Zusammenstellung von Bildern aus dem Sonderforschungsbereich

2021

194.
S. Hug, S. Bernhard, A. E. P. Stratmann, M. Erber, L. Wohlgemuth, C. L. Knapp, J. M. Bauer, L. Vidoni, M. Fauler, K. J. Föhr, P. Radermacher, A. Hoffmann, M. Huber-Lang and D. A. C. Messerer, "Activation of Neutrophil Granulocytes by Platelet-Activating Factor Is Impaired During Experimental Sepsis" , Frontiers in Immunology, vol. 12, 2021.
DOI:10.3389/fimmu.2021.642867
193.
D. A. C. Messerer, M. Fauler, A. Horneffer, A. Schneider, O. Keis, L. M. Mauder and P. Radermacher, "Do medical students recognise the deteriorating patient by analysing their vital signs? A monocentric observational study based on the National Early Warning Score 2" , BMJ Open, vol. 11, no. 2, pp. e044354, 2021.
DOI:10.1136/bmjopen-2020-044354
Datei:https://www.ncbi.nlm.nih.gov/pubmed/33622952
192.
B. Weber, I. Lackner, M. Baur, F. Gebhard, R. Pfeifer, P. Cinelli, S. Halvachizadeh, M. Teuben, H. C. Pape, A. Imhof, M. Lipiski, N. Cesarovic and M. Kalbitz, "Early myocardial damage (EMD) and valvular insufficiency result in impaired cardiac function after multiple trauma in pigs" , Sci Rep, vol. 11, no. 1, pp. 1151, 2021.
DOI:10.1038/s41598-020-80409-8
Datei:https://www.ncbi.nlm.nih.gov/pubmed/33441945
191.
K. Luntzer, I. Lackner, B. Weber, Y. Mödinger, A. Ignatius, F. Gebhard, S. Mihaljevic, M. Haffner-Luntzer and M. Kalbitz, "Increased Presence of Complement Factors and Mast Cells in Alveolar Bone and Tooth Resorption" , International Journal of Molecular Sciences, vol. 22, no. 5, 2021.
DOI:10.3390/ijms22052759
190.
I. Lackner, B. Weber, M. Haffner-Luntzer, S. Hristova, F. Gebhard, C. Lam, K. Morioka, R. S. Marcucio, T. Miclau and M. Kalbitz, "Systemic and local cardiac inflammation after experimental long bone fracture, traumatic brain injury and combined trauma in mice" , J Orthop Translat, vol. 28, pp. 39-46, 2021.
DOI:10.1016/j.jot.2020.12.003
Datei:https://www.ncbi.nlm.nih.gov/pubmed/33717980
189.
M. Landenberger, J. Nieland, M. Roeder, K. Norgaard, P. Papatheodorou, K. Ernst and H. Barth, "The cytotoxic effect of Clostridioides difficile pore-forming toxin CDTb" , Biochim Biophys Acta Biomembr, vol. 1863, no. 6, pp. 183603, 2021.
DOI:10.1016/j.bbamem.2021.183603
Datei:https://www.ncbi.nlm.nih.gov/pubmed/33689753
188.
B. Trautwein, T. Merz, N. Denoix, C. Szabó, E. Calzia, P. Radermacher and O. McCook, "DeltaMST and the Regulation of Cardiac CSE and OTR Expression in Trauma and Hemorrhage" , Antioxidants (Basel), vol. 10, no. 2, 2021.
DOI:10.3390/antiox10020233
Datei:https://www.ncbi.nlm.nih.gov/pubmed/33546491

2020

187.
D. A. C. Messerer, R. Halbgebauer, B. Nilsson, H. Pavenstadt, P. Radermacher and M. Huber-Lang, "Immunopathophysiology of trauma-related acute kidney injury" , Nat Rev Nephrol, 2020.
DOI:10.1038/s41581-020-00344-9
Datei:https://www.ncbi.nlm.nih.gov/pubmed/32958893
186.
M. Fellermann, F. Wondany, S. Carle, J. Nemeth, T. Sadhanasatish, M. Frick, H. Barth and J. Michaelis, "Super-resolution microscopy unveils transmembrane domain-mediated internalization of cross-reacting material 197 into diphtheria toxin-resistant mouse J774A.1 cells and primary rat fibroblasts in vitro" , Arch Toxicol, vol. 94, no. 5, pp. 1753-1761, 2020.
DOI:10.1007/s00204-020-02731-4
Datei:https://www.ncbi.nlm.nih.gov/pubmed/32266418

2019

185.
M. Gröger, M. Wepler, U. Wachter, T. Merz, O. McCook, S. Kress, B. Lukaschewski, M. Huber-Lang, E. Calzia, M. Georgieff, N. Nagahara, C. Szabó, P. Radermacher and C. Hartmann, "The Effects of Genetic 3-Mercaptopyruvate Sulfurtransferase Deficiency in Murine Traumatic-Hemorrhagic Shock" , Shock, vol. 51, no. 4, pp. 472-478, 2019.
DOI:10.1097/SHK.0000000000001165
Datei:https://www.ncbi.nlm.nih.gov/pubmed/29668565
184.
M. Wepler, T. Merz, U. Wachter, J. Vogt, E. Calzia, A. Scheuerle, P. Möller, M. Gröger, S. Kress, M. Fink, B. Lukaschewski, G. Rumm, B. Stahl, M. Georgieff, M. Huber-Lang, R. Torregrossa, M. Whiteman, O. McCook, P. Radermacher and C. Hartmann, "The Mitochondria-Targeted H2S-Donor AP39 in a Murine Model of Combined Hemorrhagic Shock and Blunt Chest Trauma" , Shock, vol. 52, no. 2, pp. 230-239, 2019.
DOI:10.1097/SHK.0000000000001210
Datei:https://www.ncbi.nlm.nih.gov/pubmed/29927788
183.
C. Hartmann, M. Gröger, J. P. Noirhomme, A. Scheuerle, P. Möller, U. Wachter, M. Huber-Lang, B. Nußbaum, B. Jung, T. Merz, O. McCook, S. Kress, B. Stahl, E. Calzia, M. Georgieff, P. Radermacher and M. Wepler, "In-Depth Characterization of the Effects of Cigarette Smoke Exposure on the Acute Trauma Response and Hemorrhage in Mice" , Shock, vol. 51, no. 1, pp. 68-77, 2019.
DOI:10.1097/SHK.0000000000001115
Datei:https://www.ncbi.nlm.nih.gov/pubmed/29424792
182.
A. J. Heck, T. Ostertag, L. Schnell, S. Fischer, B. K. Agrawalla, P. Winterwerber, E. Wirsching, M. Fauler and M. Frick, "Supramolecular Toxin Complexes for Targeted Pharmacological Modulation of Polymorphonuclear Leukocyte Functions" , Adv Healthc Mater, pp. e1900665, 2019.
DOI:10.1002/adhm.201900665
Datei:https://www.ncbi.nlm.nih.gov/pubmed/31318180
181.
M. Wepler, J. M. Preuss, T. Merz, C. Hartmann, U. Wachter, O. McCook, J. Vogt, S. Kress, M. Gröger, M. Fink, A. Scheuerle, P. Möller, E. Calzia, U. Burret, P. Radermacher, J. P. Tuckermann and S. Vettorazzi, "Impaired Glucocorticoid Receptor Dimerization Aggravates LPS-Induced Circulatory and Pulmonary Dysfunction" , Front Immunol, vol. 10, pp. 3152, 2019.
DOI:10.3389/fimmu.2019.03152
Datei:https://www.ncbi.nlm.nih.gov/pubmed/32038649
180.
D. Langgartner, U. Wachter, C. Hartmann, M. Gröger, J. Vogt, T. Merz, O. McCook, M. Fink, S. Kress, M. Georgieff, J. F. Kunze, P. L. Radermacher, S. O. Reber and M. Wepler, "Effects of Psychosocial Stress on Subsequent Hemorrhagic Shock and Resuscitation in Male Mice" , Shock, vol. 51, no. 6, pp. 725-730, 2019.
DOI:10.1097/SHK.0000000000001204
Datei:https://www.ncbi.nlm.nih.gov/pubmed/29889818

2018

179.
A. Ignatius and J. Tuckermann, "New horizons for osteoanabolic treatment?" , Nat Rev Endocrinol, vol. 14, no. 9, pp. 508-509, 2018.
DOI:10.1038/s41574-018-0069-2
Datei:https://www.ncbi.nlm.nih.gov/pubmed/30050157
178.
J. Demiselle, M. Wepler, C. Hartmann, P. Radermacher, F. Schortgen, F. Meziani, M. Singer, V. Seegers, P. Asfar and H. S. investigators, "Hyperoxia toxicity in septic shock patients according to the Sepsis-3 criteria: a post hoc analysis of the HYPER2S trial" , Ann Intensive Care, vol. 8, no. 1, pp. 90, 2018.
DOI:10.1186/s13613-018-0435-1
Datei:https://www.ncbi.nlm.nih.gov/pubmed/30225670
177.
M. Mettang, S. N. Reichel, M. Lattke, A. Palmer, A. Abaei, V. Rasche, M. Huber-Lang, B. Baumann and T. Wirth, "IKK2/NF-kappaB signaling protects neurons after traumatic brain injury" , FASEB J, vol. 32, no. 4, pp. 1916-1932, 2018.
DOI:10.1096/fj.201700826R
Datei:https://www.ncbi.nlm.nih.gov/pubmed/29187362
176.
A. E. Rapp, Y. Hachemi, J. Kemmler, M. Koenen, J. Tuckermann and A. Ignatius, "Induced global deletion of glucocorticoid receptor impairs fracture healing" , FASEB J, vol. 32, no. 4, pp. 2235-2245, 2018.
DOI:10.1096/fj.201700459RR
Datei:https://www.ncbi.nlm.nih.gov/pubmed/29217668
175.
T. Merz, B. Lukaschewski, D. Wigger, A. Rupprecht, M. Wepler, M. Gröger, C. Hartmann, M. Whiteman, C. Szabó, R. Wang, C. Waller, P. Radermacher and O. McCook, "Interaction of the hydrogen sulfide system with the oxytocin system in the injured mouse heart" , Intensive Care Med Exp, vol. 6, no. 1, pp. 41, 2018.
DOI:10.1186/s40635-018-0207-0
Datei:https://www.ncbi.nlm.nih.gov/pubmed/30341744
174.
T. S. Böbel, S. B. Hackl, D. Langgartner, M. N. Jarczok, N. Rohleder, G. A. Rook, C. A. Lowry, H. Gundel, C. Waller and S. O. Reber, "Less immune activation following social stress in rural vs. urban participants raised with regular or no animal contact, respectively" , Proc Natl Acad Sci U S A, vol. 115, no. 20, pp. 5259-5264, 2018.
DOI:10.1073/pnas.1719866115
Datei:https://www.ncbi.nlm.nih.gov/pubmed/29712842
173.
M. F. Osuchowski, A. Ayala, S. Bahrami, M. Bauer, M. Boros, J. M. Cavaillon, I. H. Chaudry, C. M. Coopersmith, C. Deutschman, S. Drechsler, P. Efron, C. Frostell, G. Fritsch, W. Gozdzik, J. Hellman, M. Huber-Lang, S. Inoue, S. Knapp, A. V. Kozlov, C. Libert, J. C. Marshall, L. L. Moldawer, P. Radermacher, H. Redl, D. G. Remick, M. Singer, C. Thiemermann, P. Wang, W. J. Wiersinga, X. Xiao and B. Zingarelli, "Minimum quality threshold in pre-clinical sepsis studies (MQTiPSS): an international expert consensus initiative for improvement of animal modeling in sepsis" , Intensive Care Med Exp, vol. 6, no. 1, pp. 26, 2018.
DOI:10.1186/s40635-018-0189-y
Datei:https://www.ncbi.nlm.nih.gov/pubmed/30112605
172.
Y. Hachemi, A. E. Rapp, A. K. Picke, G. Weidinger, A. Ignatius and J. Tuckermann, "Molecular mechanisms of glucocorticoids on skeleton and bone regeneration after fracture" , J Mol Endocrinol, vol. 61, no. 1, pp. R75-R90, 2018.
DOI:10.1530/JME-18-0024
Datei:https://www.ncbi.nlm.nih.gov/pubmed/29588427
171.
A. K. Picke, G. M. Campbell, M. Blüher, U. Krügel, F. N. Schmidt, E. Tsourdi, M. Winzer, M. Rauner, V. Vukicevic, B. Busse, J. Salbach-Hirsch, J. P. Tuckermann, J. C. Simon, U. Anderegg, L. C. Hofbauer and A. Saalbach, "Thy-1 (CD90) promotes bone formation and protects against obesity" , Sci Transl Med, vol. 10, no. 453, 2018.
DOI:10.1126/scitranslmed.aao6806
Datei:https://www.ncbi.nlm.nih.gov/pubmed/30089635
170.
F. Seichter, E. Tütüncü, L. T. Hagemann, J. Vogt, U. Wachter, M. Gröger, S. Kress, P. Radermacher and B. Mizaikoff, "Online monitoring of carbon dioxide and oxygen in exhaled mouse breath via substrate-integrated hollow waveguide Fourier-transform infrared-luminescence spectroscopy" , J Breath Res, vol. 12, no. 3, pp. 036018, 2018.
DOI:10.1088/1752-7163/aabf98
Datei:https://www.ncbi.nlm.nih.gov/pubmed/29674598