Zusammenstellung von Bildern aus dem Sonderforschungsbereich


M. Gröger, M. Wepler, U. Wachter, T. Merz, O. McCook, S. Kress, B. Lukaschewski, S. Häfner, M. Huber-Lang, E. Calzia, M. Georgieff, N. Nagahara, C. Szabo, P. Radermacher and C. Hartmann, "The Effects of Genetic 3-Mercaptopyruvate Sulfurtransferase Deficiency in Murine Traumatic-Hemorrhagic Shock", Shock, vol. 51, no. 4, pp. 472-478, 2019.
Datei:pdfhttps://www.ncbi.nlm.nih.gov/pubmed/29668565 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6192867/pdf/nihms959306.pdf
M. Wepler, T. Merz, U. Wachter, J. Vogt, E. Calzia, A. Scheuerle, P. Möller, M. Gröger, S. Kress, M. Fink, B. Lukaschewski, G. Rumm, B. Stahl, M. Georgieff, M. Huber-Lang, R. Torregrossa, M. Whiteman, O. McCook, P. Radermacher and C. Hartmann, "The Mitochondria-Targeted H2S-Donor AP39 in a Murine Model of Combined Hemorrhagic Shock and Blunt Chest Trauma", Shock, vol. 52, no. 2, pp. 230-239, 2019.
I. Lackner, B. Weber, M. Baur, M. Haffner-Luntzer, T. Eiseler, G. Fois, F. Gebhard, B. Relja, I. Marzi, R. Pfeifer, S. Halvachizadeh, M. Lipiski, N. Cesarovic, H. C. Pape, M. Kalbitz and T. R. Group, "Midkine Is Elevated After Multiple Trauma and Acts Directly on Human Cardiomyocytes by Altering Their Functionality and Metabolism", Front Immunol, vol. 10, pp. 1920, 2019.
Datei:pdfhttps://www.ncbi.nlm.nih.gov/pubmed/31552013 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6736577/pdf/fimmu-10-01920.pdf
F. Roselli and M. Huber-Lang, "TREM1-ors shake the brain and gut after stroke", Nat Immunol, vol. 20, no. 8, pp. 950-952, 2019.
Datei:pdfhttps://www.ncbi.nlm.nih.gov/pubmed/31285627 https://www.nature.com/articles/s41590-019-0443-9.pdf
B. Weber, I. Lackner, M. Haffner-Luntzer, A. Palmer, J. Pressmar, K. Scharffetter-Kochanek, B. Knöll, H. Schrezenmeier, B. Relja and M. Kalbitz, "Modeling trauma in rats: similarities to humans and potential pitfalls to consider", J Transl Med, vol. 17, no. 1, pp. 305, 2019.
B. Weber, M. R. Mendler, I. Lackner, J. Pressmar, M. Haffner-Luntzer, S. Hofler, C. Braun, H. Hummler, S. Schwarz and M. Kalbitz, "Tissue damage in the heart after cardiac arrest induced by asphyxia and hemorrhage in newborn pigs", Pediatr Res, vol. 86, no. 6, pp. 709-718, 2019.
B. Weber, M. R. Mendler, I. Lackner, A. Zelewski, S. Hofler, M. Baur, C. K. Braun, H. Hummler, S. Schwarz, J. Pressmar and M. Kalbitz, "Lung injury after asphyxia and hemorrhagic shock in newborn piglets: Analysis of structural and inflammatory changes", Plos One, vol. 14, no. 7, pp. 14, 2019.
L. Escoter-Torres, G. Caratti, A. Mechtidou, J. Tuckermann, N. H. Uhlenhaut and S. Vettorazzi, "Fighting the Fire: Mechanisms of Inflammatory Gene Regulation by the Glucocorticoid Receptor", Front Immunol, vol. 10, pp. 1859, 2019.
Datei:pdfhttps://www.ncbi.nlm.nih.gov/pubmed/31440248 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6693390/pdf/fimmu-10-01859.pdf
H. P. Muller, D. Brenner, F. Roselli, D. Wiesner, A. Abaei, M. Gorges, K. M. Danzer, A. C. Ludolph, W. Tsao, P. C. Wong, V. Rasche, J. H. Weishaupt and J. Kassubek, "Longitudinal diffusion tensor magnetic resonance imaging analysis at the cohort level reveals disturbed cortical and callosal microstructure with spared corticospinal tract in the TDP-43 (G298S) ALS mouse model", Transl Neurodegener, vol. 8, pp. 27, 2019.
Datei:pdfhttps://www.ncbi.nlm.nih.gov/pubmed/31485326 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6716821/pdf/40035_2019_Article_163.pdf
M. Haffner-Luntzer, K. D. Hankenson, A. Ignatius, R. Pfeifer, B. A. Khader, F. Hildebrand, M. Griensven, H. C. Pape and M. Lehmicke, "A Review of Animal Models of Comorbidities in Fracture-Healing Research", J Orthop Res, vol. 37, no. 12, pp. 2491-2498, 2019.
T. O'Connor, X. Zhou, J. Kosla, A. Adili, M. Garcia Beccaria, E. Kotsiliti, D. Pfister, A. L. Johlke, A. Sinha, R. Sankowski, M. Schick, R. Lewis, N. Dokalis, B. Seubert, B. Hochst, D. Inverso, D. Heide, W. Zhang, P. Weihrich, K. Manske, D. Wohlleber, M. Anton, A. Hoellein, G. Seleznik, J. Bremer, S. Bleul, H. G. Augustin, F. Scherer, U. Koedel, A. Weber, U. Protzer, R. Förster, T. Wirth, A. Aguzzi, F. Meissner, M. Prinz, B. Baumann, U. E. Hopken, P. A. Knolle, L. Baumgarten, U. Keller and M. Heikenwalder, "Age-Related Gliosis Promotes Central Nervous System Lymphoma through CCL19-Mediated Tumor Cell Retention", Cancer Cell, vol. 36, no. 3, pp. 250-267 e9, 2019.
T. Datzmann, M. Wepler, U. Wachter, J. A. Vogt, O. McCook, T. Merz, E. Calzia, M. Gröger, C. Hartmann, P. Asfar, P. Radermacher and B. L. Nussbaum, "Cardiac Effects of Hyperoxia During Resuscitation From Hemorrhagic Shock in Swine", Shock, vol. 52, no. 4, pp. e52-e59, 2019.
F. Haussner, S. Chakraborty, R. Halbgebauer and M. Huber-Lang, "Challenge to the Intestinal Mucosa During Sepsis", Front Immunol, vol. 10, pp. 891, 2019.
Datei:pdfhttps://www.ncbi.nlm.nih.gov/pubmed/31114571 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6502990/pdf/fimmu-10-00891.pdf
M. Haffner-Luntzer, S. Foertsch, V. Fischer, K. Prystaz, M. Tschaffon, Y. Mödinger, C. S. Bahney, R. S. Marcucio, T. Miclau, A. Ignatius and S. O. Reber, "Chronic psychosocial stress compromises the immune response and endochondral ossification during bone fracture healing via β-AR signaling", Proc Natl Acad Sci U S A, vol. 116, no. 117, pp. 8615-8622, 2019.
M. Vogel, H. Christow, I. Manz, M. Denkinger, A. Amoah, D. Schutz, A. Brown, B. Mohrle, A. Schaffer, M. Kalbitz, F. Gebhard, B. Mayer, M. Huber-Lang and H. Geiger, "Distinct Dynamics of Stem and Progenitor Cells in Blood of Polytraumatized Patients", Shock, vol. 51, no. 4, pp. 430-438, 2019.
Datei:pdfhttps://www.ncbi.nlm.nih.gov/pubmed/30289853 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6407807/pdf/shk-51-430.pdf
D. Langgartner, U. Wachter, C. Hartmann, M. Gröger, J. Vogt, T. Merz, O. McCook, M. Fink, S. Kress, M. Georgieff, J. F. Kunze, P. L. Radermacher, S. O. Reber and M. Wepler, "Effects of Psychosocial Stress on Subsequent Hemorrhagic Shock and Resuscitation in Male Mice", Shock, vol. 51, no. 6, pp. 725-730, 2019.
P. Pfänder, M. Fidan, U. Burret, L. Lipinski and S. Vettorazzi, "Cdk5 Deletion Enhances the Anti-inflammatory Potential of GC-Mediated GR Activation During Inflammation", Front Immunol, vol. 10, pp. 1554, 2019.
Datei:pdfhttps://www.ncbi.nlm.nih.gov/pubmed/31354714 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6635475/pdf/fimmu-10-01554.pdf
L. Weert, J. C. Buurstede, H. C. M. Sips, S. Vettorazzi, I. M. Mol, J. Hartmann, S. Prekovic, W. Zwart, M. V. Schmidt, B. Roozendaal, J. P. Tuckermann, R. A. Sarabdjitsingh and O. C. Meijer, "Identification of mineralocorticoid receptor target genes in the mouse hippocampus", J Neuroendocrinol, vol. 31, no. 8, pp. e12735, 2019.
Datei:pdfhttps://www.ncbi.nlm.nih.gov/pubmed/31121060 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6771480/pdf/JNE-31-na.pdf
K. Schuetze, A. Eickhoff, C. Dehner, F. Gebhard and P. H. Richter, "Impact of oral anticoagulation on proximal femur fractures treated within 24 h - A retrospective chart review", Injury, vol. 50, no. 11, pp. 2040-2044, 2019.
M. Wepler, J. M. Preuss, T. Merz, C. Hartmann, U. Wachter, O. McCook, J. Vogt, S. Kress, M. Gröger, M. Fink, A. Scheuerle, P. Möller, E. Calzia, U. Burret, P. Radermacher, J. P. Tuckermann and S. Vettorazzi, "Impaired Glucocorticoid Receptor Dimerization Aggravates LPS-Induced Circulatory and Pulmonary Dysfunction", Front Immunol, vol. 10, pp. 3152, 2019.
N. Tappenbeck, H. M. Schroder, E. Niebergall-Roth, F. Hassinger, U. Dehio, K. Dieter, K. Kraft, A. Kerstan, J. Esterlechner, N. Y. Frank, K. Scharffetter-Kochanek, G. F. Murphy, D. P. Orgill, J. Beck, M. H. Frank, C. Ganss and M. A. Kluth, "In vivo safety profile and biodistribution of GMP-manufactured human skin-derived ABCB5-positive mesenchymal stromal cells for use in clinical trials", Cytotherapy, vol. 21, no. 5, pp. 546-560, 2019.
Datei:pdfhttps://www.ncbi.nlm.nih.gov/pubmed/30878384 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6513723/pdf/nihms-1027450.pdf
C. Hartmann, M. Gröger, J. P. Noirhomme, A. Scheuerle, P. Möller, U. Wachter, M. Huber-Lang, B. Nussbaum, B. Jung, T. Merz, O. McCook, S. Kress, B. Stahl, E. Calzia, M. Georgieff, P. Radermacher and M. Wepler, "In-Depth Characterization of the Effects of Cigarette Smoke Exposure on the Acute Trauma Response and Hemorrhage in Mice", Shock, vol. 51, no. 1, pp. 68-77, 2019.
V. E. Winkelmann, K. E. Thompson, K. Neuland, A. M. Jaramillo, G. Fois, H. Schmidt, O. H. Wittekindt, W. Han, M. J. Tuvim, B. F. Dickey, P. Dietl and M. Frick, "Inflammation-induced upregulation of P2X4 expression augments mucin secretion in airway epithelia", Am J Physiol Lung Cell Mol Physiol, vol. 316, no. 1, pp. L58-L70, 2019.
Datei:https://www.ncbi.nlm.nih.gov/pubmed/30358443 https://journals.physiology.org/doi/pdf/10.1152/ajplung.00157.2018
E. M. Amann, A. Groß, M. T. Rojewski, H. A. Kestler, M. Kalbitz, R. E. Brenner, M. Huber-Lang and H. Schrezenmeier, "Inflammatory response of mesenchymal stromal cells after in vivo exposure with selected trauma-related factors and polytrauma serum", PLoS One, vol. 14, no. 5, pp. e0216862, 2019.
Datei:pdfhttps://www.ncbi.nlm.nih.gov/pubmed/31086407 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6516676/pdf/pone.0216862.pdf
M. Wlaschek, K. Singh, A. Sindrilaru, D. Crisan and K. Scharffetter-Kochanek, "Iron and iron-dependent reactive oxygen species in the regulation of macrophages and fibroblasts in non-healing chronic wounds", Free Radic Biol Med, vol. 133, pp. 262-275, 2019.