About us

At the Institute of Biophysics, we are looking at the dynamics and mechano-chemical function of individual molecules and their interactions and transport processes inside of living cells with the aim of increasing the mechanistic understanding of important biological processes including gene expression, DNA repair and chromatin organization.

For this task, we are developing novel methodologies in an interdisciplinary approach between Physics, Biology and Data Sciences, including single-molecule FRET, single-molecule microscopy in living cells, super-resolution optical microscopy and single-molecule force spectroscopy. In addition, we are developing data analysis methods to foster a quantitative understanding of biological processes.  



Prof. Dr. Jens Michaelis
Prof. Dr. Christof Gebhardt



Publication March 2022
Andreas Große-Berkenbusch and Christof M. Gebhardt
Myosin VI regulates the spatial organisation of mammalian transcription initiation

February 2022
Congratulations on successfully defended doctoral thesis to Uwe Jantzen and Johannes Hettich!

Publication January 2022
Johannes Hettich and Christof M. Gebhardt
Periodic synchronization of isolated network elements facilitates simulating and inferring gene regulatory networks including stochastic molecular kinetics