Subproject 1:

Stefan O. Schönland, Stefanie Huhn:

SEQUENCE DIVERSITY OF THE LIGHT CHAINS IN TWO CLINICAL VARIANTS OF AL AMYLOIDOSIS

www.klinikum.uni-heidelberg.de/zentrum-fuer-innere-medizin-medizin-klinik/innere-medizin-v-haematologie-onkologie-und-rheumatologie/behandlungsspektrum/haematologie/amyloidose

Subproject 2:

Ute Hegenbart, Christian Haupt:

VARIATION OF THE AL PROTEIN PRIMARY STRUCTURE IN TWO CLINICAL VARIANTS OF AL AMYLOIDOSIS

www.klinikum.uni-heidelberg.de/zentrum-fuer-innere-medizin-medizin-klinik/innere-medizin-v-haematologie-onkologie-und-rheumatologie/behandlungsspektrum/haematologie/amyloidose

www.uni-ulm.de/en/nawi/nawi-pbc/research/protein-biotechnology/

Subproject 3:

Johannes Buchner:

DISSECTION OF THE MOLECULAR FIBRIL FORMATION PATHWAY OF PATIENT-DERIVED LIGHT CHAIN VARIANTS

https://www.department.ch.tum.de/biotech/startseite/

Subproject 4:

Bernd Reif:

CONFORMATIONAL DYNAMICS AND MISFOLDING OF THE FIBRIL PRECURSOR PROTEINS STUDIED BY NMR

https://www.department.ch.tum.de/ocb/home/

Subproject 5:

Marcus Fändrich:

CRYO-EM STRUCTURES OF AL AMYLOID FIBRILS FROM HUMAN HEART

www.uni-ulm.de/en/nawi/nawi-pbc/research/systemic-amyloidosis/

Subproject 6:

Christoph Röcken, Kerstin Amann:

ANALYSIS OF THE PATHOLOGICAL EFFECTS OF LIGHT CHAINS AND AL PROTEIN STATES

www.patho.uni-kiel.de/institut/