Zusammenstellung von Bildern aus dem Sonderforschungsbereich

2021

326.
C. Leinert, S. Brefka, U. Braisch, N. Denninger, M. Mueller, P. Benzinger, J. Bauer, A. Bahrmann, N. Frey, H. A. Katus, T. Geisler, G. Eschweiler, J. Klaus, T. Seufferlein, K. Schuetze, F. Gebhard, J. Dreyhaupt, R. Muche, K. Pahmeier, J. Biermann-Stallwitz, J. Wasem, L. Flagmeier, D. Dallmeier and M. Denkinger, "A complex intervention to promote prevention of delirium in older adults by targeting caregiver's participation during and after hospital discharge - study protocol of the TRAnsport and DElirium in older people (TRADE) project", BMC Geriatr, vol. 21, no. 1, pp. 646, 2021.
DOI:10.1186/s12877-021-02585-0
Datei:pdfhttps://www.ncbi.nlm.nih.gov/pubmed/34784883 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8594294/pdf/12877_2021_Article_2585.pdf

2021 accepted

325.
A. I. Mubashir Ahmad and J. Tuckermann., " Inhibition of Cdk5 increases osteoblast differentiation and bone mass and improves fracture healing ", Bone Research, 2021 accepted.

2021

324.
O. McCook, N. Denoix, P. Radermacher, C. Waller and T. Merz, "H2S and Oxytocin Systems in Early Life Stress and Cardiovascular Disease", J Clin Med, vol. 10, no. 16, pp. 3484, 2021.
DOI:10.3390/jcm10163484
Datei:pdfhttps://www.ncbi.nlm.nih.gov/pubmed/34441780 https://mdpi-res.com/d_attachment/jcm/jcm-10-03484/article_deploy/jcm-10-03484-v2.pdf
323.
M. S. Huber-Lang, A. Ignatius, J. Kohl, M. Mannes and C. K. Braun, "Complement in Trauma - Traumatised Complement?", Br J Pharmacol, vol. 178, no. 14, pp. 2863-2879, 2021.
DOI:10.1111/bph.15245
Datei:https://www.ncbi.nlm.nih.gov/pubmed/32880897
322.
S. Vettorazzi, D. Nalbantoglu, J. C. M. Gebhardt and J. Tuckermann, "A guide to changing paradigms of glucocorticoid receptor function-a model system for genome regulation and physiology", FEBS J, 2021.
DOI:10.1111/febs.16100
Datei:https://www.ncbi.nlm.nih.gov/pubmed/34213830
321.
J. Scekic-Zahirovic, I. Sanjuan-Ruiz, V. Kan, S. Megat, P. De Rossi, S. Dieterle, R. Cassel, M. Jamet, P. Kessler, D. Wiesner, L. Tzeplaeff, V. Demais, S. Sahadevan, K. M. Hembach, H. P. Muller, G. Picchiarelli, N. Mishra, S. Antonucci, S. Dirrig-Grosch, J. Kassubek, V. Rasche, A. Ludolph, A. L. Boutillier, F. Roselli, M. Polymenidou, C. Lagier-Tourenne, S. Liebscher and L. Dupuis, "Cytoplasmic FUS triggers early behavioral alterations linked to cortical neuronal hyperactivity and inhibitory synaptic defects", Nat Commun, vol. 12, no. 1, pp. 3028, 2021.
DOI:10.1038/s41467-021-23187-9
Datei:pdfhttps://www.ncbi.nlm.nih.gov/pubmed/34021132 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8140148/pdf/41467_2021_Article_23187.pdf
320.
B. Weber, I. Lackner, M. Baur, F. Gebhard, R. Pfeifer, P. Cinelli, S. Halvachizadeh, M. Teuben, H. C. Pape, A. Imhof, M. Lipiski, N. Cesarovic and M. Kalbitz, "Early myocardial damage (EMD) and valvular insufficiency result in impaired cardiac function after multiple trauma in pigs", Sci Rep, vol. 11, no. 1, pp. 1151, 2021.
DOI:10.1038/s41598-020-80409-8
Datei:pdfhttps://www.ncbi.nlm.nih.gov/pubmed/33441945 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7806767/pdf/41598_2020_Article_80409.pdf
319.
M. Singer, P. J. Young, J. G. Laffey, P. Asfar, F. S. Taccone, M. B. Skrifvars, C. S. Meyhoff and P. Radermacher, "Dangers of hyperoxia", Crit Care, vol. 25, no. 1, pp. 440, 2021.
DOI:10.1186/s13054-021-03815-y
Datei:https://www.ncbi.nlm.nih.gov/pubmed/34924022
318.
M. Haffner-Luntzer, "Experimental agents to improve fracture healing: utilizing the WNT signaling pathway", Injury, vol. 52, pp. S44-S48, 2021.
DOI:10.1016/j.injury.2020.11.051
Datei:http://www.sciencedirect.com/science/article/pii/S0020138320309773
317.
A. Kerstan, E. Niebergall-Roth, J. Esterlechner, H. M. Schroder, M. Gasser, A. M. Waaga-Gasser, M. Goebeler, K. Rak, P. Schrufer, S. Endres, P. Hagenbusch, K. Kraft, K. Dieter, S. Ballikaya, N. Stemler, S. Sadeghi, N. Tappenbeck, G. F. Murphy, D. P. Orgill, N. Y. Frank, C. Ganss, K. Scharffetter-Kochanek, M. H. Frank and M. A. Kluth, "Ex vivo-expanded highly pure ABCB5(+) mesenchymal stromal cells as Good Manufacturing Practice-compliant autologous advanced therapy medicinal product for clinical use: process validation and first in-human data", Cytotherapy, vol. 23, no. 2, pp. 165-175, 2021.
DOI:10.1016/j.jcyt.2020.08.012
Datei:pdfhttps://www.ncbi.nlm.nih.gov/pubmed/33011075 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8310651/pdf/nihms-1714686.pdf
316.
S. A. Appiah, C. L. Foxx, D. Langgartner, A. Palmer, C. A. Zambrano, S. Braumuller, E. J. Schaefer, U. Wachter, B. L. Elam, P. Radermacher, C. E. Stamper, J. D. Heinze, S. N. Salazar, A. K. Luthens, A. L. Arnold, S. O. Reber, M. Huber-Lang, C. A. Lowry and R. Halbgebauer, "Evaluation of the gut microbiome in association with biological signatures of inflammation in murine polytrauma and shock", Sci Rep, vol. 11, no. 1, pp. 6665, 2021.
DOI:10.1038/s41598-021-85897-w
Datei:pdfhttps://www.ncbi.nlm.nih.gov/pubmed/33758228 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7988149/pdf/41598_2021_Article_85897.pdf
315.
S. Ehnert, B. Relja, K. Schmidt-Bleek, V. Fischer, A. Ignatius, C. Linnemann, H. Rinderknecht, M. Huber-Lang, M. Kalbitz, T. Histing and A. Nüssler, "Effects of immune cells on mesenchymal stem cells during fracture healing", World J Stem Cells, vol. 13, no. 11, pp. 1667-1695, 2021.
DOI:DOI: 10.4252/wjsc.v13.i11.1667
314.
F. Zink, J. Vogt, U. Wachter, J. Hartert, M. Horchler, X. Zhang, F. Hezel, T. Kapapa, T. Datzmann, A. Hoffmann, M. Wepler, E. Calzia, P. Radermacher and C. Hartmann, "Effects of Acute Subdural Hematoma-Induced Brain Injury On Energy Metabolism in Peripheral Blood Mononuclear Cells", Shock, vol. 55, no. 3, pp. 407-417, 2021.
DOI:10.1097/SHK.0000000000001642
Datei:https://www.ncbi.nlm.nih.gov/pubmed/32826816
313.
R. Cintean, C. Pankratz, M. Hofmann, F. Gebhard and K. Schutze, "Early Results in Non-Displaced Femoral Neck Fractures Using the Femoral Neck System", Geriatr Orthop Surg Rehabil, vol. 12, pp. 21514593211050153, 2021.
DOI:10.1177/21514593211050153
Datei:https://www.ncbi.nlm.nih.gov/pubmed/34733579 https://journals.sagepub.com/doi/pdf/10.1177/21514593211050153
312.
S. Preau, D. Vodovar, B. Jung, S. Lancel, L. Zafrani, A. Flatres, M. Oualha, G. Voiriot, Y. Jouan, J. Joffre, F. Huel, N. De Prost, S. Silva, E. Azabou and P. Radermacher, "Energetic dysfunction in sepsis: a narrative review", Ann Intensive Care, vol. 11, no. 1, pp. 104, 2021.
DOI:10.1186/s13613-021-00893-7
Datei:pdfhttps://www.ncbi.nlm.nih.gov/pubmed/34216304 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8254847/pdf/13613_2021_Article_893.pdf
311.
B. Weber, I. Lackner, T. Miclau, J. Stulz, F. Gebhard, R. Pfeifer, P. Cinelli, S. Halvachizadeh, M. Teuben, H. C. Pape, M. Lipiski, N. Cesarovic and M. Kalbitz, "Early myocardial damage (EMD) and valvular dysfunction after femur fracture in pigs", Sci Rep, vol. 11, no. 1, pp. 8503, 2021.
DOI:10.1038/s41598-021-86151-z
Datei:pdfhttps://www.ncbi.nlm.nih.gov/pubmed/33875675 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8055677/pdf/41598_2021_Article_86151.pdf
310.
B. Trautwein, T. Merz, N. Denoix, C. Szabo, E. Calzia, P. Radermacher and O. McCook, "DeltaMST and the Regulation of Cardiac CSE and OTR Expression in Trauma and Hemorrhage", Antioxidants (Basel), vol. 10, no. 2, pp. 233, 2021.
DOI:10.3390/antiox10020233
Datei:pdfhttps://www.ncbi.nlm.nih.gov/pubmed/33546491 https://mdpi-res.com/d_attachment/antioxidants/antioxidants-10-00233/article_deploy/antioxidants-10-00233-v2.pdf
309.
D. Bayer, S. Antonucci, H. P. Muller, R. Saad, L. Dupuis, V. Rasche, T. M. Böckers, A. C. Ludolph, J. Kassubek and F. Roselli, "Disruption of orbitofrontal-hypothalamic projections in a murine ALS model and in human patients", Transl Neurodegener, vol. 10, no. 1, pp. 17, 2021.
DOI:10.1186/s40035-021-00241-6
Datei:pdfhttps://www.ncbi.nlm.nih.gov/pubmed/34059131 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8168014/pdf/40035_2021_Article_241.pdf
308.
Z. Li, J. Zhang, S. Halbgebauer, A. Chandrasekar, R. Rehman, A. Ludolph, T. Boeckers, M. Huber-Lang, M. Otto, F. Roselli and F. O. Heuvel, "Differential effect of ethanol intoxication on peripheral markers of cerebral injury in murine blunt traumatic brain injury", Burns Trauma, vol. 9, pp. tkab027, 2021.
DOI:10.1093/burnst/tkab027
Datei:pdfhttps://www.ncbi.nlm.nih.gov/pubmed/34604393 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8484207/pdf/tkab027.pdf
307.
M. Haffner-Luntzer, V. Fischer and A. Ignatius, "Differences in Fracture Healing Between Female and Male C57BL/6J Mice", Front Physiol, vol. 12, pp. 1227, 2021.
DOI:10.3389/fphys.2021.712494
Datei:https://www.frontiersin.org/article/10.3389/fphys.2021.712494
306.
A. Mossa, J. Pagano, L. Ponzoni, A. Tozzi, E. Vezzoli, M. Sciaccaluga, C. Costa, S. Beretta, M. Francolini, M. Sala, P. Calabresi, T. M. Boeckers, C. Sala and C. Verpelli, "Developmental impaired Akt signaling in the Shank1 and Shank3 double knock-out mice", Molecular Psychiatry, vol. 26, pp. 1928–1944, 2021.
DOI:10.1038/s41380-020-00979-x
Datei:pdf
305.
D. A. C. Messerer, M. Fauler, A. Horneffer, A. Schneider, O. Keis, L. M. Mauder and P. Radermacher, "Do medical students recognise the deteriorating patient by analysing their vital signs? A monocentric observational study based on the National Early Warning Score 2", BMJ Open, vol. 11, no. 2, pp. e044354, 2021.
DOI:10.1136/bmjopen-2020-044354
Datei:https://www.ncbi.nlm.nih.gov/pubmed/33622952
304.
P. Pfänder, A. K. Eiers, U. Burret and S. Vettorazzi, "Deletion of Cdk5 in Macrophages Ameliorates Anti-Inflammatory Response during Endotoxemia through Induction of C-Maf and Il-10", Int J Mol Sci, vol. 22, no. 17, pp. 9648, 2021.
DOI:10.3390/ijms22179648
Datei:pdfhttps://www.ncbi.nlm.nih.gov/pubmed/34502552 https://mdpi-res.com/d_attachment/ijms/ijms-22-09648/article_deploy/ijms-22-09648-v2.pdf

2020

303.
D. Jiang, K. Singh, J. Muschhammer, S. Schatz, A. Sindrilaru, E. Makrantonaki, Y. Qi, M. Wlaschek and K. Scharffetter-Kochanek, "MSCs rescue impaired wound healing in a murine LAD1 model by adaptive responses to low TGF-beta1 levels", EMBO Rep, vol. 21, no. 4, pp. e49115, 2020.
DOI:10.15252/embr.201949115
Datei:pdfhttps://www.ncbi.nlm.nih.gov/pubmed/32080965 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7132342/pdf/EMBR-21-e49115.pdf
302.
C. Schopper, M. Faschingbauer, R. T. Moeller, F. Gebhard, L. Duerselen and A. Seitz, "Modified Candy-Package technique vs Cerclage technique for refixation of the lesser trochanteric fragment in pertrochanteric femoral fractures. A biomechanical comparison of 10 specimens", Injury, vol. 51, no. 8, pp. 1763-1768, 2020.
DOI:10.1016/j.injury.2020.06.008
Datei:https://www.ncbi.nlm.nih.gov/pubmed/32580889