Zusammenstellung von Bildern aus dem Sonderforschungsbereich

Publikationen aus dem SFB 1149

2019

219.
B. Weber, I. Lackner, M. Haffner-Luntzer, A. Palmer, J. Pressmar, K. Scharffetter-Kochanek, B. Knöll, H. Schrezenmeier, B. Relja and M. Kalbitz, "Modeling trauma in rats: similarities to humans and potential pitfalls to consider", J Transl Med, vol. 17, no. 1, pp. 305, 2019.
DOI:10.1186/s12967-019-2052-7
Datei:https://doi.org/10.1186/s12967-019-2052-7
218.
S. Vander Beken, J. C. Vries, B. Meier-Schiesser, P. Meyer, D. Jiang, A. Sindrilaru, F. F. Ferreira, A. Hainzl, S. Schatz, J. Muschhammer, N. J. Scheurmann, P. Kampilafkos, A. M. Seitz, L. Dürselen, M. A. Kluth, C. Ganss, M. Wlaschek, K. Singh, P. Maity, N. Y. Frank, M. H. Frank and K. Scharffetter-Kochanek, "Newly defined ABCB5(+) dermal mesenchymal stem cells promote healing of chronic iron overload wounds via secretion of interleukin-1 receptor antagonist", Stem Cells, vol. 37, no. 8, pp. 1057-1074, 2019.
DOI:10.1002/stem.3022
Datei:https://www.ncbi.nlm.nih.gov/pubmed/31002437
217.
K. Schuetze, A. Eickhoff, G. Röderer, F. Gebhard and P. H. Richter, "Osteoporotic Bone: When and How to Use Augmentation?", J Orthop Trauma, vol. 33 Suppl 8, pp. S21-S26, 2019.
DOI:10.1097/BOT.0000000000001643
Datei:https://www.ncbi.nlm.nih.gov/pubmed/31688523
216.
J. Hellman, S. Bahrami, I. H. Chaudry, G. Fritsch, W. Gozdzik, S. Inoue, P. Radermacher, M. Singer and M. F. Osuchowski, "Part III: Minimum Quality Threshold in Preclinical Sepsis Studies (MQTiPSS) for Fluid Resuscitation and Antimicrobial Therapy Endpoints", Shock, vol. 51, no. 1, pp. 33-43, 2019.
DOI:10.1097/SHK.0000000000001209
Datei:https://www.ncbi.nlm.nih.gov/pubmed/29923896
215.
A. Chandrasekar, F. O. Heuvel, L. Tar, A. M. Hagenston, A. Palmer, B. Linkus, A. C. Ludolph, T. Boeckers, H. Bading and F. Roselli, "Parvalbumin Interneurons Shape Neuronal Vulnerability in Blunt TBI", Cereb Cortex, vol. 29, no. 6, pp. 2701-2715, 2019.
DOI:10.1093/cercor/bhy139
Datei:https://www.ncbi.nlm.nih.gov/pubmed/29982364 https://watermark.silverchair.com/bhy139.pdf?token=AQECAHi208BE49Ooan9kkhW_Ercy7Dm3ZL_9Cf3qfKAc485ysgAAAuIwggLeBgkqhkiG9w0BBwagggLPMIICywIBADCCAsQGCSqGSIb3DQEHATAeBglghkgBZQMEAS4wEQQMkYeSXmWjjC7a_ciTAgEQgIIClV
214.
A. Guillon, S. Preau, J. Aboab, E. Azabou, B. Jung, S. Silva, J. Textoris, F. Uhel, D. Vodovar, L. Zafrani, N. Prost, P. Radermacher and S. French Intensive Care, "Preclinical septic shock research: why we need an animal ICU", Ann Intensive Care, vol. 9, no. 1, pp. 66, 2019.
DOI:10.1186/s13613-019-0543-6
Datei:https://www.ncbi.nlm.nih.gov/pubmed/31183570 https://hal.archives-ouvertes.fr/hal-02153561/document
213.
A. E. Rapp, A. Vikman, Z. Ren, V. Fischer, S. Bergdolt, W. C. Song, J. D. Lambris, C. Neidlinger-Wilke and R. Brenner, "Reduced Terminal Complement Complex Formation in Mice Manifests in Low Bone Mass and Impaired Fracture Healing", Am J Pathol, vol. 189, no. 1, pp. 147-161, 2019.
DOI:10.1016/j.ajpath.2018.09.011
Datei:https://www.ncbi.nlm.nih.gov/pubmed/30339839
212.
L. Wrba, J. J. Ohmann, P. Eisele, S. Chakraborty, S. Braumuller, C. K. Braun, B. Klohs, A. Schultze, H. Baum and A. Palmer, "Remote Intestinal Injury Early After Experimental Polytrauma and Hemorrhagic Shock", Shock, vol. 52, no. 4, pp. e45-e51, 2019.
DOI:10.1097/SHK.0000000000001271
Datei:https://www.ncbi.nlm.nih.gov/pubmed/30289852
211.
A. Catanese, F. Olde Heuvel, M. Mulaw, M. Demestre, J. Higelin, G. Barbi, A. Freischmidt, J. H. Weishaupt, A. C. Ludolph, F. Roselli and T. M. Boeckers, "Retinoic acid worsens ATG10-dependent autophagy impairment in TBK1-mutant hiPSC-derived motoneurons through SQSTM1/p62 accumulation", Autophagy, vol. 15, no. 10, pp. 1719-1737, 2019.
DOI:10.1080/15548627.2019.1589257
Datei:pdfhttps://www.ncbi.nlm.nih.gov/pubmed/30939964 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6735587/pdf/kaup-15-10-1589257.pdf
210.
S. Foertsch, B. Weber, A. M. Fuchsl, E. Wirkert, S. Peters, G. Fois, J. Pressmar, J. M. Fegert, M. Frick, H. Gundel, M. Kalbitz and S. O. Reber, "Sensory contact to the stressor prevents recovery from structural and functional heart damage following psychosocial trauma", Brain Behav Immun, vol. 80, pp. 667-677, 2019.
DOI:10.1016/j.bbi.2019.05.013
Datei:https://www.ncbi.nlm.nih.gov/pubmed/31085218
209.
C. Schilling, T. Mack, S. Lickfett, S. Sieste, F. S. Ruggeri, T. Sneideris, A. Dutta, T. Bereau, R. Naraghi, D. Sinske, T. P. J. Knowles, C. V. Synatschke, T. Weil and B. Knöll, "Sequence-Optimized Peptide Nanofibers as Growth Stimulators for Regeneration of Peripheral Neurons", Advanced Functional Materials, vol. 29, no. 24, pp. 1809112, 2019.
DOI:https://doi.org/10.1002/adfm.201809112
Datei:
208.
H. Honkoop, D. E. Bakker, A. Aharonov, F. Kruse, A. Shakked, P. D. Nguyen, C. Heus, L. Garric, M. J. Muraro, A. Shoffner, F. Tessadori, J. C. Peterson, W. Noort, A. Bertozzi, G. Posthuma, D. Grun, W. J. Laarse, J. Klumperman, R. T. Jaspers, K. D. Poss, A. Oudenaarden, E. Tzahor and J. Bakkers, "Single-cell analysis uncovers that metabolic reprogramming by ErbB2 signaling is essential for cardiomyocyte proliferation in the regenerating heart", Elife, vol. 8, 2019.
DOI:10.7554/eLife.50163
Datei:pdfhttps://www.ncbi.nlm.nih.gov/pubmed/31868166 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7000220/pdf/elife-50163.pdf
207.
F. Olde Heuvel, S. Holl, A. Chandrasekar, Z. Li, R. Rehman, P. Forstner, D. Sinske, A. Palmer, D. Wiesner, A. Ludolph, B. Relja, T. Wirth, T. Boeckers, B. Knöll and F. Roselli, "STAT6 mediates the effect of ethanol on neuroinflammatory response in TBI", Brain Behav Immun, vol. 81, pp. 228-246, 2019.
DOI:10.1016/j.bbi.2019.06.019
Datei:https://www.ncbi.nlm.nih.gov/pubmed/31207335
206.
A. J. Heck, T. Ostertag, L. Schnell, S. Fischer, B. K. Agrawalla, P. Winterwerber, E. Wirsching, M. Fauler, M. Frick, S. L. Kuan, T. Weil and H. Barth, "Supramolecular Toxin Complexes for Targeted Pharmacological Modulation of Polymorphonuclear Leukocyte Functions", Adv Healthc Mater, vol. 8, no. 17, pp. e1900665, 2019.
DOI:10.1002/adhm.201900665
Datei:https://www.ncbi.nlm.nih.gov/pubmed/31318180 https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/adhm.201900665?download=true
205.
E. Karasu, B. Nilsson, J. Kohl and J. D. Lambris, "Targeting Complement Pathways in Polytrauma- and Sepsis-Induced Multiple-Organ Dysfunction", Front Immunol, vol. 10, pp. 543, 2019.
DOI:10.3389/fimmu.2019.00543
Datei:pdfhttps://www.ncbi.nlm.nih.gov/pubmed/30949180 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437067/pdf/fimmu-10-00543.pdf
204.
U. Wachter, B. Lukaschewski, S. Häfner, M. Georgieff, N. Nagahara, C. Szabo and P. Radermacher, "The Effects of Genetic 3-Mercaptopyruvate Sulfurtransferase Deficiency in Murine Traumatic-Hemorrhagic Shock", Shock, vol. 51, no. 4, pp. 472-478, 2019.
DOI:10.1097/SHK.0000000000001165
Datei:pdfhttps://www.ncbi.nlm.nih.gov/pubmed/29668565 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6192867/pdf/nihms959306.pdf
203.
U. Wachter, B. Lukaschewski, G. Rumm, M. Georgieff, R. Torregrossa, M. Whiteman and P. Radermacher, "The Mitochondria-Targeted H2S-Donor AP39 in a Murine Model of Combined Hemorrhagic Shock and Blunt Chest Trauma", Shock, vol. 52, no. 2, pp. 230-239, 2019.
DOI:10.1097/SHK.0000000000001210
Datei:https://www.ncbi.nlm.nih.gov/pubmed/29927788
202.
R. Wanner, A. Abaei, V. Rasche and B. Knöll, "Three-Dimensional In vivo Magnetic Resonance Imaging (MRI) of Mouse Facial Nerve Regeneration", Front Neurol, vol. 10, pp. 310, 2019.
DOI:10.3389/fneur.2019.00310
Datei:pdfhttps://www.ncbi.nlm.nih.gov/pubmed/31001195 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454117/pdf/fneur-10-00310.pdf
201.
B. Weber, M. R. Mendler, J. Pressmar, S. Hofler, C. K. Braun, H. Hummler, S. Schwarz and M. Kalbitz, "Tissue damage in the heart after cardiac arrest induced by asphyxia and hemorrhage in newborn pigs", Pediatr Res, vol. 86, no. 6, pp. 709-718, 2019.
DOI:10.1038/s41390-019-0505-6
Datei:https://www.ncbi.nlm.nih.gov/pubmed/31336381
200.
F. Roselli, "TREM1-ors shake the brain and gut after stroke", Nat Immunol, vol. 20, no. 8, pp. 950-952, 2019.
DOI:10.1038/s41590-019-0443-9
Datei:pdfhttps://www.ncbi.nlm.nih.gov/pubmed/31285627 https://www.nature.com/articles/s41590-019-0443-9.pdf

2018

199.
V. Clemens, P. L. Plener, E. Brahler, R. C. Brown and J. M. Fegert, "Association of child maltreatment subtypes and long-term physical health in a German representative sample", Eur J Psychotraumatol, vol. 9, no. 1, pp. 1510278, 2018.
DOI:10.1080/20008198.2018.1510278
Datei:https://www.ncbi.nlm.nih.gov/pubmed/30220980
198.
R. C. Brown, P. L. Plener, E. Braehler and J. M. Fegert, "Associations of adverse childhood experiences and bullying on physical pain in the general population of Germany", J Pain Res, vol. 11, pp. 3099-3108, 2018.
DOI:10.2147/JPR.S169135
Datei:https://www.ncbi.nlm.nih.gov/pubmed/30584352
197.
J. Gačanin, J. Hedrich, S. Sieste, G. Glasser, I. Lieberwirth, C. Schilling, S. Fischer, H. Barth, B. Knöll, C. V. Synatschke and T. Weil, "Autonomous Ultrafast Self-Healing Hydrogels by pH-Responsive Functional Nanofiber Gelators as Cell Matrices", Adv Mater, vol. In Press, no. 2, pp. e1805044, 2018.
DOI:10.1002/adma.201805044
Datei:https://www.ncbi.nlm.nih.gov/pubmed/30411838
196.
K. N. Ekdahl, R. Wiegner, K. Fromell and B. Nilsson, "Auxiliary activation of the complement system and its importance for the pathophysiology of clinical conditions", Semin Immunopathol, vol. 40, no. 1, pp. 87-102, 2018.
DOI:10.1007/s00281-017-0646-9
Datei:https://www.ncbi.nlm.nih.gov/pubmed/28900700
195.
J. Demiselle and P. Radermacher, "Before the ICU: does emergency room hyperoxia affect outcome?", Crit Care, vol. 22, no. 1, pp. 59, 2018.
DOI:10.1186/s13054-018-1980-6
Datei:https://www.ncbi.nlm.nih.gov/pubmed/29519235
194.
S. L. Kuan, S. Fischer, S. Häfner, T. Syrovets, W. Liu, Y. Tokura, D. Y. W. Ng, A. Riegger, C. Förtsch, D. Jager, T. F. E. Barth, T. Simmet, H. Barth and T. Weil, "Boosting Antitumor Drug Efficacy with Chemically Engineered Multidomain Proteins", Adv Sci (Weinh), vol. 5, no. 8, pp. 1701036, 2018.
DOI:10.1002/advs.201701036
Datei:https://www.ncbi.nlm.nih.gov/pubmed/30128225
193.
Y. Mödinger, A. Rapp, J. Pazmandi, A. Vikman, K. Holzmann, M. Haffner-Luntzer, M. Huber-Lang and A. Ignatius, "C5aR1 interacts with TLR2 in osteoblasts and stimulates the osteoclast-inducing chemokine CXCL10", J Cell Mol Med, vol. 22, no. 12, pp. 6002-6014, 2018.
DOI:10.1111/jcmm.13873
Datei:https://onlinelibrary.wiley.com/doi/abs/10.1111/jcmm.13873
192.
V. Fischer, "Calcium and vitamin D in bone fracture healing and post-traumatic bone turnover", Eur Cell Mater, vol. 35, pp. 365-385, 2018.
DOI:10.22203/eCM.v035a25
Datei:https://www.ncbi.nlm.nih.gov/pubmed/29931664
191.
"Cell-based RNAi screening and high-content analysis in primary calvarian osteoblasts applied to identification of osteoblast differentiation regulators", Sci Rep, vol. 8, no. 1, pp. 14045, 2018.
DOI:10.1038/s41598-018-32364-8
Datei:https://www.ncbi.nlm.nih.gov/pubmed/30232406
190.
J. U. Werner, K. Todter, P. Xu, L. Lockhart, M. Jahnert, P. Gottmann, A. Schurmann, L. Scheja, M. Wabitsch and U. Knippschild, "Comparison of Fatty Acid and Gene Profiles in Skeletal Muscle in Normal and Obese C57BL/6J Mice before and after Blunt Muscle Injury", Front Physiol, vol. 9, pp. 19, 2018.
DOI:10.3389/fphys.2018.00019
Datei:https://www.ncbi.nlm.nih.gov/pubmed/29441023
189.
S. Chakraborty and E. Karasu, "Complement After Trauma: Suturing Innate and Adaptive Immunity", Front Immunol, vol. 9, pp. 2050, 2018.
DOI:10.3389/fimmu.2018.02050
Datei:https://www.ncbi.nlm.nih.gov/pubmed/30319602
188.
D. A. C. Messerer, S. Denk, K. J. Fohr, C. K. Braun, F. Hones, J. Harant, M. Fauler, M. Frick, B. L. Nussbaum, P. Radermacher, S. Häfner and M. S. Huber-Lang, "Complement C5a Alters the Membrane Potential of Neutrophils during Hemorrhagic Shock", Mediators Inflamm, vol. 2018, pp. 2052356, 2018.
DOI:10.1155/2018/2052356
Datei:https://www.ncbi.nlm.nih.gov/pubmed/30002598
187.
B. Nussbaum, R. Wang, C. Szabo and P. Radermacher, "Cystathionine-gamma-lyase expression is associated with mitochondrial respiration during sepsis-induced acute kidney injury in swine with atherosclerosis", Intensive Care Med Exp, vol. 6, no. 1, pp. 43, 2018.
DOI:10.1186/s40635-018-0208-z
Datei:https://www.ncbi.nlm.nih.gov/pubmed/30343340
186.
C. Zhang, "Deletion of Menin in craniofacial osteogenic cells in mice elicits development of mandibular ossifying fibroma", Oncogene, vol. 37, no. 5, pp. 616-626, 2018.
DOI:10.1038/onc.2017.364
Datei:https://www.ncbi.nlm.nih.gov/pubmed/28991228
185.
P. Xu, J. U. Werner, S. Milerski, C. M. Hamp, T. Kuzenko, M. Jahnert, P. Gottmann, L. Roy, D. Warnecke, A. Abaei, A. Palmer, L. Dürselen, V. Rasche, A. Schurmann, M. Wabitsch and U. Knippschild, "Diet-Induced Obesity Affects Muscle Regeneration After Murine Blunt Muscle Trauma-A Broad Spectrum Analysis", Front Physiol, vol. 9, pp. 674, 2018.
DOI:10.3389/fphys.2018.00674
Datei:https://www.ncbi.nlm.nih.gov/pubmed/29922174
184.
K. Prystaz, K. Kaiser, V. Fischer, A. E. Rapp and G. H. Waetzig, "Distinct Effects of IL-6 Classic and Trans-Signaling in Bone Fracture Healing", Am J Pathol, vol. 188, no. 2, pp. 474-490, 2018.
DOI:10.1016/j.ajpath.2017.10.011
Datei:https://www.ncbi.nlm.nih.gov/pubmed/29146294
183.
V. Fischer, "Effects of low-magnitude high-frequency vibration on osteoblasts are dependent on estrogen receptor alpha signaling and cytoskeletal remodeling", Biochem Biophys Res Commun, vol. 503, no. 4, pp. 2678-2684, 2018.
DOI:10.1016/j.bbrc.2018.08.023
Datei:https://www.ncbi.nlm.nih.gov/pubmed/30093109
182.
P. D. Fromm and D. Chen, "Endogenous glucocorticoid signaling in chondrocytes attenuates joint inflammation and damage", FASEB J, vol. 32, no. 1, pp. 478-487, 2018.
DOI:10.1096/fj.201700659R
Datei:https://www.ncbi.nlm.nih.gov/pubmed/28928247
181.
"Estrogen receptor alpha- (ERalpha), but not ERbeta-signaling, is crucially involved in mechanostimulation of bone fracture healing by whole-body vibration", Bone, vol. 110, pp. 11-20, 2018.
DOI:10.1016/j.bone.2018.01.017
Datei:https://www.ncbi.nlm.nih.gov/pubmed/29367057
180.
"Glucocorticoid receptor in stromal cells is essential for glucocorticoid-mediated suppression of inflammation in arthritis", Ann Rheum Dis, vol. 77, no. 11, pp. 1610-1618, 2018.
DOI:10.1136/annrheumdis-2017-212762
Datei:https://www.ncbi.nlm.nih.gov/pubmed/29997111
179.
"Glucocorticoids suppress Wnt16 expression in osteoblasts in vitro and in vivo", Sci Rep, vol. 8, no. 1, pp. 8711, 2018.
DOI:10.1038/s41598-018-26300-z
Datei:https://www.ncbi.nlm.nih.gov/pubmed/29880826
178.
O. Lesur, E. Delile and P. Radermacher, "Hemodynamic support in the early phase of septic shock: a review of challenges and unanswered questions", Ann Intensive Care, vol. 8, no. 1, pp. 102, 2018.
DOI:10.1186/s13613-018-0449-8
Datei:https://www.ncbi.nlm.nih.gov/pubmed/30374729
177.
C. K. Braun, S. Denk, B. Mayer, P. Cinelli, P. Radermacher, G. A. Wanner, H. P. Simmen, F. Gebhard and D. Rittirsch, "Hemorrhagic shock drives glycocalyx, barrier and organ dysfunction early after polytrauma", J Crit Care, vol. 44, pp. 229-237, 2018.
DOI:10.1016/j.jcrc.2017.11.025
Datei:https://www.ncbi.nlm.nih.gov/pubmed/29175047
176.
J. Demiselle, P. Radermacher, F. Schortgen, F. Meziani, M. Singer, V. Seegers and H. S. investigators, "Hyperoxia toxicity in septic shock patients according to the Sepsis-3 criteria: a post hoc analysis of the HYPER2S trial", Ann Intensive Care, vol. 8, no. 1, pp. 90, 2018.
DOI:10.1186/s13613-018-0435-1
Datei:https://www.ncbi.nlm.nih.gov/pubmed/30225670
175.
M. Mettang, S. N. Reichel, M. Lattke, A. Palmer, A. Abaei, V. Rasche and T. Wirth, "IKK2/NF-kappaB signaling protects neurons after traumatic brain injury", FASEB J, vol. 32, no. 4, pp. 1916-1932, 2018.
DOI:10.1096/fj.201700826R
Datei:https://www.ncbi.nlm.nih.gov/pubmed/29187362
174.
A. E. Rapp, "Induced global deletion of glucocorticoid receptor impairs fracture healing", FASEB J, vol. 32, no. 4, pp. 2235-2245, 2018.
DOI:10.1096/fj.201700459RR
Datei:https://www.ncbi.nlm.nih.gov/pubmed/29217668
173.
V. Fischer, M. Kalbitz, F. Muller-Graf and F. Gebhard, "Influence of Menopause on Inflammatory Cytokines during Murine and Human Bone Fracture Healing", Int J Mol Sci, vol. 19, no. 7, pp. 2070, 2018.
DOI:10.3390/ijms19072070
Datei:https://www.ncbi.nlm.nih.gov/pubmed/30013010
172.
J. D. Lambris and P. A. Ward, "Innate immune responses to trauma", Nat Immunol, vol. 19, no. 4, pp. 327-341, 2018.
DOI:10.1038/s41590-018-0064-8
Datei:https://www.ncbi.nlm.nih.gov/pubmed/29507356
171.
B. Lukaschewski, A. Rupprecht, M. Whiteman, C. Szabo, R. Wang and P. Radermacher, "Interaction of the hydrogen sulfide system with the oxytocin system in the injured mouse heart", Intensive Care Med Exp, vol. 6, no. 1, pp. 41, 2018.
DOI:10.1186/s40635-018-0207-0
Datei:https://www.ncbi.nlm.nih.gov/pubmed/30341744
170.
F. Roselli, A. Chandrasekar and M. C. Morganti-Kossmann, "Interferons in Traumatic Brain and Spinal Cord Injury: Current Evidence for Translational Application", Front Neurol, vol. 9, pp. 458, 2018.
DOI:10.3389/fneur.2018.00458
Datei:pdfhttps://www.ncbi.nlm.nih.gov/pubmed/29971040 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6018073/pdf/fneur-09-00458.pdf