C04 – Fluorescent nanodiamonds as biocompatible markers and sensors for simultaneous peptide delivery and bioimaging (Fedor Jelezko, Yuzhou Wu)

One important prerequisite for the development of effective peptide drug delivery systems is the possibility to monitor the entire process of drug administration and subsequent trafficking in real time. To achieve this, the present project will couple fluorescent nanodiamonds (FNDs) to antimicrobial and antineoplastic peptides examined within the CRC. FNDs are non-toxic and offer long-lasting emission at near infrared wavelengths. Thus, they represent a highly promising tool to monitor trafficking and target interactions of peptide drugs over extended time periods, which is a key step towards rationalization and improvement of drug delivery.

 

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Principal Investigators

Jelezko, Fedor, Prof. Dr.

Institute of Quantum Optics
Ulm University
Albert Einstein Allee 11
89081 Ulm
0731 50 23750
fedor.jelezko(at)uni-ulm.de