Selected Publications

Winokurow N, Schumacher S. (2019) A role for polysystin-1 and polycystin-2 in neural progenitor cell differentiation Cell Mol Life Sci. 2019 Jul;76(14):2851-2869. doi: 10.1007/s00018-019-03072-x.

Prozorovski T, Ingwers J, Lukas D, Götze P, Koop B, Graf J, Schneider R, Franke K, Schumacher S, Britsch S, Hartung HP, Kürt P, Berndt C, Aktas O. (2019) Regulation of sirtuin expression in autoimmune neuroinflammation: Induction of SIRT1 in oligodendrocyte progenitor cells Neuroscience Letters, jneulet.2019.04.007.

Schulz J, Schumacher S. (2018) Methods to Study the Roles of Rho GTPases in Dendritic Tree Complexity. Methods Mol Biol, 2018; 1821:297-317. doi:10.1007/978-1-4939-8612-5_21

Schulz J, Franke K, Frick M, Schumacher S (2016) Different roles of the small GTPases Rac1, Cdc42, and RhoG in CALEB/NGC-induced dendritic tree complexity.  J Neurochem, 139 (1):26-39. doi:10.1111

Franke K, Otto W, Johannes S, Baumgart J, Nitsch R, Schumacher S (2012) miR-124-regulated RhoG reduces neuronal process complexity via ELMO/Dock180/Rac1 and Cdc42 signaling. EMBO J 31: 2908-2921.

Brandt N, Franke K, Buck F, Harder S, Hassel B, Nitsch R, Schumacher S (2008) B56beta, a regulatory subunit of protein phosphatase 2A, interacts with CALEB/NGC and inhibits CALEB/NGC-mediated dendritic branching. FASEB J 22: 2521-2533.

Brandt N, Franke K, Rasin MR, Baumgart J, Vogt J, Khrulev S, Hassel B, Pohl EE, Sestan N, Nitsch R, Schumacher S (2007) The neural EGF family member CALEB/NGC mediates dendritic tree and spine complexity. EMBO J 26:2371-2386.

Hassel B, Schreff M, Stübe EM, Blaich U, Schumacher S (2003) CALEB Interacts with the Golgi-Associated Protein PIST. J Biol Chem 278: 40136-40143

Mauch DH, Nagler K, Schumacher S, Goritz C, Müller EC, Otto A, Pfrieger FW (2001) CNS synaptogenesis promoted by glia-derived cholesterol. Science 294: 1354-1357.

Schumacher S, Jung M, Nörenberg U, Dorner A, Chiquet-Ehrismann R, Stuermer CA, Rathjen FG (2001) CALEB binds via its acidic stretch to the fibrinogen-like domain of tenascin-C or tenascin-R and its expression is dynamically regulated after optic nerve lesion. J Biol Chem 276: 7337-7345.

Schumacher S, Volkmer H, Buck F, Otto A, Tarnok A, Roth S, Rathjen FG (1997) Chicken acidic leucine-rich EGF-like domain containing brain protein (CALEB), a neural member of the EGF family of differentiation factors, is implicated in neurite formation. J Cell Biol 136: 895-906.