Zusammenstellung von Bildern aus dem Sonderforschungsbereich


Z. Najafova, P. Liu, F. Wegwitz, M. Ahmad, L. Tamon, R. L. Kosinsky, W. Xie, S. A. Johnsen and J. Tuckermann, "RNF40 exerts stage-dependent functions in differentiating osteoblasts and is essential for bone cell crosstalk", Cell Death Differ, vol. 28, no. 2, pp. 700-714, 2021.
Datei:pdfhttps://www.ncbi.nlm.nih.gov/pubmed/32901120 https://www.nature.com/articles/s41418-020-00614-w.pdf
A. Elson, M. Stein, G. Rabie, M. Barnea-Zohar, S. Winograd-Katz, N. Reuven, M. Shalev, J. Sekeres, M. Kanaan, J. Tuckermann and B. Geiger, "Sorting Nexin 10 as a Key Regulator of Membrane Trafficking in Bone-Resorbing Osteoclasts: Lessons Learned From Osteopetrosis", Front Cell Dev Biol, vol. 9, pp. 671210, 2021.
Datei:pdfhttps://www.ncbi.nlm.nih.gov/pubmed/34095139 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8173195/pdf/fcell-09-671210.pdf
T. Seibold, J. Schönfelder, F. Weeber, A. Lechel, M. Armacki, M. Waldenmaier, C. Wille, A. Palmer, R. Halbgebauer, E. Karasu, M. Huber-Lang, M. Kalbitz, P. Radermacher, S. Paschke, T. Seufferlein and T. Eiseler, "Small Extracellular Vesicles Propagate the Inflammatory Response After Trauma", Adv Sci (Weinh), vol. 8, no. 24, pp. e2102381, 2021.
A. E. P. Stratmann, L. Wohlgemuth, M. E. Erber, S. Bernhard, S. Hug, M. Fauler, L. Vidoni, A. O. K. Mohamed, B. D. Thomass, F. Munnich, L. Stukan, K. J. Fohr, M. Mannes, M. S. Huber-Lang and D. A. C. Messerer, "Simultaneous Measurement of Changes in Neutrophil Granulocyte Membrane Potential, Intracellular pH, and Cell Size by Multiparametric Flow Cytometry", Biomedicines, vol. 9, no. 11, pp. 1504, 2021.
Datei:pdfhttps://www.ncbi.nlm.nih.gov/pubmed/34829733 https://mdpi-res.com/d_attachment/biomedicines/biomedicines-09-01504/article_deploy/biomedicines-09-01504-v4.pdf
K. Schuetze, A. Eickhoff, C. Dehner, A. Blidon, F. Gebhard and P. H. Richter, "Short-term outcome of fragility fractures of the pelvis in the elderly treated with screw osteosynthesis and external fixator", Eur J Trauma Emerg Surg, 2021.
H. P. Muller, D. Lule, F. Roselli, A. Behler, A. C. Ludolph and J. Kassubek, "Segmental involvement of the corpus callosum in C9orf72-associated ALS: a tract of interest-based DTI study", Ther Adv Chronic Dis, vol. 12, pp. 20406223211002969, 2021.
Datei:https://www.ncbi.nlm.nih.gov/pubmed/33815737 https://journals.sagepub.com/doi/pdf/10.1177/20406223211002969
E. Daini, S. Hagmeyer, C. A. De Benedictis, J. S. Cristovao, M. Bodria, A. M. Ross, A. Raab, T. M. Boeckers, J. Feldmann, C. M. Gomes, M. Zoli, A. Vilella and A. M. Grabrucker, "S100B dysregulation during brain development affects synaptic SHANK protein networks via alteration of zinc homeostasis", Translational Psychiatry, vol. 11, no. 1, pp. 13, 2021.
S. Chakraborty, V. E. Winkelmann, S. Braumuller, A. Palmer, A. Schultze, B. Klohs, A. Ignatius, A. Vater, M. Fauler, M. Frick and M. Huber-Lang, "Role of the C5a-C5a receptor axis in the inflammatory responses of the lungs after experimental polytrauma and hemorrhagic shock", Sci Rep, vol. 11, no. 1, pp. 2158, 2021.
Datei:pdfhttps://www.ncbi.nlm.nih.gov/pubmed/33495506 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7835219/pdf/41598_2020_Article_79607.pdf
C. Ehrnthaller, A. Schultze, G. Wakileh, T. Neff, S. Häfner, P. Radermacher and M. Huber-Lang, "Hemorrhagic shock induces renal complement activation", Eur J Trauma Emerg Surg, vol. 47, no. 2, pp. 373-380, 2021.
Datei:pdfhttps://www.ncbi.nlm.nih.gov/pubmed/31309238 https://link.springer.com/content/pdf/10.1007/s00068-019-01187-1.pdf
I. Lackner, B. Weber, M. Haffner-Luntzer, S. Hristova, F. Gebhard, C. Lam, K. Morioka, R. S. Marcucio, T. Miclau and M. Kalbitz, "Systemic and local cardiac inflammation after experimental long bone fracture, traumatic brain injury and combined trauma in mice", J Orthop Translat, vol. 28, pp. 39-46, 2021.
Datei:pdfhttps://www.ncbi.nlm.nih.gov/pubmed/33717980 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7906881/pdf/main.pdf
T. Datzmann, T. Merz, O. McCook, C. Szabo and P. Radermacher, "H2S as a Therapeutic Adjuvant Against COVID-19: Why and How?", Shock, vol. 56, no. 5, pp. 865-867, 2021.
Datei:pdfhttps://www.ncbi.nlm.nih.gov/pubmed/33443365 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8518209/pdf/shk-56-865.pdf
R. Rehman, L. Tar, A. J. Olamide, Z. Li, J. Kassubek, T. Böckers, J. Weishaupt, A. Ludolph, D. Wiesner and F. Roselli, "Acute TBK1/IKK-epsilon Inhibition Enhances the Generation of Disease-Associated Microglia-Like Phenotype Upon Cortical Stab-Wound Injury", Front Aging Neurosci, vol. 13, pp. 684171, 2021.
Datei:pdfhttps://www.ncbi.nlm.nih.gov/pubmed/34326766 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8313992/pdf/fnagi-13-684171.pdf
C. Ehrnthaller, S. Braumuller, S. Kellermann, F. Gebhard, M. Perl and M. Huber-Lang, "Complement Factor C5a Inhibits Apoptosis of Neutrophils-A Mechanism in Polytrauma?", J Clin Med, vol. 10, no. 14, pp. 3157, 2021.
Datei:pdfhttps://www.ncbi.nlm.nih.gov/pubmed/34300323 https://mdpi-res.com/d_attachment/jcm/jcm-10-03157/article_deploy/jcm-10-03157-v2.pdf
M. Mannes, C. Q. Schmidt, B. Nilsson, K. N. Ekdahl and M. Huber-Lang, "Complement as driver of systemic inflammation and organ failure in trauma, burn, and sepsis", Semin Immunopathol, vol. 43, no. 6, pp. 773-788, 2021.
Datei:pdfhttps://www.ncbi.nlm.nih.gov/pubmed/34191093 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8243057/pdf/281_2021_Article_872.pdf
K. Ernst, M. Landenberger, J. Nieland, K. Norgaard, M. Frick, G. Fois, R. Benz and H. Barth, "Characterization and Pharmacological Inhibition of the Pore-Forming Clostridioides difficile CDTb Toxin", Toxins (Basel), vol. 13, no. 6, pp. 390, 2021.
Datei:pdfhttps://www.ncbi.nlm.nih.gov/pubmed/34071730 https://mdpi-res.com/d_attachment/toxins/toxins-13-00390/article_deploy/toxins-13-00390-v2.pdf
E. Kempter, M. Amoroso, H. L. Duffner, A. M. Werner, D. Langgartner, S. Kupfer and S. O. Reber, "Changes in Functional Glucocorticoid Sensitivity of Isolated Splenocytes Induced by Chronic Psychosocial Stress - A Time Course Study", Front Immunol, vol. 12, pp. 753822, 2021.
Datei:pdfhttps://www.ncbi.nlm.nih.gov/pubmed/34675935 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8523951/pdf/fimmu-12-753822.pdf
T. Merz, O. McCook, N. Denoix, P. Radermacher, C. Waller and T. Kapapa, "Biological Connection of Psychological Stress and Polytrauma under Intensive Care: The Role of Oxytocin and Hydrogen Sulfide", Int J Mol Sci, vol. 22, no. 17, pp. 9192, 2021.
Datei:pdfhttps://www.ncbi.nlm.nih.gov/pubmed/34502097 https://mdpi-res.com/d_attachment/ijms/ijms-22-09192/article_deploy/ijms-22-09192-v2.pdf
K. Singh, P. Maity, A. K. Koroma, A. Basu, R. K. Pandey, S. Vander Beken, P. Haas, L. Krug, A. Hainzl, A. Sindrilaru, C. Pfeiffer, M. Wlaschek, N. Y. Frank, M. H. Frank, C. Ganss, A. Banvolgyi, N. Wikonkal, S. Eming, I. Pastar, M. Tomic-Canic, M. A. Kluth and K. Scharffetter-Kochanek, "Angiogenin Released from ABCB5(+) Stromal Precursors Improves Healing of Diabetic Wounds by Promoting Angiogenesis", J Invest Dermatol, 2021.
M. Barnea-Zohar, S. E. Winograd-Katz, M. Shalev, E. Arman, N. Reuven, L. Roth, O. Golani, M. Stein, F. Thalji, M. Kanaan, J. Tuckermann, B. Geiger and A. Elson, "An SNX10-dependent mechanism downregulates fusion between mature osteoclasts", J Cell Sci, vol. 134, no. 9, pp. jcs254979, 2021.
Datei:https://www.ncbi.nlm.nih.gov/pubmed/33975343 https://cob.silverchair-cdn.com/cob/content_public/journal/jcs/134/9/10.1242_jcs.254979/5/jcs254979.pdf?Expires=1643710970&Signature=rp4J8tPdKhrc--7Fhh6nMxcud-7hCNgjeUCrdGmqHeI2y7TstTzd6~L8DgR1daDRzS9dVAqrJIMy

2021 in press

U. Stifel, E. M. Wolfschmitt, J. Vogt, U. Wachter, S. Vettorazzi, D. Tews, M. Hogg, F. Zink, N. M. Koll, S. Winning, R. Mounier, B. Chazaud, P. Radermacher, P. Fischer-Posovszky, G. Caratti and J. Tuckermann, "Glucocorticoids Coordinate Macrophage Metabolism Through Regulation of the Tricarboxylic Acid Cycle", Mol Metab, pp. 101424, 2021 in press.


M. Mannes, A. Dopler, O. Zolk, S. J. Lang, R. Halbgebauer, B. Hochsmann, A. Skerra, C. K. Braun, M. Huber-Lang, H. Schrezenmeier and C. Q. Schmidt, "Complement inhibition at the level of C3 or C5: mechanistic reasons for ongoing terminal pathway activity", Blood, vol. 137, no. 4, pp. 443-455, 2021.
Datei:https://www.ncbi.nlm.nih.gov/pubmed/33507296 https://ashpublications.org/blood/article-abstract/137/4/443/474570/Complement-inhibition-at-the-level-of-C3-or-C5?redirectedFrom=fulltext
S. Grabrucker, J. Pagano, J. Schweizer, C. Urrutia-Ruiz, M. Schon, K. Thome, G. Ehret, A. M. Grabrucker, R. Zhang, B. Hengerer, J. Bockmann, C. Verpelli, C. Sala and T. M. Boeckers, "Activation of the medial preoptic area (MPOA) ameliorates loss of maternal behavior in a Shank2 mouse model for autism", Embo Journal, vol. 40, no. 5, pp. 19, 2021.
S. Hug, S. Bernhard, A. E. P. Stratmann, M. Erber, L. Wohlgemuth, C. L. Knapp, J. M. Bauer, L. Vidoni, M. Fauler, K. J. Fohr, P. Radermacher, A. Hoffmann, M. Huber-Lang and D. A. C. Messerer, "Activation of Neutrophil Granulocytes by Platelet-Activating Factor Is Impaired During Experimental Sepsis", Front Immunol, vol. 12, pp. 642867, 2021.
Datei:pdfhttps://www.ncbi.nlm.nih.gov/pubmed/33796110 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8007865/pdf/fimmu-12-642867.pdf
P. H. Richter, A. Blidon, A. Eickhoff, F. Gebhard and K. Schuetze, "Accuracy of screw stabilization of the dorsal pelvic ring using a hybrid operating room: 5 Year experience in a level 1 trauma center", Injury, vol. 52, no. 10, pp. 2968-2972, 2021.
S. Cursano, C. R. Battaglia, C. Urrutia-Ruiz, S. Grabrucker, M. Schon, J. Bockmann, S. Braumuller, P. Radermacher, F. Roselli, M. Huber-Lang and T. M. Boeckers, "A CRHR1 antagonist prevents synaptic loss and memory deficits in a trauma-induced delirium-like syndrome", Mol Psychiatry, vol. 26, no. 8, pp. 3778-3794, 2021.
Datei:pdfhttps://www.ncbi.nlm.nih.gov/pubmed/32051550 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8550963/pdf/41380_2020_Article_659.pdf