Zusammenstellung von Bildern aus dem Sonderforschungsbereich

Publikationen aus dem SFB 1149

2018

164.
M. Huber-Lang, K. N. Ekdahl, R. Wiegner, K. Fromell and B. Nilsson, "Auxiliary activation of the complement system and its importance for the pathophysiology of clinical conditions", Semin Immunopathol, vol. 40, no. 1, pp. 87-102, 2018.
DOI:10.1007/s00281-017-0646-9
Datei:https://www.ncbi.nlm.nih.gov/pubmed/28900700
163.
M. Wepler, J. Demiselle, P. Radermacher, P. Asfar and E. Calzia, "Before the ICU: does emergency room hyperoxia affect outcome?", Crit Care, vol. 22, no. 1, pp. 59, 2018.
DOI:10.1186/s13054-018-1980-6
Datei:https://www.ncbi.nlm.nih.gov/pubmed/29519235
162.
S. L. Kuan, S. Fischer, S. Häfner, T. Wang, T. Syrovets, W. Liu, Y. Tokura, D. Y. W. Ng, A. Riegger, C. Förtsch, D. Jager, T. F. E. Barth, T. Simmet, H. Barth and T. Weil, "Boosting Antitumor Drug Efficacy with Chemically Engineered Multidomain Proteins", Adv Sci (Weinh), vol. 5, no. 8, pp. 1701036, 2018.
DOI:10.1002/advs.201701036
Datei:https://www.ncbi.nlm.nih.gov/pubmed/30128225
161.
Y. Mödinger, A. Rapp, J. Pazmandi, A. Vikman, K. Holzmann, M. Haffner-Luntzer, M. Huber-Lang and A. Ignatius, "C5aR1 interacts with TLR2 in osteoblasts and stimulates the osteoclast-inducing chemokine CXCL10", J Cell Mol Med, vol. 22, no. 12, pp. 6002-6014, 2018.
DOI:10.1111/jcmm.13873
Datei:https://onlinelibrary.wiley.com/doi/abs/10.1111/jcmm.13873
160.
V. Fischer, M. Haffner-Luntzer, M. Amling and A. Ignatius, "Calcium and vitamin D in bone fracture healing and post-traumatic bone turnover", Eur Cell Mater, vol. 35, pp. 365-385, 2018.
DOI:10.22203/eCM.v035a25
Datei:https://www.ncbi.nlm.nih.gov/pubmed/29931664
159.
M. Ahmad, T. Kroll, J. Jakob, A. Rauch, A. Ploubidou and J. Tuckermann, "Cell-based RNAi screening and high-content analysis in primary calvarian osteoblasts applied to identification of osteoblast differentiation regulators", Sci Rep, vol. 8, no. 1, pp. 14045, 2018.
DOI:10.1038/s41598-018-32364-8
Datei:https://www.ncbi.nlm.nih.gov/pubmed/30232406
158.
J. U. Werner, K. Todter, P. Xu, L. Lockhart, M. Jahnert, P. Gottmann, A. Schurmann, L. Scheja, M. Wabitsch and U. Knippschild, "Comparison of Fatty Acid and Gene Profiles in Skeletal Muscle in Normal and Obese C57BL/6J Mice before and after Blunt Muscle Injury", Front Physiol, vol. 9, pp. 19, 2018.
DOI:10.3389/fphys.2018.00019
Datei:https://www.ncbi.nlm.nih.gov/pubmed/29441023
157.
S. Chakraborty, E. Karasu and M. Huber-Lang, "Complement After Trauma: Suturing Innate and Adaptive Immunity", Front Immunol, vol. 9, pp. 2050, 2018.
DOI:10.3389/fimmu.2018.02050
Datei:https://www.ncbi.nlm.nih.gov/pubmed/30319602
156.
D. A. C. Messerer, S. Denk, K. J. Fohr, R. Halbgebauer, C. K. Braun, F. Hones, J. Harant, M. Fauler, M. Frick, B. L. Nussbaum, P. Radermacher, S. Häfner and M. S. Huber-Lang, "Complement C5a Alters the Membrane Potential of Neutrophils during Hemorrhagic Shock", Mediators Inflamm, vol. 2018, pp. 2052356, 2018.
DOI:10.1155/2018/2052356
Datei:https://www.ncbi.nlm.nih.gov/pubmed/30002598
155.
R. C. Brown, P. L. Plener, E. Braehler, J. M. Fegert and M. Huber-Lang, "Associations of adverse childhood experiences and bullying on physical pain in the general population of Germany", J Pain Res, vol. 11, pp. 3099-3108, 2018.
DOI:10.2147/JPR.S169135
Datei:https://www.ncbi.nlm.nih.gov/pubmed/30584352
154.
S. Lee, P. Liu, R. Teinturier, J. Jakob, M. Tschaffon, A. Tasdogan, R. Wittig, S. Hoeller, D. Baumhoer, L. Frappart, S. Vettorazzi, P. Bertolino, C. Zhang and J. Tuckermann, "Deletion of Menin in craniofacial osteogenic cells in mice elicits development of mandibular ossifying fibroma", Oncogene, vol. 37, no. 5, pp. 616-626, 2018.
DOI:10.1038/onc.2017.364
Datei:https://www.ncbi.nlm.nih.gov/pubmed/28991228
153.
O. Lesur, E. Delile, P. Asfar and P. Radermacher, "Hemodynamic support in the early phase of septic shock: a review of challenges and unanswered questions", Ann Intensive Care, vol. 8, no. 1, pp. 102, 2018.
DOI:10.1186/s13613-018-0449-8
Datei:https://www.ncbi.nlm.nih.gov/pubmed/30374729
152.
P. Xu, J. U. Werner, S. Milerski, C. M. Hamp, T. Kuzenko, M. Jahnert, P. Gottmann, L. Roy, D. Warnecke, A. Abaei, A. Palmer, M. Huber-Lang, L. Dürselen, V. Rasche, A. Schurmann, M. Wabitsch and U. Knippschild, "Diet-Induced Obesity Affects Muscle Regeneration After Murine Blunt Muscle Trauma-A Broad Spectrum Analysis", Front Physiol, vol. 9, pp. 674, 2018.
DOI:10.3389/fphys.2018.00674
Datei:https://www.ncbi.nlm.nih.gov/pubmed/29922174
151.
M. Mettang, S. N. Reichel, M. Lattke, A. Palmer, A. Abaei, V. Rasche, M. Huber-Lang, B. Baumann and T. Wirth, "IKK2/NF-kappaB signaling protects neurons after traumatic brain injury", FASEB J, vol. 32, no. 4, pp. 1916-1932, 2018.
DOI:10.1096/fj.201700826R
Datei:https://www.ncbi.nlm.nih.gov/pubmed/29187362
150.
J. Demiselle, M. Wepler, C. Hartmann, P. Radermacher, F. Schortgen, F. Meziani, M. Singer, V. Seegers, P. Asfar and H. S. investigators, "Hyperoxia toxicity in septic shock patients according to the Sepsis-3 criteria: a post hoc analysis of the HYPER2S trial", Ann Intensive Care, vol. 8, no. 1, pp. 90, 2018.
DOI:10.1186/s13613-018-0435-1
Datei:https://www.ncbi.nlm.nih.gov/pubmed/30225670
149.
R. Halbgebauer, C. K. Braun, S. Denk, B. Mayer, P. Cinelli, P. Radermacher, G. A. Wanner, H. P. Simmen, F. Gebhard, D. Rittirsch and M. Huber-Lang, "Hemorrhagic shock drives glycocalyx, barrier and organ dysfunction early after polytrauma", J Crit Care, vol. 44, pp. 229-237, 2018.
DOI:10.1016/j.jcrc.2017.11.025
Datei:https://www.ncbi.nlm.nih.gov/pubmed/29175047
148.
A. E. Rapp, Y. Hachemi, J. Kemmler, M. Koenen, J. Tuckermann and A. Ignatius, "Induced global deletion of glucocorticoid receptor impairs fracture healing", FASEB J, vol. 32, no. 4, pp. 2235-2245, 2018.
DOI:10.1096/fj.201700459RR
Datei:https://www.ncbi.nlm.nih.gov/pubmed/29217668
147.
S. Hildebrandt, U. Baschant, S. Thiele, J. Tuckermann, L. C. Hofbauer and M. Rauner, "Glucocorticoids suppress Wnt16 expression in osteoblasts in vitro and in vivo", Sci Rep, vol. 8, no. 1, pp. 8711, 2018.
DOI:10.1038/s41598-018-26300-z
Datei:https://www.ncbi.nlm.nih.gov/pubmed/29880826
146.
K. Prystaz, K. Kaiser, A. Kovtun, M. Haffner-Luntzer, V. Fischer, A. E. Rapp, A. Liedert, G. Strauss, G. H. Waetzig, S. Rose-John and A. Ignatius, "Distinct Effects of IL-6 Classic and Trans-Signaling in Bone Fracture Healing", Am J Pathol, vol. 188, no. 2, pp. 474-490, 2018.
DOI:10.1016/j.ajpath.2017.10.011
Datei:https://www.ncbi.nlm.nih.gov/pubmed/29146294
145.
M. Haffner-Luntzer, A. Kovtun, I. Lackner, Y. Mödinger, S. Hacker, A. Liedert, J. Tuckermann and A. Ignatius, "Estrogen receptor alpha- (ERalpha), but not ERbeta-signaling, is crucially involved in mechanostimulation of bone fracture healing by whole-body vibration", Bone, vol. 110, pp. 11-20, 2018.
DOI:10.1016/j.bone.2018.01.017
Datei:https://www.ncbi.nlm.nih.gov/pubmed/29367057
144.
J. Tu, S. Stoner, P. D. Fromm, T. Wang, D. Chen, J. Tuckermann, M. S. Cooper, M. J. Seibel and H. Zhou, "Endogenous glucocorticoid signaling in chondrocytes attenuates joint inflammation and damage", FASEB J, vol. 32, no. 1, pp. 478-487, 2018.
DOI:10.1096/fj.201700659R
Datei:https://www.ncbi.nlm.nih.gov/pubmed/28928247
143.
M. Haffner-Luntzer, I. Lackner, A. Liedert, V. Fischer and A. Ignatius, "Effects of low-magnitude high-frequency vibration on osteoblasts are dependent on estrogen receptor alpha signaling and cytoskeletal remodeling", Biochem Biophys Res Commun, vol. 503, no. 4, pp. 2678-2684, 2018.
DOI:10.1016/j.bbrc.2018.08.023
Datei:https://www.ncbi.nlm.nih.gov/pubmed/30093109
142.
M. Koenen, S. Culemann, S. Vettorazzi, G. Caratti, L. Frappart, W. Baum, G. Krönke and U. Baschant, "Glucocorticoid receptor in stromal cells is essential for glucocorticoid-mediated suppression of inflammation in arthritis", Ann Rheum Dis, vol. 77, no. 11, pp. 1610-1618, 2018.
DOI:10.1136/annrheumdis-2017-212762
Datei:https://www.ncbi.nlm.nih.gov/pubmed/29997111

2017

141.
N. Guidi, M. Sacma, L. Standker, K. Soller, G. Marka, K. Eiwen, J. M. Weiss, F. Kirchhoff, T. Weil, J. A. Cancelas, M. C. Florian and H. Geiger, "Osteopontin attenuates aging-associated phenotypes of hematopoietic stem cells", EMBO J, vol. 36, no. 10, pp. 1463, 2017.
DOI:10.15252/embj.201796968
Datei:https://www.ncbi.nlm.nih.gov/pubmed/28507084
140.
S. Bergdolt, A. Kovtun, Y. Hagele, A. Liedert, T. Schinke, M. Amling, M. Huber-Lang and A. Ignatius, "Osteoblast-specific overexpression of complement receptor C5aR1 impairs fracture healing", PLoS One, vol. 12, no. 6, pp. e0179512, 2017.
DOI:10.1371/journal.pone.0179512
Datei:https://www.ncbi.nlm.nih.gov/pubmed/28614388
139.
F. Seichter, J. Vogt, P. Radermacher and B. Mizaikoff, "Nonlinear calibration transfer based on hierarchical Bayesian models and Lagrange Multipliers: Error bounds of estimates via Monte Carlo - Markov Chain sampling", Anal Chim Acta, vol. 951, pp. 32-45, 2017.
DOI:10.1016/j.aca.2016.11.025
Datei:https://www.ncbi.nlm.nih.gov/pubmed/27998484
138.
C. Hartmann, P. Radermacher, M. Wepler and B. Nussbaum, "Non-Hemodynamic Effects of Catecholamines", Shock, vol. 48, no. 4, pp. 390-400, 2017.
DOI:10.1097/SHK.0000000000000879
Datei:https://www.ncbi.nlm.nih.gov/pubmed/28915214
137.
Y. Husecken, S. Muche, M. Kustermann, M. Klingspor, A. Palmer, S. Braumuller, M. Huber-Lang, K. M. Debatin and G. Strauss, "MDSCs are induced after experimental blunt chest trauma and subsequently alter antigen-specific T cell responses", Sci Rep, vol. 7, no. 1, pp. 12808, 2017.
DOI:10.1038/s41598-017-13019-6
Datei:https://www.ncbi.nlm.nih.gov/pubmed/28993671
136.
T. Itkin, A. Kumari, E. Schneider, S. Gur-Cohen, C. Ludwig, O. Kollet, K. Golan, E. Khatib-Massalha, C. M. Russo, J. D. Chisholm, A. Rouhi, H. Geiger, E. Hornstein, W. G. Kerr, F. Kuchenbauer and T. Lapidot, "MicroRNA-155 promotes G-CSF-induced mobilization of murine hematopoietic stem and progenitor cells via propagation of CXCL12 signaling", Leukemia, vol. 31, no. 5, pp. 1247-1250, 2017.
DOI:10.1038/leu.2017.50
Datei:https://www.ncbi.nlm.nih.gov/pubmed/28174416
135.
N. Hagemeyer, K. M. Hanft, M. A. Akriditou, N. Unger, E. S. Park, E. R. Stanley, O. Staszewski, L. Dimou and M. Prinz, "Microglia contribute to normal myelinogenesis and to oligodendrocyte progenitor maintenance during adulthood", Acta Neuropathol, vol. 134, no. 3, pp. 441-458, 2017.
DOI:10.1007/s00401-017-1747-1
Datei:https://www.ncbi.nlm.nih.gov/pubmed/28685323
134.
D. Langgartner, D. Peterlik, S. Foertsch, A. M. Fuchsl, P. Brokmann, P. J. Flor, Z. Shen, J. G. Fox, N. Uschold-Schmidt, C. A. Lowry and S. O. Reber, "Individual differences in stress vulnerability: The role of gut pathobionts in stress-induced colitis", Brain Behav Immun, vol. 64, pp. 23-32, 2017.
DOI:10.1016/j.bbi.2016.12.019
Datei:https://www.ncbi.nlm.nih.gov/pubmed/28012830
133.
P. Liu, S. Lee, J. Knoll, A. Rauch, S. Ostermay, J. Luther, N. Malkusch, U. H. Lerner, M. M. Zaiss, M. Neven, R. Wittig, M. Rauner, J. P. David, P. Bertolino and C. X. Zhang, "Loss of menin in osteoblast lineage affects osteocyte-osteoclast crosstalk causing osteoporosis", Cell Death Differ, vol. 24, no. 4, pp. 672-682, 2017.
DOI:10.1038/cdd.2016.165
Datei:https://www.ncbi.nlm.nih.gov/pubmed/28106886
132.
A. Magadum, Y. Ding, L. He, T. Kim, M. D. Vasudevarao, Q. Long, N. Wickramasinghe, H. V. Renikunta, N. Dubois, G. Weidinger, Q. Yang and F. B. Engel, "Live cell screening platform identifies PPARdelta as a regulator of cardiomyocyte proliferation and cardiac repair", Cell Res, vol. 27, no. 8, pp. 1002-1019, 2017.
DOI:10.1038/cr.2017.84
Datei:https://www.ncbi.nlm.nih.gov/pubmed/28621328
131.
F. Seichter, J. Vogt, P. Radermacher and B. Mizaikoff, "Response-surface fits and calibration transfer for the correction of the oxygen effect in the quantification of carbon dioxide via FTIR spectroscopy", Anal Chim Acta, vol. 972, pp. 16-27, 2017.
DOI:10.1016/j.aca.2017.03.053
Datei:https://www.ncbi.nlm.nih.gov/pubmed/28495092
130.
M. Kalbitz, C. Waller, M. Huber-Lang, F. Gebhard, C. Thiemermann and P. Radermacher, "Oxygen in the Heart: How Much is too Much?", Shock, vol. 47, no. 4, pp. 531-532, 2017.
DOI:10.1097/SHK.0000000000000760
Datei:https://www.ncbi.nlm.nih.gov/pubmed/27749760
129.
M. Haffner-Luntzer, V. Fischer, K. Prystaz, A. Liedert and A. Ignatius, "The inflammatory phase of fracture healing is influenced by oestrogen status in mice", Eur J Med Res, vol. 33, no. 1, pp. 23, 2017.
DOI:10.1186/s40001‐017‐0264‐y
128.
S. Häfner, K. Wagner, S. Weber, M. Gröger, M. Wepler, O. McCook, A. Scheuerle, M. Huber-Lang, B. Jung, E. Calzia, M. Georgieff, P. Möller, M. Frick, P. Radermacher and F. Wagner, "Role of the Purinergic Receptor P2XR4 After Blunt Chest Trauma in Cigarette Smoke-Exposed Mice", Shock, vol. 47, no. 2, pp. 193-199, 2017.
DOI:10.1097/SHK.0000000000000726
Datei:https://www.ncbi.nlm.nih.gov/pubmed/27559703
127.
A. Zimprich, G. Mroz, C. Meyer Zu Reckendorf, S. Anastasiadou, P. Forstner, L. Garrett, S. M. Holter, L. Becker, J. Rozman, C. Prehn, B. Rathkolb, K. Moreth, W. Wurst, T. Klopstock, M. Klingenspor, J. Adamski, E. Wolf, R. Bekeredjian, H. Fuchs, V. Gailus-Durner, M. H. Angelis and B. Knöll, "Serum Response Factor (SRF) Ablation Interferes with Acute Stress-Associated Immediate and Long-Term Coping Mechanisms", Mol Neurobiol, vol. 54, no. 10, pp. 8242-8262, 2017.
DOI:10.1007/s12035-016-0300-x
Datei:https://www.ncbi.nlm.nih.gov/pubmed/27914009
126.
J. Gačanin, A. Kovtun, S. Fischer, V. Schwager, J. Quambusch, S. L. Kuan, W. Liu, F. Boldt, C. Li, Z. Yang, D. Liu, Y. Wu, T. Weil, H. Barth and A. Ignatius, "Spatiotemporally Controlled Release of Rho-Inhibiting C3 Toxin from a Protein–DNA Hybrid Hydrogel for Targeted Inhibition of Osteoclast Formation and Activity", Adv Healthc Mater, vol. 6, no. 21, pp. 1700392, 2017.
DOI:10.1002/adhm.201700392
Datei:http://dx.doi.org/10.1002/adhm.201700392
125.
S. Foertsch, A. M. Fuchsl, S. D. Faller, H. Holzer, D. Langgartner, J. Messmann, G. Strauss and S. O. Reber, "Splenic glucocorticoid resistance following psychosocial stress requires physical injury", Sci Rep, vol. 7, no. 1, pp. 15730, 2017.
DOI:10.1038/s41598-017-15897-2
Datei:https://www.ncbi.nlm.nih.gov/pubmed/29146967
124.
P. Losing, C. E. Niturad, M. Harrer, C. M. Z. Reckendorf, T. Schatz, D. Sinske, H. Lerche, S. Maljevic and B. Knöll, "SRF modulates seizure occurrence, activity induced gene transcription and hippocampal circuit reorganization in the mouse pilocarpine epilepsy model", Mol Brain, vol. 10, no. 1, pp. 30, 2017.
DOI:10.1186/s13041-017-0310-2
Datei:https://www.ncbi.nlm.nih.gov/pubmed/28716058
123.
P. Galuppo, S. Vettorazzi, J. Hövelmann, C. J. Scholz, J. Bauersachs and D. Fraccarollo, "The glucocorticoid receptor in monocyte-derived macrophages is critical for cardiac infarct repair and remodeling", FASEB J, vol. 31, no. 11, pp. 5122-5132, 2017.
DOI:10.1096/fj.201700317R
Datei:https://www.ncbi.nlm.nih.gov/pubmed/28768721
122.
C. Hartmann, S. Häfner, A. Scheuerle, P. Möller, M. Huber-Lang, B. Jung, B. Nubaum, O. McCook, M. Gröger, F. Wagner, S. Weber, E. Calzia, M. Georgieff, C. Szabo, R. Wang, P. Radermacher and K. Wagner, "The Role of Cystathionine-gamma-Lyase In Blunt Chest Trauma in Cigarette Smoke Exposed Mice", Shock, vol. 47, no. 4, pp. 491-499, 2017.
DOI:10.1097/SHK.0000000000000746
Datei:https://www.ncbi.nlm.nih.gov/pubmed/27685807
121.
E. Bonfanti, P. Gelosa, M. Fumagalli, L. Dimou, F. Vigano, E. Tremoli, M. Cimino, L. Sironi and M. P. Abbracchio, "The role of oligodendrocyte precursor cells expressing the GPR17 receptor in brain remodeling after stroke", Cell Death Dis, vol. 8, no. 6, pp. e2871, 2017.
DOI:10.1038/cddis.2017.256
Datei:https://www.ncbi.nlm.nih.gov/pubmed/28594400
120.
M. Kalbitz, J. Pressmar, J. Stecher, B. Weber, M. Weiss, S. Schwarz, E. Miltner, F. Gebhard and M. Huber-Lang, "The Role of Troponin in Blunt Cardiac Injury After Multiple Trauma in Humans", World J Surg, vol. 41, no. 1, pp. 162-169, 2017.
DOI:10.1007/s00268-016-3650-7
Datei:https://www.ncbi.nlm.nih.gov/pubmed/27501709
119.
M. Lattke, S. N. Reichel, A. Magnutzki, A. Abaei, V. Rasche, P. Walther, D. P. Calado, B. Ferger, T. Wirth and B. Baumann, "Transient IKK2 activation in astrocytes initiates selective non-cell-autonomous neurodegeneration", Mol Neurodegener, vol. 12, no. 1, pp. 16, 2017.
DOI:10.1186/s13024-017-0157-0
Datei:https://www.ncbi.nlm.nih.gov/pubmed/28193238
118.
D. Wehner, T. M. Tsarouchas, A. Michael, C. Haase, G. Weidinger, M. M. Reimer, T. Becker and C. G. Becker, "Wnt signaling controls pro-regenerative Collagen XII in functional spinal cord regeneration in zebrafish", Nat Commun, vol. 8, no. 1, pp. 126, 2017.
DOI:10.1038/s41467-017-00143-0
Datei:https://www.ncbi.nlm.nih.gov/pubmed/28743881
117.
S. Pfaender, A. K. Sauer, S. Hagmeyer, K. Mangus, L. Linta, S. Liebau, J. Bockmann, G. Huguet, T. Bourgeron, T. M. Boeckers and A. M. Grabrucker, "Zinc deficiency and low enterocyte zinc transporter expression in human patients with autism related mutations in SHANK3", Sci Rep, vol. 7, pp. 45190, 2017.
DOI:10.1038/srep45190
Datei:https://www.ncbi.nlm.nih.gov/pubmed/28345660
116.
M. C. Sportelli, E. Tutuncu, R. A. Picca, M. Valentini, A. Valentini, C. Kranz, B. Mizaikoff, H. Barth and N. Cioffi, "Inhibiting P. fluorescens biofilms with fluoropolymer-embedded silver nanoparticles: an in-situ spectroscopic study", Sci Rep, vol. 7, no. 1, pp. 11870, 2017.
DOI:10.1038/s41598-017-12088-x
Datei:https://www.ncbi.nlm.nih.gov/pubmed/28928400
115.
J. Kroner, A. Kovtun, J. Kemmler, J. J. Messmann, G. Strauss, S. Seitz, T. Schinke, M. Amling, J. Kotrba, J. Dudeck, A. Dudeck and A. Ignatius, "Mast cells are critical regulators of bone fracture-induced inflammation and osteoclast formation and activity", J Bone Miner Res, vol. 32, no. 12, pp. 2431–2444, 2017.
DOI:10.1002/jbmr.3234
Datei:https://www.ncbi.nlm.nih.gov/pubmed/28777474