Publikationen aus dem SFB 1149
2021
364.
D. A. C. Messerer,
R. Halbgebauer,
B. Nilsson,
H. Pavenstadt,
P. Radermacher and
M. Huber-Lang,
"Immunopathophysiology of trauma-related acute kidney injury",
Nat Rev Nephrol,
vol. 17,
no. 2,
pp. 91-111,
2021.
DOI: | 10.1038/s41581-020-00344-9 |
Datei: | https://www.ncbi.nlm.nih.gov/pubmed/32958893 https://www.nature.com/articles/s41581-020-00344-9 |
363.
A. Magnutzki,
N. O. Alami,
M. Lattke,
T. M. Hein,
J. S. Scheller,
C. Kroger,
F. Oswald,
D. Yilmazer-Hanke,
T. Wirth and
B. Baumann,
"IKK2/NF-kappaB Activation in Astrocytes Reduces amyloid beta Deposition: A Process Associated with Specific Microglia Polarization",
Cells,
vol. 10,
no. 10,
pp. 2669,
2021.
DOI: | 10.3390/cells10102669 |
Datei: | https://www.ncbi.nlm.nih.gov/pubmed/34685649 https://mdpi-res.com/d_attachment/cells/cells-10-02669/article_deploy/cells-10-02669-v3.pdf |
362.
P. Maity,
K. Singh,
L. Krug,
A. Koroma,
A. Hainzl,
W. Bloch,
S. Kochanek,
M. Wlaschek,
M. Schorpp-Kistner,
P. Angel,
A. Ignatius,
H. Geiger and
K. Scharffetter-Kochanek,
"Persistent JunB activation in fibroblasts disrupts stem cell niche interactions enforcing skin aging",
Cell Rep,
vol. 36,
no. 9,
pp. 109634,
2021.
DOI: | 10.1016/j.celrep.2021.109634 |
Datei: | https://www.ncbi.nlm.nih.gov/pubmed/34469740 |
361.
F. Gärtner,
A. Gihring,
A. Roth,
J. Bischof,
P. Xu,
L. Elad,
M. Wabitsch,
T. Burster and
U. Knippschild,
"Obesity Prolongs the Inflammatory Response in Mice After Severe Trauma and Attenuates the Splenic Response to the Inflammatory Reflex",
Frontiers in Immunology,
vol. 12,
2021.
DOI: | 10.3389/fimmu.2021.745132 |
360.
A. Catanese,
S. Rajkumar,
D. Sommer,
D. Freisem,
A. Wirth,
A. Aly,
D. Massa-Lopez,
A. Olivieri,
F. Torelli,
V. Ioannidis,
J. Lipecka,
I. C. Guerrera,
D. Zytnicki,
A. Ludolph,
E. Kabashi,
M. A. Mulaw,
F. Roselli and
T. M. Böckers,
"Synaptic disruption and CREB-regulated transcription are restored by K(+) channel blockers in ALS",
EMBO Mol Med,
vol. 13,
no. 7,
pp. e13131,
2021.
DOI: | 10.15252/emmm.202013131 |
Datei: | https://www.ncbi.nlm.nih.gov/pubmed/34125498 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8261490/pdf/EMMM-13-e13131.pdf |
359.
K. Ernst,
A. K. Mittler,
V. Winkelmann,
C. Kling,
N. Eberhardt,
A. Anastasia,
M. Sonnabend,
R. Lochbaum,
J. Wirsching,
M. Sakari,
A. T. Pulliainen,
C. Skerry,
N. H. Carbonetti,
M. Frick and
H. Barth,
"Pharmacological targeting of host chaperones protects from pertussis toxin in vitro and in vivo",
Sci Rep,
vol. 11,
no. 1,
pp. 5429,
2021.
DOI: | 10.1038/s41598-021-84817-2 |
Datei: | https://www.ncbi.nlm.nih.gov/pubmed/33686161 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7940712/pdf/41598_2021_Article_84817.pdf |
358.
A. Maitz,
F. Haussner,
S. Braumuller,
A. Hoffmann,
L. Lupu,
U. Wachter,
P. Radermacher,
C. K. Braun,
H. J. Wilke,
M. Vogt,
A. Ignatius,
R. Halbgebauer,
L. Bettac,
T. F. E. Barth,
M. Huber-Lang and
A. Palmer,
"Temporal-spatial organ response after blast-induced experimental blunt abdominal trauma",
FASEB J,
vol. 35,
no. 12,
pp. e22038,
2021.
DOI: | 10.1096/fj.202100995R |
Datei: | https://www.ncbi.nlm.nih.gov/pubmed/34748229 https://faseb.onlinelibrary.wiley.com/doi/pdfdirect/10.1096/fj.202100995R?download=true |
357.
L. Debler,
A. Palmer,
S. Braumuller,
B. Klohs,
T. E. Mollnes,
K. Holzmann,
M. Huber-Lang and
R. Halbgebauer,
"Hemorrhagic Shock Induces a Rapid Transcriptomic Shift of the Immune Balance in Leukocytes after Experimental Multiple Injury",
Mediators Inflamm,
vol. 2021,
pp. 6654318,
2021.
DOI: | 10.1155/2021/6654318 |
Datei: | https://www.ncbi.nlm.nih.gov/pubmed/33574730 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7857921/pdf/MI2021-6654318.pdf |
356.
I. Sehring and
G. Weidinger,
"Zebrafish Fin: Complex Molecular Interactions and Cellular Mechanisms Guiding Regeneration",
Cold Spring Harb Perspect Biol,
2021.
DOI: | 10.1101/cshperspect.a040758 |
Datei: | https://www.ncbi.nlm.nih.gov/pubmed/34649924 |
355.
B. Weber,
I. Lackner,
F. Gebhard,
T. Miclau and
M. Kalbitz,
"Trauma, a Matter of the Heart-Molecular Mechanism of Post-Traumatic Cardiac Dysfunction",
Int J Mol Sci,
vol. 22,
no. 2,
pp. 737,
2021.
DOI: | 10.3390/ijms22020737 |
Datei: | https://www.ncbi.nlm.nih.gov/pubmed/33450984 https://mdpi-res.com/d_attachment/ijms/ijms-22-00737/article_deploy/ijms-22-00737.pdf |
354.
S. D. Reichardt,
A. Amouret,
C. Muzzi,
S. Vettorazzi,
F. Luhder and
H. M. Reichardt,
"The Role of Glucocorticoids in Inflammatory Diseases",
Cells,
vol. 10,
no. 11,
pp. 2921,
2021.
DOI: | 10.3390/cells10112921 |
Datei: | https://www.ncbi.nlm.nih.gov/pubmed/34831143 https://mdpi-res.com/d_attachment/cells/cells-10-02921/article_deploy/cells-10-02921.pdf |
353.
M. Lipcsey,
B. Persson,
O. Eriksson,
A. M. Blom,
K. Fromell,
M. Hultstrom,
M. Huber-Lang,
K. N. Ekdahl,
R. Frithiof and
B. Nilsson,
"The Outcome of Critically Ill COVID-19 Patients Is Linked to Thromboinflammation Dominated by the Kallikrein/Kinin System",
Front Immunol,
vol. 12,
pp. 627579,
2021.
DOI: | 10.3389/fimmu.2021.627579 |
Datei: | https://www.ncbi.nlm.nih.gov/pubmed/33692801 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7937878/pdf/fimmu-12-627579.pdf |
352.
M. Landenberger,
J. Nieland,
M. Roeder,
K. Norgaard,
P. Papatheodorou,
K. Ernst and
H. Barth,
"The cytotoxic effect of Clostridioides difficile pore-forming toxin CDTb",
Biochim Biophys Acta Biomembr,
vol. 1863,
no. 6,
pp. 183603,
2021.
DOI: | 10.1016/j.bbamem.2021.183603 |
Datei: | https://www.ncbi.nlm.nih.gov/pubmed/33689753 |
351.
J. Demiselle,
E. Calzia,
C. Hartmann,
D. A. C. Messerer,
P. Asfar,
P. Radermacher and
T. Datzmann,
"Target arterial PO2 according to the underlying pathology: a mini-review of the available data in mechanically ventilated patients",
Ann Intensive Care,
vol. 11,
no. 1,
pp. 88,
2021.
DOI: | 10.1186/s13613-021-00872-y |
Datei: | https://www.ncbi.nlm.nih.gov/pubmed/34076802 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8170650/pdf/13613_2021_Article_872.pdf |
350.
Z. Najafova,
P. Liu,
F. Wegwitz,
M. Ahmad,
L. Tamon,
R. L. Kosinsky,
W. Xie,
S. A. Johnsen and
J. Tuckermann,
"RNF40 exerts stage-dependent functions in differentiating osteoblasts and is essential for bone cell crosstalk",
Cell Death Differ,
vol. 28,
no. 2,
pp. 700-714,
2021.
DOI: | 10.1038/s41418-020-00614-w |
Datei: | https://www.ncbi.nlm.nih.gov/pubmed/32901120 https://www.nature.com/articles/s41418-020-00614-w.pdf |
349.
I. Lackner,
B. Weber,
M. Haffner-Luntzer,
S. Hristova,
F. Gebhard,
C. Lam,
K. Morioka,
R. S. Marcucio,
T. Miclau and
M. Kalbitz,
"Systemic and local cardiac inflammation after experimental long bone fracture, traumatic brain injury and combined trauma in mice",
J Orthop Translat,
vol. 28,
pp. 39-46,
2021.
DOI: | 10.1016/j.jot.2020.12.003 |
Datei: | https://www.ncbi.nlm.nih.gov/pubmed/33717980 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7906881/pdf/main.pdf |
348.
A. Elson,
M. Stein,
G. Rabie,
M. Barnea-Zohar,
S. Winograd-Katz,
N. Reuven,
M. Shalev,
J. Sekeres,
M. Kanaan,
J. Tuckermann and
B. Geiger,
"Sorting Nexin 10 as a Key Regulator of Membrane Trafficking in Bone-Resorbing Osteoclasts: Lessons Learned From Osteopetrosis",
Front Cell Dev Biol,
vol. 9,
pp. 671210,
2021.
DOI: | 10.3389/fcell.2021.671210 |
Datei: | https://www.ncbi.nlm.nih.gov/pubmed/34095139 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8173195/pdf/fcell-09-671210.pdf |
347.
T. Seibold,
J. Schönfelder,
F. Weeber,
A. Lechel,
M. Armacki,
M. Waldenmaier,
C. Wille,
A. Palmer,
R. Halbgebauer,
E. Karasu,
M. Huber-Lang,
M. Kalbitz,
P. Radermacher,
S. Paschke,
T. Seufferlein and
T. Eiseler,
"Small Extracellular Vesicles Propagate the Inflammatory Response After Trauma",
Adv Sci (Weinh),
vol. 8,
no. 24,
pp. e2102381,
2021.
DOI: | 10.1002/advs.202102381 |
Datei: | https://www.ncbi.nlm.nih.gov/pubmed/34713625 |
346.
A. E. P. Stratmann,
L. Wohlgemuth,
M. E. Erber,
S. Bernhard,
S. Hug,
M. Fauler,
L. Vidoni,
A. O. K. Mohamed,
B. D. Thomass,
F. Munnich,
L. Stukan,
K. J. Fohr,
M. Mannes,
M. S. Huber-Lang and
D. A. C. Messerer,
"Simultaneous Measurement of Changes in Neutrophil Granulocyte Membrane Potential, Intracellular pH, and Cell Size by Multiparametric Flow Cytometry",
Biomedicines,
vol. 9,
no. 11,
pp. 1504,
2021.
DOI: | 10.3390/biomedicines9111504 |
Datei: | https://www.ncbi.nlm.nih.gov/pubmed/34829733 https://mdpi-res.com/d_attachment/biomedicines/biomedicines-09-01504/article_deploy/biomedicines-09-01504-v4.pdf |
345.
K. Schuetze,
A. Eickhoff,
C. Dehner,
A. Blidon,
F. Gebhard and
P. H. Richter,
"Short-term outcome of fragility fractures of the pelvis in the elderly treated with screw osteosynthesis and external fixator",
Eur J Trauma Emerg Surg,
2021.
DOI: | 10.1007/s00068-021-01780-3 |
Datei: | https://www.ncbi.nlm.nih.gov/pubmed/34545420 |
344.
H. P. Muller,
D. Lule,
F. Roselli,
A. Behler,
A. C. Ludolph and
J. Kassubek,
"Segmental involvement of the corpus callosum in C9orf72-associated ALS: a tract of interest-based DTI study",
Ther Adv Chronic Dis,
vol. 12,
pp. 20406223211002969,
2021.
DOI: | 10.1177/20406223211002969 |
Datei: | https://www.ncbi.nlm.nih.gov/pubmed/33815737 https://journals.sagepub.com/doi/pdf/10.1177/20406223211002969 |
343.
S. Chakraborty,
V. E. Winkelmann,
S. Braumuller,
A. Palmer,
A. Schultze,
B. Klohs,
A. Ignatius,
A. Vater,
M. Fauler,
M. Frick and
M. Huber-Lang,
"Role of the C5a-C5a receptor axis in the inflammatory responses of the lungs after experimental polytrauma and hemorrhagic shock",
Sci Rep,
vol. 11,
no. 1,
pp. 2158,
2021.
DOI: | 10.1038/s41598-020-79607-1 |
Datei: | https://www.ncbi.nlm.nih.gov/pubmed/33495506 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7835219/pdf/41598_2020_Article_79607.pdf |
342.
C. Ehrnthaller,
A. Schultze,
G. Wakileh,
T. Neff,
S. Häfner,
P. Radermacher and
M. Huber-Lang,
"Hemorrhagic shock induces renal complement activation",
Eur J Trauma Emerg Surg,
vol. 47,
no. 2,
pp. 373-380,
2021.
DOI: | 10.1007/s00068-019-01187-1 |
Datei: | https://www.ncbi.nlm.nih.gov/pubmed/31309238 https://link.springer.com/content/pdf/10.1007/s00068-019-01187-1.pdf |
341.
E. Daini,
S. Hagmeyer,
C. A. De Benedictis,
J. S. Cristovao,
M. Bodria,
A. M. Ross,
A. Raab,
T. M. Boeckers,
J. Feldmann,
C. M. Gomes,
M. Zoli,
A. Vilella and
A. M. Grabrucker,
"S100B dysregulation during brain development affects synaptic SHANK protein networks via alteration of zinc homeostasis",
Translational Psychiatry,
vol. 11,
no. 1,
pp. 13,
2021.
DOI: | 10.1038/s41398-021-01694-z |
Datei: |
340.
T. Datzmann,
T. Merz,
O. McCook,
C. Szabo and
P. Radermacher,
"H2S as a Therapeutic Adjuvant Against COVID-19: Why and How?",
Shock,
vol. 56,
no. 5,
pp. 865-867,
2021.
DOI: | 10.1097/SHK.0000000000001723 |
Datei: | https://www.ncbi.nlm.nih.gov/pubmed/33443365 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8518209/pdf/shk-56-865.pdf |
339.
M. Barnea-Zohar,
S. E. Winograd-Katz,
M. Shalev,
E. Arman,
N. Reuven,
L. Roth,
O. Golani,
M. Stein,
F. Thalji,
M. Kanaan,
J. Tuckermann,
B. Geiger and
A. Elson,
"An SNX10-dependent mechanism downregulates fusion between mature osteoclasts",
J Cell Sci,
vol. 134,
no. 9,
pp. jcs254979,
2021.
2021 in press
338.
U. Stifel,
E. M. Wolfschmitt,
J. Vogt,
U. Wachter,
S. Vettorazzi,
D. Tews,
M. Hogg,
F. Zink,
N. M. Koll,
S. Winning,
R. Mounier,
B. Chazaud,
P. Radermacher,
P. Fischer-Posovszky,
G. Caratti and
J. Tuckermann,
"Glucocorticoids Coordinate Macrophage Metabolism Through Regulation of the Tricarboxylic Acid Cycle",
Mol Metab,
pp. 101424,
2021 in press.
DOI: | 10.1016/j.molmet.2021.101424 |
Datei: | https://www.ncbi.nlm.nih.gov/pubmed/34954109 |
2021
337.
C. Ehrnthaller,
S. Braumuller,
S. Kellermann,
F. Gebhard,
M. Perl and
M. Huber-Lang,
"Complement Factor C5a Inhibits Apoptosis of Neutrophils-A Mechanism in Polytrauma?",
J Clin Med,
vol. 10,
no. 14,
pp. 3157,
2021.
DOI: | 10.3390/jcm10143157 |
Datei: | https://www.ncbi.nlm.nih.gov/pubmed/34300323 https://mdpi-res.com/d_attachment/jcm/jcm-10-03157/article_deploy/jcm-10-03157-v2.pdf |
336.
M. Mannes,
C. Q. Schmidt,
B. Nilsson,
K. N. Ekdahl and
M. Huber-Lang,
"Complement as driver of systemic inflammation and organ failure in trauma, burn, and sepsis",
Semin Immunopathol,
vol. 43,
no. 6,
pp. 773-788,
2021.
DOI: | 10.1007/s00281-021-00872-x |
Datei: | https://www.ncbi.nlm.nih.gov/pubmed/34191093 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8243057/pdf/281_2021_Article_872.pdf |
335.
K. Ernst,
M. Landenberger,
J. Nieland,
K. Norgaard,
M. Frick,
G. Fois,
R. Benz and
H. Barth,
"Characterization and Pharmacological Inhibition of the Pore-Forming Clostridioides difficile CDTb Toxin",
Toxins (Basel),
vol. 13,
no. 6,
pp. 390,
2021.
DOI: | 10.3390/toxins13060390 |
Datei: | https://www.ncbi.nlm.nih.gov/pubmed/34071730 https://mdpi-res.com/d_attachment/toxins/toxins-13-00390/article_deploy/toxins-13-00390-v2.pdf |
334.
E. Kempter,
M. Amoroso,
H. L. Duffner,
A. M. Werner,
D. Langgartner,
S. Kupfer and
S. O. Reber,
"Changes in Functional Glucocorticoid Sensitivity of Isolated Splenocytes Induced by Chronic Psychosocial Stress - A Time Course Study",
Front Immunol,
vol. 12,
pp. 753822,
2021.
DOI: | 10.3389/fimmu.2021.753822 |
Datei: | https://www.ncbi.nlm.nih.gov/pubmed/34675935 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8523951/pdf/fimmu-12-753822.pdf |
333.
T. Merz,
O. McCook,
N. Denoix,
P. Radermacher,
C. Waller and
T. Kapapa,
"Biological Connection of Psychological Stress and Polytrauma under Intensive Care: The Role of Oxytocin and Hydrogen Sulfide",
Int J Mol Sci,
vol. 22,
no. 17,
pp. 9192,
2021.
DOI: | 10.3390/ijms22179192 |
Datei: | https://www.ncbi.nlm.nih.gov/pubmed/34502097 https://mdpi-res.com/d_attachment/ijms/ijms-22-09192/article_deploy/ijms-22-09192-v2.pdf |
332.
R. Rehman,
L. Tar,
A. J. Olamide,
Z. Li,
J. Kassubek,
T. Böckers,
J. Weishaupt,
A. Ludolph,
D. Wiesner and
F. Roselli,
"Acute TBK1/IKK-epsilon Inhibition Enhances the Generation of Disease-Associated Microglia-Like Phenotype Upon Cortical Stab-Wound Injury",
Front Aging Neurosci,
vol. 13,
pp. 684171,
2021.
DOI: | 10.3389/fnagi.2021.684171 |
Datei: | https://www.ncbi.nlm.nih.gov/pubmed/34326766 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8313992/pdf/fnagi-13-684171.pdf |
331.
M. Mannes,
A. Dopler,
O. Zolk,
S. J. Lang,
R. Halbgebauer,
B. Hochsmann,
A. Skerra,
C. K. Braun,
M. Huber-Lang,
H. Schrezenmeier and
C. Q. Schmidt,
"Complement inhibition at the level of C3 or C5: mechanistic reasons for ongoing terminal pathway activity",
Blood,
vol. 137,
no. 4,
pp. 443-455,
2021.
330.
S. Grabrucker,
J. Pagano,
J. Schweizer,
C. Urrutia-Ruiz,
M. Schon,
K. Thome,
G. Ehret,
A. M. Grabrucker,
R. Zhang,
B. Hengerer,
J. Bockmann,
C. Verpelli,
C. Sala and
T. M. Boeckers,
"Activation of the medial preoptic area (MPOA) ameliorates loss of maternal behavior in a Shank2 mouse model for autism",
Embo Journal,
vol. 40,
no. 5,
pp. 19,
2021.
DOI: | 10.15252/embj.2019104267 |
Datei: |
329.
S. Hug,
S. Bernhard,
A. E. P. Stratmann,
M. Erber,
L. Wohlgemuth,
C. L. Knapp,
J. M. Bauer,
L. Vidoni,
M. Fauler,
K. J. Fohr,
P. Radermacher,
A. Hoffmann,
M. Huber-Lang and
D. A. C. Messerer,
"Activation of Neutrophil Granulocytes by Platelet-Activating Factor Is Impaired During Experimental Sepsis",
Front Immunol,
vol. 12,
pp. 642867,
2021.
DOI: | 10.3389/fimmu.2021.642867 |
Datei: | https://www.ncbi.nlm.nih.gov/pubmed/33796110 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8007865/pdf/fimmu-12-642867.pdf |
328.
P. H. Richter,
A. Blidon,
A. Eickhoff,
F. Gebhard and
K. Schuetze,
"Accuracy of screw stabilization of the dorsal pelvic ring using a hybrid operating room: 5 Year experience in a level 1 trauma center",
Injury,
vol. 52,
no. 10,
pp. 2968-2972,
2021.
DOI: | 10.1016/j.injury.2021.06.024 |
Datei: | https://www.ncbi.nlm.nih.gov/pubmed/34275645 |
327.
S. Cursano,
C. R. Battaglia,
C. Urrutia-Ruiz,
S. Grabrucker,
M. Schon,
J. Bockmann,
S. Braumuller,
P. Radermacher,
F. Roselli,
M. Huber-Lang and
T. M. Boeckers,
"A CRHR1 antagonist prevents synaptic loss and memory deficits in a trauma-induced delirium-like syndrome",
Mol Psychiatry,
vol. 26,
no. 8,
pp. 3778-3794,
2021.
DOI: | 10.1038/s41380-020-0659-y |
Datei: | https://www.ncbi.nlm.nih.gov/pubmed/32051550 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8550963/pdf/41380_2020_Article_659.pdf |
326.
C. Leinert,
S. Brefka,
U. Braisch,
N. Denninger,
M. Mueller,
P. Benzinger,
J. Bauer,
A. Bahrmann,
N. Frey,
H. A. Katus,
T. Geisler,
G. Eschweiler,
J. Klaus,
T. Seufferlein,
K. Schuetze,
F. Gebhard,
J. Dreyhaupt,
R. Muche,
K. Pahmeier,
J. Biermann-Stallwitz,
J. Wasem,
L. Flagmeier,
D. Dallmeier and
M. Denkinger,
"A complex intervention to promote prevention of delirium in older adults by targeting caregiver's participation during and after hospital discharge - study protocol of the TRAnsport and DElirium in older people (TRADE) project",
BMC Geriatr,
vol. 21,
no. 1,
pp. 646,
2021.
DOI: | 10.1186/s12877-021-02585-0 |
Datei: | https://www.ncbi.nlm.nih.gov/pubmed/34784883 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8594294/pdf/12877_2021_Article_2585.pdf |
2021 accepted
325.
A. I. Mubashir Ahmad and
J. Tuckermann.,
" Inhibition of Cdk5 increases osteoblast differentiation and bone mass and improves fracture healing ",
Bone Research,
2021 accepted.
2021
324.
O. McCook,
N. Denoix,
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