Publikationen
54.
53. Jialei Song, Natalie Yashoda Dikwella, Daniela Sinske, Francesco Roselli, Bernd Knöll
SRF deletion results in earlier disease onset in a mouse model of amyotrophic lateral sclerosis
Journal of Clinical Investigation insight, 2023 Jun 20; e167694. doi: 10.1172/jci.insight.167694. Online ahead of print.
52. Shun Li, Florian Olde Heuvel, Rida Rehman, Oumayma Aousji, Albrecht Froehlich, Zhenghui Li, Rebecca Jark, Wanhong Zhang, Alison Conquest, Sarah Woelfle, Michael Schoen, Caitlin C O Meara, Richard Lee Reinhardt, David Voehringer, Jan Kassubek, Albert Ludolph, Markus Huber-Lang, Bernd Knöll, Maria Cristina Morganti-Kossmann, Marisa M Brockmann, Tobias Boeckers, Francesco Roselli
Interleukin-13 and its receptor are synaptic proteins involved in plasticity and neuroprotection.
Nat Commun. 2023 Jan 13;14(1):200. doi: 10.1038/s41467-023-35806-8.
51. Albrecht Fröhlich, Florian Olde Heuvel, Rida Rehman, Sruthi Sankari Krishnamurthy, Shun Li, Zhenghui Li, David Bayer, Alison Conquest, Anna M. Hagenston, Albert Ludolph, Markus Huber‑Lang, Tobias Boeckers, Bernd Knöll, Maria Cristina Morganti‑Kossmann, Hilmar Bading and Francesco Roselli
Neuronal nuclear calcium signaling suppression of microglial reactivity is mediated by osteoprotegerin after traumatic brain injury
Journal of Neuroinflammation, 2022 November (19), doi.org/10.1186/s12974-022-02634-4.
50. Kuchler O, Gerlach J, Vomhof Th, Hettich J, Steinmetz J, Christof J, Gebhardt M, Michaelis J, Knöll B
Single-molecule tracking (SMT) and localization of SRF and MRTF transcription factors during neuronal stimulation and differentiation
Open Biol, 2022 May;12(5):210383, doi: 10.1098/rsob.210383. Epub 2022 May 11.
49. Meyer Zu Reckendorf S, Moser D, Blechschmidt A, Joga VN, Sinske D, Hegler J, Deininger S, Catanese A, Vettorazzi S, Antoniadis G, Boeckers T, Knöll B
Motoneuron-specific PTEN deletion in mice induces neuronal hypertrophy and also regeneration after facial nerve injury.
J Neurosci. 2022 Feb 10;JN-RM-1305-21. doi: 10.1523/JNEUROSCI.1305-21.2022.
48. Meyer zu Reckendorf S, Brand C, Pedro MT, Hegler J, Schilling CS, Bindila L, Antoniadis G, Knöll B
Reduced injury-induced adaptation of lipid metabolism in human compared to murine Schwann cells.
Nat Commun. 2020 May 1;11(1):2123. doi: 10.1038/s41467-020-15915-4.
47. Lüningschrör P, Werner G, Stroobants S, Kakuta S, Dombert B, Sinske D, Wanner R, Lüllmann-Rauch R, Wefers B, Wurst W, D'Hooge R, Uchiyama Y, Sendtner M, Haass C, Saftig P, Knöll B, Capell A, Damme M.
The FTLD Risk Factor TMEM106B Regulates the Transport of Lysosomes at the Axon Initial Segment of Motoneurons.
Cell Rep. 2020 Mar 10;30(10):3506-3519.e6. doi: 10.1016/j.celrep.2020.02.060.
46. Wanner R and Knöll B
Interference with SRF expression in skeletal muscles reduces peripheral nerve regeneration in mice.
Sci Rep. 2020 Mar 24;10(1):5281. doi: 10.1038/s41598-020-62231-4.
45. Förstner P and Knöll B
Interference of neuronal activity‐mediated gene expression through serum response factor deletion enhances mortality and hyperactivity after traumatic brain injury.
FASEB J 2019, Dec 23. doi.org/10.1096/fj.201902257RR
44. Weber B, Lackner I, Haffner-Luntzer M, Palmer A, Pressmar J, Scharffetter-Kochanek K, Knöll B, Schrezenemeier H, Relja B, Kalbitz M.
Modeling trauma in rats: similarities to humans and potential pitfalls to consider.
J Transl Med. 2019 Sep 5;17(1):305. doi: 10.1186/s12967-019-2052-7.
43. Schilling C, Lickfett S, Sieste S, Ruggeri FS, Sneideris T, Dutta A, Bereau T, Naraghi R, Sinske D, Knowles TPJ, Synatschke CV, Weil, T* and Knöll B*
Sequence‐Optimized Peptide Nanofibers as Growth Stimulators for Regeneration of Peripheral Neurons.
Advanced Functional Materials 2019, 29. DOI: 10.1002/adfm.201809112
42. Olde Heuvel F, Holl S, Chandrasekar A, Li Z, Wang Y, Rehman R, Förstner P, Sinske D, Palmer A, Wiesner D, Ludolph A, Huber-Lang M, Relja B, Wirth T, Röszer T, Baumann B, Boeckers T, Knöll B, Roselli F.
STAT6 mediates the effect of ethanol on neuroinflammatory response in TBI.
Brain Behav Immun. 2019 Jun 15. pii: S0889-1591(19)30254-5.
41. Abdellatif MEA, Hipp L, Plessner M, Walther P, Knöll B
Indirect visualization of endogenous nuclear actin by correlative light and electron microscopy (CLEM) using an actin-directed chromobody.
Histochem Cell Biol. 2019 Aug;152(2):133-143.
40. Wanner R, Abaei A, Rasche V, Knöll B
Three-Dimensional In vivo Magnetic Resonance Imaging (MRI) of Mouse Facial Nerve Regeneration.
Front Neurol. 2019 Apr 2;10:310.
39. Hipp L, Beer J, Kuchler O, Reisser M, Sinske D, Michaelis J, Gebhardt JCM, Knöll B
Single-molecule imaging of the transcription factor SRF reveals prolonged chromatin-binding kinetics upon cell stimulation.
Proc Natl Acad Sci U S A. 2019 Jan 15;116(3):880-889.
38. Autonomous Ultrafast Self-Healing Hydrogels by pH-Responsive Functional Nanofiber Gelators as Cell Matrices.
Gacanin J, Hedrich J, Sieste S, Glaßer G, Lieberwirth I, Schilling C, Fischer S, Barth H, Knöll B, Synatschke CV, Weil T.
Adv Mater. 2018 Nov 9:e1805044
37. Röcker AE, Müller JA, Dietzel E, Harms M, Krüger F, Heid C, Sowislok A, Riber CF, Kupke A, Lippold S, von Einem J, Beer J, Knöll B, Becker S, Schmidt-Chanasit J, Otto M, Vapalahti O, Zelikin AN, Bitan G, Schrader T, Münch J.
The molecular tweezer CLR01 inhibits Ebola and Zika virus infection.
Antiviral Res. 2018 Apr;152:26-35.
36. Sieste S, Mack T, Synatschke CV, Schilling C, Meyer zu Reckendorf C, Pendi L, Harvey S, Ruggeri FS, Knowles TPJ, Meier C, Ng DYW, Weil T*, and Knöll B*
Water-Dispersible Polydopamine-Coated Nanofibers for Stimulation of Neuronal Growth and Adhesion.
Adv Healthc Mater. 2018 Jun;7(11):e1701485
35. Förstner P, Rehman R, Anastasiadou S, Haffner-Luntzer M, Sinske D, Ignatius A, Roselli, F, and Knöll B
Neuroinflammation after traumatic brain injury (TBI) is enhanced in activating transcription factor 3 (ATF3) mutant mice.
Journal of Neurotrauma 2018 Feb 20.
34. Chandrasekar A, Aksan B, Heuvel FO, Förstner P, Sinske D, Rehman R, Palmer A, Ludolph A, Huber-Lang M, Böckers T, Mauceri D*, Knöll B*, Roselli F*.
Neuroprotective effect of acute ethanol intoxication in TBI is associated to the hierarchical modulation of early transcriptional responses.
Experimental Neurology 2018 Jan 4;3.
33. Wanner R, Gey M, Abaei A, Warnecke D, de Roy L, Dürselen L, Rasche V, Knöll B
Functional and Molecular Characterization of a Novel Traumatic Peripheral Nerve-Muscle Injury Model.
Neuromolecular Med. 2017 Jul 8.
32. Lösing P, Niturad CE, Harrer M, Reckendorf CMZ, Schatz T, Sinske D, Lerche H, Maljevic S, Knöll B
SRF modulates seizure occurrence, activity induced gene transcription and hippocampal circuit reorganization in the mouse pilocarpine epilepsy model.
Mol Brain. 2017 Jul 17;10(1):30
31. Zimprich A, Mroz G, Meyer Zu Reckendorf C, Anastasiadou S, Förstner P, Garrett L, Hölter SM, Becker L, Rozman J, Prehn C, Rathkolb B, Moreth K, Wurst W, Klopstock T, Klingenspor M, Adamski J, Wolf E, Bekeredjian R, Fuchs H, Gailus-Durner V, de Angelis MH, Knöll B
Serum Response Factor (SRF) Ablation Interferes with Acute Stress-Associated Immediate and Long-Term Coping Mechanisms.
Mol Neurobiol. 2016 Dec 2.
30. Gey M, Wanner, R, Schilling C, Pedro MT, Sinske D, Knöll B
Atf3 mutant mice show reduced axon regeneration and impaired regeneration-associated gene induction after peripheral nerve injury.
Open Biology. 2016 Aug 31.
29. Anastasiadou S and Knöll B
The multiple sclerosis drug fingolimod (FTY720) stimulates neuronal gene expression, axonal growth and regeneration.
Exp. Neurology. 2016 Mar 11.
28. Meyer Zu Reckendorf C, Anastasiadou S, Bachhuber F, Franz-Wachtel M, Macek B, Knöll B
Proteomic analysis of SRF associated transcription complexes identified TFII-I as modulator of SRF function in neurons.
Eur J Cell Biol. 2015 Nov 10. pii: S0171-9335(15)30019-4.
27. Anastasiadou S, Liebenehm S, Sinske D, Meyer Zu Reckendorf C, Moepps B, Nordheim A, Knöll B
Neuronal expression of the transcription factor serum response factor modulates myelination in a mouse multiple sclerosis model.
Glia. 2015 Feb 2.
26. Stern S and Knöll B
CNS axon regeneration inhibitors stimulate an immediate early gene response via MAP kinase-SRF signaling.
Molecular Brain 2014, 7:86.
25. Stern S, Haverkamp S, Sinske D, Tedeschi A, Naumann U, Di Giovanni S, Kochanek S, Nordheim A, Knöll B
The Transcription Factor Serum Response Factor Stimulates Axon Regeneration through Cytoplasmic Localization and Cofilin Interaction.
J Neurosci. 2013 Nov 27;33(48):18836-48.
24. Kokai E, Beck H, Weissbach J, Arnold F, Sinske D, Sebert U, Gaiselmann G, Schmidt V, Walther P, Münch J, Posern G, Knöll B
Analysis of nuclear actin by overexpression of wild-type and actin mutant proteins.
Histochem Cell Biol. 2013 Oct 4.
23. Weschenfelder M, Weth F, Knöll B*, Bastmeyer M*.
The stripe assay: studying growth preference and axon guidance on binary choice substrates in vitro.
Methods Mol Biol. 2013;1018:229-46.
22. Beck H, Flynn K, Lindenberg KS, Schwarz H, Bradke F, Di Giovanni S, Knöll B
Serum Response Factor (SRF)-cofilin-actin signaling axis modulates mitochondrial dynamics.
Proc Natl Acad Sci U S A. 2012 Sep 18;109(38):E2523-32.
21. Stern C, Sinske D, Knöll B
Serum response factor (SRF) modulates neuron survival during peripheral axon injury.
The Journal of Neuroinflammation, 2012 Apr 26;9:78.
20. Knöll B
Serum Response Factor (SRF) mediated gene activity in physiological and pathological processes of neuronal motility.
Frontiers in Neuroscience 2011, Oct 11.
19. Meier C, Anastasiadou S,* Knöll B
Ephrin-A5 Suppresses Neurotrophin Evoked Neuronal Motility, ERK Activation and Gene Expression.
PLoS One. 2011;6(10):e26089. Epub 2011 Oct 11.
18. Knöll B
Actin-mediated gene expression in neurons: the MRTF-SRF connection.
Biological Chemistry 2010 Apr 6.
17. Stritt C, Knöll B
Reelin signalling targets SRF (Serum Response Factor) gene activity during hippocampal development.
Molecular and Cellular Biology 2010 Apr;30(7):1828-37.
16. Harting K, Knöll B
Sirtuin deacetylases in brain function.
European Journal of Cell Biology 2010 Feb-Mar;89(2-3):262-9.
15. Knöll B*, Nordheim A*
Transcriptional regulation in the developing and mature nervous systems: the SRF paradigm.
Trends Neurosci. 2009 Juli 28
14. Stern S, Debre E, Stritt C, Posern G, Berger J, Knöll B
An Actin-Serum Response Factor (SRF) cytoskeletal-nuclear crosstalk regulates neuronal motility.
The Journal of Neuroscience 2009, Apr 8;29(14):4512-8.
13. Stritt C, Stern S, Harting K, Sinske D, Manke T, Schwarz H, Vingron M, Nordheim A, Knöll B
Paracrine control of oligodendrocyte differentiation by Serum Response Factor (SRF) mediated gene expression in neurons.
Nature Neuroscience 2009 Apr;12(4):418-27.
12. Plachez C, Andrews W, Liapi A, Knöll B, Drescher U, Rashid T, Mankoo B, Zhe L, Mambetisaeva E, Camurri L, Annan A, Richards L , Guthrie S, Sundaresan V
Mice deficient in Robo2 demonstrate defects in axon guidance in the visual system.
Molecular and Cellular Neuroscience 2008 Apr;37(4):719-30.
11. Pandithage R, Lilischkis R, Jedamzik R, Lüscher-Firzlaff J, Vervoorts J, Harting K, Lasonder E, Knöll B*, Lüscher B*
The regulation of SIRT2 function by cyclin-dependent kinases affects cell motility.
Journal of Cell Biology 2008 Mar 10;180(5):915-29.
* gemeinsame Senior-Autorenschaft
10. Knöll B*, Weinl C, Nordheim A, Bonhoeffer F
Stripe assay to examine axonal guidance and cell migration.
Nature Protocols 2007 May;2(5):1216-1224. *Korrespondierender Autor
10. Knöll B*, Weinl C, Nordheim A, Bonhoeffer F
Stripe assay to examine axonal guidance and cell migration.
Nature Protocols 2007 May;2(5):1216-1224. *Korrespondierender Autor
9. Carvalho R , Beutler M , Marler KJM , Knöll B , Becker-Barroso E , Heintzmann R , Ng T, Drescher U
Silencing of EphA3 through a novel cis interaction with ephrinA5.
Nature Neuroscience 2006, Mar;9(3):322-30.
8. Knöll B, Kretz O, Fiedler C, Alberti S, Schütz G, Frotscher M, Nordheim A
SRF controls neuronal circuit assembly in the hippocampus.
Nature Neuroscience 2006 Feb; 9(2):195-204.
7. Rashid T, Upton AL, Blentic A, Ciossek T, Knöll B, Thompson ID, Drescher U
Opposing gradients of Ephrin-As and EphA7 in the superior colliculus are essential for topographic mapping in the mammalian visual system.
Neuron 2005 Jul 7;47(1):57-69.
6. Knöll B, Drescher U
Src family kinases are involved in EphA receptor mediated retinal axon guidance.
The Journal of Neuroscience 2004 Jul 14;24(28):6248-57.
5. Sundaresan V, Mambetisaeva E, Andrews W, Annan A, Knöll B, Tear G, Bannister L
Dynamic expression patterns of Robo in the developing murine nervous system.
Journal of Comparative Neurology 2004 Jan 19; 468(4): 467-81.
4. Knöll B, Schmidt H, Guthrie S, Andrews, W, Pini A, Sundaresan V, Drescher U
On the topographic targeting of basal vomeronasal axons through Slit-mediated chemorepulsion.
Development 2003 Nov;130(21):5073-82.
3. Knöll B, Drescher U
Ephrin-As as receptors in topographic projections.
Trends Neurosci. 2002 Mar;25(3):145-9.
2. Knöll B, Isenmann S, Kilic E, Walkenhorst J, Engel S, Wehinger J, Bähr M, Drescher U
Graded expression patterns of ephrin-As in the superior colliculus after lesion of the adult mouse optic nerve.
Mechanisms of Development 2001 Aug;106(1-2):119-27.
1. Knöll B, Zarbalis K, Wurst W, Drescher U
A role for the EphA family in the topographic targeting of vomeronasal axons.
Development 2001 Mar;128(6):895-906.