Ausgewählte Publikationen

  1. Rapp, A. E., Y. Hachemi, J. Kemmler, M. Koenen, J. Tuckermann et al., 2018 (2017 in press) Induced global deletion of glucocorticoid receptor impairs fracture healing. FASEB J.
  2. Prystaz, K., K. Kaiser, A. Kovtun, M. Haffner-Luntzer, V. Fischer et al., 2018 (2017 in press) Distinct effects of interleukin-6 classic and trans-signaling in bone fracture healing. Am J Pathol.
  3. Wiesner, D., L. Tar, B. Linkus, A. Chandrasekar, F. Olde Heuvel et al., 2018 Reversible induction of TDP-43 granules in cortical neurons after traumatic injury. Exp Neurol 299: 15-25.
  4. Denk, S., S. Weckbach, P. Eisele, C. K. Braun, R. Wiegner et al., 2018 Role of Hemorrhagic Shock in Experimental Polytrauma. Shock 49: 154-163.
  5. Amann, E. M., M. T. Rojewski, S. Rodi, D. Fürst, J. Fiedler et al., 2018 Systemic recovery and therapeutic effects of transplanted allogenic and xenogenic mesenchymal stromal cells in a rat blunt chest trauma model, pp. 218-231 in Cytotherapy.
  6. Zimprich, A., G. Mroz, C. Meyer Zu Reckendorf, S. Anastasiadou, P. Forstner et al., 2017 Serum Response Factor (SRF) Ablation Interferes with Acute Stress-Associated Immediate and Long-Term Coping Mechanisms. Mol Neurobiol 54: 8242-8262.
  7. Wrba, L., A. Palmer, C. K. Braun and M. Huber-Lang, 2017 Evaluation of gut-blood barrier dysfunction in various models of trauma, hemorrhagic shock, and burn injury. J Trauma Acute Care Surg 83: 944-953.
  8. Wehner, D., T. M. Tsarouchas, A. Michael, C. Haase, G. Weidinger et al., 2017 Wnt signaling controls pro-regenerative Collagen XII in functional spinal cord regeneration in zebrafish. Nat Commun 8: 126.
  9. Wanner, R., M. Gey, A. Abaei, D. Warnecke, L. de Roy et al., 2017 Functional and Molecular Characterization of a Novel Traumatic Peripheral Nerve-Muscle Injury Model. Neuromolecular Med 19: 357-374.
  10. Thielecke, L., T. Aranyossy, A. Dahl, R. Tiwari, I. Roeder et al., 2017 Limitations and challenges of genetic barcode quantification. Sci Rep 7: 43249.
  11. Singh, K., L. Krug, A. Basu, P. Meyer, N. Treiber et al., 2017 Alpha-Ketoglutarate Curbs Differentiation and Induces Cell Death in Mesenchymal Stromal Precursors with Mitochondrial Dysfunction. Stem Cells 35: 1704-1718.
  12. Seichter, F., J. Vogt, P. Radermacher and B. Mizaikoff, 2017 Nonlinear calibration transfer based on hierarchical Bayesian models and Lagrange Multipliers: Error bounds of estimates via Monte Carlo - Markov Chain sampling. Anal Chim Acta 951: 32-45.
  13. Seichter, F., J. Vogt, P. Radermacher and B. Mizaikoff, 2017 Response-surface fits and calibration transfer for the correction of the oxygen effect in the quantification of carbon dioxide via FTIR spectroscopy. Anal Chim Acta 972: 16-27.
  14. Pfaender, S., A. K. Sauer, S. Hagmeyer, K. Mangus, L. Linta et al., 2017 Zinc deficiency and low enterocyte zinc transporter expression in human patients with autism related mutations in SHANK3. Sci Rep 7: 45190.
  15. Nussbaum, B. L., T. Stenzel, T. Merz, A. Scheuerle, O. McCook et al., 2017 Hyperoxia or Therapeutic Hypothermia During Resuscitation from Non-Lethal Hemorrhagic Shock in Swine. Shock 48: 564-570.
  16. Mettang, M., S. N. Reichel, M. Lattke, A. Palmer, A. Abaei et al., 2017 IKK2/NF-kappaB signaling protects neurons after traumatic brain injury. FASEB J.
  17. Merz, T., J. A. Vogt, U. Wachter, E. Calzia, C. Szabo et al., 2017 Impact of hyperglycemia on cystathionine-gamma-lyase expression during resuscitated murine septic shock. Intensive Care Med Exp 5: 30.
  18. Martin, T., A. Moglich, I. Felix, C. Fortsch, A. Rittlinger et al., 2017 Rho-inhibiting C2IN-C3 fusion toxin inhibits chemotactic recruitment of human monocytes ex vivo and in mice in vivo. Arch Toxicol.
  19. Magadum, A., Y. Ding, L. He, T. Kim, M. D. Vasudevarao et al., 2017 Live cell screening platform identifies PPARdelta as a regulator of cardiomyocyte proliferation and cardiac repair. Cell Res 27: 1002-1019.
  20. Liu, P., S. Lee, J. Knoll, A. Rauch, S. Ostermay et al., 2017 Loss of menin in osteoblast lineage affects osteocyte-osteoclast crosstalk causing osteoporosis. Cell Death Differ 24: 672-682.
  21. Lee, S., P. Liu, R. Teinturier, J. Jakob, M. Tschaffon et al., 2017 Deletion of Menin in craniofacial osteogenic cells in mice elicits development of mandibular ossifying fibroma. Oncogene.
  22. Lattke, M., S. N. Reichel, A. Magnutzki, A. Abaei, V. Rasche et al., 2017 Transient IKK2 activation in astrocytes initiates selective non-cell-autonomous neurodegeneration. Mol Neurodegener 12: 16.
  23. Langgartner, D., D. Peterlik, S. Foertsch, A. M. Fuchsl, P. Brokmann et al., 2017 Individual differences in stress vulnerability: The role of gut pathobionts in stress-induced colitis. Brain Behav Immun 64: 23-32.
  24. Kroner, J., A. Kovtun, J. Kemmler, J. J. Messmann, G. Strauss et al., 2017 Mast cells are critical regulators of bone fracture-induced inflammation and osteoclast formation and activity. J Bone Miner Res 32: 2431–2444.
  25. Kreidler, A. M., R. Benz and H. Barth, 2017 Chloroquine derivatives block the translocation pores and inhibit cellular entry of Clostridium botulinum C2 toxin and Bacillus anthracis lethal toxin. Arch Toxicol 91: 1431-1445.
  26. Kovtun, A., S. Bergdolt, Y. Hagele, R. Matthes, J. D. Lambris et al., 2017 Complement receptors C5aR1 and C5aR2 act differentially during the early immune response after bone fracture but are similarly involved in bone repair. Sci Rep 7: 14061.
  27. Kalbitz, M., J. Pressmar, J. Stecher, B. Weber, M. Weiss et al., 2017 The Role of Troponin in Blunt Cardiac Injury After Multiple Trauma in Humans. World J Surg 41: 162-169.
  28. Kalbitz, M., E. M. Amann, B. Bosch, A. Palmer, A. Schultze et al., 2017 Experimental blunt chest trauma-induced myocardial inflammation and alteration of gap-junction protein connexin 43. PLoS One 12: e0187270.
  29. Itkin, T., A. Kumari, E. Schneider, S. Gur-Cohen, C. Ludwig et al., 2017 MicroRNA-155 promotes G-CSF-induced mobilization of murine hematopoietic stem and progenitor cells via propagation of CXCL12 signaling. Leukemia 31: 1247-1250.
  30. Husecken, Y., S. Muche, M. Kustermann, M. Klingspor, A. Palmer et al., 2017 MDSCs are induced after experimental blunt chest trauma and subsequently alter antigen-specific T cell responses. Sci Rep 7: 12808.
  31. Huber-Lang, M., K. N. Ekdahl, R. Wiegner, K. Fromell and B. Nilsson, 2017 Auxiliary activation of the complement system and its importance for the pathophysiology of clinical conditions. Semin Immunopathol.
  32. Hartmann, C., P. Radermacher, M. Wepler and B. Nubaum, 2017 Non-Hemodynamic Effects of Catecholamines. Shock.
  33. Hartmann, C., M. Loconte, E. Antonucci, M. Holzhauser, T. Holle et al., 2017 Effects of Hyperoxia During Resuscitation From Hemorrhagic Shock in Swine With Preexisting Coronary Artery Disease. Crit Care Med 45: e1270-e1279.
  34. Hartmann, C., S. Hafner, A. Scheuerle, P. Moller, M. Huber-Lang et al., 2017 The Role of Cystathionine-gamma-Lyase In Blunt Chest Trauma in Cigarette Smoke Exposed Mice. Shock 47: 491-499.
  35. Halbgebauer, R., C. K. Braun, S. Denk, B. Mayer, P. Cinelli et al., 2017 Hemorrhagic shock drives glycocalyx, barrier and organ dysfunction early after polytrauma. J Crit Care 44: 229-237.
  36. Hagemeyer, N., K. M. Hanft, M. A. Akriditou, N. Unger, E. S. Park et al., 2017 Microglia contribute to normal myelinogenesis and to oligodendrocyte progenitor maintenance during adulthood. Acta Neuropathol 134: 441-458.
  37. Hafner, S., K. Wagner, S. Weber, M. Groger, M. Wepler et al., 2017 Role of the Purinergic Receptor P2XR4 After Blunt Chest Trauma in Cigarette Smoke-Exposed Mice. Shock 47: 193-199.
  38. Haffner-Luntzer, M., F. Muller-Graf, R. Matthys, Y. Hägele, V. Fischer et al., 2017 Evaluation of high-resolution In Vivo MRI for longitudinal analysis of endochondral fracture healing in mice. PLoS One 12: e0174283.
  39. Haffner-Luntzer, M., F. Müller-Graf, R. Matthys, A. Abaei, R. Jonas et al., 2017 In Vivo Evaluation of Fracture Callus Development During Bone Healing in Mice Using an MRI-compatible Osteosynthesis Device for the Mouse Femur. J Vis Exp: e56679.
  40. Haffner-Luntzer, M., V. Fischer, K. Prystaz, A. Liedert and A. Ignatius, 2017 The inflammatory phase of fracture healing is influenced by oestrogen status in mice. Eur J Med Res 33: 23.
  41. Guidi, N., M. Sacma, L. Standker, K. Soller, G. Marka et al., 2017 Osteopontin attenuates aging-associated phenotypes of hematopoietic stem cells. EMBO J 36: 1463.
  42. Gačanin, J., A. Kovtun, S. Fischer, V. Schwager, J. Quambusch et al., 2017 Spatiotemporally Controlled Release of Rho-Inhibiting C3 Toxin from a Protein–DNA Hybrid Hydrogel for Targeted Inhibition of Osteoclast Formation and Activity. Adv Healthc Mater 6: 1700392.
  43. Fois, G., V. E. Winkelmann, L. Bareis, L. Staudenmaier, E. Hecht et al., 2017 ATP is stored in lamellar bodies to activate vesicular P2X4 in an autocrine fashion upon exocytosis. J Gen Physiol.
  44. Foertsch, S., M. Haffner-Luntzer, J. Kroner, F. Gross, K. Kaiser et al., 2017 Chronic psychosocial stress disturbs long-bone growth in adolescent mice. Dis Model Mech 10: 1399-1409.
  45. Foertsch, S., A. M. Fuchsl, S. D. Faller, H. Holzer, D. Langgartner et al., 2017 Splenic glucocorticoid resistance following psychosocial stress requires physical injury. Sci Rep 7: 15730.
  46. Fattahi, F., M. Kalbitz, E. A. Malan, E. Abe, L. Jajou et al., 2017 Complement-induced activation of MAPKs and Akt during sepsis: role in cardiac dysfunction. FASEB J 31: 4129-4139.
  47. Ernst, K., J. Schmid, M. Beck, M. Hagele, M. Hohwieler et al., 2017 Hsp70 facilitates trans-membrane transport of bacterial ADP-ribosylating toxins into the cytosol of mammalian cells. Sci Rep 7: 2724.
  48. Denk, S., R. P. Taylor, R. Wiegner, E. M. Cook, M. A. Lindorfer et al., 2017 Complement C5a-Induced Changes in Neutrophil Morphology During Inflammation. Scand J Immunol 86: 143-155.
  49. Denk, S., M. D. Neher, D. A. C. Messerer, R. Wiegner, B. Nilsson et al., 2017 Complement C5a Functions as a Master Switch for the pH Balance in Neutrophils Exerting Fundamental Immunometabolic Effects. J Immunol 198: 4846-4854.
  50. Confalonieri, M., F. Salton and F. Fabiano, 2017 Acute respiratory distress syndrome. Eur Respir Rev 26.
  51. Chandrasekar, A., F. O. Heuvel, A. Palmer, B. Linkus, A. C. Ludolph et al., 2017 Acute ethanol administration results in a protective cytokine and neuroinflammatory profile in traumatic brain injury. Int Immunopharmacol 51: 66-75.
  52. Braun, C. K., M. Kalbitz, R. Halbgebauer, P. Eisele, D. A. C. Messerer et al., 2017 Early structural changes of the heart after experimental polytrauma and hemorrhagic shock. PLoS One 12: e0187327.
  53. Bonfanti, E., P. Gelosa, M. Fumagalli, L. Dimou, F. Vigano et al., 2017 The role of oligodendrocyte precursor cells expressing the GPR17 receptor in brain remodeling after stroke. Cell Death Dis 8: e2871.
  54. Bergdolt, S., A. Kovtun, Y. Hagele, A. Liedert, T. Schinke et al., 2017 Osteoblast-specific overexpression of complement receptor C5aR1 impairs fracture healing. PLoS One 12: e0179512.
  55. Asfar, P., F. Schortgen, J. Boisrame-Helms, J. Charpentier, E. Guerot et al., 2017 Hyperoxia and hypertonic saline in patients with septic shock (HYPERS2S): a two-by-two factorial, multicentre, randomised, clinical trial. Lancet Respir Med 5: 180-190.
  56. Wu, C. C., F. Kruse, M. D. Vasudevarao, J. P. Junker, D. C. Zebrowski et al., 2016 Spatially Resolved Genome-wide Transcriptional Profiling Identifies BMP Signaling as Essential Regulator of Zebrafish Cardiomyocyte Regeneration. Dev Cell 36: 36-49.
  57. Winkelmann VE, G. F., Hobi N, Dietl P, Frick M., 2016 Establishment of a co-culture to mimic the alveolar-capillary barrier in vitro, pp. S707. Acta Physiologica.
  58. Vigano, F., S. Schneider, M. Cimino, E. Bonfanti, P. Gelosa et al., 2016 GPR17 expressing NG2-Glia: Oligodendrocyte progenitors serving as a reserve pool after injury. Glia 64: 287-299.
  59. Stenzel, T., C. Weidgang, K. Wagner, F. Wagner, M. Groger et al., 2016 Association of Kidney Tissue Barrier Disrupture and Renal Dysfunction in Resuscitated Murine Septic Shock. Shock 46: 398-404.
  60. Sroka, R., J. Van Lint, S. F. Katz, M. R. Schneider, A. Kleger et al., 2016 Cortactin is a scaffolding platform for the E-cadherin adhesion complex and is regulated by protein kinase D1 phosphorylation. J Cell Sci 129: 2416-2429.
  61. Sinha, S., D. Hoshino, N. H. Hong, K. C. Kirkbride, N. E. Grega-Larson et al., 2016 Cortactin promotes exosome secretion by controlling branched actin dynamics. J Cell Biol 214: 197-213.
  62. Sehring, I. M., C. Jahn and G. Weidinger, 2016 Zebrafish fin and heart: what's special about regeneration? Curr Opin Genet Dev 40: 48-56.
  63. Schneider, S., A. Gruart, S. Grade, Y. Zhang, S. Kroger et al., 2016 Decrease in newly generated oligodendrocytes leads to motor dysfunctions and changed myelin structures that can be rescued by transplanted cells. Glia 64: 2201-2218.
  64. Schmidt, D., D. Peterlik, S. O. Reber, A. Lechner and D. N. Mannel, 2016 Induction of Suppressor Cells and Increased Tumor Growth following Chronic Psychosocial Stress in Male Mice. PLoS One 11: e0159059.
  65. Reber, S. O., P. H. Siebler, N. C. Donner, J. T. Morton, D. G. Smith et al., 2016 Immunization with a heat-killed preparation of the environmental bacterium Mycobacterium vaccae promotes stress resilience in mice. Proc Natl Acad Sci U S A 113: E3130-3139.
  66. Rapp, A. E., R. Bindl, S. Recknagel, A. Erbacher, I. Muller et al., 2016 Fracture Healing Is Delayed in Immunodeficient NOD/scidIL2Rgammacnull Mice. PLoS One 11: e0147465.
  67. Peter, S., M. M. Ten Brinke, J. Stedehouder, C. M. Reinelt, B. Wu et al., 2016 Dysfunctional cerebellar Purkinje cells contribute to autism-like behaviour in Shank2-deficient mice. Nat Commun 7: 12627.
  68. Masselink, W., N. J. Cole, F. Fenyes, S. Berger, C. Sonntag et al., 2016 A somitic contribution to the apical ectodermal ridge is essential for fin formation. Nature 535: 542-546.
  69. Liu, P., M. Baumgart, M. Groth, J. Wittmann, H. M. Jack et al., 2016 Dicer ablation in osteoblasts by Runx2 driven cre-loxP recombination affects bone integrity, but not glucocorticoid-induced suppression of bone formation. Sci Rep 6: 32112.
  70. Li, Y., L. Chang, Y. Song, X. Gao, F. Roselli et al., 2016 Astrocytic GluN2A and GluN2B Oppose the Synaptotoxic Effects of Amyloid-beta1-40 in Hippocampal Cells. J Alzheimers Dis 54: 135-148.
  71. Kovtun, A., S. Bergdolt, R. Wiegner, P. Radermacher, M. Huber-Lang et al., 2016 The crucial role of neutrophil granulocytes in bone fracture healing. Eur Cell Mater 32: 152-162.
  72. Knoller, E., T. Stenzel, F. Broeskamp, R. Hornung, A. Scheuerle et al., 2016 Effects of Hyperoxia and Mild Therapeutic Hypothermia During Resuscitation From Porcine Hemorrhagic Shock. Crit Care Med 44: e264-277.
  73. Kalbitz, M., F. Fattahi, T. J. Herron, J. J. Grailer, L. Jajou et al., 2016 Complement Destabilizes Cardiomyocyte Function In Vivo after Polymicrobial Sepsis and In Vitro. J Immunol 197: 2353-2361.
  74. Kalbitz, M., F. Fattahi, J. J. Grailer, L. Jajou, E. A. Malan et al., 2016 Complement-induced activation of the cardiac NLRP3 inflammasome in sepsis. FASEB J 30: 3997-4006.
  75. Jiang, D., J. Muschhammer, Y. Qi, A. Kugler, J. C. de Vries et al., 2016 Suppression of Neutrophil-Mediated Tissue Damage-A Novel Skill of Mesenchymal Stem Cells. Stem Cells 34: 2393-2406.
  76. Huber-Lang, M., F. Gebhard, C. Q. Schmidt, A. Palmer, S. Denk et al., 2016 Complement therapeutic strategies in trauma, hemorrhagic shock and systemic inflammation - closing Pandora's box? Semin Immunol 28: 278-284.
  77. Heise, C., J. C. Schroeder, M. Schoen, S. Halbedl, D. Reim et al., 2016 Selective Localization of Shanks to VGLUT1-Positive Excitatory Synapses in the Mouse Hippocampus. Front Cell Neurosci 10: 106.
  78. Hartmann, K., M. Koenen, S. Schauer, S. Wittig-Blaich, M. Ahmad et al., 2016 Molecular Actions of Glucocorticoids in Cartilage and Bone During Health, Disease, and Steroid Therapy. Physiol Rev 96: 409-447.
  79. Harder, M. J., M. Anliker, B. Hochsmann, T. Simmet, M. Huber-Lang et al., 2016 Comparative Analysis of Novel Complement-Targeted Inhibitors, MiniFH, and the Natural Regulators Factor H and Factor H-like Protein 1 Reveal Functional Determinants of Complement Regulation. J Immunol 196: 866-876.
  80. Halbedl, S., M. Schoen, M. S. Feiler, T. M. Boeckers and M. J. Schmeisser, 2016 Shank3 is localized in axons and presynaptic specializations of developing hippocampal neurons and involved in the modulation of NMDA receptor levels at axon terminals. J Neurochem 137: 26-32.
  81. Haffner-Luntzer, M., J. Kemmler, V. Heidler, K. Prystaz, T. Schinke et al., 2016 Inhibition of Midkine Augments Osteoporotic Fracture Healing. PLoS One 11: e0159278.
  82. Haffner-Luntzer, M., A. Heilmann, A. E. Rapp, R. Roessler, T. Schinke et al., 2016 Antagonizing Midkine Accelerates Fracture Healing in Mice by Enhanced Bone Formation in the Fracture Callus. Br J Pharmacol 173: 2237-2249.
  83. Gey, M., R. Wanner, C. Schilling, M. T. Pedro, D. Sinske et al., 2016 Atf3 mutant mice show reduced axon regeneration and impaired regeneration-associated gene induction after peripheral nerve injury. Open Biol 6.
  84. Falkner, S., S. Grade, L. Dimou, K. K. Conzelmann, T. Bonhoeffer et al., 2016 Transplanted embryonic neurons integrate into adult neocortical circuits. Nature 539: 248-253.
  85. Eiseler, T., C. Wille, C. Koehler, A. Illing and T. Seufferlein, 2016 Protein Kinase D2 Assembles a Multiprotein Complex at the Trans-Golgi Network to Regulate Matrix Metalloproteinase Secretion. J Biol Chem 291: 462-477.
  86. Ehrnthaller, C., M. Huber-Lang, A. Kovtun, A. E. Rapp, J. Kemmler et al., 2016 C5aR inhibition in the early inflammatory phase does not affect bone regeneration in a model of uneventful fracture healing. Eur J Med Res 21: 42.
  87. Anastasiadou, S., and B. Knoll, 2016 The multiple sclerosis drug fingolimod (FTY720) stimulates neuronal gene expression, axonal growth and regeneration. Exp Neurol 279: 243-260.
  88. Wehner, D., C. Jahn and G. Weidinger, 2015 Use of the TetON System to Study Molecular Mechanisms of Zebrafish Regeneration. J Vis Exp: e52756.
  89. Wagner, K., M. Groger, O. McCook, A. Scheuerle, P. Asfar et al., 2015 Blunt Chest Trauma in Mice after Cigarette Smoke-Exposure: Effects of Mechanical Ventilation with 100 % O2. PLoS One 10: e0132810.
  90. Vogl, A. M., M. M. Brockmann, S. A. Giusti, G. Maccarrone, C. A. Vercelli et al., 2015 Neddylation inhibition impairs spine development, destabilizes synapses and deteriorates cognition. Nat Neurosci 18: 239-251.
  91. Vettorazzi, S., C. Bode, L. Dejager, L. Frappart, E. Shelest et al., 2015 Glucocorticoids limit acute lung inflammation in concert with inflammatory stimuli by induction of SphK1. Nat Commun 6: 7796.
  92. Theiss-Suennemann, J., K. Jorss, J. J. Messmann, S. D. Reichardt, E. Montes-Cobos et al., 2015 Glucocorticoids attenuate acute graft-versus-host disease by suppressing the cytotoxic capacity of CD8(+) T cells. J Pathol 235: 646-655.
  93. Sirko, S., M. Irmler, S. Gascon, S. Bek, S. Schneider et al., 2015 Astrocyte reactivity after brain injury-: The role of galectins 1 and 3. Glia 63: 2340-2361.
  94. Singh, K., P. Maity, L. Krug, P. Meyer, N. Treiber et al., 2015 Superoxide anion radicals induce IGF-1 resistance through concomitant activation of PTP1B and PTEN. EMBO Mol Med 7: 59-77.
  95. Schoen, M., J. M. Reichel, M. Demestre, S. Putz, D. Deshpande et al., 2015 Super-Resolution Microscopy Reveals Presynaptic Localization of the ALS/FTD Related Protein FUS in Hippocampal Neurons. Front Cell Neurosci 9: 496.
  96. Schatton, T., J. Yang, S. Kleffel, M. Uehara, S. R. Barthel et al., 2015 ABCB5 Identifies Immunoregulatory Dermal Cells. Cell Rep 12: 1564-1574.
  97. Messmann, J. J., T. Reisser, F. Leithauser, M. B. Lutz, K. M. Debatin et al., 2015 In vitro-generated MDSCs prevent murine GVHD by inducing type 2 T cells without disabling antitumor cytotoxicity. Blood 126: 1138-1148.
  98. Langgartner, D., A. M. Fuchsl, N. Uschold-Schmidt, D. A. Slattery and S. O. Reber, 2015 Chronic subordinate colony housing paradigm: a mouse model to characterize the consequences of insufficient glucocorticoid signaling. Front Psychiatry 6: 18.
  99. Kemmler, J., R. Bindl, O. McCook, F. Wagner, M. Groger et al., 2015 Exposure to 100% Oxygen Abolishes the Impairment of Fracture Healing after Thoracic Trauma. PLoS One 10: e0131194.
  100. Kalbitz, M., J. J. Grailer, F. Fattahi, L. Jajou, T. J. Herron et al., 2015 Role of extracellular histones in the cardiomyopathy of sepsis. FASEB J 29: 2185-2193.
  101. Jiang D, S.-K. K., 2015 Mesenchymal Stem Cells in Wound Repair, Tissue Homeostasis, and Aging, pp. 287-318 in Stem Cell Aging: Mechanisms, Consequences, Rejuvenation, edited by J. H. Geiger H, Florian MC, eds. Springer, Vienna.
  102. Hafner, S., K. Wagner, M. Wepler, J. Matallo, M. Groger et al., 2015 Physiological and immune-biological characterization of a long-term murine model of blunt chest trauma. Shock 43: 140-147.
  103. Denk, S., R. Wiegner, F. M. Hones, D. A. Messerer, P. Radermacher et al., 2015 Early Detection of Junctional Adhesion Molecule-1 (JAM-1) in the Circulation after Experimental and Clinical Polytrauma. Mediators Inflamm 2015: 463950.
  104. Asfar, P., M. Singer and P. Radermacher, 2015 Understanding the benefits and harms of oxygen therapy. Intensive Care Med 41: 1118-1121.
  105. Anastasiadou, S., S. Liebenehm, D. Sinske, C. Meyer zu Reckendorf, B. Moepps et al., 2015 Neuronal expression of the transcription factor serum response factor modulates myelination in a mouse multiple sclerosis model. Glia 63: 958-976.
  106. Zhou, W., M. Y. Fong, Y. Min, G. Somlo, L. Liu et al., 2014 Cancer-secreted miR-105 destroys vascular endothelial barriers to promote metastasis. Cancer Cell 25: 501-515.
  107. Witte, J., W. Kahler, T. Wunderlich, P. Radermacher, C. Wohlrab et al., 2014 Dose-time dependency of hyperbaric hyperoxia-induced DNA strand breaks in human immune cells visualized with the comet assay. Undersea Hyperb Med 41: 171-181.
  108. Wehner, D., W. Cizelsky, M. D. Vasudevaro, G. Ozhan, C. Haase et al., 2014 Wnt/beta-catenin signaling defines organizing centers that orchestrate growth and differentiation of the regenerating zebrafish caudal fin. Cell Rep 6: 467-481.
  109. Vogt, J. A., U. Wachter, K. Wagner, E. Calzia, M. Groger et al., 2014 Effects of glycemic control on glucose utilization and mitochondrial respiration during resuscitated murine septic shock. Intensive Care Med Exp 2: 19.
  110. Qi, Y., D. Jiang, A. Sindrilaru, A. Stegemann, S. Schatz et al., 2014 TSG-6 released from intradermally injected mesenchymal stem cells accelerates wound healing and reduces tissue fibrosis in murine full-thickness skin wounds. J Invest Dermatol 134: 526-537.
  111. McCook, O., P. Radermacher, C. Volani, P. Asfar, A. Ignatius et al., 2014 H2S during circulatory shock: Some unresolved questions. Nitric Oxide 41: 48-61.
  112. Lehnert, C., M. Weiswange, I. Jeremias, C. Bayer, M. Grunert et al., 2014 TRAIL-receptor costimulation inhibits proximal TCR signaling and suppresses human T cell activation and proliferation. J Immunol 193: 4021-4031.
  113. Kowal, J., M. Tkach and C. Thery, 2014 Biogenesis and secretion of exosomes. Curr Opin Cell Biol 29: 116-125.
  114. Haffner-Luntzer, M., A. Heilmann, A. Rapp, S. Beie, T. Schinke et al., 2014 Midkine Deficiency Delays Chondrogenesis during the Early Phase of Fracture Healing in Mice PLoS One 9: e116282.
  115. Geurtzen, K., F. Knopf, D. Wehner, L. F. Huitema, S. Schulte-Merker et al., 2014 Mature osteoblasts dedifferentiate in response to traumatic bone injury in the zebrafish fin and skull. Development 141: 2225-2234.
  116. Eisenbacher, J. L., H. Schrezenmeier, B. Jahrsdorfer, C. Kaltenmeier, M. T. Rojewski et al., 2014 S100A4 and uric acid promote mesenchymal stromal cell induction of IL-10+/IDO+ lymphocytes. J Immunol 192: 6102-6110.
  117. Stern, S., S. Haverkamp, D. Sinske, A. Tedeschi, U. Naumann et al., 2013 The transcription factor serum response factor stimulates axon regeneration through cytoplasmic localization and cofilin interaction. J Neurosci 33: 18836-18848.
  118. Sirko, S., G. Behrendt, P. A. Johansson, P. Tripathi, M. Costa et al., 2013 Reactive glia in the injured brain acquire stem cell properties in response to sonic hedgehog. [corrected]. Cell Stem Cell 12: 426-439.
  119. Sindrilaru, A., and K. Scharffetter-Kochanek, 2013 Disclosure of the Culprits: Macrophages-Versatile Regulators of Wound Healing. Adv Wound Care (New Rochelle) 2: 357-368.
  120. Seichter, F., A. Wilk, K. Worle, S. S. Kim, J. A. Vogt et al., 2013 Multivariate determination of 13CO2/12CO2 ratios in exhaled mouse breath with mid-infrared hollow waveguide gas sensors. Anal Bioanal Chem 405: 4945-4951.
  121. Saxena, S., F. Roselli, K. Singh, K. Leptien, J. P. Julien et al., 2013 Neuroprotection through excitability and mTOR required in ALS motoneurons to delay disease and extend survival. Neuron 80: 80-96.
  122. Maqbool, A., M. Lattke, T. Wirth and B. Baumann, 2013 Sustained, neuron-specific IKK/NF-kappaB activation generates a selective neuroinflammatory response promoting local neurodegeneration with aging. Mol Neurodegener 8: 40.
  123. Keuper, M., I. Wernstedt Asterholm, P. E. Scherer, M. A. Westhoff, P. Moller et al., 2013 TRAIL (TNF-related apoptosis-inducing ligand) regulates adipocyte metabolism by caspase-mediated cleavage of PPARgamma. Cell Death Dis 4: e474.
  124. Jiang, D., Y. Qi, N. G. Walker, A. Sindrilaru, A. Hainzl et al., 2013 The effect of adipose tissue derived MSCs delivered by a chemically defined carrier on full-thickness cutaneous wound healing. Biomaterials 34: 2501-2515.
  125. Hartmann, N., J. J. Messmann, F. Leithauser, M. Weiswange, M. Kluge et al., 2013 Recombinant CD95-Fc (APG101) prevents graft-versus-host disease in mice without disabling antitumor cytotoxicity and T-cell functions. Blood 121: 556-565.
  126. Grotek, B., D. Wehner and G. Weidinger, 2013 Notch signaling coordinates cellular proliferation with differentiation during zebrafish fin regeneration. Development 140: 1412-1423.
  127. Frohlich, S., J. Boylan and P. McLoughlin, 2013 Hypoxia-induced inflammation in the lung: a potential therapeutic target in acute lung injury? Am J Respir Cell Mol Biol 48: 271-279.
  128. Bardehle, S., M. Kruger, F. Buggenthin, J. Schwausch, J. Ninkovic et al., 2013 Live imaging of astrocyte responses to acute injury reveals selective juxtavascular proliferation. Nat Neurosci 16: 580-586.
  129. Tuder, R. M., and I. Petrache, 2012 Pathogenesis of chronic obstructive pulmonary disease. J Clin Invest 122: 2749-2755.
  130. Schmeisser, M. J., B. Baumann, S. Johannsen, G. F. Vindedal, V. Jensen et al., 2012 IkappaB kinase/nuclear factor kappaB-dependent insulin-like growth factor 2 (Igf2) expression regulates synapse formation and spine maturation via Igf2 receptor signaling. J Neurosci 32: 5688-5703.
  131. Matthay, M. A., L. B. Ware and G. A. Zimmerman, 2012 The acute respiratory distress syndrome. J Clin Invest 122: 2731-2740.
  132. Kleiman, A., S. Hubner, J. M. Rodriguez Parkitna, A. Neumann, S. Hofer et al., 2012 Glucocorticoid receptor dimerization is required for survival in septic shock via suppression of interleukin-1 in macrophages. FASEB J 26: 722-729.
  133. Ehrnthaller, C., U. Amara, S. Weckbach, M. Kalbitz, M. Huber-Lang et al., 2012 Alteration of complement hemolytic activity in different trauma and sepsis models. J Inflamm Res 5: 59-66.
  134. Dyson, A., F. Simon, A. Seifritz, O. Zimmerling, J. Matallo et al., 2012 Bladder tissue oxygen tension monitoring in pigs subjected to a range of cardiorespiratory and pharmacological challenges. Intensive Care Med 38: 1868-1876.
  135. Burk, A. M., M. Martin, M. A. Flierl, D. Rittirsch, M. Helm et al., 2012 Early complementopathy after multiple injuries in humans. Shock 37: 348-354.
  136. Sindrilaru, A., T. Peters, S. Wieschalka, C. Baican, A. Baican et al., 2011 An unrestrained proinflammatory M1 macrophage population induced by iron impairs wound healing in humans and mice. J Clin Invest 121: 985-997.
  137. Simon, C., M. Gotz and L. Dimou, 2011 Progenitors in the adult cerebral cortex: cell cycle properties and regulation by physiological stimuli and injury. Glia 59: 869-881.
  138. Shang, X., J. A. Cancelas, L. Li, F. Guo, W. Liu et al., 2011 R-Ras and Rac GTPase cross-talk regulates hematopoietic progenitor cell migration, homing, and mobilization. J Biol Chem 286: 24068-24078.
  139. Kohler, A., H. Geiger and M. Gunzer, 2011 Imaging hematopoietic stem cells in the marrow of long bones in vivo. Methods Mol Biol 750: 215-224.
  140. Knopf, F., C. Hammond, A. Chekuru, T. Kurth, S. Hans et al., 2011 Bone regenerates via dedifferentiation of osteoblasts in the zebrafish fin. Dev Cell 20: 713-724.
  141. Johnson, J. L., H. Hong, J. Monfregola and S. D. Catz, 2011 Increased survival and reduced neutrophil infiltration of the liver in Rab27a- but not Munc13-4-deficient mice in lipopolysaccharide-induced systemic inflammation. Infect Immun 79: 3607-3618.
  142. Hoth, J. J., J. D. Wells, E. M. Hiltbold, C. E. McCall and B. K. Yoza, 2011 Mechanism of neutrophil recruitment to the lung after pulmonary contusion. Shock 35: 604-609.
  143. Boda, E., F. Vigano, P. Rosa, M. Fumagalli, V. Labat-Gest et al., 2011 The GPR17 receptor in NG2 expressing cells: focus on in vivo cell maturation and participation in acute trauma and chronic damage. Glia 59: 1958-1973.
  144. Ryan, M. A., K. J. Nattamai, E. Xing, D. Schleimer, D. Daria et al., 2010 Pharmacological inhibition of EGFR signaling enhances G-CSF-induced hematopoietic stem cell mobilization. Nat Med 16: 1141-1146.
  145. Baumgart, K., F. Wagner, M. Groger, S. Weber, E. Barth et al., 2010 Cardiac and metabolic effects of hypothermia and inhaled hydrogen sulfide in anesthetized and ventilated mice. Crit Care Med 38: 588-595.
  146. Groger, M., S. Oter, V. Simkova, M. Bolten, A. Koch et al., 2009 DNA damage after long-term repetitive hyperbaric oxygen exposure. J Appl Physiol (1985) 106: 311-315.
  147. Chao, J., J. G. Wood and N. C. Gonzalez, 2009 Alveolar hypoxia, alveolar macrophages, and systemic inflammation. Respir Res 10: 54.
  148. Reber, S. O., L. Birkeneder, A. H. Veenema, F. Obermeier, W. Falk et al., 2007 Adrenal insufficiency and colonic inflammation after a novel chronic psycho-social stress paradigm in mice: implications and mechanisms. Endocrinology 148: 670-682.
  149. Xing, Z., M. A. Ryan, D. Daria, K. J. Nattamai, G. Van Zant et al., 2006 Increased hematopoietic stem cell mobilization in aged mice. Blood 108: 2190-2197.
  150. Perl, M., F. Gebhard, S. Braumuller, B. Tauchmann, U. B. Bruckner et al., 2006 The pulmonary and hepatic immune microenvironment and its contribution to the early systemic inflammation following blunt chest trauma. Crit Care Med 34: 1152-1159.
  151. Knoll, B., O. Kretz, C. Fiedler, S. Alberti, G. Schutz et al., 2006 Serum response factor controls neuronal circuit assembly in the hippocampus. Nat Neurosci 9: 195-204.
  152. Geiger, H., S. J. Szilvassy, P. Ragland and G. Van Zant, 2004 Genetic analysis of progenitor cell mobilization by granulocyte colony-stimulating factor: verification and mechanisms for loci on murine chromosomes 2 and 11. Exp Hematol 32: 60-67.
  153. Bernard, G. R., A. Artigas, K. L. Brigham, J. Carlet, K. Falke et al., 1994 The American-European Consensus Conference on ARDS. Definitions, mechanisms, relevant outcomes, and clinical trial coordination. Am J Respir Crit Care Med 149: 818-824.