C03 – Mesoporous silica micro- and nanoparticles for controlled release of peptide drugs (Mika Lindén)

Mesoporous silica particles (MSNs) represent a versatile category of nanocarriers for peptide delivery. They shield peptides against proteolytic degradation and can be functionalized for cell type- or organ-specific targeting. Furthermore, MSNs can be linked to imaging moieties, such as fluorescence markers, for convenient in vivo monitoring. The present project will thus exploit MSNs to improve the delivery, stability, specificity and release of antimicrobial and anticancer peptides and to introduce labels to monitor their biodistribution in organisms.

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Principal Investigators

Lindén, Mika, Prof. Dr.

Institute of Inorganic Chemistry II
Ulm University
Albert-Einstein-Allee 11
89081 Ulm
Tel: 0731 5022730