Bacillus subtilis and Pseudomonas putida.
J Biotechnol. 161(2):71-9. doi: 10.1016/j.jbiotec.2012.02.020.

Tiso, T.; Wittgens, A.; Rosenau, F.; Blank, L.M.
Biotensid‐Produktion aus nachwachsenden Rohstoffen mit rekombinanten Mikroorganismen.
Chemie Ingenieur Technik 84 (8), 1196-1196

Wittgens, A.; Tiso, T.; Arndt, T.T.; Wenk, P.; Hemmerich, J.; Müller, C.; Wichmann, R.; Küpper, B.; Zwick, M.; Wilhelm, S.; Hausmann, R.; Syldatk, C.; Rosenau, F.; Blank, L.M.
Growth independent rhamnolipid production from glucose using the non-pathogenic Pseudomonas putida KT2440.
Microb Cell Fact. 10:80. doi:10.1186/1475-2859-10-80.

Fuchs, V.; Jaeger, K.E.; Wilhelm, S.; Rosenau, F.
The BapF protein from Pseudomonas aeruginosa is a β-peptidyl aminopeptidase.
World Journal of Microbiology and Biotechnology 27(3) 713-718

Funken, H.; Knapp, A.; Vasil, M.L.; Wilhelm, S.; Jaeger, K.E.; Rosenau, F.
The lipase LipA (PA2862) but not LipC (PA4813) from Pseudomonas aeruginosa influences regulation of pyoverdine production and expression of the sigma factor PvdS.
J Bacteriol. 193(20):5858-60. doi: 10.1128/JB.05765-11.

Wilhelm; S.; Rosenau, F.; Kolmar, H.; Jaeger, K.E.
Autotransporters with GDSL passenger domains: molecular physiology and biotechnological applications.
Chembiochem. 12(10):1476-85. doi: 10.1002/cbic.201100013.

Bartels, K.M.; Funken, H.; Knapp, A.; Brocker, M.; Bott, M.; Wilhelm, S.; Jaeger, K.E.; Rosenau, F.
Glycosylation is required for outer membrane localization of the lectin LecB in Pseudomonas aeruginosa.
J Bacteriol. 193(5):1107-13. doi: 10.1128/JB.01507-10.

Hoge, R.; Laschinski, M.; Jaeger, K.E.; Wilhelm, S.; Rosenau F.
The subcellular localization of a C-terminal processing protease in Pseudomonas aeruginosa.
FEMSMicrobiol Lett. 316(1):23-30. doi: 10.1111/j.1574-6968.2010.02181.x.

Rosenau, F.; Isenhardt, S.; Gdynia, A.; Tielker, D.; Schmidt, E.; Tielen, P.; Schobert, M.; Jahn, D.; Wilhelm, S.; Jaeger, K.E.
Lipase LipC affects motility, biofilm formation and rhamnolipid production in pseudomonas aeruginosa.
FEMS Microbiol Lett.309(1):25-34. doi: 10.1111/j.1574-6968.2010.02017.x.

Tielen, P.; Rosenau, F.; Wilhelm, S.; Jaeger, K.E.; Flemming, H.C.; Wingender, J.
Extracellular enzymes affect biofilm formation of mucoid Pseudomonas aeruginosa.
Microbiology. 156(Pt 7):2239-52. doi: 10.1099/mic.0.037036-0.

Wilhelm, S.; Kolmar, H.; Rosenau, F.
Bacterial secretion systems for use in biotechnology: autotransporter-based ultra-high throughput cell-surface display and screening of large protein libraries
Handbook of hydrocarbon and lipid microbiology, 4587-4600

Hoge, R.; Pelzer, A.; Rosenau, F.; Wilhelm, S.
Weapons of a pathogen: proteases and their role in virulence of Pseudomonas aeruginosa.
Current research, technology and education topics in applied microbiology and microbial biotechnology. 2:383-95 Formatex Research Center

Johansson, E.M.; Crusz, S.A.; Kolomiets, E.; Buts, L.; Kadam, R.U.; Cacciarini, M.; Bartels, K.M.; Diggle, S.P.; Cámara, M.; Williams, P.; Loris, R.; Nativi, C.; Rosenau, F.; Jaeger, K.E.; Darbre, T., Reymond, J.L.
Inhibition and dispersion of Pseudomonas aeruginosa biofilms by glycopeptide dendrimers targeting the fucose-specific lectin LecB.
Chem Biol. 15(12):1249-57. doi: 10.1016/j.chembiol.2008.10.009.

Becker, S.; Höbenreich, H.; Vogel, A.; Knorr, J.; Wilhelm, S.; Rosenau, F.; Jaeger, K.E.; Reetz, M.T.; Kolmar, H.
Single-cell high-throughput screening to identify enantioselective hydrolytic enzymes. Angew Chem Int Ed Engl. 47(27):5085-8.doi: 10.1002/anie.200705236.

Becker, S.; Höbenreich, H.; Vogel, A.; Knorr, J.; Wilhelm, S.; Rosenau, F.; Jaeger, K.E.;Reetz, M.T.; Kolmar, H.
Einzelzellbasierte Hochdurchsatz‐Durchmusterung zur Identifizierung enantioselektiver hydrolytischer Enzyme.
Angewandte Chemie. 120(27) 5163-5166

Hausmann, S.; Wilhelm, S.; Jaeger, K.E.; Rosenau, F.
Mutations towards enantioselectivity adversely affect secretion of Pseudomonas aeruginosa lipase.
FEMS Microbiol Lett. 282(1):65-72. doi: 10.1111/j.1574-6968.2008.01107.x.

Schneiker, S.; Perlova, O.; Kaiser, O.; Gerth, K.; Alici, A.; Altmeyer, M.O.; Bartels, D.; Bekel, T.; Beyer, S.; Bode, E.; Bode, H.B.; Bolten, C.J.; Choudhuri, J.V.; Doss, S.; Elnakady, Y.A.; Frank, B.; Gaigalat, L.; Goesmann, A.; Groeger, C.; Gross, F.; Jelsbak, L.; Jelsbak, L.; Kalinowski, J.; Kegler, C.; Knauber, T.; Konietzny, S.; Kopp, M.; Krause, L.; Krug, D.; Linke, B.; Mahmud, T.; Martinez-Arias, R.; McHardy, A.C.; Merai, M.; Meyer, F.; Mormann, S.; Muñoz-Dorado, J.; Perez, J.; Pradella, S.; Rachid, S., Raddatz, G.; Rosenau, F.; Rückert, C.; Sasse, F.; Scharfe, M.; Schuster, S.C.; Suen, G.; Treuner-Lange, A., Velicer, G.J.; Vorhölter, F.J.; Weissman, K.J.; Welch, R.D.; Wenzel, S.C.; Whitworth, D.E.; Wilhelm, S.; Wittmann, C.; Blöcker, H.; Pühler, A.; Müller, R.
Complete genome sequence of the myxobacterium Sorangium cellulosum.
Nat Biotechnol. 25(11):1281-9.

Johansson, M.V.A.; Kolomiets, E., Rosenau, F.; Jaeger, K.E.; Darbre, T.; Reymond, J.L.
Combinatorial variation of branching length and multivalency in a large (390625 member) glycopeptide dendrimer library: ligands for fucose-specific lectins
New journal of chemistry, 31(7)1291-1299

Wilhelm, S.; Gdynia, A.; Tielen, P.; Rosenau, F.; Jaeger, K.E.
The autotransporter esterase EstA of Pseudomonas aeruginosa is required for rhamnolipid production, cell motility, and biofilm formation.
J Bacteriol. 189(18):6695-703.

Boekema, B.K.; Beselin, A.; Breuer, M.; Hauer, B.; Koster, M.; Rosenau, F.; Jaeger, K.E.; Tommassen, J.
Hexadecane and Tween 80 stimulate lipase production in Burkholderia glumae by different mechanisms.
Appl Environ Microbiol. 73(12):3838-44.

Wilhelm, S.; Rosenau, F.; Becker, S.; Buest, S.; Hausmann, S.; Kolmar, H.; Jaeger, K.E. Functional cell-surface display of a lipase-specific chaperone.
Chembiochem. 8(1):55-60.

Tielker, D.; Rosenau, F.; Bartels, K.M.; Rosenbaum, T.; Jaeger, K.E.
Lectin-based affinity tag for one-step protein purification.
Biotechniques. 41(3):327-32.

Drepper, T.; Eggert, T.; Hummel, W.; Leggewie, C.; Pohl, M.; Rosenau, F.; Wilhelm, S.; Jaeger, K.E.
Novel biocatalysts for white biotechnology.
Biotechnol J. 1(7-8):777-86.

Tielker, D.; Hacker, S.; Loris, R.; Strathmann, M.; Wingender, J.; Wilhelm, S.; Rosenau, F.; Jaeger, K.E.
Pseudomonas aeruginosa lectin LecB is located in the outer membrane and is involved in biofilm formation.
Microbiology. 151(Pt 5):1313-23.

Drepper, T.; Arvani, S.; Rosenau, F.; Wilhelm, S.; Jaeger, K.E.
High-level transcription of large gene regions: a novel T(7) RNA-polymerase-based system for expression of functional hydrogenases in the phototrophic bacterium Rhodobacter capsulatus.
Biochem Soc Trans. 33(Pt 1):56-8.

Rosenau, F.; Tommassen, J.; Jaeger, K.E.
Lipase-specific foldases.
Chembiochem. 5(2):152-61..

Sonnleitner, E.; Hagens, S.; Rosenau, F.; Wilhelm, S.; Habel, A.; Jäger, K.E.; Bläsi, U.
Reduced virulence of a hfq mutant of Pseudomonas aeruginosa O1.
Microb Pathog. 35(5):217-28.
PubMed PMID: 14521880.

Rosenau, F.; Jaeger, K.
Bacterial lipases from Pseudomonas: regulation of gene expression and mechanisms of secretion.
Biochimie. 82(11):1023-32.