Original publications

Hessel Honkoop, Dennis EM de Bakker, Alla Aharonov, Fabian Kruse, Avraham Shakked, Phong D Nguyen, Cecilia de Heus, Laurence Garric, Mauro J Muraro, Adam Shoffner, Federico Tessadori, Joshua Craiger Peterson, Wendy Noort, Alberto Bertozzi, Gilbert Weidinger, George Posthuma, Dominic Grun, Willem J van der Laarse, Judith Klumperman, Richard T Jaspers, Kenneth D Poss, Alexander van Oudenaarden, Eldad Tzahor, Jeroen Bakkers (2019) Single-cell analysis uncovers that metabolic reprogramming by ErbB2 signaling is essential for cardiomyocyte proliferation in the regenerating heart. eLife 8: e50163. doiI: 10.7554/eLife.50163.

Schneider A, Kühl M, Kühl SJ (2019) Longitudinal curriculum development: gradual optimizing of a biochemistry seminar, GMS J. Med. Educ., in press

Burczyk MS, Burkhalter MD, Tena TC, Grisanti LA, Kauk M, Matysik S, Donow C, Kustermann M, Rothe M, Cui Y, Raad F, Laue S, Moretti A, Zimmermann WH, Wess J, Kühl M, Hoffmann C, Tilley DG, Philipp M (2919) Muscarinic receptors promote pacemaker fate at the expense of secondary conduction system tissue in zebrafish. JCI Insight, 17:4(20)

Dannheisig DP, Beck E, Calzia E, Walther P, Behrends C, Pfister AS (2019) Loss of Peter Pan (PPAN) affects mitocondrial homeostasis and autophagic flux, Cells, 8: 894

Halder S, Torrecilla I, Burkhalter MD, Popović M, Fielden J, Vaz B, Oehler J, Pilger D, Lessel D, Wiseman K, Singh AN, Vendrell I, Fischer R, Philipp M, Ramadan K. (2019) SPRTN protease and checkpoint kinase 1 cross-activation loop safeguards DNA replication. Nat Commun. 2019;10(1):3142

Burkhalter MD, Sridhar A, Sampaio P, Jacinto R, Burczyk MS, Donow C, Angenendt M, Competence Network for Congenital Heart Defects Investigators, Hempel M, Walther P, Pennekamp P, Omran H, Lopes SS, Ware SM*, Philipp M* (2019) Imbalanced mitochondrial function provokes heterotaxy via aberrant ciliogenesis. J Clin Invest. 2019;130:2841-2855. * co-corresponding    

Schneider A, Kühl M, Kühl SJ (2019) Utilizing research findings in medical education: The testing effect within a flipped/inverted biochemistry classroom, Med. Teacher, 41:1245-51

Kühl SJ, Schneider A, Kestler HA, Toberer M, Kühl M, Fischer MR (2019) Investigating the self-study phase of an inverted biochemistry classroom - collaborative dyadic learning makes the difference, BMC Med. Educ., 28;19(1):64

Guo Y, DornT, Kühl SJ, Linnemann A, Rothe M, Pfister AS, Vainio S, Laugwitz KL, Moretti A, Kühl M (2019) The wnt inhibitor Dkk1 is required for maintaining the normal cardiac differentiation programm in Xenopus laevis, Dev. Biol., in press

Groß A*, Kracher B*, Kraus JM, Kühlwein SD, Pfister AS, Wiese S, Luckert K, Pötz O, Joos T, Van Daele D, De Raedt L, Kühl M, Kestler HA (2019) Representing dynamic biological networks with multi-scale probabilistic models, Commun. Biol. 17:21 * equal contribution

Maerz LD, Burkhalter MD, Schilpp C, Wittekindt OH, Frick M, Philipp M (2019) Pharmacological cholesterol depletion disturbs ciliogenesis and ciliary function in developing zebrafish. Commun Biol. 2:31. doi: 10.1038/s42003-018-0272-7

Maerz LD*, Casar Tena T*, Gerhards J, Donow C, Jeggo PA, Philipp M (2019) Analysis of cilia dysfunction phenotypes in zebrafish embryos depleted of origin recognition complex factors. Eur J Hum Genet. doi: 10.1038/s41431-019-0338-0. * equal contribution

Keil M, Meyer MT, Dannheisig DP, Maerz LD, Philipp M., Pfister AS (2019) Loss of Peter Pan protein is associated with cell cycle defects and apoptotic events. Biochim Biophys Acta Mol Cell Res. pii: S0167-4889(18)30377-X. doi: 10.1016/j.bbamcr.2019.01.010

Zawerton A, Yao B, Yeager JP, Pippucci T, Haseeb A, Smith JD, Wischmann L, Kühl SJ, Dean JCS, Pilz DT, Holder SE, McNeill A, Graziano C, Lefebvre V (2018) De novo SXO4 variants cause a neurodevelopmental disease associated with mild dysmorphism, Am. J. Hum. Genet., 104:246-59


Pfister AS (2019) Emerging role of the nucleolar stress response in autophagy, Front. Cell. Neurosci., accepted