Zusammenstellung von Bildern aus dem Sonderforschungsbereich


C. Leinert, S. Brefka, U. Braisch, N. Denninger, M. Mueller, P. Benzinger, J. Bauer, A. Bahrmann, N. Frey, H. A. Katus, T. Geisler, G. Eschweiler, J. Klaus, T. Seufferlein, K. Schuetze, F. Gebhard, J. Dreyhaupt, R. Muche, K. Pahmeier, J. Biermann-Stallwitz, J. Wasem, L. Flagmeier, D. Dallmeier and M. Denkinger, "A complex intervention to promote prevention of delirium in older adults by targeting caregiver's participation during and after hospital discharge - study protocol of the TRAnsport and DElirium in older people (TRADE) project", BMC Geriatr, vol. 21, no. 1, pp. 646, 2021.
Datei:pdfhttps://www.ncbi.nlm.nih.gov/pubmed/34784883 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8594294/pdf/12877_2021_Article_2585.pdf

2021 accepted

A. I. Mubashir Ahmad and J. Tuckermann., " Inhibition of Cdk5 increases osteoblast differentiation and bone mass and improves fracture healing ", Bone Research, 2021 accepted.


O. McCook, N. Denoix, P. Radermacher, C. Waller and T. Merz, "H2S and Oxytocin Systems in Early Life Stress and Cardiovascular Disease", J Clin Med, vol. 10, no. 16, pp. 3484, 2021.
Datei:pdfhttps://www.ncbi.nlm.nih.gov/pubmed/34441780 https://mdpi-res.com/d_attachment/jcm/jcm-10-03484/article_deploy/jcm-10-03484-v2.pdf
M. S. Huber-Lang, A. Ignatius, J. Kohl, M. Mannes and C. K. Braun, "Complement in Trauma - Traumatised Complement?", Br J Pharmacol, vol. 178, no. 14, pp. 2863-2879, 2021.
S. Vettorazzi, D. Nalbantoglu, J. C. M. Gebhardt and J. Tuckermann, "A guide to changing paradigms of glucocorticoid receptor function-a model system for genome regulation and physiology", FEBS J, 2021.
J. Scekic-Zahirovic, I. Sanjuan-Ruiz, V. Kan, S. Megat, P. De Rossi, S. Dieterle, R. Cassel, M. Jamet, P. Kessler, D. Wiesner, L. Tzeplaeff, V. Demais, S. Sahadevan, K. M. Hembach, H. P. Muller, G. Picchiarelli, N. Mishra, S. Antonucci, S. Dirrig-Grosch, J. Kassubek, V. Rasche, A. Ludolph, A. L. Boutillier, F. Roselli, M. Polymenidou, C. Lagier-Tourenne, S. Liebscher and L. Dupuis, "Cytoplasmic FUS triggers early behavioral alterations linked to cortical neuronal hyperactivity and inhibitory synaptic defects", Nat Commun, vol. 12, no. 1, pp. 3028, 2021.
Datei:pdfhttps://www.ncbi.nlm.nih.gov/pubmed/34021132 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8140148/pdf/41467_2021_Article_23187.pdf
B. Weber, I. Lackner, M. Baur, F. Gebhard, R. Pfeifer, P. Cinelli, S. Halvachizadeh, M. Teuben, H. C. Pape, A. Imhof, M. Lipiski, N. Cesarovic and M. Kalbitz, "Early myocardial damage (EMD) and valvular insufficiency result in impaired cardiac function after multiple trauma in pigs", Sci Rep, vol. 11, no. 1, pp. 1151, 2021.
Datei:pdfhttps://www.ncbi.nlm.nih.gov/pubmed/33441945 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7806767/pdf/41598_2020_Article_80409.pdf
M. Singer, P. J. Young, J. G. Laffey, P. Asfar, F. S. Taccone, M. B. Skrifvars, C. S. Meyhoff and P. Radermacher, "Dangers of hyperoxia", Crit Care, vol. 25, no. 1, pp. 440, 2021.
M. Haffner-Luntzer, "Experimental agents to improve fracture healing: utilizing the WNT signaling pathway", Injury, vol. 52, pp. S44-S48, 2021.
A. Kerstan, E. Niebergall-Roth, J. Esterlechner, H. M. Schroder, M. Gasser, A. M. Waaga-Gasser, M. Goebeler, K. Rak, P. Schrufer, S. Endres, P. Hagenbusch, K. Kraft, K. Dieter, S. Ballikaya, N. Stemler, S. Sadeghi, N. Tappenbeck, G. F. Murphy, D. P. Orgill, N. Y. Frank, C. Ganss, K. Scharffetter-Kochanek, M. H. Frank and M. A. Kluth, "Ex vivo-expanded highly pure ABCB5(+) mesenchymal stromal cells as Good Manufacturing Practice-compliant autologous advanced therapy medicinal product for clinical use: process validation and first in-human data", Cytotherapy, vol. 23, no. 2, pp. 165-175, 2021.
Datei:pdfhttps://www.ncbi.nlm.nih.gov/pubmed/33011075 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8310651/pdf/nihms-1714686.pdf
S. A. Appiah, C. L. Foxx, D. Langgartner, A. Palmer, C. A. Zambrano, S. Braumuller, E. J. Schaefer, U. Wachter, B. L. Elam, P. Radermacher, C. E. Stamper, J. D. Heinze, S. N. Salazar, A. K. Luthens, A. L. Arnold, S. O. Reber, M. Huber-Lang, C. A. Lowry and R. Halbgebauer, "Evaluation of the gut microbiome in association with biological signatures of inflammation in murine polytrauma and shock", Sci Rep, vol. 11, no. 1, pp. 6665, 2021.
Datei:pdfhttps://www.ncbi.nlm.nih.gov/pubmed/33758228 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7988149/pdf/41598_2021_Article_85897.pdf
S. Ehnert, B. Relja, K. Schmidt-Bleek, V. Fischer, A. Ignatius, C. Linnemann, H. Rinderknecht, M. Huber-Lang, M. Kalbitz, T. Histing and A. Nüssler, "Effects of immune cells on mesenchymal stem cells during fracture healing", World J Stem Cells, vol. 13, no. 11, pp. 1667-1695, 2021.
DOI:DOI: 10.4252/wjsc.v13.i11.1667
F. Zink, J. Vogt, U. Wachter, J. Hartert, M. Horchler, X. Zhang, F. Hezel, T. Kapapa, T. Datzmann, A. Hoffmann, M. Wepler, E. Calzia, P. Radermacher and C. Hartmann, "Effects of Acute Subdural Hematoma-Induced Brain Injury On Energy Metabolism in Peripheral Blood Mononuclear Cells", Shock, vol. 55, no. 3, pp. 407-417, 2021.
R. Cintean, C. Pankratz, M. Hofmann, F. Gebhard and K. Schutze, "Early Results in Non-Displaced Femoral Neck Fractures Using the Femoral Neck System", Geriatr Orthop Surg Rehabil, vol. 12, pp. 21514593211050153, 2021.
Datei:https://www.ncbi.nlm.nih.gov/pubmed/34733579 https://journals.sagepub.com/doi/pdf/10.1177/21514593211050153
S. Preau, D. Vodovar, B. Jung, S. Lancel, L. Zafrani, A. Flatres, M. Oualha, G. Voiriot, Y. Jouan, J. Joffre, F. Huel, N. De Prost, S. Silva, E. Azabou and P. Radermacher, "Energetic dysfunction in sepsis: a narrative review", Ann Intensive Care, vol. 11, no. 1, pp. 104, 2021.
Datei:pdfhttps://www.ncbi.nlm.nih.gov/pubmed/34216304 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8254847/pdf/13613_2021_Article_893.pdf
B. Weber, I. Lackner, T. Miclau, J. Stulz, F. Gebhard, R. Pfeifer, P. Cinelli, S. Halvachizadeh, M. Teuben, H. C. Pape, M. Lipiski, N. Cesarovic and M. Kalbitz, "Early myocardial damage (EMD) and valvular dysfunction after femur fracture in pigs", Sci Rep, vol. 11, no. 1, pp. 8503, 2021.
Datei:pdfhttps://www.ncbi.nlm.nih.gov/pubmed/33875675 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8055677/pdf/41598_2021_Article_86151.pdf
B. Trautwein, T. Merz, N. Denoix, C. Szabo, E. Calzia, P. Radermacher and O. McCook, "DeltaMST and the Regulation of Cardiac CSE and OTR Expression in Trauma and Hemorrhage", Antioxidants (Basel), vol. 10, no. 2, pp. 233, 2021.
Datei:pdfhttps://www.ncbi.nlm.nih.gov/pubmed/33546491 https://mdpi-res.com/d_attachment/antioxidants/antioxidants-10-00233/article_deploy/antioxidants-10-00233-v2.pdf
D. Bayer, S. Antonucci, H. P. Muller, R. Saad, L. Dupuis, V. Rasche, T. M. Böckers, A. C. Ludolph, J. Kassubek and F. Roselli, "Disruption of orbitofrontal-hypothalamic projections in a murine ALS model and in human patients", Transl Neurodegener, vol. 10, no. 1, pp. 17, 2021.
Datei:pdfhttps://www.ncbi.nlm.nih.gov/pubmed/34059131 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8168014/pdf/40035_2021_Article_241.pdf
Z. Li, J. Zhang, S. Halbgebauer, A. Chandrasekar, R. Rehman, A. Ludolph, T. Boeckers, M. Huber-Lang, M. Otto, F. Roselli and F. O. Heuvel, "Differential effect of ethanol intoxication on peripheral markers of cerebral injury in murine blunt traumatic brain injury", Burns Trauma, vol. 9, pp. tkab027, 2021.
Datei:pdfhttps://www.ncbi.nlm.nih.gov/pubmed/34604393 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8484207/pdf/tkab027.pdf
M. Haffner-Luntzer, V. Fischer and A. Ignatius, "Differences in Fracture Healing Between Female and Male C57BL/6J Mice", Front Physiol, vol. 12, pp. 1227, 2021.
A. Mossa, J. Pagano, L. Ponzoni, A. Tozzi, E. Vezzoli, M. Sciaccaluga, C. Costa, S. Beretta, M. Francolini, M. Sala, P. Calabresi, T. M. Boeckers, C. Sala and C. Verpelli, "Developmental impaired Akt signaling in the Shank1 and Shank3 double knock-out mice", Molecular Psychiatry, vol. 26, pp. 1928–1944, 2021.
D. A. C. Messerer, M. Fauler, A. Horneffer, A. Schneider, O. Keis, L. M. Mauder and P. Radermacher, "Do medical students recognise the deteriorating patient by analysing their vital signs? A monocentric observational study based on the National Early Warning Score 2", BMJ Open, vol. 11, no. 2, pp. e044354, 2021.
P. Pfänder, A. K. Eiers, U. Burret and S. Vettorazzi, "Deletion of Cdk5 in Macrophages Ameliorates Anti-Inflammatory Response during Endotoxemia through Induction of C-Maf and Il-10", Int J Mol Sci, vol. 22, no. 17, pp. 9648, 2021.
Datei:pdfhttps://www.ncbi.nlm.nih.gov/pubmed/34502552 https://mdpi-res.com/d_attachment/ijms/ijms-22-09648/article_deploy/ijms-22-09648-v2.pdf


D. Jiang, K. Singh, J. Muschhammer, S. Schatz, A. Sindrilaru, E. Makrantonaki, Y. Qi, M. Wlaschek and K. Scharffetter-Kochanek, "MSCs rescue impaired wound healing in a murine LAD1 model by adaptive responses to low TGF-beta1 levels", EMBO Rep, vol. 21, no. 4, pp. e49115, 2020.
Datei:pdfhttps://www.ncbi.nlm.nih.gov/pubmed/32080965 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7132342/pdf/EMBR-21-e49115.pdf
C. Schopper, M. Faschingbauer, R. T. Moeller, F. Gebhard, L. Duerselen and A. Seitz, "Modified Candy-Package technique vs Cerclage technique for refixation of the lesser trochanteric fragment in pertrochanteric femoral fractures. A biomechanical comparison of 10 specimens", Injury, vol. 51, no. 8, pp. 1763-1768, 2020.