Zusammenstellung von Bildern aus dem Sonderforschungsbereich

2019

226.
M. Gröger, M. Wepler, U. Wachter, T. Merz, O. McCook, S. Kress, B. Lukaschewski, S. Häfner, M. Huber-Lang, E. Calzia, M. Georgieff, N. Nagahara, C. Szabo, P. Radermacher and C. Hartmann, "The Effects of Genetic 3-Mercaptopyruvate Sulfurtransferase Deficiency in Murine Traumatic-Hemorrhagic Shock", Shock, vol. 51, no. 4, pp. 472-478, 2019.
DOI:10.1097/SHK.0000000000001165
Datei:pdfhttps://www.ncbi.nlm.nih.gov/pubmed/29668565 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6192867/pdf/nihms959306.pdf
225.
M. Wepler, T. Merz, U. Wachter, J. Vogt, E. Calzia, A. Scheuerle, P. Möller, M. Gröger, S. Kress, M. Fink, B. Lukaschewski, G. Rumm, B. Stahl, M. Georgieff, M. Huber-Lang, R. Torregrossa, M. Whiteman, O. McCook, P. Radermacher and C. Hartmann, "The Mitochondria-Targeted H2S-Donor AP39 in a Murine Model of Combined Hemorrhagic Shock and Blunt Chest Trauma", Shock, vol. 52, no. 2, pp. 230-239, 2019.
DOI:10.1097/SHK.0000000000001210
Datei:https://www.ncbi.nlm.nih.gov/pubmed/29927788
224.
I. Lackner, B. Weber, M. Baur, M. Haffner-Luntzer, T. Eiseler, G. Fois, F. Gebhard, B. Relja, I. Marzi, R. Pfeifer, S. Halvachizadeh, M. Lipiski, N. Cesarovic, H. C. Pape, M. Kalbitz and T. R. Group, "Midkine Is Elevated After Multiple Trauma and Acts Directly on Human Cardiomyocytes by Altering Their Functionality and Metabolism", Front Immunol, vol. 10, pp. 1920, 2019.
DOI:10.3389/fimmu.2019.01920
Datei:pdfhttps://www.ncbi.nlm.nih.gov/pubmed/31552013 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6736577/pdf/fimmu-10-01920.pdf
223.
F. Roselli and M. Huber-Lang, "TREM1-ors shake the brain and gut after stroke", Nat Immunol, vol. 20, no. 8, pp. 950-952, 2019.
DOI:10.1038/s41590-019-0443-9
Datei:pdfhttps://www.ncbi.nlm.nih.gov/pubmed/31285627 https://www.nature.com/articles/s41590-019-0443-9.pdf
222.
B. Weber, I. Lackner, M. Haffner-Luntzer, A. Palmer, J. Pressmar, K. Scharffetter-Kochanek, B. Knöll, H. Schrezenmeier, B. Relja and M. Kalbitz, "Modeling trauma in rats: similarities to humans and potential pitfalls to consider", J Transl Med, vol. 17, no. 1, pp. 305, 2019.
DOI:10.1186/s12967-019-2052-7
Datei:https://doi.org/10.1186/s12967-019-2052-7
221.
B. Weber, M. R. Mendler, I. Lackner, J. Pressmar, M. Haffner-Luntzer, S. Hofler, C. Braun, H. Hummler, S. Schwarz and M. Kalbitz, "Tissue damage in the heart after cardiac arrest induced by asphyxia and hemorrhage in newborn pigs", Pediatr Res, vol. 86, no. 6, pp. 709-718, 2019.
DOI:10.1038/s41390-019-0505-6
Datei:https://www.ncbi.nlm.nih.gov/pubmed/31336381
220.
B. Weber, M. R. Mendler, I. Lackner, A. Zelewski, S. Hofler, M. Baur, C. K. Braun, H. Hummler, S. Schwarz, J. Pressmar and M. Kalbitz, "Lung injury after asphyxia and hemorrhagic shock in newborn piglets: Analysis of structural and inflammatory changes", Plos One, vol. 14, no. 7, pp. 14, 2019.
DOI:10.1371/journal.pone.0219211
Datei:
219.
L. Escoter-Torres, G. Caratti, A. Mechtidou, J. Tuckermann, N. H. Uhlenhaut and S. Vettorazzi, "Fighting the Fire: Mechanisms of Inflammatory Gene Regulation by the Glucocorticoid Receptor", Front Immunol, vol. 10, pp. 1859, 2019.
DOI:10.3389/fimmu.2019.01859
Datei:pdfhttps://www.ncbi.nlm.nih.gov/pubmed/31440248 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6693390/pdf/fimmu-10-01859.pdf
218.
H. P. Muller, D. Brenner, F. Roselli, D. Wiesner, A. Abaei, M. Gorges, K. M. Danzer, A. C. Ludolph, W. Tsao, P. C. Wong, V. Rasche, J. H. Weishaupt and J. Kassubek, "Longitudinal diffusion tensor magnetic resonance imaging analysis at the cohort level reveals disturbed cortical and callosal microstructure with spared corticospinal tract in the TDP-43 (G298S) ALS mouse model", Transl Neurodegener, vol. 8, pp. 27, 2019.
DOI:10.1186/s40035-019-0163-y
Datei:pdfhttps://www.ncbi.nlm.nih.gov/pubmed/31485326 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6716821/pdf/40035_2019_Article_163.pdf
217.
M. Haffner-Luntzer, K. D. Hankenson, A. Ignatius, R. Pfeifer, B. A. Khader, F. Hildebrand, M. Griensven, H. C. Pape and M. Lehmicke, "A Review of Animal Models of Comorbidities in Fracture-Healing Research", J Orthop Res, vol. 37, no. 12, pp. 2491-2498, 2019.
DOI:10.1002/jor.24454
Datei:https://www.ncbi.nlm.nih.gov/pubmed/31444806
216.
T. O'Connor, X. Zhou, J. Kosla, A. Adili, M. Garcia Beccaria, E. Kotsiliti, D. Pfister, A. L. Johlke, A. Sinha, R. Sankowski, M. Schick, R. Lewis, N. Dokalis, B. Seubert, B. Hochst, D. Inverso, D. Heide, W. Zhang, P. Weihrich, K. Manske, D. Wohlleber, M. Anton, A. Hoellein, G. Seleznik, J. Bremer, S. Bleul, H. G. Augustin, F. Scherer, U. Koedel, A. Weber, U. Protzer, R. Förster, T. Wirth, A. Aguzzi, F. Meissner, M. Prinz, B. Baumann, U. E. Hopken, P. A. Knolle, L. Baumgarten, U. Keller and M. Heikenwalder, "Age-Related Gliosis Promotes Central Nervous System Lymphoma through CCL19-Mediated Tumor Cell Retention", Cancer Cell, vol. 36, no. 3, pp. 250-267 e9, 2019.
DOI:10.1016/j.ccell.2019.08.001
Datei:https://www.ncbi.nlm.nih.gov/pubmed/31526758
215.
T. Datzmann, M. Wepler, U. Wachter, J. A. Vogt, O. McCook, T. Merz, E. Calzia, M. Gröger, C. Hartmann, P. Asfar, P. Radermacher and B. L. Nussbaum, "Cardiac Effects of Hyperoxia During Resuscitation From Hemorrhagic Shock in Swine", Shock, vol. 52, no. 4, pp. e52-e59, 2019.
DOI:10.1097/SHK.0000000000001283
Datei:https://www.ncbi.nlm.nih.gov/pubmed/30407373
214.
F. Haussner, S. Chakraborty, R. Halbgebauer and M. Huber-Lang, "Challenge to the Intestinal Mucosa During Sepsis", Front Immunol, vol. 10, pp. 891, 2019.
DOI:10.3389/fimmu.2019.00891
Datei:pdfhttps://www.ncbi.nlm.nih.gov/pubmed/31114571 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6502990/pdf/fimmu-10-00891.pdf
213.
M. Haffner-Luntzer, S. Foertsch, V. Fischer, K. Prystaz, M. Tschaffon, Y. Mödinger, C. S. Bahney, R. S. Marcucio, T. Miclau, A. Ignatius and S. O. Reber, "Chronic psychosocial stress compromises the immune response and endochondral ossification during bone fracture healing via β-AR signaling", Proc Natl Acad Sci U S A, vol. 116, no. 117, pp. 8615-8622, 2019.
DOI:10.1073/pnas.1819218116
212.
M. Vogel, H. Christow, I. Manz, M. Denkinger, A. Amoah, D. Schutz, A. Brown, B. Mohrle, A. Schaffer, M. Kalbitz, F. Gebhard, B. Mayer, M. Huber-Lang and H. Geiger, "Distinct Dynamics of Stem and Progenitor Cells in Blood of Polytraumatized Patients", Shock, vol. 51, no. 4, pp. 430-438, 2019.
DOI:10.1097/SHK.0000000000001198
Datei:pdfhttps://www.ncbi.nlm.nih.gov/pubmed/30289853 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6407807/pdf/shk-51-430.pdf
211.
D. Langgartner, U. Wachter, C. Hartmann, M. Gröger, J. Vogt, T. Merz, O. McCook, M. Fink, S. Kress, M. Georgieff, J. F. Kunze, P. L. Radermacher, S. O. Reber and M. Wepler, "Effects of Psychosocial Stress on Subsequent Hemorrhagic Shock and Resuscitation in Male Mice", Shock, vol. 51, no. 6, pp. 725-730, 2019.
DOI:10.1097/SHK.0000000000001204
Datei:https://www.ncbi.nlm.nih.gov/pubmed/29889818
210.
P. Pfänder, M. Fidan, U. Burret, L. Lipinski and S. Vettorazzi, "Cdk5 Deletion Enhances the Anti-inflammatory Potential of GC-Mediated GR Activation During Inflammation", Front Immunol, vol. 10, pp. 1554, 2019.
DOI:10.3389/fimmu.2019.01554
Datei:pdfhttps://www.ncbi.nlm.nih.gov/pubmed/31354714 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6635475/pdf/fimmu-10-01554.pdf
209.
L. Weert, J. C. Buurstede, H. C. M. Sips, S. Vettorazzi, I. M. Mol, J. Hartmann, S. Prekovic, W. Zwart, M. V. Schmidt, B. Roozendaal, J. P. Tuckermann, R. A. Sarabdjitsingh and O. C. Meijer, "Identification of mineralocorticoid receptor target genes in the mouse hippocampus", J Neuroendocrinol, vol. 31, no. 8, pp. e12735, 2019.
DOI:10.1111/jne.12735
Datei:pdfhttps://www.ncbi.nlm.nih.gov/pubmed/31121060 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6771480/pdf/JNE-31-na.pdf
208.
K. Schuetze, A. Eickhoff, C. Dehner, F. Gebhard and P. H. Richter, "Impact of oral anticoagulation on proximal femur fractures treated within 24 h - A retrospective chart review", Injury, vol. 50, no. 11, pp. 2040-2044, 2019.
DOI:10.1016/j.injury.2019.09.011
Datei:https://www.ncbi.nlm.nih.gov/pubmed/31543315
207.
M. Wepler, J. M. Preuss, T. Merz, C. Hartmann, U. Wachter, O. McCook, J. Vogt, S. Kress, M. Gröger, M. Fink, A. Scheuerle, P. Möller, E. Calzia, U. Burret, P. Radermacher, J. P. Tuckermann and S. Vettorazzi, "Impaired Glucocorticoid Receptor Dimerization Aggravates LPS-Induced Circulatory and Pulmonary Dysfunction", Front Immunol, vol. 10, pp. 3152, 2019.
DOI:10.3389/fimmu.2019.03152
Datei:https://www.ncbi.nlm.nih.gov/pubmed/32038649
206.
N. Tappenbeck, H. M. Schroder, E. Niebergall-Roth, F. Hassinger, U. Dehio, K. Dieter, K. Kraft, A. Kerstan, J. Esterlechner, N. Y. Frank, K. Scharffetter-Kochanek, G. F. Murphy, D. P. Orgill, J. Beck, M. H. Frank, C. Ganss and M. A. Kluth, "In vivo safety profile and biodistribution of GMP-manufactured human skin-derived ABCB5-positive mesenchymal stromal cells for use in clinical trials", Cytotherapy, vol. 21, no. 5, pp. 546-560, 2019.
DOI:10.1016/j.jcyt.2018.12.005
Datei:pdfhttps://www.ncbi.nlm.nih.gov/pubmed/30878384 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6513723/pdf/nihms-1027450.pdf
205.
C. Hartmann, M. Gröger, J. P. Noirhomme, A. Scheuerle, P. Möller, U. Wachter, M. Huber-Lang, B. Nussbaum, B. Jung, T. Merz, O. McCook, S. Kress, B. Stahl, E. Calzia, M. Georgieff, P. Radermacher and M. Wepler, "In-Depth Characterization of the Effects of Cigarette Smoke Exposure on the Acute Trauma Response and Hemorrhage in Mice", Shock, vol. 51, no. 1, pp. 68-77, 2019.
DOI:10.1097/SHK.0000000000001115
Datei:https://www.ncbi.nlm.nih.gov/pubmed/29424792
204.
V. E. Winkelmann, K. E. Thompson, K. Neuland, A. M. Jaramillo, G. Fois, H. Schmidt, O. H. Wittekindt, W. Han, M. J. Tuvim, B. F. Dickey, P. Dietl and M. Frick, "Inflammation-induced upregulation of P2X4 expression augments mucin secretion in airway epithelia", Am J Physiol Lung Cell Mol Physiol, vol. 316, no. 1, pp. L58-L70, 2019.
DOI:10.1152/ajplung.00157.2018
Datei:https://www.ncbi.nlm.nih.gov/pubmed/30358443 https://journals.physiology.org/doi/pdf/10.1152/ajplung.00157.2018
203.
E. M. Amann, A. Groß, M. T. Rojewski, H. A. Kestler, M. Kalbitz, R. E. Brenner, M. Huber-Lang and H. Schrezenmeier, "Inflammatory response of mesenchymal stromal cells after in vivo exposure with selected trauma-related factors and polytrauma serum", PLoS One, vol. 14, no. 5, pp. e0216862, 2019.
DOI:10.1371/journal.pone.0216862
Datei:pdfhttps://www.ncbi.nlm.nih.gov/pubmed/31086407 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6516676/pdf/pone.0216862.pdf
202.
M. Wlaschek, K. Singh, A. Sindrilaru, D. Crisan and K. Scharffetter-Kochanek, "Iron and iron-dependent reactive oxygen species in the regulation of macrophages and fibroblasts in non-healing chronic wounds", Free Radic Biol Med, vol. 133, pp. 262-275, 2019.
DOI:10.1016/j.freeradbiomed.2018.09.036
Datei:https://www.ncbi.nlm.nih.gov/pubmed/30261274