SFB 1149

Ausgewählte Publikationen

  1. Hartmann, C., M. Groger, J.P. Noirhomme, A. Scheuerle, P. Moller, U. Wachter, M. Huber-Lang, B. Nussbaum, B. Jung, T. Merz, O. McCook, S. Kress, B. Stahl, E. Calzia, M. Georgieff, P. Radermacher, and M. Wepler. 2019. In-Depth Characterization of the Effects of Cigarette Smoke Exposure on the Acute Trauma Response and Hemorrhage in Mice. Shock. 51:68-77.
  2. Xu, P., J.U. Werner, S. Milerski, C.M. Hamp, T. Kuzenko, M. Jahnert, P. Gottmann, L. de Roy, D. Warnecke, A. Abaei, A. Palmer, M. Huber-Lang, L. Dürselen, V. Rasche, A. Schurmann, M. Wabitsch, and U. Knippschild. 2018. Diet-Induced Obesity Affects Muscle Regeneration After Murine Blunt Muscle Trauma-A Broad Spectrum Analysis. Frontiers in physiology. 9:674.
  3. Wiesner, D., L. Tar, B. Linkus, A. Chandrasekar, F. Olde Heuvel, L. Dupuis, W. Tsao, P.C. Wong, A. Ludolph, and F. Roselli. 2018. Reversible induction of TDP-43 granules in cortical neurons after traumatic injury. Exp Neurol. 299:15-25.
  4. Werner, J.U., K. Todter, P. Xu, L. Lockhart, M. Jahnert, P. Gottmann, A. Schurmann, L. Scheja, M. Wabitsch, and U. Knippschild. 2018. Comparison of Fatty Acid and Gene Profiles in Skeletal Muscle in Normal and Obese C57BL/6J Mice before and after Blunt Muscle Injury. Frontiers in physiology. 9:19.
  5. Wepler, M., T. Merz, U. Wachter, J. Vogt, E. Calzia, A. Scheuerle, P. Moller, M. Groger, S. Kress, M. Fink, B. Lukaschewski, G. Rumm, B. Stahl, M. Georgieff, M. Huber-Lang, R. Torregrossa, M. Whiteman, O. McCook, P. Radermacher, and C. Hartmann. 2018. The Mitochondria-Targeted H2S-donor AP39 in a Murine Model of Combined Hemorrhagic Shock and Blunt Chest Trauma. Shock.
  6. Wepler, M., J. Demiselle, P. Radermacher, P. Asfar, and E. Calzia. 2018. Before the ICU: does emergency room hyperoxia affect outcome? Crit Care. 22:59.
  7. Tu, J., S. Stoner, P.D. Fromm, T. Wang, D. Chen, J. Tuckermann, M.S. Cooper, M.J. Seibel, and H. Zhou. 2018. Endogenous glucocorticoid signaling in chondrocytes attenuates joint inflammation and damage. FASEB J. 32:478-487.
  8. Seichter, F., E. Tutuncu, L.T. Hagemann, J. Vogt, U. Wachter, M. Groger, S. Kress, P. Radermacher, and B. Mizaikoff. 2018. Online monitoring of carbon dioxide and oxygen in exhaled mouse breath via substrate-integrated hollow waveguide Fourier-transform infrared-luminescence spectroscopy. J Breath Res. 12:036018.
  9. Rapp, A.E., Y. Hachemi, J. Kemmler, M. Koenen, J. Tuckermann, and A. Ignatius. 2018. Induced global deletion of glucocorticoid receptor impairs fracture healing. FASEB J. 32:2235-2245.
  10. Prystaz, K., K. Kaiser, A. Kovtun, M. Haffner-Luntzer, V. Fischer, A.E. Rapp, A. Liedert, G. Strauss, G.H. Waetzig, S. Rose-John, and A. Ignatius. 2018. Distinct effects of interleukin-6 classic and trans-signaling in bone fracture healing. The American Journal of Pathology. 188:474-490.
  11. Picke, A.K., G.M. Campbell, M. Bluher, U. Krugel, F.N. Schmidt, E. Tsourdi, M. Winzer, M. Rauner, V. Vukicevic, B. Busse, J. Salbach-Hirsch, J.P. Tuckermann, J.C. Simon, U. Anderegg, L.C. Hofbauer, and A. Saalbach. 2018. Thy-1 (CD90) promotes bone formation and protects against obesity. Sci Transl Med. 10.
  12. Mettang, M., S.N. Reichel, M. Lattke, A. Palmer, A. Abaei, V. Rasche, M. Huber-Lang, B. Baumann, and T. Wirth. 2018. IKK2/NF-kappaB signaling protects neurons after traumatic brain injury. FASEB J. 32:1916-1932.
  13. Merz, T., M. Wepler, B. Nussbaum, J. Vogt, E. Calzia, R. Wang, C. Szabo, P. Radermacher, and O. McCook. 2018. Cystathionine-gamma-lyase expression is associated with mitochondrial respiration during sepsis-induced acute kidney injury in swine with atherosclerosis. Intensive Care Med Exp. 6:43.
  14. Merz, T., B. Lukaschewski, D. Wigger, A. Rupprecht, M. Wepler, M. Groger, C. Hartmann, M. Whiteman, C. Szabo, R. Wang, C. Waller, P. Radermacher, and O. McCook. 2018. Interaction of the hydrogen sulfide system with the oxytocin system in the injured mouse heart. Intensive Care Med Exp. 6:41.
  15. Martin, T., A. Moglich, I. Felix, C. Fortsch, A. Rittlinger, A. Palmer, S. Denk, J. Schneider, L. Notbohm, M. Vogel, H. Geiger, S. Paschke, M. Huber-Lang, and H. Barth. 2018. Rho-inhibiting C2IN-C3 fusion toxin inhibits chemotactic recruitment of human monocytes ex vivo and in mice in vivo. Arch Toxicol. 92:323-336.
  16. Lesur, O., E. Delile, P. Asfar, and P. Radermacher. 2018. Hemodynamic support in the early phase of septic shock: a review of challenges and unanswered questions. Ann Intensive Care. 8:102.
  17. Lee, S., P. Liu, R. Teinturier, J. Jakob, M. Tschaffon, A. Tasdogan, R. Wittig, S. Hoeller, D. Baumhoer, L. Frappart, S. Vettorazzi, P. Bertolino, C. Zhang, and J. Tuckermann. 2018. Deletion of Menin in craniofacial osteogenic cells in mice elicits development of mandibular ossifying fibroma. Oncogene. 37:616-626.
  18. Langgartner, D., U. Wachter, C. Hartmann, M. Groger, J. Vogt, T. Merz, O. McCook, M. Fink, S. Kress, M. Georgieff, J.F. Kunze, P.L. Radermacher, S.O. Reber, and M. Wepler. 2018. Effects of Psychosocial Stress on Subsequent Hemorrhagic Shock and Resuscitation in Male Mice. Shock.
  19. Kuan, S.L., S. Fischer, S. Hafner, T. Wang, T. Syrovets, W. Liu, Y. Tokura, D.Y.W. Ng, A. Riegger, C. Fortsch, D. Jager, T.F.E. Barth, T. Simmet, H. Barth, and T. Weil. 2018. Boosting Antitumor Drug Efficacy with Chemically Engineered Multidomain Proteins. Adv Sci (Weinh). 5:1701036.
  20. Koenen, M., S. Culemann, S. Vettorazzi, G. Caratti, L. Frappart, W. Baum, G. Kronke, U. Baschant, and J.P. Tuckermann. 2018. Glucocorticoid receptor in stromal cells is essential for glucocorticoid-mediated suppression of inflammation in arthritis. Ann Rheum Dis. 77:1610-1618.
  21. Ignatius, A., and J. Tuckermann. 2018. New horizons for osteoanabolic treatment? Nat Rev Endocrinol. 14:508-509.
  22. Huber-Lang, M., J.D. Lambris, and P.A. Ward. 2018. Innate immune responses to trauma. Nat Immunol. 19:327-341.
  23. Huber-Lang, M., K.N. Ekdahl, R. Wiegner, K. Fromell, and B. Nilsson. 2018. Auxiliary activation of the complement system and its importance for the pathophysiology of clinical conditions. Semin Immunopathol. 40:87-102.
  24. Hildebrandt, S., U. Baschant, S. Thiele, J. Tuckermann, L.C. Hofbauer, and M. Rauner. 2018. Glucocorticoids suppress Wnt16 expression in osteoblasts in vitro and in vivo. Sci Rep. 8:8711.
  25. Haffner-Luntzer, M., A. Kovtun, I. Lackner, Y. Modinger, S. Hacker, A. Liedert, J. Tuckermann, and A. Ignatius. 2018. Estrogen receptor alpha- (ERalpha), but not ERbeta-signaling, is crucially involved in mechanostimulation of bone fracture healing by whole-body vibration. Bone. 110:11-20.
  26. Hachemi, Y., A.E. Rapp, A.K. Picke, G. Weidinger, A. Ignatius, and J. Tuckermann. 2018. Molecular mechanisms of glucocorticoids on skeleton and bone regeneration after fracture. J Mol Endocrinol. 61:R75-R90.
  27. Groger, M., M. Wepler, U. Wachter, T. Merz, O. McCook, S. Kress, B. Lukaschewski, S. Hafner, M. Huber-Lang, E. Calzia, M. Georgieff, N. Nagahara, C. Szabo, P. Radermacher, and C. Hartmann. 2018. The Effects of Genetic 3-Mercaptopyruvate Sulfurtransferase Deficiency in Murine Traumatic-Hemorrhagic Shock. Shock.
  28. Gačanin, J., J. Hedrich, S. Sieste, G. Glasser, I. Lieberwirth, C. Schilling, S. Fischer, H. Barth, B. Knöll, C.V. Synatschke, and T. Weil. 2018. Autonomous Ultrafast Self-Healing Hydrogels by pH-Responsive Functional Nanofiber Gelators as Cell Matrices. Adv Mater. In Press:e1805044.
  29. Denk, S., S. Weckbach, P. Eisele, C.K. Braun, R. Wiegner, J.J. Ohmann, L. Wrba, F.M. Hoenes, P. Kellermann, P. Radermacher, U. Wachter, S. Hafner, O. McCook, A. Schultze, A. Palmer, S. Braumuller, F. Gebhard, and M. Huber-Lang. 2018. Role of Hemorrhagic Shock in Experimental Polytrauma. Shock. 49:154-163.
  30. Demiselle, J., M. Wepler, C. Hartmann, P. Radermacher, F. Schortgen, F. Meziani, M. Singer, V. Seegers, P. Asfar, and H.S. investigators. 2018. Hyperoxia toxicity in septic shock patients according to the Sepsis-3 criteria: a post hoc analysis of the HYPER2S trial. Ann Intensive Care. 8:90.
  31. Datzmann, T., M. Wepler, U. Wachter, J.A. Vogt, O. McCook, T. Merz, E. Calzia, M. Groger, C. Hartmann, P. Asfar, P. Radermacher, and N.B. Lukas. 2018. Cardiac Effects of Hyperoxia During Resuscitation from Hemorrhagic Shock in Swine. Shock.
  32. Böbel, T.S., S.B. Hackl, D. Langgartner, M.N. Jarczok, N. Rohleder, G.A. Rook, C.A. Lowry, H. Gundel, C. Waller, and S.O. Reber. 2018. Less immune activation following social stress in rural vs. urban participants raised with regular or no animal contact, respectively. Proc Natl Acad Sci U S A. 115:5259-5264.
  33. Amann, E.M., M.T. Rojewski, S. Rodi, D. Fürst, J. Fiedler, A. Palmer, S. Braumüller, M. Huber-Lang, H. Schrezenmeier, and R.E. Brenner. 2018. Systemic recovery and therapeutic effects of transplanted allogenic and xenogenic mesenchymal stromal cells in a rat blunt chest trauma model. In Cytotherapy. Vol. 20. 218-231.
  34. Ahmad, M., T. Kroll, J. Jakob, A. Rauch, A. Ploubidou, and J. Tuckermann. 2018. Cell-based RNAi screening and high-content analysis in primary calvarian osteoblasts applied to identification of osteoblast differentiation regulators. Sci Rep. 8:14045.
  35. Zimprich, A., G. Mroz, C. Meyer Zu Reckendorf, S. Anastasiadou, P. Forstner, L. Garrett, S.M. Holter, L. Becker, J. Rozman, C. Prehn, B. Rathkolb, K. Moreth, W. Wurst, T. Klopstock, M. Klingenspor, J. Adamski, E. Wolf, R. Bekeredjian, H. Fuchs, V. Gailus-Durner, M.H. de Angelis, and B. Knöll. 2017. Serum Response Factor (SRF) Ablation Interferes with Acute Stress-Associated Immediate and Long-Term Coping Mechanisms. Mol Neurobiol. 54:8242-8262.
  36. Wrba, L., A. Palmer, C.K. Braun, and M. Huber-Lang. 2017. Evaluation of gut-blood barrier dysfunction in various models of trauma, hemorrhagic shock, and burn injury. J Trauma Acute Care Surg. 83:944-953.
  37. Wehner, D., T.M. Tsarouchas, A. Michael, C. Haase, G. Weidinger, M.M. Reimer, T. Becker, and C.G. Becker. 2017. Wnt signaling controls pro-regenerative Collagen XII in functional spinal cord regeneration in zebrafish. Nat Commun. 8:126.
  38. Wanner, R., M. Gey, A. Abaei, D. Warnecke, L. de Roy, L. Dürselen, V. Rasche, and B. Knöll. 2017. Functional and Molecular Characterization of a Novel Traumatic Peripheral Nerve-Muscle Injury Model. Neuromolecular Med. 19:357-374.
  39. Sportelli, M.C., E. Tutuncu, R.A. Picca, M. Valentini, A. Valentini, C. Kranz, B. Mizaikoff, H. Barth, and N. Cioffi. 2017. Inhibiting P. fluorescens biofilms with fluoropolymer-embedded silver nanoparticles: an in-situ spectroscopic study. Sci Rep. 7:11870.
  40. Singh, K., L. Krug, A. Basu, P. Meyer, N. Treiber, S. Vander Beken, M. Wlaschek, S. Kochanek, W. Bloch, H. Geiger, P. Maity, and K. Scharffetter-Kochanek. 2017. Alpha-Ketoglutarate Curbs Differentiation and Induces Cell Death in Mesenchymal Stromal Precursors with Mitochondrial Dysfunction. Stem Cells. 35:1704-1718.
  41. Singh, K., L. Krug, A. Basu, P. Meyer, N. Treiber, S. Vander Beken, M. Wlaschek, S. Kochanek, W. Bloch, H. Geiger, P. Maity, and K. Scharffetter-Kochanek. 2017. Alpha-Ketoglutarate Curbs Differentiation and Induces Cell Death in Mesenchymal Stromal Precursors with Mitochondrial Dysfunction. Stem Cells. 35:1704-1718.
  42. Singh, K., L. Krug, A. Basu, P. Meyer, N. Treiber, S. Vander Beken, M. Wlaschek, S. Kochanek, W. Bloch, H. Geiger, P. Maity, and K. Scharffetter-Kochanek. 2017. Alpha-Ketoglutarate Curbs Differentiation and Induces Cell Death in Mesenchymal Stromal Precursors with Mitochondrial Dysfunction. Stem Cells. 35:1704-1718.
  43. Singh, K., L. Krug, A. Basu, P. Meyer, N. Treiber, S. Vander Beken, M. Wlaschek, S. Kochanek, W. Bloch, H. Geiger, P. Maity, and K. Scharffetter-Kochanek. 2017. Alpha-Ketoglutarate Curbs Differentiation and Induces Cell Death in Mesenchymal Stromal Precursors with Mitochondrial Dysfunction. Stem Cells. 35:1704-1718.
  44. Seichter, F., J. Vogt, P. Radermacher, and B. Mizaikoff. 2017. Nonlinear calibration transfer based on hierarchical Bayesian models and Lagrange Multipliers: Error bounds of estimates via Monte Carlo - Markov Chain sampling. Anal Chim Acta. 951:32-45.
  45. Seichter, F., J. Vogt, P. Radermacher, and B. Mizaikoff. 2017. Response-surface fits and calibration transfer for the correction of the oxygen effect in the quantification of carbon dioxide via FTIR spectroscopy. Anal Chim Acta. 972:16-27.
  46. Schimunek, L., R. Serve, M.P.J. Teuben, P. Stormann, B. Auner, M. Woschek, R. Pfeifer, K. Horst, T.P. Simon, M. Kalbitz, R. Sturm, H.C. Pape, F. Hildebrand, I. Marzi, and B. Relja. 2017. Early decreased TLR2 expression on monocytes is associated with their reduced phagocytic activity and impaired maturation in a porcine polytrauma model. PloS one. 12:e0187404.
  47. Radermacher, P., S.M. Maggiore, and A. Mercat. 2017. Fifty Years of Research in ARDS. Gas Exchange in Acute Respiratory Distress Syndrome. Am J Respir Crit Care Med. 196:964-984.
  48. Pfaender, S., A.K. Sauer, S. Hagmeyer, K. Mangus, L. Linta, S. Liebau, J. Bockmann, G. Huguet, T. Bourgeron, T.M. Boeckers, and A.M. Grabrucker. 2017. Zinc deficiency and low enterocyte zinc transporter expression in human patients with autism related mutations in SHANK3. Sci Rep. 7:45190.
  49. Owlarn, S., F. Klenner, D. Schmidt, F. Rabert, A. Tomasso, H. Reuter, M.A. Mulaw, S. Moritz, L. Gentile, G. Weidinger, and K. Bartscherer. 2017. Generic wound signals initiate regeneration in missing-tissue contexts. Nat Commun. 8:2282.
  50. Nussbaum, B.L., T. Stenzel, T. Merz, A. Scheuerle, O. McCook, U. Wachter, J.A. Vogt, J. Matallo, H. Gassler, M. Groger, M. Matejovic, E. Calzia, L. Lampl, M. Georgieff, P. Moller, P. Asfar, P. Radermacher, and S. Hafner. 2017. Hyperoxia or Therapeutic Hypothermia During Resuscitation from Non-Lethal Hemorrhagic Shock in Swine. Shock. 48:564-570.
  51. Ng, D.Y.W., R. Vill, Y. Wu, K. Koynov, Y. Tokura, W. Liu, S. Sihler, A. Kreyes, S. Ritz, H. Barth, U. Ziener, and T. Weil. 2017. Directing intracellular supramolecular assembly with N-heteroaromatic quaterthiophene analogues. Nat Commun. 8:1850.
  52. Mueller, K.M., K. Hartmann, D. Kaltenecker, S. Vettorazzi, M. Bauer, L. Mauser, S. Amann, S. Jall, K. Fischer, H. Esterbauer, T.D. Muller, M.H. Tschop, C. Magnes, J. Haybaeck, T. Scherer, N. Bordag, J.P. Tuckermann, and R. Moriggl. 2017. Adipocyte Glucocorticoid Receptor Deficiency Attenuates Aging- and HFD-Induced Obesity and Impairs the Feeding-Fasting Transition. Diabetes. 66:272-286.
  53. Merz, T., J.A. Vogt, U. Wachter, E. Calzia, C. Szabo, R. Wang, P. Radermacher, and O. McCook. 2017. Impact of hyperglycemia on cystathionine-gamma-lyase expression during resuscitated murine septic shock. Intensive Care Med Exp. 5:30.
  54. Merz, T., T. Stenzel, B. Nussbaum, M. Wepler, C. Szabo, R. Wang, P. Radermacher, and O. McCook. 2017. Cardiovascular disease and resuscitated septic shock lead to the downregulation of the H2S-producing enzyme cystathionine-gamma-lyase in the porcine coronary artery. Intensive Care Med Exp. 5:17.
  55. Magadum, A., Y. Ding, L. He, T. Kim, M.D. Vasudevarao, Q. Long, K. Yang, N. Wickramasinghe, H.V. Renikunta, N. Dubois, G. Weidinger, Q. Yang, and F.B. Engel. 2017. Live cell screening platform identifies PPARdelta as a regulator of cardiomyocyte proliferation and cardiac repair. Cell Res. 27:1002-1019.
  56. Losing, P., C.E. Niturad, M. Harrer, C.M.Z. Reckendorf, T. Schatz, D. Sinske, H. Lerche, S. Maljevic, and B. Knöll. 2017. SRF modulates seizure occurrence, activity induced gene transcription and hippocampal circuit reorganization in the mouse pilocarpine epilepsy model. Mol Brain. 10:30.
  57. Liu, P., S. Lee, J. Knöll, A. Rauch, S. Ostermay, J. Luther, N. Malkusch, U.H. Lerner, M.M. Zaiss, M. Neven, R. Wittig, M. Rauner, J.P. David, P. Bertolino, C.X. Zhang, and J.P. Tuckermann. 2017. Loss of menin in osteoblast lineage affects osteocyte-osteoclast crosstalk causing osteoporosis. Cell Death Differ. 24:672-682.
  58. Lattke, M., S.N. Reichel, A. Magnutzki, A. Abaei, V. Rasche, P. Walther, D.P. Calado, B. Ferger, T. Wirth, and B. Baumann. 2017. Transient IKK2 activation in astrocytes initiates selective non-cell-autonomous neurodegeneration. Mol Neurodegener. 12:16.
  59. Langgartner, D., D. Peterlik, S. Foertsch, A.M. Fuchsl, P. Brokmann, P.J. Flor, Z. Shen, J.G. Fox, N. Uschold-Schmidt, C.A. Lowry, and S.O. Reber. 2017. Individual differences in stress vulnerability: The role of gut pathobionts in stress-induced colitis. Brain Behav Immun. 64:23-32.
  60. Kroner, J., A. Kovtun, J. Kemmler, J.J. Messmann, G. Strauss, S. Seitz, T. Schinke, M. Amling, J. Kotrba, J. Dudeck, A. Dudeck, and A. Ignatius. 2017. Mast cells are critical regulators of bone fracture-induced inflammation and osteoclast formation and activity. J Bone Miner Res. 32:2431–2444.
  61. Kreidler, A.M., R. Benz, and H. Barth. 2017. Chloroquine derivatives block the translocation pores and inhibit cellular entry of Clostridium botulinum C2 toxin and Bacillus anthracis lethal toxin. Arch Toxicol. 91:1431-1445.
  62. Kovtun, A., S. Bergdolt, Y. Hagele, R. Matthes, J.D. Lambris, M. Huber-Lang, and A. Ignatius. 2017. Complement receptors C5aR1 and C5aR2 act differentially during the early immune response after bone fracture but are similarly involved in bone repair. Sci Rep. 7:14061.
  63. Kalbitz, M., C. Waller, M. Huber-Lang, F. Gebhard, C. Thiemermann, and P. Radermacher. 2017. Oxygen in the Heart: How Much is too Much? Shock. 47:531-532.
  64. Kalbitz, M., S. Schwarz, B. Weber, B. Bosch, J. Pressmar, F.M. Hoenes, C.K. Braun, K. Horst, T.P. Simon, R. Pfeifer, P. Stormann, H. Hummler, F. Gebhard, H.C. Pape, M. Huber-Lang, F. Hildebrand, and T.R. Group. 2017. Cardiac Depression in Pigs after Multiple Trauma - Characterization of Posttraumatic Structural and Functional Alterations. Sci Rep. 7:17861.
  65. Kalbitz, M., J. Pressmar, J. Stecher, B. Weber, M. Weiss, S. Schwarz, E. Miltner, F. Gebhard, and M. Huber-Lang. 2017. The Role of Troponin in Blunt Cardiac Injury After Multiple Trauma in Humans. World J Surg. 41:162-169.
  66. Kalbitz, M., E.M. Amann, B. Bosch, A. Palmer, A. Schultze, J. Pressmar, B. Weber, M. Wepler, F. Gebhard, H. Schrezenmeier, R. Brenner, and M. Huber-Lang. 2017. Experimental blunt chest trauma-induced myocardial inflammation and alteration of gap-junction protein connexin 43. PloS one. 12:e0187270.
  67. Itkin, T., A. Kumari, E. Schneider, S. Gur-Cohen, C. Ludwig, R. Brooks, O. Kollet, K. Golan, E. Khatib-Massalha, C.M. Russo, J.D. Chisholm, A. Rouhi, H. Geiger, E. Hornstein, W.G. Kerr, F. Kuchenbauer, and T. Lapidot. 2017. MicroRNA-155 promotes G-CSF-induced mobilization of murine hematopoietic stem and progenitor cells via propagation of CXCL12 signaling. Leukemia. 31:1247-1250.
  68. Husecken, Y., S. Muche, M. Kustermann, M. Klingspor, A. Palmer, S. Braumuller, M. Huber-Lang, K.M. Debatin, and G. Strauss. 2017. MDSCs are induced after experimental blunt chest trauma and subsequently alter antigen-specific T cell responses. Sci Rep. 7:12808.
  69. Hartmann, C., P. Radermacher, M. Wepler, and B. Nussbaum. 2017. Non-Hemodynamic Effects of Catecholamines. Shock. 48:390-400.
  70. Hartmann, C., B. Nussbaum, E. Calzia, P. Radermacher, and M. Wepler. 2017. Gaseous Mediators and Mitochondrial Function: The Future of Pharmacologically Induced Suspended Animation? Frontiers in physiology. 8:691.
  71. Hartmann, C., M. Loconte, E. Antonucci, M. Holzhauser, T. Holle, D. Katzsch, T. Merz, O. McCook, U. Wachter, J.A. Vogt, A. Hoffmann, M. Wepler, M. Groger, M. Matejovic, E. Calzia, M. Georgieff, P. Asfar, P. Radermacher, and B.L. Nussbaum. 2017. Effects of Hyperoxia During Resuscitation From Hemorrhagic Shock in Swine With Preexisting Coronary Artery Disease. Crit Care Med. 45:e1270-e1279.
  72. Hartmann, C., S. Hafner, A. Scheuerle, P. Moller, M. Huber-Lang, B. Jung, B. Nubaum, O. McCook, M. Groger, F. Wagner, S. Weber, B. Stahl, E. Calzia, M. Georgieff, C. Szabo, R. Wang, P. Radermacher, and K. Wagner. 2017. The Role of Cystathionine-gamma-Lyase In Blunt Chest Trauma in Cigarette Smoke Exposed Mice. Shock. 47:491-499.
  73. Halbgebauer, R., C.K. Braun, S. Denk, B. Mayer, P. Cinelli, P. Radermacher, G.A. Wanner, H.P. Simmen, F. Gebhard, D. Rittirsch, and M. Huber-Lang. 2017. Hemorrhagic shock drives glycocalyx, barrier and organ dysfunction early after polytrauma. J Crit Care. 44:229-237.
  74. Hagemeyer, N., K.M. Hanft, M.A. Akriditou, N. Unger, E.S. Park, E.R. Stanley, O. Staszewski, L. Dimou, and M. Prinz. 2017. Microglia contribute to normal myelinogenesis and to oligodendrocyte progenitor maintenance during adulthood. Acta Neuropathol. 134:441-458.
  75. Hafner, S., K. Wagner, S. Weber, M. Groger, M. Wepler, O. McCook, A. Scheuerle, B. Stahl, M. Huber-Lang, B. Jung, E. Calzia, M. Georgieff, P. Moller, M. Frick, P. Radermacher, and F. Wagner. 2017. Role of the Purinergic Receptor P2XR4 After Blunt Chest Trauma in Cigarette Smoke-Exposed Mice. Shock. 47:193-199.
  76. Haffner-Luntzer, M., F. Muller-Graf, R. Matthys, Y. Hägele, V. Fischer, R. Jonas, A. Abaei, F. Gebhard, V. Rasche, and A. Ignatius. 2017. Evaluation of high-resolution In Vivo MRI for longitudinal analysis of endochondral fracture healing in mice. PloS one. 12:e0174283.
  77. Haffner-Luntzer, M., F. Muller-Graf, R. Matthys, A. Abaei, R. Jonas, F. Gebhard, V. Rasche, and A. Ignatius. 2017. In Vivo Evaluation of Fracture Callus Development During Bone Healing in Mice Using an MRI-compatible Osteosynthesis Device for the Mouse Femur. J Vis Exp:e56679.
  78. Haffner-Luntzer, M., V. Fischer, K. Prystaz, A. Liedert, and A. Ignatius. 2017. The inflammatory phase of fracture healing is influenced by oestrogen status in mice. European Journal of Medical Research. 33:23.
  79. Guidi, N., M. Sacma, L. Standker, K. Soller, G. Marka, K. Eiwen, J.M. Weiss, F. Kirchhoff, T. Weil, J.A. Cancelas, M.C. Florian, and H. Geiger. 2017. Osteopontin attenuates aging-associated phenotypes of hematopoietic stem cells. EMBO J. 36:1463.
  80. Galuppo, P., S. Vettorazzi, J. Hovelmann, C.J. Scholz, J.P. Tuckermann, J. Bauersachs, and D. Fraccarollo. 2017. The glucocorticoid receptor in monocyte-derived macrophages is critical for cardiac infarct repair and remodeling. FASEB J. 31:5122-5132.
  81. Gačanin, J., A. Kovtun, S. Fischer, V. Schwager, J. Quambusch, S.L. Kuan, W. Liu, F. Boldt, C. Li, Z. Yang, D. Liu, Y. Wu, T. Weil, H. Barth, and A. Ignatius. 2017. Spatiotemporally Controlled Release of Rho-Inhibiting C3 Toxin from a Protein–DNA Hybrid Hydrogel for Targeted Inhibition of Osteoclast Formation and Activity. Adv Healthc Mater. 6:1700392.
  82. Foertsch, S., M. Haffner-Luntzer, J. Kroner, F. Gross, K. Kaiser, M. Erber, S.O. Reber, and A. Ignatius. 2017. Chronic psychosocial stress disturbs long-bone growth in adolescent mice. Dis Model Mech. 10:1399-1409.
  83. Foertsch, S., A.M. Fuchsl, S.D. Faller, H. Holzer, D. Langgartner, J. Messmann, G. Strauss, and S.O. Reber. 2017. Splenic glucocorticoid resistance following psychosocial stress requires physical injury. Sci Rep. 7:15730.
  84. Fattahi, F., M. Kalbitz, E.A. Malan, E. Abe, L. Jajou, M.S. Huber-Lang, M. Bosmann, M.W. Russell, F.S. Zetoune, and P.A. Ward. 2017. Complement-induced activation of MAPKs and Akt during sepsis: role in cardiac dysfunction. FASEB J. 31:4129-4139.
  85. Ernst, K., J. Schmid, M. Beck, M. Hagele, M. Hohwieler, P. Hauff, A.K. Uckert, A. Anastasia, M. Fauler, T. Jank, K. Aktories, M.R. Popoff, C. Schiene-Fischer, A. Kleger, M. Muller, M. Frick, and H. Barth. 2017. Hsp70 facilitates trans-membrane transport of bacterial ADP-ribosylating toxins into the cytosol of mammalian cells. Sci Rep. 7:2724.
  86. Denk, S., R.P. Taylor, R. Wiegner, E.M. Cook, M.A. Lindorfer, K. Pfeiffer, S. Paschke, T. Eiseler, M. Weiss, E. Barth, J.D. Lambris, M. Kalbitz, T. Martin, H. Barth, D.A.C. Messerer, F. Gebhard, and M.S. Huber-Lang. 2017. Complement C5a-Induced Changes in Neutrophil Morphology During Inflammation. Scand J Immunol. 86:143-155.
  87. Denk, S., M.D. Neher, D.A.C. Messerer, R. Wiegner, B. Nilsson, D. Rittirsch, K. Nilsson-Ekdahl, S. Weckbach, A. Ignatius, M. Kalbitz, F. Gebhard, M.E. Weiss, J. Vogt, P. Radermacher, J. Kohl, J.D. Lambris, and M.S. Huber-Lang. 2017. Complement C5a Functions as a Master Switch for the pH Balance in Neutrophils Exerting Fundamental Immunometabolic Effects. J Immunol. 198:4846-4854.
  88. Chandrasekar, A., F.O. Heuvel, A. Palmer, B. Linkus, A.C. Ludolph, T.M. Boeckers, B. Relja, M. Huber-Lang, and F. Roselli. 2017. Acute ethanol administration results in a protective cytokine and neuroinflammatory profile in traumatic brain injury. Int Immunopharmacol. 51:66-75.
  89. Braun, C.K., M. Kalbitz, R. Halbgebauer, P. Eisele, D.A.C. Messerer, S. Weckbach, A. Schultze, S. Braumuller, F. Gebhard, and M.S. Huber-Lang. 2017. Early structural changes of the heart after experimental polytrauma and hemorrhagic shock. PloS one. 12:e0187327.
  90. Bonfanti, E., P. Gelosa, M. Fumagalli, L. Dimou, F. Vigano, E. Tremoli, M. Cimino, L. Sironi, and M.P. Abbracchio. 2017. The role of oligodendrocyte precursor cells expressing the GPR17 receptor in brain remodeling after stroke. Cell Death Dis. 8:e2871.
  91. Bergdolt, S., A. Kovtun, Y. Hagele, A. Liedert, T. Schinke, M. Amling, M. Huber-Lang, and A. Ignatius. 2017. Osteoblast-specific overexpression of complement receptor C5aR1 impairs fracture healing. PloS one. 12:e0179512.
  92. Asfar, P., F. Schortgen, J. Boisrame-Helms, J. Charpentier, E. Guerot, B. Megarbane, D. Grimaldi, F. Grelon, N. Anguel, S. Lasocki, M. Henry-Lagarrigue, F. Gonzalez, F. Legay, C. Guitton, M. Schenck, J.M. Doise, J. Devaquet, T. Van Der Linden, D. Chatellier, J.P. Rigaud, J. Dellamonica, F. Tamion, F. Meziani, A. Mercat, D. Dreyfuss, V. Seegers, P. Radermacher, H.S. Investigators, and R.r. network. 2017. Hyperoxia and hypertonic saline in patients with septic shock (HYPERS2S): a two-by-two factorial, multicentre, randomised, clinical trial. Lancet Respir Med. 5:180-190.
  93. Wu, C.C., F. Kruse, M.D. Vasudevarao, J.P. Junker, D.C. Zebrowski, K. Fischer, E.S. Noel, D. Grun, E. Berezikov, F.B. Engel, A. van Oudenaarden, G. Weidinger, and J. Bakkers. 2016. Spatially Resolved Genome-wide Transcriptional Profiling Identifies BMP Signaling as Essential Regulator of Zebrafish Cardiomyocyte Regeneration. Dev Cell. 36:36-49.
  94. Winkelmann VE, G.F., Hobi N, Dietl P, Frick M. 2016. Establishment of a co-culture to mimic the alveolar-capillary barrier in vitro. Vol. 216. Acta Physiologica. S707.
  95. Wang, T., A. Riegger, M. Lamla, S. Wiese, P. Oeckl, M. Otto, Y. Wu, S. Fischer, H. Barth, S.L. Kuan, and T. Weil. 2016. Water-soluble allyl sulfones for dual site-specific labelling of proteins and cyclic peptides. Chemical Science. 7:3234-3239.
  96. Vigano, F., S. Schneider, M. Cimino, E. Bonfanti, P. Gelosa, L. Sironi, M.P. Abbracchio, and L. Dimou. 2016. GPR17 expressing NG2-Glia: Oligodendrocyte progenitors serving as a reserve pool after injury. Glia. 64:287-299.
  97. Stenzel, T., C. Weidgang, K. Wagner, F. Wagner, M. Groger, S. Weber, B. Stahl, U. Wachter, J. Vogt, E. Calzia, S. Denk, M. Georgieff, M. Huber-Lang, P. Radermacher, and O. McCook. 2016. Association of Kidney Tissue Barrier Disrupture and Renal Dysfunction in Resuscitated Murine Septic Shock. Shock. 46:398-404.
  98. Sroka, R., J. Van Lint, S.F. Katz, M.R. Schneider, A. Kleger, S. Paschke, T. Seufferlein, and T. Eiseler. 2016. Cortactin is a scaffolding platform for the E-cadherin adhesion complex and is regulated by protein kinase D1 phosphorylation. J Cell Sci. 129:2416-2429.
  99. Sehring, I.M., C. Jahn, and G. Weidinger. 2016. Zebrafish fin and heart: what's special about regeneration? Curr Opin Genet Dev. 40:48-56.
  100. Schoen, M., J.M. Reichel, M. Demestre, S. Putz, D. Deshpande, C. Proepper, S. Liebau, M.J. Schmeisser, A.C. Ludolph, J. Michaelis, and T.M. Boeckers. 2016. Super-Resolution Microscopy Reveals Presynaptic Localization of the ALS/FTD Related Protein FUS in Hippocampal Neurons. Front Cell Neurosci. 9:496.
  101. Schneider, S., A. Gruart, S. Grade, Y. Zhang, S. Kroger, F. Kirchhoff, G. Eichele, J.M. Delgado Garcia, and L. Dimou. 2016. Decrease in newly generated oligodendrocytes leads to motor dysfunctions and changed myelin structures that can be rescued by transplanted cells. Glia. 64:2201-2218.
  102. Schmidt, D., D. Peterlik, S.O. Reber, A. Lechner, and D.N. Mannel. 2016. Induction of Suppressor Cells and Increased Tumor Growth following Chronic Psychosocial Stress in Male Mice. PloS one. 11:e0159059.
  103. Reber, S.O., P.H. Siebler, N.C. Donner, J.T. Morton, D.G. Smith, J.M. Kopelman, K.R. Lowe, K.J. Wheeler, J.H. Fox, J.E. Hassell, Jr., B.N. Greenwood, C. Jansch, A. Lechner, D. Schmidt, N. Uschold-Schmidt, A.M. Fuchsl, D. Langgartner, F.R. Walker, M.W. Hale, G. Lopez Perez, W. Van Treuren, A. Gonzalez, A.L. Halweg-Edwards, M. Fleshner, C.L. Raison, G.A. Rook, S.D. Peddada, R. Knight, and C.A. Lowry. 2016. Immunization with a heat-killed preparation of the environmental bacterium Mycobacterium vaccae promotes stress resilience in mice. Proc Natl Acad Sci U S A. 113:E3130-3139.
  104. Rapp, A.E., R. Bindl, S. Recknagel, A. Erbacher, I. Muller, H. Schrezenmeier, C. Ehrnthaller, F. Gebhard, and A. Ignatius. 2016. Fracture Healing Is Delayed in Immunodeficient NOD/scidIL2Rgammacnull Mice. PloS one. 11:e0147465.
  105. Peter, S., M.M. Ten Brinke, J. Stedehouder, C.M. Reinelt, B. Wu, H. Zhou, K. Zhou, H.J. Boele, S.A. Kushner, M.G. Lee, M.J. Schmeisser, T.M. Boeckers, M. Schonewille, F.E. Hoebeek, and C.I. De Zeeuw. 2016. Dysfunctional cerebellar Purkinje cells contribute to autism-like behaviour in Shank2-deficient mice. Nat Commun. 7:12627.
  106. Masselink, W., N.J. Cole, F. Fenyes, S. Berger, C. Sonntag, A. Wood, P.D. Nguyen, N. Cohen, F. Knopf, G. Weidinger, T.E. Hall, and P.D. Currie. 2016. A somitic contribution to the apical ectodermal ridge is essential for fin formation. Nature. 535:542-546.
  107. Liu, P., M. Baumgart, M. Groth, J. Wittmann, H.M. Jack, M. Platzer, J.P. Tuckermann, and U. Baschant. 2016. Dicer ablation in osteoblasts by Runx2 driven cre-loxP recombination affects bone integrity, but not glucocorticoid-induced suppression of bone formation. Sci Rep. 6:32112.
  108. Li, Y., L. Chang, Y. Song, X. Gao, F. Roselli, J. Liu, W. Zhou, Y. Fang, W. Ling, H. Li, O.F. Almeida, and Y. Wu. 2016. Astrocytic GluN2A and GluN2B Oppose the Synaptotoxic Effects of Amyloid-beta1-40 in Hippocampal Cells. J Alzheimers Dis. 54:135-148.
  109. Kuan, S.L., C. Fortsch, D.Y. Ng, S. Fischer, Y. Tokura, W. Liu, Y. Wu, K. Koynov, H. Barth, and T. Weil. 2016. A Supramolecular Approach toward Bioinspired PAMAM-Dendronized Fusion Toxins. Macromol Biosci. 16:803-810.
  110. Kovtun, A., S. Bergdolt, R. Wiegner, P. Radermacher, M. Huber-Lang, and A. Ignatius. 2016. The crucial role of neutrophil granulocytes in bone fracture healing. Eur Cell Mater. 32:152-162.
  111. Knoller, E., T. Stenzel, F. Broeskamp, R. Hornung, A. Scheuerle, O. McCook, U. Wachter, J.A. Vogt, J. Matallo, M. Wepler, H. Gassler, M. Groger, M. Matejovic, E. Calzia, L. Lampl, M. Georgieff, P. Moller, P. Asfar, P. Radermacher, and S. Hafner. 2016. Effects of Hyperoxia and Mild Therapeutic Hypothermia During Resuscitation From Porcine Hemorrhagic Shock. Crit Care Med. 44:e264-277.
  112. Kalbitz, M., F. Fattahi, T.J. Herron, J.J. Grailer, L. Jajou, H. Lu, M. Huber-Lang, F.S. Zetoune, J.V. Sarma, S.M. Day, M.W. Russell, J. Jalife, and P.A. Ward. 2016. Complement Destabilizes Cardiomyocyte Function In Vivo after Polymicrobial Sepsis and In Vitro. J Immunol. 197:2353-2361.
  113. Kalbitz, M., F. Fattahi, J.J. Grailer, L. Jajou, E.A. Malan, F.S. Zetoune, M. Huber-Lang, M.W. Russell, and P.A. Ward. 2016. Complement-induced activation of the cardiac NLRP3 inflammasome in sepsis. FASEB J. 30:3997-4006.
  114. Jiang, D., J. Muschhammer, Y. Qi, A. Kugler, J.C. de Vries, M. Saffarzadeh, A. Sindrilaru, S.V. Beken, M. Wlaschek, M.A. Kluth, C. Ganss, N.Y. Frank, M.H. Frank, K.T. Preissner, and K. Scharffetter-Kochanek. 2016. Suppression of Neutrophil-Mediated Tissue Damage-A Novel Skill of Mesenchymal Stem Cells. Stem Cells. 34:2393-2406.
  115. Huber-Lang, M., F. Gebhard, C.Q. Schmidt, A. Palmer, S. Denk, and R. Wiegner. 2016. Complement therapeutic strategies in trauma, hemorrhagic shock and systemic inflammation - closing Pandora's box? Semin Immunol. 28:278-284.
  116. Heise, C., J.C. Schroeder, M. Schoen, S. Halbedl, D. Reim, S. Woelfle, M.R. Kreutz, M.J. Schmeisser, and T.M. Boeckers. 2016. Selective Localization of Shanks to VGLUT1-Positive Excitatory Synapses in the Mouse Hippocampus. Front Cell Neurosci. 10:106.
  117. Hartmann, K., M. Koenen, S. Schauer, S. Wittig-Blaich, M. Ahmad, U. Baschant, and J.P. Tuckermann. 2016. Molecular Actions of Glucocorticoids in Cartilage and Bone During Health, Disease, and Steroid Therapy. Physiol Rev. 96:409-447.
  118. Harder, M.J., M. Anliker, B. Hochsmann, T. Simmet, M. Huber-Lang, H. Schrezenmeier, D. Ricklin, J.D. Lambris, P.N. Barlow, and C.Q. Schmidt. 2016. Comparative Analysis of Novel Complement-Targeted Inhibitors, MiniFH, and the Natural Regulators Factor H and Factor H-like Protein 1 Reveal Functional Determinants of Complement Regulation. J Immunol. 196:866-876.
  119. Halbedl, S., M. Schoen, M.S. Feiler, T.M. Boeckers, and M.J. Schmeisser. 2016. Shank3 is localized in axons and presynaptic specializations of developing hippocampal neurons and involved in the modulation of NMDA receptor levels at axon terminals. J Neurochem. 137:26-32.
  120. Haffner-Luntzer, M., J. Kemmler, V. Heidler, K. Prystaz, T. Schinke, M. Amling, A. Kovtun, A.E. Rapp, A. Ignatius, and A. Liedert. 2016. Inhibition of Midkine Augments Osteoporotic Fracture Healing. PloS one. 11:e0159278.
  121. Haffner-Luntzer, M., A. Heilmann, A.E. Rapp, R. Roessler, T. Schinke, M. Amling, A. Ignatius, and A. Liedert. 2016. Antagonizing Midkine Accelerates Fracture Healing in Mice by Enhanced Bone Formation in the Fracture Callus. Br J Pharmacol. 173:2237-2249.
  122. Gey, M., R. Wanner, C. Schilling, M.T. Pedro, D. Sinske, and B. Knöll. 2016. Atf3 mutant mice show reduced axon regeneration and impaired regeneration-associated gene induction after peripheral nerve injury. Open Biol. 6.
  123. Falkner, S., S. Grade, L. Dimou, K.K. Conzelmann, T. Bonhoeffer, M. Gotz, and M. Hubener. 2016. Transplanted embryonic neurons integrate into adult neocortical circuits. Nature. 539:248-253.
  124. Eiseler, T., C. Wille, C. Koehler, A. Illing, and T. Seufferlein. 2016. Protein Kinase D2 Assembles a Multiprotein Complex at the Trans-Golgi Network to Regulate Matrix Metalloproteinase Secretion. J Biol Chem. 291:462-477.
  125. Ehrnthaller, C., M. Huber-Lang, A. Kovtun, A.E. Rapp, J. Kemmler, F. Gebhard, and A. Ignatius. 2016. C5aR inhibition in the early inflammatory phase does not affect bone regeneration in a model of uneventful fracture healing. European Journal of Medical Research. 21:42.
  126. Asfar, P., J.A. Russell, J. Tuckermann, and P. Radermacher. 2016. Selepressin in Septic Shock: A Step Toward Decatecholaminization? Crit Care Med. 44:234-236.
  127. Anastasiadou, S., and B. Knöll. 2016. The multiple sclerosis drug fingolimod (FTY720) stimulates neuronal gene expression, axonal growth and regeneration. Exp Neurol. 279:243-260.
  128. Xu, P., P. Fischer-Posovszky, J. Bischof, P. Radermacher, M. Wabitsch, D. Henne-Bruns, A.-M. Wolf, A. Hillenbrand, and U. Knippschild. 2015. Gene expression levels of Casein kinase 1 (CK1) isoforms are correlated to adiponectin levels in adipose tissue of morbid obese patients and site-specific phosphorylation mediated by CK1 influences multimerization of adiponectin. Molecular and Cellular Endocrinology. 406:87-101.
  129. Wehner, D., C. Jahn, and G. Weidinger. 2015. Use of the TetON System to Study Molecular Mechanisms of Zebrafish Regeneration. J Vis Exp:e52756.
  130. Wagner, K., M. Groger, O. McCook, A. Scheuerle, P. Asfar, B. Stahl, M. Huber-Lang, A. Ignatius, B. Jung, M. Duechs, P. Moller, M. Georgieff, E. Calzia, P. Radermacher, and F. Wagner. 2015. Blunt Chest Trauma in Mice after Cigarette Smoke-Exposure: Effects of Mechanical Ventilation with 100 % O2. PloS one. 10:e0132810.
  131. Vogl, A.M., M.M. Brockmann, S.A. Giusti, G. Maccarrone, C.A. Vercelli, C.A. Bauder, J.S. Richter, F. Roselli, A.S. Hafner, N. Dedic, C.T. Wotjak, D.M. Vogt-Weisenhorn, D. Choquet, C.W. Turck, V. Stein, J.M. Deussing, and D. Refojo. 2015. Neddylation inhibition impairs spine development, destabilizes synapses and deteriorates cognition. Nat Neurosci. 18:239-251.
  132. Vettorazzi, S., C. Bode, L. Dejager, L. Frappart, E. Shelest, C. Klassen, A. Tasdogan, H.M. Reichardt, C. Libert, M. Schneider, F. Weih, N. Henriette Uhlenhaut, J.P. David, M. Graler, A. Kleiman, and J.P. Tuckermann. 2015. Glucocorticoids limit acute lung inflammation in concert with inflammatory stimuli by induction of SphK1. Nat Commun. 6:7796.
  133. Theiss-Suennemann, J., K. Jorss, J.J. Messmann, S.D. Reichardt, E. Montes-Cobos, F. Luhder, J.P. Tuckermann, A.W. H, R. Dressel, H.J. Grone, G. Strauss, and H.M. Reichardt. 2015. Glucocorticoids attenuate acute graft-versus-host disease by suppressing the cytotoxic capacity of CD8(+) T cells. J Pathol. 235:646-655.
  134. Sirko, S., M. Irmler, S. Gascon, S. Bek, S. Schneider, L. Dimou, J. Obermann, D. De Souza Paiva, F. Poirier, J. Beckers, S.M. Hauck, Y.A. Barde, and M. Gotz. 2015. Astrocyte reactivity after brain injury-: The role of galectins 1 and 3. Glia. 63:2340-2361.
  135. Singh, K., P. Maity, L. Krug, P. Meyer, N. Treiber, T. Lucas, A. Basu, S. Kochanek, M. Wlaschek, H. Geiger, and K. Scharffetter-Kochanek. 2015. Superoxide anion radicals induce IGF-1 resistance through concomitant activation of PTP1B and PTEN. EMBO Mol Med. 7:59-77.
  136. Schatton, T., J. Yang, S. Kleffel, M. Uehara, S.R. Barthel, C. Schlapbach, Q. Zhan, S. Dudeney, H. Mueller, N. Lee, J.C. de Vries, B. Meier, S. Vander Beken, M.A. Kluth, C. Ganss, A.H. Sharpe, A.M. Waaga-Gasser, M.H. Sayegh, R. Abdi, K. Scharffetter-Kochanek, G.F. Murphy, T.S. Kupper, N.Y. Frank, and M.H. Frank. 2015. ABCB5 Identifies Immunoregulatory Dermal Cells. Cell Rep. 12:1564-1574.
  137. Messmann, J.J., T. Reisser, F. Leithauser, M.B. Lutz, K.M. Debatin, and G. Strauss. 2015. In vitro-generated MDSCs prevent murine GVHD by inducing type 2 T cells without disabling antitumor cytotoxicity. Blood. 126:1138-1148.
  138. Langgartner, D., A.M. Fuchsl, N. Uschold-Schmidt, D.A. Slattery, and S.O. Reber. 2015. Chronic subordinate colony housing paradigm: a mouse model to characterize the consequences of insufficient glucocorticoid signaling. Front Psychiatry. 6:18.
  139. Kemmler, J., R. Bindl, O. McCook, F. Wagner, M. Groger, K. Wagner, A. Scheuerle, P. Radermacher, and A. Ignatius. 2015. Exposure to 100% Oxygen Abolishes the Impairment of Fracture Healing after Thoracic Trauma. PloS one. 10:e0131194.
  140. Kalbitz, M., J.J. Grailer, F. Fattahi, L. Jajou, T.J. Herron, K.F. Campbell, F.S. Zetoune, M. Bosmann, J.V. Sarma, M. Huber-Lang, F. Gebhard, R. Loaiza, H.H. Valdivia, J. Jalife, M.W. Russell, and P.A. Ward. 2015. Role of extracellular histones in the cardiomyopathy of sepsis. FASEB J. 29:2185-2193.
  141. Jiang, D., and K. Scharffetter-Kochanek. 2015. Mesenchymal Stem Cells in Wound Repair, Tissue Homeostasis, and Aging. In Stem Cell Aging: Mechanisms, Consequences, Rejuvenation. H. Geiger, H. Jasper, and M. Florian, editors. Springer, Vienna. 287-318.
  142. Hafner, S., K. Wagner, M. Wepler, J. Matallo, M. Groger, O. McCook, A. Scheuerle, M. Huber-Lang, M. Frick, S. Weber, B. Stahl, B. Jung, E. Calzia, M. Georgieff, P. Moller, P. Dietl, P. Radermacher, and F. Wagner. 2015. Physiological and immune-biological characterization of a long-term murine model of blunt chest trauma. Shock. 43:140-147.
  143. Hafner, S., F. Beloncle, A. Koch, P. Radermacher, and P. Asfar. 2015. Hyperoxia in intensive care, emergency, and peri-operative medicine: Dr. Jekyll or Mr. Hyde? A 2015 update. Ann Intensive Care. 5:42.
  144. Denk, S., R. Wiegner, F.M. Hones, D.A. Messerer, P. Radermacher, M. Weiss, M. Kalbitz, C. Ehrnthaller, S. Braumuller, O. McCook, F. Gebhard, S. Weckbach, and M. Huber-Lang. 2015. Early Detection of Junctional Adhesion Molecule-1 (JAM-1) in the Circulation after Experimental and Clinical Polytrauma. Mediators Inflamm. 2015:463950.
  145. Barth, H., S. Fischer, A. Moglich, and C. Fortsch. 2015. Clostridial C3 Toxins Target Monocytes/Macrophages and Modulate Their Functions. Front Immunol. 6:339.
  146. Asfar, P., M. Singer, and P. Radermacher. 2015. Understanding the benefits and harms of oxygen therapy. Intensive Care Med. 41:1118-1121.
  147. Asfar, P., and P. Radermacher. 2015. Drug-Induced "Suspended Animation": Can a Dream Become True? Crit Care Med. 43:1528-1530.
  148. Anastasiadou, S., S. Liebenehm, D. Sinske, C. Meyer zu Reckendorf, B. Moepps, A. Nordheim, and B. Knöll. 2015. Neuronal expression of the transcription factor serum response factor modulates myelination in a mouse multiple sclerosis model. Glia. 63:958-976.
  149. Witte, J., W. Kahler, T. Wunderlich, P. Radermacher, C. Wohlrab, and A. Koch. 2014. Dose-time dependency of hyperbaric hyperoxia-induced DNA strand breaks in human immune cells visualized with the comet assay. Undersea Hyperb Med. 41:171-181.
  150. Wehner, D., W. Cizelsky, M.D. Vasudevaro, G. Ozhan, C. Haase, B. Kagermeier-Schenk, A. Roder, R.I. Dorsky, E. Moro, F. Argenton, M. Kuhl, and G. Weidinger. 2014. Wnt/beta-catenin signaling defines organizing centers that orchestrate growth and differentiation of the regenerating zebrafish caudal fin. Cell Rep. 6:467-481.
  151. Vogt, J.A., U. Wachter, K. Wagner, E. Calzia, M. Groger, S. Weber, B. Stahl, M. Georgieff, P. Asfar, E. Fontaine, P. Radermacher, X.M. Leverve, and F. Wagner. 2014. Effects of glycemic control on glucose utilization and mitochondrial respiration during resuscitated murine septic shock. Intensive Care Med Exp. 2:19.
  152. Qi, Y., D. Jiang, A. Sindrilaru, A. Stegemann, S. Schatz, N. Treiber, M. Rojewski, H. Schrezenmeier, S. Vander Beken, M. Wlaschek, M. Bohm, A. Seitz, N. Scholz, L. Dürselen, J. Brinckmann, A. Ignatius, and K. Scharffetter-Kochanek. 2014. TSG-6 released from intradermally injected mesenchymal stem cells accelerates wound healing and reduces tissue fibrosis in murine full-thickness skin wounds. J Invest Dermatol. 134:526-537.
  153. McCook, O., P. Radermacher, C. Volani, P. Asfar, A. Ignatius, J. Kemmler, P. Moller, C. Szabo, M. Whiteman, M.E. Wood, R. Wang, M. Georgieff, and U. Wachter. 2014. H2S during circulatory shock: Some unresolved questions. Nitric oxide : biology and chemistry / official journal of the Nitric Oxide Society. 41:48-61.
  154. Lehnert, C., M. Weiswange, I. Jeremias, C. Bayer, M. Grunert, K.M. Debatin, and G. Strauss. 2014. TRAIL-receptor costimulation inhibits proximal TCR signaling and suppresses human T cell activation and proliferation. J Immunol. 193:4021-4031.
  155. Haffner-Luntzer, M., A. Heilmann, A. Rapp, S. Beie, T. Schinke, M. Amling, A. Ignatius, and A. Liedert. 2014. Midkine Deficiency Delays Chondrogenesis during the Early Phase of Fracture Healing in Mice PloS one. 9:e116282.
  156. Geurtzen, K., F. Knopf, D. Wehner, L.F. Huitema, S. Schulte-Merker, and G. Weidinger. 2014. Mature osteoblasts dedifferentiate in response to traumatic bone injury in the zebrafish fin and skull. Development. 141:2225-2234.
  157. Eisenbacher, J.L., H. Schrezenmeier, B. Jahrsdorfer, C. Kaltenmeier, M.T. Rojewski, T. Yildiz, T. Beyer, A. Erle, D.S. Wiegmann, S. Grassl, R. Hang, S. Korper, M. Wiesneth, M.T. Lotze, and R. Lotfi. 2014. S100A4 and uric acid promote mesenchymal stromal cell induction of IL-10+/IDO+ lymphocytes. J Immunol. 192:6102-6110.
  158. Stern, S., S. Haverkamp, D. Sinske, A. Tedeschi, U. Naumann, S. Di Giovanni, S. Kochanek, A. Nordheim, and B. Knöll. 2013. The transcription factor serum response factor stimulates axon regeneration through cytoplasmic localization and cofilin interaction. J Neurosci. 33:18836-18848.
  159. Sirko, S., G. Behrendt, P.A. Johansson, P. Tripathi, M. Costa, S. Bek, C. Heinrich, S. Tiedt, D. Colak, M. Dichgans, I.R. Fischer, N. Plesnila, M. Staufenbiel, C. Haass, M. Snapyan, A. Saghatelyan, L.H. Tsai, A. Fischer, K. Grobe, L. Dimou, and M. Gotz. 2013. Reactive glia in the injured brain acquire stem cell properties in response to sonic hedgehog. [corrected]. Cell Stem Cell. 12:426-439.
  160. Sindrilaru, A., and K. Scharffetter-Kochanek. 2013. Disclosure of the Culprits: Macrophages-Versatile Regulators of Wound Healing. Adv Wound Care (New Rochelle). 2:357-368.
  161. Seichter, F., A. Wilk, K. Worle, S.S. Kim, J.A. Vogt, U. Wachter, P. Radermacher, and B. Mizaikoff. 2013. Multivariate determination of 13CO2/12CO2 ratios in exhaled mouse breath with mid-infrared hollow waveguide gas sensors. Anal Bioanal Chem. 405:4945-4951.
  162. Saxena, S., F. Roselli, K. Singh, K. Leptien, J.P. Julien, F. Gros-Louis, and P. Caroni. 2013. Neuroprotection through excitability and mTOR required in ALS motoneurons to delay disease and extend survival. Neuron. 80:80-96.
  163. Maqbool, A., M. Lattke, T. Wirth, and B. Baumann. 2013. Sustained, neuron-specific IKK/NF-kappaB activation generates a selective neuroinflammatory response promoting local neurodegeneration with aging. Mol Neurodegener. 8:40.
  164. Keuper, M., I. Wernstedt Asterholm, P.E. Scherer, M.A. Westhoff, P. Moller, K.M. Debatin, G. Strauss, M. Wabitsch, and P. Fischer-Posovszky. 2013. TRAIL (TNF-related apoptosis-inducing ligand) regulates adipocyte metabolism by caspase-mediated cleavage of PPARgamma. Cell Death Dis. 4:e474.
  165. Jiang, D., Y. Qi, N.G. Walker, A. Sindrilaru, A. Hainzl, M. Wlaschek, S. MacNeil, and K. Scharffetter-Kochanek. 2013. The effect of adipose tissue derived MSCs delivered by a chemically defined carrier on full-thickness cutaneous wound healing. Biomaterials. 34:2501-2515.
  166. Hartmann, N., J.J. Messmann, F. Leithauser, M. Weiswange, M. Kluge, H. Fricke, K.M. Debatin, and G. Strauss. 2013. Recombinant CD95-Fc (APG101) prevents graft-versus-host disease in mice without disabling antitumor cytotoxicity and T-cell functions. Blood. 121:556-565.
  167. Grotek, B., D. Wehner, and G. Weidinger. 2013. Notch signaling coordinates cellular proliferation with differentiation during zebrafish fin regeneration. Development. 140:1412-1423.
  168. Bardehle, S., M. Kruger, F. Buggenthin, J. Schwausch, J. Ninkovic, H. Clevers, H.J. Snippert, F.J. Theis, M. Meyer-Luehmann, I. Bechmann, L. Dimou, and M. Gotz. 2013. Live imaging of astrocyte responses to acute injury reveals selective juxtavascular proliferation. Nat Neurosci. 16:580-586.
  169. Schmeisser, M.J., B. Baumann, S. Johannsen, G.F. Vindedal, V. Jensen, O.C. Hvalby, R. Sprengel, J. Seither, A. Maqbool, A. Magnutzki, M. Lattke, F. Oswald, T.M. Boeckers, and T. Wirth. 2012. IkappaB kinase/nuclear factor kappaB-dependent insulin-like growth factor 2 (Igf2) expression regulates synapse formation and spine maturation via Igf2 receptor signaling. J Neurosci. 32:5688-5703.
  170. Kleiman, A., S. Hubner, J.M. Rodriguez Parkitna, A. Neumann, S. Hofer, M.A. Weigand, M. Bauer, W. Schmid, G. Schutz, C. Libert, H.M. Reichardt, and J.P. Tuckermann. 2012. Glucocorticoid receptor dimerization is required for survival in septic shock via suppression of interleukin-1 in macrophages. FASEB J. 26:722-729.
  171. Ehrnthaller, C., U. Amara, S. Weckbach, M. Kalbitz, M. Huber-Lang, and S. Bahrami. 2012. Alteration of complement hemolytic activity in different trauma and sepsis models. J Inflamm Res. 5:59-66.
  172. Dyson, A., F. Simon, A. Seifritz, O. Zimmerling, J. Matallo, E. Calzia, P. Radermacher, and M. Singer. 2012. Bladder tissue oxygen tension monitoring in pigs subjected to a range of cardiorespiratory and pharmacological challenges. Intensive Care Med. 38:1868-1876.
  173. Burk, A.M., M. Martin, M.A. Flierl, D. Rittirsch, M. Helm, L. Lampl, U. Bruckner, G.L. Stahl, A.M. Blom, M. Perl, F. Gebhard, and M. Huber-Lang. 2012. Early complementopathy after multiple injuries in humans. Shock. 37:348-354.
  174. Sindrilaru, A., T. Peters, S. Wieschalka, C. Baican, A. Baican, H. Peter, A. Hainzl, S. Schatz, Y. Qi, A. Schlecht, J.M. Weiss, M. Wlaschek, C. Sunderkotter, and K. Scharffetter-Kochanek. 2011. An unrestrained proinflammatory M1 macrophage population induced by iron impairs wound healing in humans and mice. J Clin Invest. 121:985-997.
  175. Simon, C., M. Gotz, and L. Dimou. 2011. Progenitors in the adult cerebral cortex: cell cycle properties and regulation by physiological stimuli and injury. Glia. 59:869-881.
  176. Shang, X., J.A. Cancelas, L. Li, F. Guo, W. Liu, J.F. Johnson, A. Ficker, D. Daria, H. Geiger, N. Ratner, and Y. Zheng. 2011. R-Ras and Rac GTPase cross-talk regulates hematopoietic progenitor cell migration, homing, and mobilization. J Biol Chem. 286:24068-24078.
  177. Kohler, A., H. Geiger, and M. Gunzer. 2011. Imaging hematopoietic stem cells in the marrow of long bones in vivo. Methods Mol Biol. 750:215-224.
  178. Knopf, F., C. Hammond, A. Chekuru, T. Kurth, S. Hans, C.W. Weber, G. Mahatma, S. Fisher, M. Brand, S. Schulte-Merker, and G. Weidinger. 2011. Bone regenerates via dedifferentiation of osteoblasts in the zebrafish fin. Dev Cell. 20:713-724.
  179. Boda, E., F. Vigano, P. Rosa, M. Fumagalli, V. Labat-Gest, F. Tempia, M.P. Abbracchio, L. Dimou, and A. Buffo. 2011. The GPR17 receptor in NG2 expressing cells: focus on in vivo cell maturation and participation in acute trauma and chronic damage. Glia. 59:1958-1973.
  180. Ryan, M.A., K.J. Nattamai, E. Xing, D. Schleimer, D. Daria, A. Sengupta, A. Kohler, W. Liu, M. Gunzer, M. Jansen, N. Ratner, T.D. Le Cras, A. Waterstrat, G. Van Zant, J.A. Cancelas, Y. Zheng, and H. Geiger. 2010. Pharmacological inhibition of EGFR signaling enhances G-CSF-induced hematopoietic stem cell mobilization. Nat Med. 16:1141-1146.
  181. Baumgart, K., F. Wagner, M. Groger, S. Weber, E. Barth, J.A. Vogt, U. Wachter, M. Huber-Lang, M.W. Knoferl, G. Albuszies, M. Georgieff, P. Asfar, C. Szabo, E. Calzia, P. Radermacher, and V. Simkova. 2010. Cardiac and metabolic effects of hypothermia and inhaled hydrogen sulfide in anesthetized and ventilated mice. Crit Care Med. 38:588-595.