The estimand concept of ICH E9 (R1) and its counterpart in causal statistics

Time : Monday , 9.12.2019, 16:00 - 17:00 Uhr
Location : Universität Ulm, N24, Hörsaal 15

Speaker: Prof. Dr. Ulrich Mansmann, Direktor des Instituts für Medizinische Informationsverarbeitung, Biometrie und Epidemiologie der LMU München)

My presentation will present the recently introduced estimand concepts for the interpretation of clinical trials outcomes under the focus of causal theory. We will discuss issues like "principle strata" and provide some discussion of the concept of the "Per Protocol Analysis". The role of "assumptions made" will be highlighted as well as the implications on protocol and data management when using causal statistics to analyze clinical trial data.

Veranstaltung im Rahmen des Ringseminars "Methoden der Epidemiologie, Biometrie und Versorgungsforschung"