Nutzung des menschlichen Peptidoms zur Entwicklung neuer antimikrobieller und anti-Krebs Therapeutika

Das menschliche Peptidom (d.h. die Gesamtheit aller Peptide im menschlichen Körper) umfasst Millionen verschiedener Verbindungen, die zahlreiche physiologische und pathologische Prozesse steuern. Peptide sind insbesondere Schlüsselregulatoren und Effektoren der angeborenen und adaptiven Immunität und modulieren das Überleben und die metastatische Ausbreitung von Krebszellen. Bis heute wurde nur ein kleiner Teil aller endogenen Peptide funktionell charakterisiert. Somit stellt das Peptidom eine kaum erforschte und nahezu unbegrenzte Quelle für die Entdeckung neuer Bioeffektoren dar. Hauptziel des beantragten SFB ist es daher, das menschliche Peptidom zur Entdeckung von Peptiden zu nutzen, die wichtig für die Abwehr und Bekämpfung von Infektionserkrankungen und Krebs sind und diese mittels neuer Technologien für translationale in vivo Anwendungen zu optimieren.

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Aktuelles


And the Poster Award goes to … Dr. Janis Müller

Dr. Janis Müller received one of two Poster Prizes at the 29th Annual Meeting of the German Society for Virology (GfV) in Düsseldorf, Germany.


by Kristina Hopfensperger | March 28, 2019


Time to say goodbye… and hello Kristina!

Annika Röcker, so far responsible for Public Relations and Event reports of the CRC homepage, will leave us by the end of March 2019. Luckily, Kristina Hopfensperger will take over.

by Dr. Annika Röcker, Kristina Hopfensperger and Prof. Dr. Frank Kirchhoff


Prof. Holger Barth in action

Together with Prof. Matthias Schwab from the Fischer-Bosch Institute of ClinicaI Pharmacology in Stuttgart, our PI Prof. Holger Barth chairs the 4th German Pharm-Tox Summit.

by Dr. Annika Röcker | March 06, 2019



Much more than Amyloid β

From February 19th to 21th, CRC1279 board member Prof. Dr. Marcus Fändrich, director of the Institute of Protein Biochemistry, chaired the 3rd Meeting on Biophysics of Amyloid Formation.

by Dr. Annika Röcker & Kristina Hopfensperger | March 05, 2019



Online now: Konstantin Sparrer’s research objective

Dr. Konstantin Sparrer had been awarded with a „Young Investigator Fund for Innovative Research Ideas“ of the Schering Stiftung and the Fritz Thyssen Foundation.

by Dr. Annika Röcker | 21.02.2019



“Should I Stay or Should I Go?”

An interdisciplinary team at Ulm University analyzed the DNA binding behavior of the transcription factor serum response factor (SRF) at single-molecule resolution.

by Dr. Annika Röcker | 04.02.2019



About dream teams: Scientist couple explores Host-Microbe interactions

Prof. Hinterleitner and Prof. Meisel from the University of Pittsburgh gave a lunch seminar addressing the topics: “Woman in academia: Transitioning from a postdoc to group leader/professor”

by Dr. Annika Röcker | 14.01.2019



With Bachelor’s degree straight towards PhD

Due to her exceptional performance, she was allowed to start her PhD directly after her undergraduate studies. Lisa is a perfect example for a young, ambitious woman in science!

by Dr. Annika Röcker | 11.01.2019



Kontakt



SFB Geschäftsstelle
Kristina Wohllaib
Tel.: 0731 500 65151
mail: kristina.wohllaib@uni-ulm.de


Sprecher:
Kirchhoff, Frank, Prof. Dr.
Institute of Molecular Virology
Ulm University Medical Center
Meyerhofstr. 1
89081 Ulm
Tel.: 0731 50065150
mail: frank.kirchhoff@uni-ulm.de

    CRC 1279 Upcoming Events


  • 25th of March 2019
    CRC 1279 Monday Seminar series with Prof. Holger Barth

    “Human and microbial peptides as novel inhibitors of bacterial toxins“
    Place: Multimedia Room, N27 Time: 15h00
  • 1st of April 2019
    CRC 1279 Monday Seminar series with Prof. Karl-Klaus Conzelmann

    “The Extendables: Exploiting the skills of rabies virus to turn ancient foes into allies“
    Place: Multimedia Room, N27 Time: 15h00
  • 2nd of April 2019
    Wine and Cheese meeting

    open for PhD students and postdocs involved in the CRC
    Place: N27 Time: 17h00
  • 8th of April 2019
    CRC 1279 Monday Seminar series with Dr. Han Li - Time: 14h00

    “Cellular Plasticity in cancer and ageing“
    Place: Multimedia Room, N27 Time: 14h00
  • 15th of April 2019
    CRC 1279 Monday Seminar series with Prof. Elisabetta Traggiai

    “Learning from self and non self human memory BCR repertoire“
    Place: Multimedia Room, N27 Time: 15h00
  • 29th of April 2019
    CRC 1279 Monday Seminar series with Prof. Andrea Pauli

    “Small proteins with big roles – from coordinating cell migration to mediating species-specific fertilization“
    Place: Multimedia Room, N27 Time: 15h00

  • For more information and previous CRC1279 Monday Seminars klick here

Building the CRC1279 Webpage


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Public Relations and Content

Kristina Hopfensperger: kristina.hopfensperger@uni-ulm.de
PhD student at the institute of Molecular Virology Ulm


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Web Design and Content

Dr. Dré van der Merwe:
dre.van-der-merwe@uni-ulm.de
Lab Manager at the institute of Molecular Virology Ulm


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Web Design

Fabian Zech:
fabian.zech@uni-ulm.de
PhD student at the institute of Molecular Virology Ulm

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